• Title/Summary/Keyword: Innovation in S&T

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A Content Analysis on the S&T Comprehensive Plans in Korea: Focusing on Five-Year Plans (한국의 과학기술종합계획에 관한 내용분석 : 5개년 계획을 중심으로)

  • Song, Sung-Soo
    • Journal of Science and Technology Studies
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    • v.7 no.1
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    • pp.117-150
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    • 2007
  • This paper attempted a content analysis on the S&T comprehensive plans in Korea focusing on five-year plans. They include twelve plans from the 1st five-year plan for technological promotion(19621966) to S&T basic plan in participatory government(20032007). The result of content analysis on such plans was explained according to policy environments, formative system, policy goals, policy scopes, and policy subjects. In the case of policy subjects, this paper reconstructed nine policy categories such as national strategic technology development, S&T investment, S&T manpower, basic science research, private technology development, international S&T cooperation, regional S&T innovation, S&T infrastructure, and S&T culture. In conclusion, this paper proposed future directions for the making of S&T comprehensive plans in Korea.

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The Anti-adipogenic and Lipolytic Effect of Jinkyool (Citrus sunki Hort. ex Tanaka) Leaf Extract in 3T3-L1 Cells (3T3-L1 지방세포에서 진귤 잎 유래 polymethoxyflavones 다량 함유 분획물(PRF)의 항지방생성 및 지방분해 효과)

  • Jin, Yeong Jun;Jang, Mi Gyeong;Kim, Jae-Won;Kang, Minyeong;Ko, Hee Chul;Kim, Se Jae
    • Journal of Life Science
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    • v.32 no.7
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    • pp.542-549
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    • 2022
  • Polymethoxyflavones (PMFs) are flavonoids mainly found in citrus fruits and have been reported to exhibit a wide range of bioactivities, including anti-obesity, anti-cancer, and anti-inflammatory actions. To utilize PMFs as functional materials, it is necessary to develop a simple method of obtaining PMFs from citrus tissues containing a large amount of PMFs. It has been reported that Jinkyool (C. sunki Hort ex. Tanaka) peel contained a large amount of PMFs, but there are no studies on PMFs isolated from its leaves. In this study, we established a simple procedure for obtaining the PMF-rich fraction (PRF) from the leaves of Jinkyool and investigated the effects of PRF on lipid metabolism in 3T3-L1 cells. PRF inhibited lipogenesis during the differentiation of 3T3-L1 preadipocytes. It decreased the expression of peroxisome proliferator-activated receptor gamma (PPAR𝛾) and CCAAT/enhancer binding protein alpha (CEBP𝛼), FAS, and adipocyte fatty-acid-binding protein 2 (aP2). In mature 3T3-L1 adipocytes, PRF increases the phosphorylation of protein kinase A (PKA)/hormone-sensitive lipase (HSL), which are key factors involved in lipolysis. Moreover, it increases the phosphorylation of the AMP-activated protein kinase (AMPK)/acetyl-CoA carboxylase (ACC) involved in fatty acid oxidation. These results suggest that PRF from Jinkyool leaves can be used as an anti-obesity agent with the action of inhibiting lipogenesis and promoting lipolysis and fatty acid oxidation in 3T3-L1 adipocytes.

BSC Analysis of Performance Measurement Systems of Government S&T Research Institutes (BSC 관점을 활용한 출연연구기관 평가제도의 수용성 연구)

  • Kim Byung-Tae;Nam Young-Ho
    • Journal of Korea Technology Innovation Society
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    • v.8 no.3
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    • pp.1087-1116
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    • 2005
  • This research examines performance evaluatees' opinions regarding the institutional performance evaluation systems of Government S&T Research Institutes (GRI). Research methodology is as follows: first, four perspectives of Kaplan & Norton (1992) Balanced Scorecard Model are revised into six perspectives suitable to GRI's characteristics. Second, experts classify current performance evaluation measures into the six perspectives. This enables different evaluation systems of three GRI evaluation groups to be compared under the same evaluation measures. Third, GRI's evaluatees are asked to allocate ideal weights on the performance measures. The evaluatees' weights are compared with the weights of current performance measures, and the characteristics of evaluatees' opinions about current performance evaluation systems are analyzed. Results are as follows; first, six perspectives for Korean GRIs are financial, long-term outcome, short-term outcome, strategic direction, project management, human resources perspectives. second, GRI evaluation systems put the most weights on the long- and short-term outcome perspectives and the least weights on the financial perspective. This result complies with theoretical model: in performance evaluation of GRIs, the customer perspective is the most important one while the financial perspective is the least important one. Third, evaluatees think that the long-term outcome perspective of the Basic-technology GRI group and the short-term outcome perspective of the Applied-technology GRI Group needs more weight. Fourth, it is found that the current systems have more weights on the project management and strategic direction perspectives than evaluatees think. The possible explanation of this result would be that since the measures of these perspectives are relatively easier to set up than those of other perspectives, the current systems contains larger number of measures and, accordingly more weights.

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The effects of employee's success experience on business performance in six sigma activities (6시그마 혁신활동에 있어서의 구성원 성공체험이 기업성과에 미치는 영향)

  • Yi, Ran-Young;Shin, Ik-Ju
    • Journal of Korean Society for Quality Management
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    • v.37 no.3
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    • pp.10-17
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    • 2009
  • This study developed a new model for evaluating effects about the success of six sigma activities. This model consists of four constructs such as success of six sigma, employee's success experience, customer satisfaction, and business performance. Structural Equation Modeling (SEM) is used to analyze causality among the four constructs. Hypothesis were tested through a field study conducted for one hundred and thirty-one project leaders, who were asked to evaluate their experiences of six sigma projects. The results indicate that six hypothesis are statistically significant. As a result, the success of six sigma doesn't influence the customer satisfaction directly, but it influences customer satisfaction indirectly through employee's success experience. We find out that control for employee's success experience is important as well as success of six sigma in business innovation. Otherwise business performance is influenced directly by success of six sigma, that is business performance isn't influenced directly by employee's success experience but influenced indirectly through customer satisfaction. This study found that the change management raising employee's success experience is important in Six Sigma.

Comparative Analysis of Offensive Odorants in Urine Samples in Relation to Sample Treatment Conditions (Urine 시료 중 지정악취성분에 대한 분석연구: 시료의 보관방법과 채취조건의 연계성 연구)

  • Lee, Min-Hee;Kim, Yong-Hyun;Jo, Sang-Hee;Choi, Si-On;Sa, Inyoung;Kim, Ki-Hyun
    • Journal of Korean Society for Atmospheric Environment
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    • v.30 no.5
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    • pp.492-503
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    • 2014
  • In this study, emission characteristics of volatile odorant species released from urine samples were investigated in relation to two key variables: [1] storage conditions before sampling and [2] incubation conditions during sampling. To this end, 20 offensive odorants were quantified by four different analytical systems and then sorted according to seven functional groups. It is indicated that benzene (B), styrene (S), isobutyl alcohol (i-BuAl), butyl acetate (BuAc), butyraldehyde (BA), isovaleraldehyde (IA), and valeraldehyde (VA) did not contribute to urine odor because their concentration levels were measured below detection limits in all samples. On the other hand, emission concentrations of toluene (T), methyl ethyl ketone (MEK), methyl mercaptan (CH3SH), carbon disulfide (CS2), and ammonia (NH3) were generally higher than other compounds. In terms of odor intensity (OI), CH3SH and NH3 showed the largest OI values in the range of 2~4. According to t-test (storage approach and urine temperature), the results of T, CS2, and NH3 were statistically distinguished from each other in terms of differences in sampling temperature. Likewise, the emissions of certain odorants from urine samples were affected by changes in sample treatment conditions to a degree.

An Increase in University Patents and the Role of the State (대학의 특허 출원 증가와 국가의 역할)

  • Bae, Tae-Sup
    • Journal of Science and Technology Studies
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    • v.11 no.1
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    • pp.31-59
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    • 2011
  • This paper examines university patenting activities as a commercialization of academic research. It shows how a number of university patents increase exponentially and how that can be, especially in terms of role of the state. In the late 1990, the Korean government supports the new vision of 'technological innovation' in establishing a science and technological policy and begins to perceive the importance of university R&D to overcome the economic crisis. Thus, an administrative, financial, and legal systems which support the university R&D are organized and the governmental grants for R&D increase exponentially, especially in promising new technologies(6T). Also, an institution for managing intellectual property rights is established in university. Universities assess professor's performance in terms of patent and license to encourage patenting activities. Thus the number of patents and its productivity increase exponentially. But the increase in patents takes place only to a dozen of universities, this means that a Matthew effect does work.

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The Impact of Corporate Strategies and Government Support Policies on the Corporate Performance: Focusing on Certification of Innovation (기업의 전략 및 정부 지원 정책이 기업 성과에 미치는 영향: 혁신형 인증을 중심으로)

  • Kim, Dae Jin;Park, Da in
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.11 no.1
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    • pp.13-27
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    • 2016
  • Companies strive to have the ability to flexibly respond to environmental changes in modern society with its rapidly changing business environment. That is, companies try to achieve the corporate performance by using a variety of strategies since companies that don't go along with changes in industry are likely to fall behind. Also, the corporate performance is a key element in national competitiveness, and government is willing to support companies to maximize their performance in various ways. This study examines whether there is a difference between corporate strategies and government policies according to the retention and the type of certification of innovation. The company's strategy configuration effort is largely divided into exploration and exploitation of external knowledge, while the government's policy is divided into direct support, indirect support, and financial support. The corporate performance is analyzed using technological performance; innovative perspective and the sales; and the actual corporate performance as proxy variables. As a result, the variable affecting the performance differs according to the retention of certification of innovation. The variable affecting the corporate performance differs according to the type of certification of innovation as well. Therefore, it was found that companies can achieve the corporate performance by considering the situation at hand and the differentiated action strategies depending on the type of certification of innovation.

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A Study on Strategies of Public R&D to Achieve National Carbon Neutrality: Focusing on the Implications of the Republic of Korea

  • Song, Jaeryoung;Kim, Cheolhu
    • Asian Journal of Innovation and Policy
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    • v.11 no.1
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    • pp.1-29
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    • 2022
  • Climate action is at the top of the agenda in the international community, as demonstrated at the 2021 G7 Summit and the 2021 UN Climate Summit. Major developed countries are scrambling to make a transition to a green economy and create a new growth momentum. Following the Paris Climate Agreement in 2016, they focus on "carbon neutrality" as an effective means of tackling climate change. The Republic of Korea, a high-carbon economy, submitted its second Nationally Determined Contribution and announced carbon neutrality as a top policy priority. Accordingly, the country increases government budget in research and development (R&D) and science and technology (S&T) policies. Against this backdrop, this study analyzed policies on carbon-neutral S&T and R&D in major advanced countries. The analysis was made by identifying globally pending issues in carbon-neutral policies and climate technology. In addition, focus group interviews were conducted six times with 10 experts to come up with three R&D strategies and action plans for government-funded research institutes to achieve carbon neutrality. To be specific, the following measures were suggested. First, creative and innovative R&D programs are required to solve the problem of carbon emissions. Second, it is necessary to establish carbon neutrality policies and infrastructure which are sustainable to run and manage. Third, it is crucial to promote cooperation in climate technology based on excellence. In conclusion, the strategies proposed in this study are expected to provide directions and implications for policymakers, researchers, and scholars in science and technology to develop effective strategies to achieve national carbon neutrality.

Panax ginseng total protein promotes proliferation and secretion of collagen in NIH/3T3 cells by activating extracellular signal-related kinase pathway

  • Chen, Xuenan;Wang, Manying;Xu, Xiaohao;Liu, Jianzeng;Mei, Bing;Fu, Pingping;Zhao, Daqing;Sun, Liwei
    • Journal of Ginseng Research
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    • v.41 no.3
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    • pp.411-418
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    • 2017
  • Background: Recently, protein from ginseng was studied and used for the treatment of several kinds of diseases. However, the effect of ginseng total protein (GTP) on proliferation and wound healing in fibroblast cells remains unclear. Methods: In this study, cell viability was analyzed using the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay. Cell cycle distribution was analyzed by flow cytometer. The levels of transforming growth factor β1, vascular endothelial growth factor, and collagens were analyzed by enzyme-linked immunosorbent assay and immunofluorescence staining. The expressions of cyclin A, phosphorylation of extracellular signal-related kinase (p-ERK1/2), and ERK1/2 were analyzed by Western blotting. Results: Our results showed that GTP promoted cell proliferation and increased the percentage of cells in S phase through the upregulation of cyclin A in NIH/3T3 cells. We also found that GTP induced the secretion of type I collagen, and promoted the expression of other factors that regulate the synthesis of collagen such as transforming growth factor β1 and vascular endothelial growth factor. In addition, the phosphorylation of ERK1/2 at Thr202/Tyr204 was also increased by GTP. Conclusion: Our studies suggest that GTP promoted proliferation and secretion of collagen in NIH/3T3 cells by activating the ERK signal pathway, which shed light on a potential function of GTP in promoting wound healing.