• 제목/요약/키워드: Initial risk assessment

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Development of genetically modified crops based on considerations of risk assessment and management (위해성평가와 관리를 고려한 유전자변형작물 개발의 필요성)

  • Kim, Chang-Gi;Jeong, Soon-Chun;Yoon, Won-Kee;Park, Kee-Woong;Choi, Kyung-Hwa;Kim, Hwan-Mook
    • Journal of Plant Biotechnology
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    • v.36 no.4
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    • pp.360-365
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    • 2009
  • Over the last five years, we have conducted research on risk assessment of domestically developed genetically modified (GM) crops and found a number of factors which could delay risk assessment process. In this review, we described such cases and discussed the problem of transgene cassette integration, the lack of information on vectors, the poor quality control in seed production and absence of bioinformatic analysis on amino acid sequence homology before GM crop development. To solve these problems, we have suggested the introduction of the screening system of elite event before risk assessment process and quality control strategies for GM seed production. In addition, we suggested that the developers of GM crops should understand the importance of risk assessment and management for the commercialization of those crops and consider the biological and ecological characteristics of host plants. Consistent communications may need to be established between GM crop developers, risk assessors and risk managers at the initial stages of GM crop development to reduce trial-and-errors.

Insights from existing earthquake loss assessment research in Croatia

  • Hadzima-Nyarko, Marijana;Sipos, Tanja Kalman
    • Earthquakes and Structures
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    • v.13 no.4
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    • pp.365-375
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    • 2017
  • Seismic risk management has two main technical aspects: to recommend the construction of high-performance buildings and other structures using earthquake-resistant designs or evaluate existing ones, and to prepare emergency plans using realistic seismic scenarios. An overview of seismic risk assessment methodologies in Croatia is provided with details regarding the components of the assessment procedures: hazard, vulnerability and exposure. For Croatia, hazard is presented with two maps and it is expressed in terms of the peak horizontal ground acceleration during an earthquake, with the return period of 95 or 475 years. A standard building typology catalogue for Croatia has not been prepared yet, but a database for the fourth largest city in Croatia is currently in its initial stage. Two methods for earthquake vulnerability assessment are applied and compared. The first is a relatively simple and fast analysis of potential seismic vulnerability proposed by Croatian researchers using damage index (DI) as a numerical value indicating the level of structural damage, while the second is the Macroseismic method.

Environmental Risk Assessment for Ivermectin, Praziquantel, Tamiflu and Triclosan (Ivermectin, praziquantel, tamiflu, triclosan의 환경위해성평가)

  • Ryu, Taekwon;Kim, Jungkon;Kim, Kyungtae;Lee, Jaewoo;Kim, Jieun;Cho, Jaegu;Yoon, Junheon;Lee, Jaean;Kim, Pilje;Ryu, Jisung
    • Journal of Environmental Health Sciences
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    • v.44 no.2
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    • pp.196-203
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    • 2018
  • Objectives: The purpose of this study was to assess environmental risk on the emerging contaminants of concern, such as ivermetin, parziquantel, tamiflu and triclosan. Furthermore, we tried to provide a more efficient management practice and a basis for future studies of risk assessment on those substances. Methods: Predicted no effect concentration (PNEC) and predicted environmental concentration (PEC) were determined through modeling and literature reviews. Environmental risk assessment was evaluated by calculating HQ (hazard quotient) by a comparison of PEC (or measured environmental concentration (MEC)) and PNEC. Results: HQ value of tamiflu calculated from MEC was 1.9E-03. For ivermectin and triclosan, the HQ values were not available because these were not detected in the aquatic environment. The toxicity of ivermectin and triclosan showed a very low value, indicating a high level of HQ. However, praziquantel can be categorized into the material that do not require management since they have less than HQ 1. Conclusion: Based on the results of the initial risk assessment, it is assumed that the ivermectin and triclosan have potential to cause direct adverse effects on the aquatic environment. To conduct an accurate environmental risk assessment, the further study on PEC estimation of such contaminants should be actively carried out.

A Study on the Risk Assessment of Small Reservoirs using Reliability Analysis Methods (신뢰도 분석기법을 이용한 소규모 저수지의 위험도 분석)

  • Kim, Mun-Mo;Park, Chang-Eon
    • Journal of Korea Water Resources Association
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    • v.33 no.1
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    • pp.15-30
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    • 2000
  • This study is to develop the applied method of reliability analysis to present risk - initial water level relationship in the small reservoir. To determine the reliability, the grasping of uncertainty sources is prerequisited and performance function is formulated. Reliability analysis method is a statistical method and the basic procedure of risk evaluation for overtopping of reservoir is as follows. 1. Define the risk criterion and performance function for the overtopping. 2. Determine the uncertainties of all the variables in the performance function. 3. Perform the risk analysis with suitable risk calculation method. Reliability analysis method such as Monte Carlo simulation(MCS) method and mean value first order second moment(MVFOSM) method are used to calculate the risk for reservoir. Finally, risk - initial water level relationship is established according to return period and it is useful for reservoir operation and safety assessment.ssment.

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Application of JSA and Checklist in Asbestos Sealing (석면 해체제거 보양작업에서 JSA 및 Checklist 적용)

  • Cho, Guy Sun
    • Journal of the Korean Society of Safety
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    • v.35 no.2
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    • pp.61-66
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    • 2020
  • As asbestos-containing buildings are getting older, asbestos deconstruction works are increasing. As a result, accident risks such as falls, cuts, electric shocks, and suffocation are increasing. Existing studies are mostly about health management and institutional policy research and there is little research on work risk. So workplace risk assessments that are easily applicable in the field are required to be applied. Sealing is the first process of asbestos deconstruction and is the first step to ensure worker's safety. Job Safety Analysis(JSA) and Checklist were used to identify the risk factors and to calculate the level of the risk. By comparing the two risk assessment tools, it was figured out that the JSA is appropriate for the initial process and change of work procedure while Checklist is appropriate for repetitive work. Because the sealing process is sort and simple, it is unlikely to cause serious injury. But since the risk of falling and cuts are exist, safety education and supervision are necessary to maintain a safe working environment.

Decision Making of Seismic Performance Management Using Seismic Risk Assessment (지진위험도평가 방법을 이용한 내진성능관리 의사결정)

  • Kim, Dong Joo;Choi, Ji Hye;Kim, Byeong Hwa
    • Journal of the Earthquake Engineering Society of Korea
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    • v.23 no.6
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    • pp.329-339
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    • 2019
  • The strategy for the management of earthquakes is shifting from post recovery to prevention; therefore, seismic performance management requires quantitative predictions of damage and the establishment of strategies for initial responses to earthquakes. Currently, seismic performance evaluation for seismic management in Korea consists of two stages: preliminary evaluation and detailed evaluation. Also, the priority of seismic performance management is determined in accordance with the preliminary evaluation. As a deterministic method, preliminary evaluation quantifies the physical condition and socio-economic importance of a facility by various predetermined indices, and the priority is decided by the relative value of the indices; however, with the deterministic method it is difficult to consider any uncertainty related to the return-year, epicenter, and propagation of seismic energy. Also this method cannot support tasks such as quantitative socio-economic damage and the provision of data for initial responses to earthquakes. Moreover, indirect damage is often greater than direct damage; therefore, a method to quantify damage is needed to enhance accuracy. In this paper, a Seismic Risk Assessment is used to quantify the cost of damage of road facilities in Pohang city and to support decision making.

RISK FRAMEWORK FOR NEXT GENERATION NUCLEAR POWER PLANT CONSTRUCTION

  • John Walewski ;Stuart Anderson;Jaeheum Yeon;Amy Kim
    • International conference on construction engineering and project management
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    • 2013.01a
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    • pp.451-458
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    • 2013
  • This research documents the initial findings and recommendations for developing a risk management tool to assess and quantify the risks associated with the construction of the next generation of nuclear power plants. The proposed tool builds upon the Construction Industry Institute's International Project Risk Assessment (IPRA) Best Practice. This paper provides an overview of the investigation to assess the unique risk elements pertaining to nuclear power plant construction and documents the preliminary findings from historical project performance data to better understand the function and use of the IPRA's Relative Impact value.

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Comparison of Clinical Characteristics and Prognosis by Initial Endoscopic Severity in Caustic Injury (부식제 음독 환자에서 초기 내시경 소견의 중증도에 따른 임상 소견 및 예후 비교)

  • Lee, Sang Min;Choi, Woo Ik;Kim, Sung Jin;Jin, Sang Chan
    • Journal of The Korean Society of Clinical Toxicology
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    • v.13 no.2
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    • pp.87-94
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    • 2015
  • Purpose: We investigated comparison of clinical characteristics and prognosis by initial endoscopic severity in caustic injury and then discussed predisposing factors which can be helpful in predicting the prognosis and determining the treatment. Methods: This study was a retrospective review of medical records from patients over the age of 15, who underwent initial endoscopy for caustic injury from April 2007 through November 2014. Patients were classified according to two groups based on the initial endoscopic finding by Zargar's classification: patients with grade 0, I, IIa at esophagus (low risk group) and patients with grade IIb, IIIa, IIIb at esophagus (high risk group). The two groups were then compared. Results: A total of 55 patients were included (low risk group [n=44] vs. high risk group [n=11]). Old age (p<0.001), large amount of ingestion (p<0.05), oropharyngeal symptoms (p<0.01), high SOFA score (p<0.001), high WBC count (p<0.05), low base excess (p<0.01), and HCO3 (p<0.05) were statistically significant factors in the high risk group. A poor prognosis was observed for hospital stay (p<0.001), ICU admission (p<0.001), mortality (p<0.01), and stricture (p<0.001) in the high risk group. Conclusion: Clinical characteristics including age, amount of ingestion, oropharyngeal symptoms, SOFA score, WBC count, base excess, and $HCO_3$ can be helpful in the decision to undergo initial endoscopy and risk assessment by initial endoscopic severity can be helpful in predicting prognosis and determining the treatment plan.

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Quantitative microbial risk assessment indicates very low risk for Vibrio parahaemolyticus foodborne illness from Jeotgal in South Korea

  • Choi, Yukyung;Kang, Joohyun;Lee, Yewon;Seo, Yeongeun;Kim, Sejeong;Ha, Jimyeong;Oh, Hyemin;Kim, Yujin;Park, Eunyoung;Lee, Heeyoung;Lee, Soomin;Rhee, Min Suk;Yoon, Yohan
    • Fisheries and Aquatic Sciences
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    • v.25 no.9
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    • pp.463-472
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    • 2022
  • In this study, a microbial risk assessment was performed for the bacteria Vibrio parahaemolyticus, which causes a foodborne illness following the consumption of Jeotgal, a fermented seafood in South Korea. The assessment comprised of six stages: product, market, home, consumption, dose-response, and risk. The initial contamination level (IC) was calculated based on the prevalence of V. parahaemolyticus in 90 Jeotgal samples. The kinetic behavior of V. parahaemolyticus was described using predictive models. The data on transportation conditions from manufacturer to market and home were collected through personal communication and from previous studies. Data for the Jeotgal consumption status were obtained, and an appropriate probability distribution was established. The simulation models responding to the scenario were analyzed using the @RISK program. The IC of V. parahaemolyticus was estimated using beta distribution [Beta (1, 91)]. The cell counts during transportation were estimated using Weibull and polynomial models [δ = 1 / (0.0718 - 0.0097 × T + 0.0005 × T2)], while the probability distributions for time and temperature were estimated using Pert, Weibull, Uniform, and LogLogistic distributions. Daily average consumption amounts were assessed using the Pareto distribution [0.60284,1.32,Risk Truncate(0,155)]. The results indicated that the risk of V. parahaemolyticus infection through Jeotgal consumption is low in South Korea.

Initial Ecological Risk Assessment of 1,2-Benzisothiazol-3-one in Environment (환경 중 1,2-Benzisothiazol-3-one에 대한 초기 생태위해성 평가)

  • Han, Hye-Jin;Kim, EunJu;Yoo, SunKyoung;Ro, Hi-Young;Baek, Yong-Wook;Shim, IlSeob;Eom, Ig-Chun;Kim, Hyun-Mi;Kim, PilJe;Choi, Kyunghee
    • Journal of Korean Society of Environmental Engineers
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    • v.35 no.3
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    • pp.165-170
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    • 2013
  • In this study, physico-chemical properties and environmental fate were investigated and ecotoxicity tests using fish, daphnia and algae were conducted for an initial ecological risk assessment of 1,2-Benzisothiazol-3-one. Due to low volatility of the test substance under environmental conditions, it is likely to distributed in soil and water environment. The compound has low adsorption in the soil, with low bioconcentration potential. Acute toxicity results showed that 96 h-$LC_{50}$ for Oryzias laties was 4.7 mg/L (measured) and 48h-$EC_{50}$ for Daphnia magna was 3.3 mg/L (measured). In a growth inhibition test with Pseudokirchneriella subcapitata, 72 h-$EC_{50}$ was 0.456 mg/L (growth rate, nominal) and 0.262 mg/L (yield, nominal). Using the acute toxicity value of algae, predicted no-effect concentration (PNEC) in the aquatic environment was determined to be 2.62 ${\mu}g/L$ using an factor of 100. According to globally harmonized system (GHS), the compound was categorized as aquatic acute 1 for algae, while it was categorized as aquatic acute 2 for fish and daphnia. This screening assessment suggests that the test substance may pose ecological risks in the aquatic environment.