• 한국의사학회지
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• 제31권1호
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• pp.43-55
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• 2018

This is a review of Juchon (舟村) Sinman's (申曼) book "Juchonsinbang (舟村新方)", describing generations of clinical experience in pediatric practice. Written during King Sukjong era in the middle of the Joseon Dynasty, JuchonSinman used symptoms and general disease terminology, including prescription and treatments employed over generations, so the public could easily utilize the information. "Juchonsinbang (舟村新方)" "pediatric (小兒編)" is characterized by a symptom differentiation method of prescribing herbs which allowed the reader to add or subtract various substances according to symptoms based on Tongchibang (通治方). "Juchonsinbang" includes unique prescriptions and new ways to distinguish acute infantile convulsion (急驚風) according to the cause of fright. Although these prescriptions were not completely new, they present an aspect of an empirical book including JuchonSinman's clinical experience based on existing medical theories. "Juchonsinbang" has a medico-historical value in that it was cited in many medical books such a "Danbangsinpyun (單方新編)", "Sujinggyunghumsinbang (袖珍經驗神方)", and "Hanbang medical pediatric book (漢方醫學小兒全科)" in 1910-30.

• BMB Reports
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• 제45권5호
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• pp.293-298
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• 2012

The p38 mitogen-activated protein kinase (MAPK) is involved in various processes, including stress responses, development, and differentiation. However, little information on p38 MAPK in insects is available. In this study, a p38 MAPK gene, $Accp38b$, was isolated from $Apis$ $cerana$ $cerana$ and characterized. The quantitative real-time PCR (Q-PCR) analysis revealed that $Accp38b$ was induced by multiple stressors. Notably, the expression of $Accp38b$ was relatively higher in the pupae phase than in other developmental phases. During the pupae phase, Accp38b expression was higher in the thorax than in the head and abdomen and higher in the fat body than in the muscle and midgut. Immunohistochemisty showed significant positive staining of Accp38b in sections from the brain, eyes, fat body, and midgut of $A.$ $cerana$ $cerana$. These results suggest that Accp38b may play a crucial role in stress responses and have multiple aspects function during development.

• 생명과학회지
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• 제19권10호
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• pp.1382-1388
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• 2009

Rubus crataegifolius is a shrub species and is primarily distributed throughout Asia and Europe. We collected 550 representative samples of the eleven populations in Korea to estimate leaf variation within species. The 35 morphological characteristics allowed us to resolve well-supported fixed characteristics and variable characteristics. Sixteen of twenty-three quantitative characteristics and five of twelve qualitative characteristics showed significant differences among populations. We argued that the population differentiation can accounted for the variation in phenetic characteristics such as spine in this species, but were less successful in accounting for variation in other traits. Within a polystatistic leaf structure, their morphological differences could be modulated by ecological pressure such as temperature, altitude, duration of sunshine, and solar radiation. The phenogram showed two distinct clades. One was a group in central Korea and the other was a group in the southern regions of Korea. If morphological characteristics in R. crataegifolius populations reflect their ecological niche, morphology should be regarded with caution as the main criterion for population studies in R. crataegifolius.

• Asian-Australasian Journal of Animal Sciences
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• 제15권4호
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• pp.461-465
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• 2002

Nine microsatellite loci were analyzed in 84 random individuals to characterize the genetic variability of three domestic goat breeds found in Korea and China: Korean goat, Chinese goat and Saanen. Allele diversity, heterozygosity, polymorphism information content, F-statistics, indirect estimates of gene flow (Nm) and Nei's standard distances were calculated. Based on the expected mean heterozygosity, the lowest genetic diversity was exhibited in Korean goat ($H_E$=0.381), and the highest in Chinese goat ($H_E$=0.669). After corrections for multiple significance tests, deviations from Hardy-Weinberg equilibrium were statistically significant over all populations and loci, reflecting the deficiencies of heterozygotes (global $F_{IS}$=0.053). Based on pairwise FST and Nm between different breeds, there was a great genetic differentiation between Korean goat and the other two breeds, indicating that these breeds have been genetically subdivided. Similarly, individual clustering based on the proportion of shared alleles showed that Korean goat individuals formed a single cluster separated from the other two goat breeds.

• 동력기계공학회지
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• 제5권4호
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• pp.82-89
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• 2001

To design a structural or a mechanical system with the best performance, the main procedure of a typical design usually consists of repeated modifications of design parameters and the investigation of the system response for each set of these parameters. But this procedure requires much time, effort and experience. Sensitivity analysis can provide systematic information for improving performance of a system. The author has studied on the development of the structural analysis algorithm and suggested recently the transfer stiffness coefficient method(TSCM). This method is very suitable algorithm to a personal computer because the concept of the TSCM is based on the transfer of the nodal stiffness coefficients which are related to force and displacement vectors at each node. In this paper, a new sensitivity analysis algorithm using the concept of the TSCM is formulated for the computation of state variable sensitivity in static problems. The trust of the proposed algorithm is confirmed through the comparison with the computation results using existent sensitivity analysis algorithm and reanalysis for computation models.

• Parasites, Hosts and Diseases
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• 제49권2호
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• pp.103-108
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• 2011

Autophagy is a catabolic process involved in the degradation of a cell's own components for cell growth, development, homeostasis, and the recycling of cellular products. Autophagosome is an essential component in the protozoan parasite during differentiation and encystation. The present study identified and characterized autophagy-related protein (Atg) 3, a member of Atg8 conjugation system, in Acanthamoeba castellanii (AcAtg3). AcAtg3 encoding a 304 amino acid protein showed high similarity with the catalytic cysteine site of other E2 like enzymes of ubiquitin system. Predicted 3D structure of AcAtg3 revealed a hammer-like shape, which is the characteristic structure of E2-like enzymes. The expression level of AcAtg3 did not increase during encystation. However, the formation of mature cysts was significantly reduced in Atg3-siRNA transfected cells in which the production of Atg8-phosphatidylethanolamine conjugate was inhibited. Fluorescent microscopic analysis revealed that dispersed AcAtg3-EGFP fusion protein gathered around autophagosomal membranes during encystation. These results provide important information for understanding autophagic machinery through the lipidation reaction mediated by Atg3 in Acanthamoeba.

• 한국생활과학회지
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• 제20권2호
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• pp.377-389
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• 2011

The object of this study was to analyze the meaning of luxurious consumption, the subjects and the objects of luxurious consumption, the desires that propel luxurious consumption, and the luxurious consumption patterns of the past and the present. The materials and information used for this research were acquired by reviewing literatures from a library. The time frame used to separate the past and the present was the Second World War. The analyzed materials and contents for the research were the subjects and the objects of luxurious consumption, the desires that propel luxurious consumption, and the patterns of luxurious consumption. Comparing the trends of luxurious consumption of the past and present historically, the biggest differentiation between the past and present was the spread of subjects and objects of luxurious consumption. In the past, luxury consumption belonged to the wealthy only, but the accessibility of luxury consumption has increased to the point where anybody can buy what they want at will. Another difference was found in the desires that prompt luxury consumption and the consumption patterns of the past and present. Based on these results, several suggestions about luxury consumption were presented in this paper.

• 한국멀티미디어학회논문지
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• 제17권12호
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• pp.1453-1460
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• 2014

WFQ (Weighted Fair Queuing) provides not only fairness among traffic flows in using bandwidth but also guarantees the Quality of Service (QoS) that individual flow requires, which is why it has been applied to the resource reservation protocol (RSVP)-capable router. The RSVP allocates an enough resource to satisfy both the rate and end-to-end delay requirements of the flow in the condition of no packet loss, and the WFQ scheduler guarantees those QoS requirements with the allocated resource. In practice, however, most QoS-guaranteed services allow a degree of packet loss, especially from 0.1% to 3% for Voice over IP. This paper discovers that the packet loss rate of each traffic flow is determined by only its time-stamp adjustment value, and then enhances the WFQ to provide a differentiated packet loss guarantee under general traffic conditions in terms of both traffic characteristics and QoS requirements. The performance evaluation showed that the proposed WFQ could increase the utilization of bandwidth by 8~11%.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.1155-1157
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• 2013

Cancer is a highly complex medical problem with ramifications for public health throughout the world. Most studies have mainly focused on change in the nuclei as being aetiologically responsible. Few have examined the relationship between the cytoplasm and cancer, despite the fact that research has indicated that the cytoplasmic environment is an important factor for cellular differentiation and that the genetic information provided by the nucleus is entirely dependent on this environment for its expression. Gene mutations may be the result, rather than the cause of carcinogenesis. We submit a new concept - "short base sequences" (50-500 bps, including DNA or RNA sequences) in the cytoplasm which could play an important role in carcinogenesis. This is a new theory to explain the origin of the cancer.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2002년도 International Meeting on Information Display
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• pp.46-49
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• 2002

Recent trends of low-temperature polycrystalline Si (LTPS) TFT technologies are presented. Characteristics of LTPS TFT processes are compared with those of a-Si TFT's. In order to compete with well-established a-Si TFT-LCD technology, LTPS process has to be as simple as possible. One of the most critical processes, recrystallization of a-Si thin films, could be the process for the differentiation of LTPS technology. Along with these technical reviews, a recent development of the 5.0-inch LTPS TFT-LCD is presented. In order to achieve high-performance display characteristics and save the power consumption, the transflective mode is adopted. The 5.0-inch display with 186 pixel-per-inch, high-resolution LCD was measured to be 10% for the reflectance and 70:1 for the contrast ratio. This display is designed for a high information content hand-held PC (HHPC) application.