• Title/Summary/Keyword: Initiatives

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Urban Informatics: Using Big Data for City Scale Analytics

  • Koo, Bonsang;Shin, Byungjin
    • International conference on construction engineering and project management
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    • 2015.10a
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    • pp.41-43
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    • 2015
  • Urban Informatics, the application of data science methodologies to the urban development and planning domain, has been increasingly adopted to improve the management and efficiency of cities. This paper introduces state of the art use cases in major cities including New York, London, Seoul and Amsterdam. It also introduces recent advances in using Big Data by multi-lateral institutions for poverty reduction, and startups utilizing open data initiatives to create new value and insights. Preliminary research performed on using Seoul's open data such as building permit data and health code violations are also introduced to demonstrate opportunities in this relatively new but promising area of research.

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Study on Typologies and Methodologies of Civic Engagement Projects - Focused on Yokohama Shimin Machi-bushin Project in Japan - (주민참여공모사업의 사업유형과 의견분석방법에 관한 연구 - 일본 요코하마 주민공모사업을 대상으로 -)

  • Han, Changhee
    • Journal of the Korean Institute of Rural Architecture
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    • v.26 no.1
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    • pp.41-49
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    • 2024
  • This study focuses on citizen-driven regional agenda and improvement projects, with a specific emphasis on the Yokohama Shimin Machi-bushin Project. The research aims to categorize the scope of citizens' thoughts and the objects for improvement, shedding light on the Analysis Methodologies of citizen-driven proposals for living environment improvement. It also highlights the diverse factors influencing citizens' perceptions of regional issues and the different approaches to addressing them. The paper discusses potential challenges and obstacles in implementing citizen-driven initiatives for community improvement and suggests ways to address them effectively. Overall, the study underscores the significance of citizen participation in community development and the need to understand their perspectives and thought processes in proposing and implementing community improvement initiatives.

Structural Design Optimization of Dynamic Crack Propagation Problems Using Peridynamics (페리다이나믹스를 이용한 균열진전 문제의 구조 최적설계)

  • Kim, Jae-Hyun;Park, Soomin;Cho, Seonho
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.28 no.4
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    • pp.425-431
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    • 2015
  • Based on a bond-based peridynamics theory for dynamic crack propagation problems, this paper presents a design sensitivity analysis and optimization method. Peridynamics has a peculiar advantage over the existing continuum theory in the mathematical modelling of problems where discontinuities arise. For the design optimization of the crack propagation problems, a non-shape design sensitivity is derived using the adjoint variable method. The obtained adjoint sensitivity of displacement and strain energy turns out to be very accurate and efficient compared to the finite different sensitivity. The obtained design sensitivities are futher utilized to optimally control the position of bifurcation point in the design optimization of crack propagation in a plate under tension. A numerical experiment demonstrates that the optimal distribution of material density could delay the position of bifurcation.

WWC1 and NF2 Prevent the Development of Intrahepatic Cholangiocarcinoma by Regulating YAP/TAZ Activity through LATS in Mice

  • Park, Jaeoh;Kim, Jeong Sik;Nahm, Ji Hae;Kim, Sang-Kyum;Lee, Da-Hye;Lim, Dae-Sik
    • Molecules and Cells
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    • v.43 no.5
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    • pp.491-499
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    • 2020
  • Hippo signaling acts as a tumor suppressor pathway by inhibiting the proliferation of adult stem cells and progenitor cells in various organs. Liver-specific deletion of Hippo pathway components in mice induces liver cancer development through activation of the transcriptional coactivators, YAP and TAZ, which exhibit nuclear enrichment and are activated in numerous types of cancer. The upstream-most regulators of Warts, the Drosophila ortholog of mammalian LATS1/2, are Kibra, Expanded, and Merlin. However, the roles of the corresponding mammalian orthologs, WWC1, FRMD6 and NF2, in the regulation of LATS1/2 activity and liver tumorigenesis in vivo are not fully understood. Here, we show that deletion of both Wwc1 and Nf2 in the liver accelerates intrahepatic cholangiocarcinoma (iCCA) development through activation of YAP/TAZ. Additionally, biliary epithelial cell-specific deletion of both Lats1 and Lats2 using a Sox9-CreERT2 system resulted in iCCA development through hyperactivation of YAP/TAZ. These findings suggest that WWC1 and NF2 cooperate to promote suppression of cholangiocarcinoma development by inhibiting the oncogenic activity of YAP/TAZ via LATS1/2.

Policy Initiatives to Establish a National Nuclear Education & Training System (국가 차원의 원자력 교육훈련체계 구축을 위한 정책 구상)

  • Ko, Kyungmin;Park, Min-Cheol;Park, Jae-Woo
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.12 no.4
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    • pp.253-265
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    • 2014
  • Nuclear education & training is an important issue for sustainability of nuclear energy and the safety of the nuclear power plant. The purpose of this paper is to present policy initiatives for establishment of the national nuclear education & training system. It analyzed current status of nuclear manpower and nuclear education & training systems of Korean nuclear organizations and government strategic plans for nuclear manpower education & training. The features of the current nuclear education & training in Korea are institutional diversification and decentralization in Industry-University-Research system. However, linkages and cooperation systematically integrated between institutions are very weak. In addition, duplicated education & training programs and resource allocation, and the resultant inefficiency have been raised as a problem. Therefore, this paper proposed the national nuclear education & training system model as a macro policy initiatives and construction of control tower that manage and adjust overall nuclear education & training.

Dentists' Perception of the Role they Play in Early Detection of Oral Cancer

  • Saleh, Amyza;Kong, Yink Heay;Vengu, Nedunchelian;Badrudeen, Haja;Zain, Rosnah Binti;Cheong, Sok Ching
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.229-237
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    • 2014
  • Background: Dentists are typically the first professionals who are approached to treat ailments within the oral cavity. Therefore they should be well-equipped in detecting suspicious lesions during routine clinical practice. This study determined the levels of knowledge on early signs and risk factors associated with oral cancer and identified which factors influenced dentist participation in prevention and early detection of oral cancer. Materials and Methods: A survey on dentists' knowledge and their practices in prevention and early detection of oral cancer was conducted using a 26-item self-administered questionnaire. Results and Conclusions: A response rate of 41.7% was achieved. The level of knowledge on early signs and risk habits associated with oral cancer was high and the majority reported to have conducted opportunistic screening and advised patients on risk habit cessation. Factors that influenced the dentist in practising prevention and early detection of oral cancer were continuous education on oral cancer, age, nature of practice and recent graduation. Notably, dentists were receptive to further training in the area of oral cancer detection and cessation of risk habits. Taken together, the study demonstrated that the dental clinic is a good avenue to conduct programs on opportunistic screening, and continuous education in these areas is necessary to adequately equip dentists in running these programs. Further, this study also highlighted knowledge deficits and practice shortcomings which will help in planning and developing programs that further encourage better participation of dentists in prevention and early detection of oral cancer.

Experimental Validation of Topology Design Optimization (밀도법 기반 위상 최적설계의 실험적 검증)

  • Cha, Song-Hyun;Lee, Seung-Wook;Cho, Seonho
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.26 no.4
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    • pp.241-246
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    • 2013
  • From the numerical results of density-based topology design optimization, a CAD geometric model is constructed and fabricated using 3D printer to experimentally validate the optimal design. In the process of topology design optimization, we often experience checkerboard phenomenon and complicated branches, which could result in the manufacturing difficulty of the obtained optimal design. Sensitivity filtering and morphology methods are used to resolve the aforementioned issues. Identical volume fraction is used in both numerical and experimental models for precise validation. Through the experimental comparison of stiffness in various designs including the optimal design, it turns out that the optimal design has the highest stiffness and the experimental result of compliance matches very well with the numerical one.

An Estimation on Development Capacity under Urban Growth Management Policies: A Case of Maryland in the U.S. (도시성장관리정책 하에서의 개발용량 추정과 정책적 함의: 미국 매릴랜드 주를 사례로)

  • Sohn, Jung-Yul;Knaap, Gerrit
    • Journal of the Korean Geographical Society
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    • v.43 no.1
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    • pp.52-70
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    • 2008
  • Using MD Property View database on 15 counties in Maryland in the U.S., this study attempts to explore the estimation process on the housing development capacity under the Maryland's urban growth management policy known as the Smart Growth Initiatives. This study also seeks to draw the implications of the estimated development capacity by individual counties on successful implementation of the urban growth management policy. The finding shows that this region has land for residential use enough to accommodate growth for the next 30 years. However, contrary to the goal of the Smart Growth Initiatives, a majority of development capacity is located not only outside the Priority Funding Area designated by the Smart Growth Initiatives but also at counties that are located far away from the major metropolitan area. In addressing this problem, the state does not need to either abolish or immediately expand the Priority Funding Area. Rather, the state requires local governments to include housing elements in their comprehensive planning, to provide periodic estimates on housing and employment capacity, and to establish and manage database on the location and the capacity of developable land.