• Title/Summary/Keyword: Initiative

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An Evaluation of the Collaborative Urban Environment Improvement Initiative in South Korea: A Case Study of Demolishing Walls Initiative in Daegu City (한국의 공동체 도시환경 개선사업 평가: 대구광역시 담장허물기사업을 사례로)

  • Kim Soobong
    • Journal of Environmental Science International
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    • v.13 no.10
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    • pp.863-870
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    • 2004
  • The main objectives of this research are to analyse and evaluate the demolishing walls initiative in Daegu city as the collaborative urban environment improvement initiative in South Korea using the actor network theory concept. Local authorities are unable to effectively and efficiently improve urban environment because of their limited statutory and financial powers. This inability crucially led to the formation of the demolishing walls initiative in Daegu city with building a coalition of the local people, interest groups and public and non-governmental organisations in the operational processes in order to improve the physical and social urban environments. Furthermore, co-ordination between local authorities and landscape architecture specialists not only to change the way in which they tackle urban environmental problems but also to make the local people aware of their potential ability in positively improving the urban environment.

An Induction Scheme of Fast Initiative-Evacuation Based on Social Graphs

  • Taiyo, Ichinose;Tomoya, Kawakami
    • Journal of Information Processing Systems
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    • v.18 no.6
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    • pp.770-783
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    • 2022
  • Early evacuations reduce the damage caused by catastrophic events such as terrorism, tsunamis, heavy rains, landslides, and river floods. However, even when warnings are issued, people do not easily evacuate during these events. To shorten the evacuation time, initiative-evacuation and its executors, initiative evacuees, are crucial in inducing other evacuations. The initiative evacuees take the initiative in evacuating and call out to their surroundings. This paper proposes a fast method to induce initiative-evacuation based on social graphs. The candidates are determined in descending order of the number of links for each person. The proposed method was evaluated through simulations. The simulation results showed a significant reduction in evacuation time.

Guidelines for Manufacturing and Application of Organoids: Brain

  • Taehwan Kwak;Si-Hyung Park;Siyoung Lee;Yujeong Shin;Ki-Jun Yoon;Seung-Woo Cho;Jong-Chan Park;Seung-Ho Yang;Heeyeong Cho;Heh-In Im;Sun-Ju Ahn;Woong Sun;Ji Hun Yang
    • International Journal of Stem Cells
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    • v.17 no.2
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    • pp.158-181
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    • 2024
  • This study offers a comprehensive overview of brain organoids for researchers. It combines expert opinions with technical summaries on organoid definitions, characteristics, culture methods, and quality control. This approach aims to enhance the utilization of brain organoids in research. Brain organoids, as three-dimensional human cell models mimicking the nervous system, hold immense promise for studying the human brain. They offer advantages over traditional methods, replicating anatomical structures, physiological features, and complex neuronal networks. Additionally, brain organoids can model nervous system development and interactions between cell types and the microenvironment. By providing a foundation for utilizing the most human-relevant tissue models, this work empowers researchers to overcome limitations of two-dimensional cultures and conduct advanced disease modeling research.

Guidelines for Manufacturing and Application of Organoids: Heart

  • Hyang-Ae Lee;Dong-Hun Woo;Do-Sun Lim;Jisun Oh;C-Yoon Kim;Ok-Nam Bae;Sun-Ju Ahn
    • International Journal of Stem Cells
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    • v.17 no.2
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    • pp.130-140
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    • 2024
  • Cardiac organoids have emerged as invaluable tools for assessing the impact of diverse substances on heart function. This report introduces guidelines for general requirements for manufacturing cardiac organoids and conducting cardiac organoid-based assays, encompassing protocols, analytical methodologies, and ethical considerations. In the quest to employ recently developed three-dimensional cardiac organoid models as substitutes for animal testing, it becomes imperative to establish robust criteria for evaluating organoid quality and conducting toxicity assessments. This guideline addresses this need, catering to regulatory requirements, and describes common standards for organoid quality and toxicity assessment methodologies, commensurate with current technological capabilities. While acknowledging the dynamic nature of technological progress and the potential for future comparative studies, this guideline serves as a foundational framework. It offers a comprehensive approach to standardized cardiac organoid testing, ensuring scientific rigor, reproducibility, and ethical integrity in investigations of cardiotoxicity, particularly through the utilization of human pluripotent stem cell-derived cardiac organoids.