• Journal of Auto-vehicle Safety Association
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• v.6 no.1
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• pp.41-47
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• 2014

A new dummy has improved biofidelity from Fair to Good compare with EuroSID2re which is currently used for regulation tests and NCAP tests. Some instrumentation of each body region has been changed to measure the assessment of injury risk. The objective of this study is to find out the injury characteristic of each dummy and to calculate the relation between external force and injury for each dummy with pendulum tests. Finally, this study suggests the optimized external force to meet consumer tests. A new dummy named WorldSID for side impact will be introduced into EuroNCAP tests after 2015. Korea government is also planning to adopt WorldSID at KNCAP tests from 2017 and Global Technical Regulation (GTR) will also adopt WorldSID to oblique side pole crash.

• Natural Product Sciences
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• v.28 no.4
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• pp.194-200
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• 2022

Albizia julibrissin Durazz. (AJ; family Minosaceae) is widely distributed worldwide, and its stem bark has been used as a traditional herbal medicine. Acute kidney injury (AKI) is a clinical syndrome that results in sudden loss of renal function. This study aimed to investigate the effects of AJ against cisplatin-induced AKI using a human kidney proximal tubule epithelial cell line (HK-2) and cisplatin-treated mice. In vitro, cisplatin treatment increased apoptosis in HK-2 cells. However, AJ treatment decreased apoptosis of cisplatin-treated HK-2 cells. In vivo, cisplatin treatment accelerated renal injury by increasing the levels of renal injury markers, such as blood urea nitrogen, creatinine, kidney injury molecule 1, and neutrophil gelatinase-associated lipocalin, which were reversed by AJ treatment. Histopathologically, AJ treatment resulted in decreased renal damage with less tubular necrosis and brush border desquamation compared with the AKI group. Additionally, cisplatin treatment upregulated mitochondrial fission, a pathological characteristic of AKI, which was downregulated by AJ treatment. Along with increased mitochondrial fission, AJ treatment also reduced cisplatin-induced apoptosis. These results suggest that AJ may be a potential therapeutic agent for cisplatin-induced AKI.

• Journal of Trauma and Injury
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• v.19 no.1
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• pp.35-40
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• 2006

Purpose: Injuries are the third leading cause of death in Korea. Isolated chest injury is not uncommon and shows high mortality and morbidity. Several scoring systems are used for triage and stratification for trauma patients, but no standard system is accepted. We aimed to analyze the accuracy of identification of isolated chest injury by using several scoring systems. Methods: We reviewed a total of 75 patients admitted with isolated chest injury between January 2005 and October 2005. Medical records were reviewed by using the Injury Severity Score (ISS), the Revised Trauma Score (RTS), and the Trauma and Injury Severity Score (TRISS). The scoring systems were compared by using statistics methods. Results: The overall predictive accuracy of the TRISS was 12.5%, 12.0% greater than those of the RTS and the ISS. By using the area under the receiver operating characteristic (AUROC) curve, the TRISS showed an excellent discriminative power (AUROC 0.931) compared to the ISS (AUROC 0.926) and the RTS (AUROC 0.872). Conclusion: Compared with the RTS and the ISS, the TRISS is an easily applied tool with excellent prognostic abilities for isolated chest trauma patients. However, the TRISS, the ISS, and the RTS showed high specificity and low sensitivity, so another scoring system is required for triage and stratification of isolated chest injury patients.

• The Journal of Korean Medicine
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• v.27 no.4
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• pp.116-124
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• 2006

Peripheral nerve injuries are a commonly encountered clinical problem and often result in chronic pain and severe functional deficits. At the Dept. of Oriental Rehab. Medicine, we have used for pain control a herbal bath containing the following herbs: Harpagophytum radix, Atractylodes japonica and Corydalis tuber. In the present study, we investigated the effects of this herbal bath on the recovery rate of the locomotor function and the expression of c-Fos in the ventrolateral periaqueductal gray (vIPAG) region of the brain following sciatic crushed nerve injury in rats. In the present study, characteristic gait change with decreasing of the sciatic function index (SFI) was observed and c-Fos expression in the vIPAG was suppressed following sciatic crushed nerve injury in rats. Immersion into herbal bath enhanced SFI value and restored c-Fos expression in the vIPAG to the control value. These results suggest the herbal bath might activate neurons in the vIPAG, and could facilitate functional recovery from peripheral nerve injury.

• Journal of Trauma and Injury
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• v.21 no.2
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• pp.71-77
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• 2008

Purpose: The Glasgow Coma Scale (GCS), though it is widely used for triage, has been criticized as being unnecessarily complex. Recently, a 3-point Simplified Motor Score (SMS, defined as obeys commands=2; localizes pain=1; withdrawals to pain or worse=0) was developed from the motor component of the GCS and was found to have a similar test performance for triage after traumatic brain injury when compared with the GCS as the criterion standard. The purpose of this study was to validate the SMS. Methods: We analyzed the patients who visited Kyungpook National University Hospital emergency center after traumatic brain injury from 2006 January to 2006 June. The test performance of the GCS, its motor component, and SMS relative to three clinically relevant traumatic brain injury outcomes (abnormal brain CT scans, Abbreviated Injury Scale $(AIS){\geq}4$, and mortality) were evaluated with areas under the receiver operating characteristic curves (AUCs). Results: Of 504 patients included in the analysis, 25.6% had an abnormal brain CT scans, 13.1% had $AIS{\geq}4$, and 5.0% died. The AUCs for the GCS, its motor component, and SMS with respect to the abnormal CT scans were 0.776, 0.715, and 0.716, and respectively, those for $AIS{\geq}4$ and mortality, were 0.969, 0.973, and 0.968, and 0.931, 0.909, and 0.909, respectively. Conclusion: The 3-point SMS demonstrated similar test performance when compared with the 15-point GCS score and its motor component for triage after traumatic brain injury in our populations.

• Toxicological Research
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• v.22 no.4
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• pp.323-328
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• 2006

Global gene expression profile was analyzed by microarray analysis of rat liver RNA after acute acetaminophen (APAP) administration. A single dose of 1g/kg body weight of APAP was given orally, and the liver samples were obtained after 24, 48 h, and 2 weeks. Histopathologic and biochemical studies enabled the classification of the APAP effect into injury (24 and 48 h) and regeneration (2 weeks) stages. The expression levels of 4900 clones on a custom rat gene microarray were analyzed and 484 clones were differentially expressed with more than a 1.625-fold difference(which equals 0.7 in log2 scale) at one or more time points. Two hundred ninety seven clones were classified as injury-specific clones, while 149 clones as regeneration-specific ones. Characteristic gene expression profiles could be associated with APAP-induced gene expression changes in lipid metabolism, stress response, and protein metabolism. We established a global gene expression profile utilizing microarray analysis in rat liver upon acute APAP administration with a full chronological profile that not only covers injury stage but also later point of regeneration stage.

• Korean Journal of Health Education and Promotion
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• v.14 no.1
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• pp.147-160
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• 1997

Nowadays according to the complexity of our daily life due to the development of industry and transportation various kinds of injuries happen. Since 1993 the death rate among 5-14 age children by injuries amount to about 57%. Furthermore, the injury of children can give a direct damage to their own family and it can also bring a serious loss to the country as well as the community where they live in accord with degree of an injury. From this reason, the importance of safety education has been increasing. In this study, it is aimed to clarify the effect of injury preventive behaviors on injury incidence of the 6th grade students in the elementary school. This study is accomplished by the survey sampled from 9 elementary schools in seoul, each of which belong to different district. The survey took for 15 days from the date of september 10th 1996 to september 25th 1996 and the results were as follows; 1. For demographic characteristic, sexual distribution was 48.7% of male students and 47.1% of female students. The required time from home to school was 10-19 minutes(51.8%), and the most way of their going to school is to walk(89.7%). Mothers who graduated from high school were 46.6% and 49.4% of fathers were above university graduated level. The most vocation of mothers was housewife as 56.7%. 2. The results of analysis on the injury rates, 75.8% of children experienced more than one injury and the most was play injury. With regards to sites where injuries happened, the room, the kitchen, and the living room in the house ranked first(38.3%) and then injuries at school such as on the playground, in the classroom, and on the stairs was 34.1%. 3. Considering the rate of injury incidence in accordance with demographic characteristics, male students experienced more injuries than female students(p〈0.05). For the way from home to school, children who went to school by bicycle experienced the most injuries and then on foot, by bus in order of which differences were statistically significant(p〈0.05). 4. From the comparison of parents' safety education practice and the injury incidence, the less often parents practice safety education, the more often children experience injuries(p〈0.05). 5. The results of analysis on the effect of injury preventive behaviors on accidents children who didn't act injury preventive behaviors experienced much more injuries than those who did injury preventive behaviors of which differences were statistically significant(p〈0.01). 6. From the results of analysis of factors effecting on the elementary school children's injuries, children without injury preventive behaviors had more effect on accidents than those who had injury preventive behaviors as odds ratio 2.06(p〈0.01), and the odds ratio of male students compared with female students was 1.47(p〈0.05).

• Archives of Plastic Surgery
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• v.38 no.1
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• pp.113-116
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• 2011

Purpose: Many fingertip injuries are associated with nail injury and it is hard to repair to original shape due to its unique characteristic. Mucosal graft is used for a defect of the nail bed injury. Hereby, we introduce a DAP flap and buccal mucosal graft, with which we could reduce the defect size of the injured fingertip and donor site morbidity at the same time, without any need for harvesting additional skin from other part of hand. Also, mucosal graft makes good cosmetic and functional outcome of nail. Methods: This method was performed in a 56-year-old man with fingertip injury on dorsal side of left thumb due to electrical saw. First, DAP flap was performed on the injured finger to reduce the size of the defect of fingertip and cover the bone exposure. Second, nail bed part of the DAP flap was de-epithelized and buccal mucosal graft was done from left side of intraoral cavity wall. Results: Flap and graft survived without any necrosis but some nail bed could not be covered with flap due to insufficient flap size. All wounds healed well and did not present any severe adversary symptoms. Conclusion: DAP flap with mucosal graft is an effective method that we can easily apply in reconstruction of fingertip injury. We suggest that the combination of the two procedures makes good functional and cosmetic outcome compared to the usual manner, especially in cases of nail bed injury without distal phalanx bone defect.

• The Journal of Korean Physical Therapy
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• v.34 no.6
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• pp.326-331
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• 2022

Purpose: The stroke patients have gait dysfunction due to impaired neural tracts; corticospinal tract (CST), corticoreticular pathway (CRP), and vestibulospinal tract (VST). In this study, we investigated characteristics of gait pattern according to the injury aspect of the neural track in a stroke patient. Methods: One patient and six control subjects of similar age participated. A 19-year-old male patient with spontaneous intracerebral hemorrhage on right basal ganglia, thalamus, corona radiata and cerebral cortex due to arteriovenous malformation rupture. Diffusion tensor imaging (DTI) data was acquired 21 months after the stroke. Kinematic and spatio-temporal parameters of gait were collected using a three-dimensional gait analysis system. Results: On 21 months DTI, the CST and CRP in affected hemisphere showed severe injury, in contrast, the VST in affected hemisphere showed intact integrity. Result of gait analysis, walking distance and speed were significantly decreased in a patient. The stance rate of unaffected lower limb, the swing rate of affected lower limb and the duration of double stance significantly increased compared with normal control. The knee and hip joint angle were significantly decreased in a patient. Conclusion: We found recovered independent gait ability may be associated with unimpaired VST in a patient with severe injury in CST and CRP.

• 한국체육학회지인문사회과학편
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• v.58 no.2
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• pp.405-416
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• 2019

This study aimed to identify the efficiency of short track-related sports injury prevention program consisted of muscle strength and neuromuscular training on non-contact injury incidence and characteristics in knee and ankle joints and low back for elite short track speed skaters. Twenty-five short track athletes who belonged to G-City Team were participated in this study from Nov. 2017 to Jul. 2018. Information on their sports injuries occurred were collected and injury prevention program was applied in their warm-up every training sessions and competition. Also their symptom-level of knee and ankle joint and low back were measured by using OSTRC overuse injury questionnaire and Cumberland ankle instability(CAIT). The injury incidence rate after application of prevention program was 2.79 injuries/1,000 hour exposures(HEs), which was lower than before (3.04 injuries/1,000HEs). The OSTRC score (30.89±28.34 and 23.84±23.61, respectively) in knee and low back after application of prevention program were lower than before (58.47±26.77 and 52.36±21.55, respectively), and the CAIT score (13.47±6.07) in ankle joint after application of program was higher than before (16.26±7.28), which means that their symptom-level was alleviated with sports injury prevention program. In conclusion, the sports injury prevention program designed for short track's motion and characteristic can have positive influences on the occurrence of non-contact injury for short track speed skaters.