• Korean Journal of Food Science and Technology
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• v.34 no.4
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• pp.700-709
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• 2002

To develop a natural food preservatives from medicinal herbs (62 species), antimicrobial test was performed with hot water and ethanol extracts against Escherchia coli, Listeria monocytogens and Candida albicans by paper disk method. And its result as a first screening test, 7 kinds of medicinal herbs were selected, and more precise analysis was conducted at last 3 kinds of medicinal herbs was finally selected. Therminalia chebula Retz and Rhus javanica has a broad antimicrobial spectrums and has a low MIC values. In growth inhibition test, they showed a very strong antimicrobial activity aganist Listeria monocytogens. If there has a elaborate approaches in its characteristics and properties, some good result must followed in making a powerful natural antimicrobial preservatives.

• The Korean Journal of Food And Nutrition
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• v.31 no.6
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• pp.926-932
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• 2018

This research was conducted to investigate the changes in quality characteristics of cheonggukjang fermented with the addition of hazelnut (10, 20, 30 and 40%) including; water content, pH, hydrophilic and lipophilic substances, color, viscosity and angiotensin converting enzyme inhibition activity. There was no significant change in pH with the addition of hazelnut. The water content significantly decreased with the addition of hazelnut. Hazelnut was also found to brighten the color of cheonggukjang. L-value and b-value increased with the addition of cheonggjuang. There was an insignificant change in the a-value. There was a slight decrease in the content of hydrophilic with addition of hazelnuts. Where there was more than 20% addition of hazelnut to soybean, the viscous substance content in cheonggukjang decreased significantly. Angiotensin converting enzyme inhibitory activity increased proportionally to the amount of hazelnut added. It was identified that the addition of 40% of hazelnut made its angiotensin converting enzyme inhibitory activity 10% point higher than that of control. These results suggests that the addition of hazelnut makes it possible to produce cheongkukjang of excellent angiotensin converting enzyme inhibitory activity.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.1
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• pp.31-38
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• 2023

Carboplatin, an advanced anticancer drug with excellent efficacy against ovarian cancer, was developed to alleviate the side effects that often occur with cisplatin and other platinum-based compounds. Our study reports the in vitro characteristics, viability, and activity of cells expressing the inducible nitric oxide synthase (iNOS) gene after carboplatin was conjugated with polysuccinimide (PSI) and administered in combination with other widely used anticancer drugs. PSI, which has promising properties as a drug delivery material, could provide a platform for prolonging carboplatin release, regulating its dosage, and improving its side effects. The iNOS gene has been shown to play an important role in both cancer cell survival and inhibition. Herein, we synthesized a PSI-carboplatin conjugate to create a modified anticancer agent and confirmed its successful conjugation. To ensure its solubility in water, we further modified the structure of the PSI-carboplatin conjugate with 2-aminoethanol groups. To validate its biological characteristics, the ovarian cancer cell line SKOV-3 and normal ovarian Chinese hamster ovary cells were treated with the PSI-carboplatin conjugate alone and in combination with paclitaxel and topotecan, both of which are used in conventional chemotherapy. Notably, PSI-carboplatin conjugation can be used to predict changes in the genes involved in cancer growth and inhibition. In conclusion, combination treatment with the newly synthesized polymer-carboplatin conjugate and paclitaxel displayed anticancer activity against ovarian cancer cells but was not toxic to normal ovarian cancer cells, resulting in the development of an effective candidate anticancer drug without severe side effects.

• Journal of Environmental Science International
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• v.23 no.5
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• pp.861-871
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• 2014

This study analyzes the characteristics of ozone weekend effect(OWE) in Busan. $O_3$ concentration on Sunday was over 10% higher than that on weekdays in all areas except for Kwangbokdong, Taejongdae, and Joadong. Such a difference was higher in the industrial area than in the residential area. $O_3$ generation was facilitated by the decrease in $NO_X$ emission on Sunday in VOC-limited regime where the VOC/$NO_X$ ratio is low. Low NO concentration in the Sunday morning decreased inhibition of $O_3$. NO-$O_3$ crossover time on Sunday was shorter than that on weekdays which in turn extended the accumulated duration of $O_3$. Future studies can include whether the entire Busan is VOCS-limited or the coastal area is VOCS-limited while the inland area is $NO_X$-limited.

• Journal of the East Asian Society of Dietary Life
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• v.27 no.2
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• pp.194-203
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• 2017

Mealworm, a type of edible insect, is a superior food material suitable for industrial products. In this study, four different defatted mealworm powders were prepared to determine proper manufacturing conditions. Solvent extraction method reduced lipid contents of mealworms more than pressed mealworms, and lowered lipid contents caused bright colors and good physicochemical properties for powders. In comparison, differences among milling machines used for making powders were strongly related with average size of particles. Meanwhile, the predicted shelf-life of defatted mealworm powders judged by accelerated experiments was 1 year or longer. To enhance shelf-life of mealworm powders, addition of tocopherol to mealworm powders at a concentration of 0.2% could intensify oxidative stability and microbial inhibition.

• Proceedings of the KIEE Conference
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• 1989.07a
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• pp.655-658
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• 1989

The characteristics of proton-diffused $LiNbO_3$ optical waveguides with self-aligned $SiO_2$-cladding are reported. When the proton diffusion occurs, the $SiO_2$-cladding limits the lateral diffusion of protons by out-diffusion of protons in unclad region. Proton indiffusion in depth direction is promoted by inhibition of out-diffusion in clad region. Consequently, the mode profile in depth direction can be nealy symmetric. The extent of the proton exchange was observed by measuring the infrared absorption peak at about $3500cm^{-1}$. It is confirmed that proton diffusion with $SiO_2$-cladding has structural excellency.

• Journal of Korean Society for Atmospheric Environment
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• v.16 no.6
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• pp.665-674
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• 2000

A major source of the hazardous waste generated is from chemical industries producing plastics, herbicides, pesticides and chlorinated solvents. All of these processes produce a class if hazardous waste termed the chlorinated hydrocarbons(CHCs), either directly or from undesirable side reactions. In this study, we investigated the destruction characteristics of hazardous waste through incineration. A nonequilibrium combustion model was used to describe the effect of the chemical kinetics due to the flame inhibition characteristics of $CCl_4$ which was used as the surrogate of hazardous waste. A parametric screening studies was made in a dump incinerator proposed in this study. The dump incinerator showed high $CCl_4$ DRE(Destruction and Removal Efficiency) as 5 nines. $CCl_4$/CH$_4$ ratio appeared to be most important in the destruction of $CCl_4$ through incineration.

• YAKHAK HOEJI
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• v.37 no.4
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• pp.350-355
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• 1993

The preparation of Streptococcus faecalis RSI is used as a medicinal preparation for human intestinal disorders. But the microbe in this preparation is very sensitive to rifampicin. If this preparation is taken with rifampicin, its therapeutic effect can not be expected. To develope rifampicin resistant mutants, the rifampicin sensitive strain S. faecalis RSI was treated with Nmethyl-N'-nitro-N-nitrosoguanidine(MNNG). Twelve strains of the MNNG-induced mutants showed distinct resistance to rifampicin and five mutants were selected for further studies. They also exhibited identical characteristics with the parent S. faecalis RSI when they were tested for lactic acid formation and growth inhibition of E. coli. From in vitro test, it was identified that rifampicin is not inactivated by certain factors of the rifampicin resistant mutants. Conclusively, the rifampicin resistant mutants are efficient strains that have insensitivity against rifampicin and original biochemical characteristics of the parent strain.

• Journal of Korean Society of Water and Wastewater
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• v.11 no.3
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• pp.124-130
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• 1997

Wastewater containing phenol was treated using Pseudomonas sp. B3 in continuous reactor, reaction characteristics and kinetics according to variation of volumetric loading rate in continuous reactor were studied. The removal efficiencies of phenol were more than 99% at the whole range of experiment, and those of COD were 97% at the volumetric loading rate, $0.96kg/m^3{\cdot}d$ and 88% at $3.0kg/m^3{\cdot}d$, respectively. Kinetics constants of $q_m$, $K_s$, Y and $K_d$ were obtained 0.901 l/d, 0.620mg/l, 0.659 and 0.219 l/d, respectively. As compared with to constants of standard activated sludge process, these constants were remarkably different because of toxicity and inhibition of phenol to microbes. And also, kinetics constants of oxygen utilization, a, and b, were shown 0.384 kg $O_2/kg$ phenol and 0.029 l/d.

• Food Science of Animal Resources
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• v.39 no.1
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• pp.35-44
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• 2019

The composition of turmeric powder (TP) can affect the quality properties and storage characteristics of pyeonyuk; however, the appropriate addition level of TP in pyeonyuk has not been established. To address this, an experiment was designed with one control and three TP treatments: control (TP 0%), T1: (TP 0.1%), T2: (TP 0.3%), and T3: (TP 0.5%). All the TP treatments markedly increased protein and ash contents compared to the control. The water holding capacity was equally retained with the control and T3 treatments, but was significantly lower with the T1 and T2 treatments in pyeonyuk (p<0.05). Lightness and redness values were both reduced with the addition of TP, whereas the yellowness value increased. Values for 2-thiobarbituric acid reactive substances and the total microbial count for pyeonyuk with added TP showed an improvement over time. As a result, the addition of TP did not have a significant negative influence on the quality characteristics of the pyeonyuk with addition of 0.5% TP being particularly effective for water retention capacity and inhibition of lipid oxidation.