• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.271-272
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• 1998

Contrast-enhanced CT has an important role in the assessment of liver lesions. However, the optimal protocol to get most effective result is not clear. The main principle for deciding injection protocol is to optimize lesion detectability by rapid scanning when lesion-to-liver contrast is maximum. For this purpose, we developed a physiological model of contrast medium enhancement based on the compartment modeling and pharmacokinetics. Blood supply to liver was modeled in two paths. This dual supply character distinguishes the CT enhancement of liver from that of the other organs. The first path is by hepatic artery and the second is by portal vein. It is assumed that only hepatic artery can supply blood to hepatocellular carcinoma (HCC) compartment. It is known that this causes the difference of contrast enhancement between normal liver tissue and hepatic tumor. By solving differential equations for each compartment simultaneously using computer program Matlab, CT contrast-enhancement curves were simulated. Simulated enhancement curves for aortic, hepatic, portal vein, and HCC compartments were compared with mean enhancement curves from 24 patients exposed to the same protocols as simulation. These enhancement curves were in a good agreement. Furthermore, we simulated lesion-to-liver curves for various injection protocols, and analyzed the effects. These may help to optimize the scanning protocols for good diagnosis.

• Nuclear Engineering and Technology
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• v.50 no.3
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• pp.356-367
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• 2018

A series of tests dedicated to station blackout (SBO) accident scenarios have been recently performed at the $Prim{\ddot{a}}rkreislauf-Versuchsanlage$ (primary coolant loop test facility; PKL) facility in the framework of the OECD/NEA PKL-3 project. These investigations address current safety issues related to beyond design basis accident transients with significant core heat up. This work presents a detailed analysis using the best estimate thermal-hydraulic code TRACE (v5.0 Patch4) of different SBO scenarios conducted at the PKL facility; failures of high- and low-pressure safety injection systems together with steam generator (SG) feedwater supply are considered, thus calling for adequate accident management actions and timely implementation of alternative emergency cooling procedures to prevent core meltdown. The presented analysis evaluates the capability of the applied TRACE model of the PKL facility to correctly capture the sequences of events in the different SBO scenarios, namely the SBO tests H2.1, H2.2 run 1 and H2.2 run 2, including symmetric or asymmetric secondary side depressurization, primary side depressurization, accumulator (ACC) injection in the cold legs and secondary side feeding with mobile pump and/or primary side emergency core coolant injection from the fuel pool cooling pump. This study is focused specifically on the prediction of the core exit temperature, which drives the execution of the most relevant accident management actions. This work presents, in particular, the key improvements made to the TRACE model that helped to improve the code predictions, including the modeling of dynamical heat losses, the nodalization of SGs' heat exchanger tubes and the ACCs. Another relevant aspect of this work is to evaluate how well the model simulations of the three different scenarios qualitatively and quantitatively capture the trends and results exhibited by the actual experiments. For instance, how the number of SGs considered for secondary side depressurization affects the heat transfer from primary side; how the discharge capacity of the pressurizer relief valve affects the dynamics of the transient; how ACC initial pressure and nitrogen release affect the grace time between ACC injection and subsequent core heat up; and how well the alternative feeding modes of the secondary and/or primary side with mobile injection pumps affect core quenching and ensure stable long-term core cooling under controlled boiling conditions.

• Korea-Australia Rheology Journal
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• v.20 no.2
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• pp.59-63
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• 2008

A theoretical model was developed to describe the flow behavior of a filled polymer in the packing stage of reaction injection molding and predict the residual stress distribution of thin injection-molded parts. The model predictions were compared with experiments performed for phenol-formaldehyde resin filled with wood dust and cured by urotropine. The packing stage of reaction injection molding process presents a typical example of complex non-isothermal flow combined with chemical reaction. It is shown that the time evolution of pressure distribution along the mold cavity that determines the residual stress in the final product can be described by a single 1D partial differential equation (PDE) if the rheological behavior of reacting liquid is simplistically described by the power-law approach with some approximations made for describing cure reaction and non-isothermality. In the formulation, the dimensionless time variable is defined in such a way that it includes all necessary information on the cure reaction history. Employing the routine separation of variables made possible to obtain the analytical solution for the nonlinear PDE under specific initial condition. It is shown that direct numerical solution of the PDE exactly coincides with the analytical solution. With the use of the power-law approximation that describes highly shear thinning behavior, the theoretical calculations significantly deviate from the experimental data. Bearing in mind that in the packing stage the flow is extremely slow, we employed in our theory the Newtonian law for flow of reacting liquid and described well enough the experimental data on evolution of pressure.

• Journal of the Korean Society for Precision Engineering
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• v.29 no.2
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• pp.222-228
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• 2012

Haptics and virtual reality are rapidly growing technologies in medical fields. Physicians and nurses can benefit from medical simulation via training and acquire surgical and clinical techniques. In this paper, the research on needle insertion force of biological tissue for haptic based intravenous injection simulator was carried out. We built the setup for needle insertion (intravenous injection) experiments and performed the experiments on live pigs. The force responses against needle insertion were measured using the experimental setup. In addition, the modeling of needle insertion force was carried out with the experimental results and numerical models via nonlinear least-squares method. The results presented in this paper indicate that the developed models can be applied not only to estimate the force feedback during intravenous injection procedure but also to improve the overall training quality of the medical simulator.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.2
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• pp.340-348
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• 2002

Deformation analysis of injection molded articles whose geometry is considered as the assembly of thin flat plates has been conducted. For the in-mold analysis, thermo-viscoelastic stress calculation of thermo-rheologically simple amorphous polymer and in-mold deformation calculation considering the in-plane mold constraint have been done. Free volume theory has been used to represent the non-equilibrium density state during the fast cooling. At ejection, instantaneous deformation takes place due to the redistribution of in-mold residual stress. During out-of-mold cooling after ejection, thermoelastic model based on the effective temperature has been adopted for the calculation of out-of-mold deformation. In this study, emphasis is also made on the treatment with regard to lateral constraint types during molding process. Two typical mold geometries are used to test the numerical simulation modeling developed in this study.

• Journal of the Korean Society for Precision Engineering
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• v.26 no.2
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• pp.54-62
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• 2009

The purpose of this study is to develop a piezo injector driver for common-rail direct injection diesel engines. In this research, we analyzed the electrical and mechanical characteristics of the piezo actuator through experiments. Current flow and charging voltage of the piezo injector are controlled by the PWM signal of variable duty ratio in order to realize both fast response and low peak current. The optimal switching duty ratio was designed by modeling and analyzing of the piezo driver circuit. In order to avoid resonance and unacceptably long settling time, appropriate frequency range of the PWM signal was derived based on the driver circuit model. The developed injector driver was validated by experiments under various fuel rail pressure, injection duration, and charging voltage.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.12
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• pp.2079-2084
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• 2003

In biological cell manipulation, manual thrust or penetration of an injection pipette into an embryo cell is currently performed by a skilled operator, relying on visual feedback information only. Accurately measuring cellular forces is a requirement for minimally invasive cell injections. Moreover, the cellular force sensing is essential in investigating the biophysical properties for cell injury and membrane modeling studies. This paper presents cellular force measurements for the force feedback-based biomanipulation. Cellular force measurement system using piezoelectric polymer sensor is implemented to measure the penetration force of a zebrafish egg cell. First, measurement system setup and calibration are described. Second, the force feedback-based biomanipulation is experimentally carried out. Experimental results show that it successfully supplies real-time cellular force feedback to the operator at tens of uN and thus plays a main role in improving the reliability of biological cell injection tasks.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.3
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• pp.137-146
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• 1997

Spray characteristics of high pressure injectors for diesel engines have been experimentally studied with special emphasis on the effect of swirl. A constant volume chamber was rotated in order to generate a continuous swirl having the flow field of a solid body rotation, resulting in the linear dependance of the swirl number on the rotating speed of the chamber. Emulsified fuel is injected into the chamber and the developing process of fuel sprays is visualized. The fuel spray developing process in D.I. diesel engine was investigated by this liquid injection technique. The effect of swirl on the spray tip penetration is quantified through modelling. Results show that the spray tip penetration is qualitatively different for low and high pressure injections. For high pressure injection case, a good agreement is achieved between the experimental results and the modeling accounting the effect of swirl. For low pressure injection, a reasonable agreement is obtained. It is found that excessive swirl may cause adverse effect on spray dispersion during the initial combustion period since the spray can not be impinged on chamber wall.

• Transactions of the Korean Society of Automotive Engineers
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• v.21 no.5
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• pp.169-175
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• 2013

CRDi technology of diesel engine was developed from in the early 2000s due to a need to increase fuel efficiency and environment care. Especially, high-pressure fuel injection system in CRDi system which has a fuel injection unit including an injector, a fuel pump and common-rail, etc. becomes possible to make the exhaust gas clean as well as power improvement. In this study, comparison of dynamic characteristics of servo-hydraulic piezo-driven injector with 3-way and bypass-circuit type was analyzed by using the AMESim code. As results of this study, it found the bypass-circuit inside servo-hydraulic piezo injector can cause a faster injection response than that of the 3-way type. Also it was shown that bypass-circuit type had better control capability due to hydraulic bypass system.

• Journal of the Korean Society of Propulsion Engineers
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• v.10 no.1
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• pp.23-29
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• 2006

In an annular injection supersonic ejector, the supersonic primary flow is injected along the side wall, therefore a funnel-shaped shock wave is generated by the contraction angle of the mixing chamber. In the present study, we developed a simple funnel shock wave model using 2-D wedge and conical shock wave relations. In result, the secondary flow pressure can be predicted more accurately than using a simple 2-D wedge shock wave model. Through the same analysis, the compression ratio and the adiabatic efficiency according to the entrainment ratio were calculated.