• 보건행정학회지
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• 제25권2호
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• pp.140-148
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• 2015

Vaccination is the most powerful and useful preparation against infectious diseases. However, developing vaccines costs a lot and requires extensive long-term efforts. Therefore, the government should research and develop vaccines with a national-level policy. To greatly enhance the success rate of vaccine development, the policy should be set up considering priorities such as the current status of domestic research, the importance for public health, the urgency of research. The Delphi technique was utilized to draft this survey, through a brainstorming stage, then two inquiries, and finally the final panel meeting where unresolved items were discussed, to draw the conclusion. Among the results, firstly, the highest ranked item on centralized fields for vaccine development by the Ministry of Health was 'self-sufficiency of vaccines.' Secondly, 'emerging infectious disease' was most highly ranked in prioritized fields of vaccine development and research. Thirdly, for the vaccine that needs to be improved and developed further by the government to improve its efficacy and safety, BCG (Bacille de Calmette) for tuberculosis was ranked the highest on both types (intradermal and subcutaneous injection) from National Immunization Programme (NIP) and non-NIP. As for the high risk pathogens, 'anthrax' and 'smallpox' were first and second, consecutively. Lastly, 'development and control of vaccine candidates' was ranked the highest for the area in need for technique development in order to improve domestic vaccine's research level. The results of this study will be put to good use as basic data for the national vaccine research and development (R&D) policy of the country. This study was first step and more studies should be carried out for the final decision of the national vaccine R&D priority.

• Journal of Medicine and Life Science
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• 제21권3호
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• pp.72-77
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• 2024

Enterohemorrhagic Escherichia coli (EHEC) produces Shiga toxin, which causes diarrhea, hemorrhagic colitis, and hemorrhagic uremic syndrome. The Korea Center for Disease Control and Prevention (KCDC) has designated EHEC as a legal infectious disease and has conducted laboratory surveillance. This study aimed to compare the demographic, epidemiological, clinical, and laboratory characteristics of EHEC cases in Jeju Province between August 2017 and November 2023, notified by two registry routes. The data were sourced from the integrated disease health and health management system managed by the KCDC. Cases reported due to experiencing gastrointestinal symptoms, or contacts of each case were defined as the "symptomatic" group. In contrast, cases with positive findings during a health checkup or laboratory surveillance were defined as the "screening" group. The symptomatic and screening groups had 35 and eight patients, respectively. There were significant differences in the age and seasonal distribution. The selection group was 20-59 years old in the main age distribution and registered evenly throughout the four seasons. In comparison, the symptomatic group was younger or older and not registered in the winter. These findings may be used to establish a more appropriate surveillance system for diarrheal outbreaks.

• 한국재난정보학회 논문집
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• 제19권3호
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• pp.451-470
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• 2023

연구목적: COVID-19가 2019년 12월에 중국에서 처음 발견된 이후 전 세계로 빠르게 확산되면서, 개인의 생활뿐만 아니라 기업과 국가에도 심각한 경제적·사회적 문제를 야기하였다. 개인, 기업, 정부 모두는 COVID-19의 확산을 방지하기 위하여 다양한 노력을 하였다. 감염병에 대응하고 관리하기 위해서는 개인, 기업, 정부 모두의 역할이 중요하나 선행연구에서는 부분적으로만 연구를 진행하였다. 따라서 본 연구에서는 감염병 재난관리 대응에서 성과를 내기 위해 개인, 기업, 정부의 역할에 대해 종합적으로 연구를 진행하였으며, 감염병 재난관리에 대한 근로자의 인식과 정부 및 기업 역량이 재난대응 성과에 미치는 영향을 파악하고자 하였다. 연구방법: 설문조사는 울산, 경주, 양산지역의 자동차 제조업 종사자를 대상으로 실시하였고, 분석은 빈도분석, 요인분석, 상관관계분석, 회귀분석을 실시하였다. 연구결과: 근로자 인식은 재난관리성과 뿐만 아니라 정부역량과 기업역량 모두에 긍정적인 영향을 주는 것으로 나타났다. 또한 정부역량과 기업역량은 재난관리성과에 긍정적인 영향을 주었다. 결론: 본 연구의 결과는 재난대응 성과를 달성하기 위해서는 근로자의 인식뿐만 아니라 정부와 기업의 역량이 중요함을 밝혔다는 점에서 의미를 가진다. 뿐만 아니라 근로자들은 정부와 기업에서 주어지는 교육과 참여의 기회를 잘 활용하고 근로자가 할 수 있는 범사회적인 노력을 기울여야 할 것이다.

• Parasites, Hosts and Diseases
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• 제59권5호
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• pp.507-512
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• 2021

Since 1993, vivax malaria has been recognized as a public health burden in Korea. Despite of pan-governmental malaria-control efforts and the dramatic reduction in the burden of this disease over the last 10 years, vivax malaria has not been well controlled and has remained continuously endemic. We focused interviewed and examined the charts of 28 confirmed vivax malaria patients given malarial therapy for whom daily records were kept from Gimpo-si, Gyeonggi-do of Korea. Various epidemiological characteristics of vivax malaria, including the incubation period, medication used, and recurrence, and an evaluation of the parasitic characteristics from the focused interviews of patients from this region are described here. Most of the participants indicated the 3 most common symptoms of malaria (headache, chills and fever). Of the 28 cases, 2 experienced a second attack and there were 17 and 11 cases with short- and long-term incubation periods, respectively, yielding a short-term to long-term ratio of 1.5. Based on the parasitemia stages, most of the participants were tested at 5 to 7 days (11 cases) and 7 to 15 days (11 cases) after initial wave of asexual parasites. In conclusion, public health authorities should consider developing management measures to decrease the time lag for diagnosis and drafting unified and robust guidelines for drug use for malaria and drawing up unified and robust guidelines on the use of medication for malaria. It also suggests that routine monitoring, surveillance, and precise medical surveys in high-risk vivax malaria endemic areas are pivotal to controlling this persistent public disease and finally eliminating it from Korea.

• 디지털융복합연구
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• 제20권5호
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• pp.909-918
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• 2022

본 연구는 어린이집 원장을 대상으로 감염병 예방 교육요구도, 자기효능감을 파악하고 감염병 예방 자기효능감에 영향을 미치는 요인을 파악하고자 시행되었다. 연구는 G, J, S시 소재 어린이집 원장 172명을 대상으로 설문지를 이용하여 진행하였다. 수집된 자료는 SPSS 24.0 프로그램을 이용하여 기술통계, t-test, ANOVA, Pearson's correlation coefficient, Multiple regression analysis로 분석하였다. 연구 결과, 감염병 예방 교육요구도는 손 씻기 방법 및 시기, 세척과 소독 방법이 높았고, 감염병 예방 자기효능감은 영유아 손 씻기 교육과 시기가 가장 높았다. 감염병 예방 교육요구도와 자기효능감(r=.528, p<.001) 간에는 양의 상관관계가 있는 것으로 나타났다. 감염병 예방 자기효능감에 영향을 미치는 유의한 요인은 감염병 예방 교육요구도(β=.53, p<.001), 감염병 예방 교육의 경험(β=.25, p<.001)로 나타났다. 이러한 연구 결과는 어린이집 원장에 대한 감염병 예방에 대한 교육 요구를 충족시킬 수 있는 프로그램 개발이 필요하다는 것을 보여준다. 이러한 교육을 통해 어린이집 원장의 감염병 예방에 대한 자기효능감이 향상될 것이다.

• 한국ITS학회 논문지
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• 제21권4호
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• pp.78-95
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• 2022

아프리카 돼지열병, 구제역 등 가축전염병 유행과 관련된 기존의 연구 결과에서 가축전염병 확산의 주요 원인으로 축산 관련 차량 통행을 지목하는 경우가 많다. 이에 본 연구는 경기도 내 축산시설의 차량 방문이력 데이터와 화물차량의 디지털 운행기록계 데이터를 결합하여 각 읍면동의 주중 축산 화물차량 OD 통행량을 구한 후, 이에 기반한 가축전염병 확산 예측모형을 개발하였다. 모형은 2015년 1~2월 당시 주차별 구제역 발병기록을 이용하여 훈련되었으며, 긍정적 시나리오 기준으로 검증용 감염 표본 13개의 감염을 모두 예측해내는 데에 성공했다.

• The Journal of Korean Physical Therapy
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• 제34권6호
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• pp.304-311
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• 2022

Purpose: The purpose of this study was to investigate the knowledge, awareness and performance of COVID-19 infection control among physical therapists and to identify the impact factors on performance Methods: Data were collected from March 16th to March 24th in 2022 from the physical therapist's in Busan. Data analysis was conducted on 170 surveys, after excluding 27 surveys that were found to be unsuitable for data analysis. Results: When correlating the study variables, knowledge and awareness were found to have a positive, meaningful correlation with performance. Performance of COVID-19 personal infection control regression analysis showed that the working department (clinic and long-term care hospital), clinical experience, the more knowledgeable, the awareness (personal), and the more clinical experience had significant positive impacts on the performance of COVID-19 infection control. Performance of COVID-19 treatment room infection control regression analysis showed that the working department (long-term care hospital), educational experience, the awareness (treatment room) had significant positive impacts on the performance of COVID-19 infection control Conclusion: The results of this study may be used as basic data for educating physical therapist's working at the COVID-19 response department. This study suggests that physical therapist's need educational programs to improve their knowledge and awareness and performance of infection control against infectious diseases such as COVID-19. Differentiated physical therapists practice education curricula must be developed and provided after understanding the varying characteristic of physical therapist's with different levels of work experience.

• 한국어병학회지
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• 제35권2호
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• pp.167-176
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• 2022

We injected infectious myonecrosis virus (IMNV) to pacific whiteleg shrimp, Litopenaeus vannamei, and observed closely with using light microscope and transmission electron microscope (TEM) for 4-8 days post infection (dpi). As clinical signs, abdominal bodies had mild opaque muscles at 5 dpi. And the mortality was shown at 6 dpi. At 8 dpi, most injected shrimps had severe opaque muscles and humped back that cause of movement disorder. As results of histopathological examinations, local parts of abdominal body muscle had muscle fiber hyalinization, muscle fiber atrophy, rounded muscle fibers, myofibrillar hypertrophy in size, a decrease in number of myofibrils and phagocytosis from the sarcolemmas by multiple hemocytes at 4 dpi. Especially, myofibrillar hypertrophy appeared at the whole or random part of single muscle fiber not in specific locations like the center or edge of muscle fiber. At 6-7 dpi, multiple muscle necrosis, muscle fiber segmentation, myofibril lysis ap- peared and a few hemocytes were infiltrated at lesions. At 8 dpi, extensive muscle necrosis, multiple myofibril lysis and muscle fiber atrophy were shown, and very few hemocytes were infiltrated. In early stage of infection, local viral myositis with zenker's degeneration were shown. These lesions appeared multiply after the early stage. In late stage of infection, extensive coagulative muscle necrosis appeared with few of inflammatory response such as hemocytes infiltration. The lack of hemocytes infiltration response at the late stage might be disadvantage for Litopenaeus vannamei to defense against IMNV and to recover, because hematocytes (granulocyte, semi-granulocyte) eliminate pathogen and damaged tissues from infection sites and help recover. As results of the TEM observation, IMNVs that had nonenveloped icosahedral capsid which was 30-40 nm diameter were in myofibril and beside tubules of sarcoplasmic reticulum and moved to the certain direction. The micro-tears and micro-trau- mas in myofibrils caused muscle fiber necrosis. And semi-granulocytes engulfed IMNVs to eliminate virus.

• 한국융합학회논문지
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• 제8권10호
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• pp.147-153
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• 2017

본 연구의 목적은 공공병원을 대상으로 감염병 예방관리의 관점에서 법 제도, 감시체제, 대응관리체계가 조직시민행동에 어떠한 영향을 미치며 조직신뢰의 조절효과를 검증하고자 한다. 연구의 절차로 이론적 논의와 실무적 관점에서 감염병의 예방적 대응과 시민들의 협력적 행동의 인과적 관계에서 조직신뢰의 조절효과를 확인하는데 의미가 있다고 본다. 분석결과 감염병 예방관리에서 감시체계와 비상대응체계보다 강한 관계를 나타내고 있으며, 그 중요성이 높다고 보고 있다. 그 이유는 해외여행과 교류가 과거보다 훨씬 증가하였고, 이에 대한 감염경로 비중이 다소 많은 비중을 보이기 때문으로 본다. 따라서, 향후 공공병원을 운영하면서 조직신뢰의 중요성이 주목받고 확고한 이론적인 기반을 토대로 현장에서 실효적인 조직관리가 이루어지기를 기대한다.

• 한국동물위생학회지
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• 제35권2호
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• pp.91-97
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• 2012

The strategy for infectious bursal disease (IBD) control and its success rate under field conditions depends on hygiene management, IBD field pressure, level, and variation in maternally derived IBD antibodies. This study investigated the level of IBD-specific antibody by ELISA and the prevalence of IBD virus by PCR in broilers, white-semi broilers, and Korean native chickens raised in Jeongeup, Jeonbuk. IBD-specific maternally derived antibodies were measured from 698 chickens and the mean titers of maternal antibodies were $3,572{\pm}1,402$ in broilers, $1,262{\pm}762$ in white-semi broilers, and $1,932{\pm}912$ in Korean native chickens. At 2 weeks after vaccination, the geometric mean antibody titers of broiler, white-semi broiler, and Korean native chicken were $582{\pm}427$, $3255{\pm}1,080$, and $1,023{\pm}499$, respectively. According to sequence analysis of the variable virion protein 2 gene, 4 isolates were found to be very virulent IBDV, 9 isolates classical virulent, and 2 isolates intermediate plus vaccine strain.