• Food Science of Animal Resources
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• v.37 no.4
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• pp.579-592
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• 2017

This study assessed the quantitative microbial risk of non-enterohemorrhagic Escherichia coli (EHEC). For hazard identification, hazards of non-EHEC E. coli in natural and processed cheeses were identified by research papers. Regarding exposure assessment, non-EHEC E. coli cell counts in cheese were enumerated, and the developed predictive models were used to describe the fates of non-EHEC E. coli strains in cheese during distribution and storage. In addition, data on the amounts and frequency of cheese consumption were collected from the research report of the Ministry of Food and Drug Safety. For hazard characterization, a doseresponse model for non-EHEC E. coli was used. Using the collected data, simulation models were constructed, using software @RISK to calculate the risk of illness per person per day. Non-EHEC E. coli cells in natural- (n=90) and processed-cheese samples (n=308) from factories and markets were not detected. Thus, we estimated the initial levels of contamination by Uniform distribution ${\times}$ Beta distribution, and the levels were -2.35 and -2.73 Log CFU/g for natural and processed cheese, respectively. The proposed predictive models described properly the fates of non-EHEC E. coli during distribution and storage of cheese. For hazard characterization, we used the Beta-Poisson model (${\alpha}=2.21{\times}10^{-1}$, $N_{50}=6.85{\times}10^7$). The results of risk characterization for non-EHEC E. coli in natural and processed cheese were $1.36{\times}10^{-7}$ and $2.12{\times}10^{-10}$ (the mean probability of illness per person per day), respectively. These results indicate that the risk of non-EHEC E. coli foodborne illness can be considered low in present conditions.

• Journal of the Society of Naval Architects of Korea
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• v.57 no.1
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• pp.1-7
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• 2020

In general, an inspection schedule is established based on the long-term fatigue life during the design stage. However, in the design stage, it is difficult to clearly identify the uncertainty factors affecting long-term fatigue life. In this study, the probabilistic fatigue life assessment was conducted in accordance with the methodology of DNV-GL. Firstly, The initial crack distribution estimated through the initial crack propagation analysis was updated by reflecting the results of crack inspection. Secondly, the updated crack distribution was compared with the initial crack distribution, and the probability of failure was updated with the effect of crack inspection.

• Journal of Environmental Health Sciences
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• v.43 no.3
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• pp.194-201
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• 2017

Objectives: Zinc oxide nanoparticles (ZnO NPs) are widely used in various commercial products, but they are exposed to the environment and can induce toxicity. In this study, we investigated the environmental fate and bioaccumulation of ZnO NPs in a microcosm. Methods: The microcosm was composed of water, soil (Lufa Soil 2.2) and organisms (Oryzias latipes, Neocaridina denticulata, Semisulcospira libertina). Point five and 5 mg/L of ZnO NPs were exposed in the microcosm for 14 days. Total Zn concentrations were measured using an Inductively Coupled Plasma Mass Spectrometer (ICP-MS) and intracellular NPs were observed using Transmission Electron Microscopy (TEM). Results: In the initial stages of exposure, the Zn concentrations in water increased in all exposure groups and then decreased, while the Zn concentration in soil increased after three hours for the 5 mg/L solution. Zn concentrations also showed increasing trends in N. denticulata and S. libertina at 0.5 and 5 mg/L, and in O. latipes at 5 mg/L. Accumulation of NPs was found in the livers of O. latipes and hepatopancreas of N. denticulata and S. libertina. Conclusions: In the early stages of exposure, ZnO NPs remained in the water, and then were transported to the soil and test species. Unlike other species, total Zn concentrations in N. denticulata and S. libertina increased for both 0.5 mg/L and 5 mg/L. Therefore, ZnO NPs were more easily accumulated in zoobenthos than in fish.

• Journal of the Korean Society of Safety
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• v.37 no.2
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• pp.1-9
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• 2022

Most factories deal with toxic or flammable chemicals in their industrial processes. These hazardous substances pose a risk of leakage due to accidents, such as fire and explosion. In the event of chemical release, massive casualties and property damage can result; hence, quantitative risk prediction and assessment are necessary. Several methods are available for evaluating chemical dispersion in the atmosphere, and most analyses are considered neutral in dispersion models and under far-field wind condition. The foregoing assumption renders a model valid only after a considerable time has elapsed from the moment chemicals are released or dispersed from a source. Hence, an initial dispersion model is required to assess risk quantitatively and predict the extent of damage because the most dangerous locations are those near a leak source. In this study, the dispersion model for initial consequence analysis was developed with three-dimensional unsteady advective diffusion equation. In this expression, instantaneous leakage is assumed as a puff, and wind velocity is considered as a coordinate transform in the solution. To minimize the buoyant force, ethane is used as leaked fuel, and two different diffusion coefficients are introduced. The calculated concentration field with a molecular diffusion coefficient shows a moving circular iso-line in the horizontal plane. The maximum concentration decreases as time progresses and distance increases. In the case of using a coefficient for turbulent diffusion, the dispersion along the wind velocity direction is enhanced, and an elliptic iso-contour line is found. The result yielded by a widely used commercial program, ALOHA, was compared with the end point of the lower explosion limit. In the future, we plan to build a more accurate and general initial risk assessment model by considering the turbulence diffusion and buoyancy effect on dispersion.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2018.05a
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• pp.162-163
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• 2018

A risk assessment is performed at the initial design stage of LNG-fuelled ships subject to new fuel supply systems due to marine environmental and emissions regulations. Risk assessment involves a series of logical steps that enable systematic risk analysis and evaluation. LNG-fuelled ships mainly consist of a tank for storing LNG, a gas supply unit for supplying LNG to the engine, an engine using LNG as fuel, and a bunkering manifold for receiving LNG. The components of the LNG fuelled ship are determined according to the characteristics, size, rout, and operating distance. Therefore, the risk factors of each ships are different, and the risk analysis also changes. In this study we consider the systems of ships using LNG as a fuel and analyze the risk assessment of certain cases where the actual risk assessment has been carried out.

• Toxicological Research
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• v.21 no.4
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• pp.297-301
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• 2005

Farmers are generally expressed to pesticides through mixing loding, application activity and harvesting of crop after application of pesticides. The present work investigated the exposure and risk of furathiocarb to workers when harvesting of cucumber was carried out in green house after application of furathiocarb EC. Glove was used for the hand exposure assessment, socks for foot and dermal patches for the other parts of body. Personal air monitor equipped with a XAD-2 resin was used for the respiratory exposure assessment. During the harvest of cucumber in green house, the initial rate of potential dermal exposure (Day 1) for methidathion was 1.3 mg/hr. The major exposure parts were hand $(78\~83\%),\;thigh\;(5\~7\%)$ and arms $(6\~9\%)$ during 3 days' harvest. No exposure was detected from the respiratory monitoring. For risk assessment, the potential dermal exposure (PDE), the absorbable quantity of exposure (AQE) and the margin of safety (MOS) and margin of exposure (MOE) were calculated. In risk assessment of harvester exposure for 7days, all MOS was > 1 and MOE was > 100 indicating that possibility of risk was little.

• Journal of Convergence for Information Technology
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• v.9 no.6
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• pp.175-182
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• 2019

This study was conducted to test the assessment validity and examine the cut-off scores for driving risk as a part of the Self-report Assessment Forecasting Elderly Driving Risk (SAFE-DR) development project. The 132 senior drivers were categorized as either risky of 58 or safe of 74 drivers through the Drivers 65 Plus. Based on this initial assessment, we analyzed the risk prediction cut-offs. Furthermore, we tested the construct, content, and predictive validity. The cut-off score for the prediction of driving risk was found to be 74.5 points. The positive predictive value was 88.6%, and the negative predictive value was 86.3% about the cut-off score, signifying an excellent level of discrimination. Convergent validity, nomological validity, and content validity were found to be appropriate. Therefore, this study confirms that SAFE-DR is an appropriate assessment that can be used to screen dangerous elderly drivers.

• Journal of the Korean Society of Safety
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• v.31 no.6
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• pp.93-98
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• 2016

This study analyzed the inflow characteristics of debris flow according to shape of defensive structure and computed risk index. In order to simulate debris flow, two shapes of defensive structure were considered. Initial mass distribution was set with a rectangular shape and defensive structures were set semi-circular shape and rectangular shape, respectively. It was found that a defensive structure with semicircular shape was more vulnerable to debris impact compared with rectangular shape because the flow mass became concentrated in quadrant part of the inner circle. If the velocity of the debris flow was less than 1 m/s, the risk assessment by FII (Flood Intensity Index) was much appropriate. However, when the movement of debris runout was faster than 1 m/s, the risk index of FHR (Flood Hazard Rating) provided improved classification due to its subdivided hazardous range.

• Food Science of Animal Resources
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• v.35 no.5
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• pp.674-682
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• 2015

The objective of this study was to evaluate the risk of illness from Campylobacter spp. on ham. To identify the hazards of Campylobacter spp. on ham, the general characteristics and microbial criteria for Campylobacter spp., and campylobacteriosis outbreaks were investigated. In the exposure assessment, the prevalence of Campylobacter spp. on ham was evaluated, and the probabilistic distributions for the temperature of ham surfaces in retail markets and home refrigerators were prepared. In addition, the raw data from the Korea National Health and Nutrition Examination Survey (KNHNES) 2012 were used to estimate the consumption amount and frequency of ham. In the hazard characterization, the Beta-Poisson model for Campylobacter spp. infection was used. For risk characterization, a simulation model was developed using the collected data, and the risk of Campylobacter spp. on ham was estimated with @RISK. The Campylobacter spp. cell counts on ham samples were below the detection limit (<0.70 Log CFU/g). The daily consumption of ham was 23.93 g per person, and the consumption frequency was 11.57%. The simulated mean value of the initial contamination level of Campylobacter spp. on ham was −3.95 Log CFU/g, and the mean value of ham for probable risk per person per day was 2.20×10⁻¹². It is considered that the risk of foodborne illness for Campylobacter spp. was low. Furthermore, these results indicate that the microbial risk assessment of Campylobacter spp. in this study should be useful in providing scientific evidence to set up the criteria of Campylobacter spp..

• Journal of Korean Neurosurgical Society
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• v.45 no.2
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• pp.90-95
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• 2009

Objective : We aimed to identify clinico-radiological risk factors that may predict unfavorable neurological outcomes in traumatic brain injury (TBI), and to establish a guideline for patient selection in clinical trials that would improve neurological outcome during the early post TBI period. Methods : Initial clinico-radiological data of 115 TBI patients were collected prospectively. Regular neurological assessment after standard treatment divided the above patients into 2 groups after 6 months : the Favorable neurological outcome group (GOS : good & moderate disability, DRS : 0-6, LCFS : 8-10) and the Unfavorable group (GOS : severe disability-death, DRS : 7-29 and death, LCFS : 1-7 and death). Results : There was a higher incidence of age $\geq$35 years, low initial GCS score, at least unilateral pupil dilatation, and neurological deficit in the Unfavorable group. The presence of bilateral parenchymal lesions or lesions involving the midline structures in the initial brain CT was observed to be a radiological risk factor for unfavorable outcome. Multivariate analysis demonstrated that age and initial GCS score were independent risk factors. The majority of the Favorable group patients with at least one or more risk factors showed improvement of GCS scores within 2 months after TBI. Conclusion : Patients with the above mentioned clinico-radiological risk factors who received standard treatment, but did not demonstrate neurological improvement within 2 months after TBI were deemed at risk for unfavorable outcome. These patients may be eligible candidates for clinical trials that would improve functional outcome after TBI.