• Journal of Korean Clinical Nursing Research
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• v.29 no.2
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• pp.175-185
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• 2023

Purpose: The purpose of this study was to investigate the influence of nurses on the nursing intentions in patients with emerging infectious diseases. Methods: Data were collected from 201 nurses with over one year of clinical experience in a general hospital located in Seoul, South Korea. A structured self-report questionnaire was utilized to measure belief factors, core factors, rewards, and nursing professional pride, as well as nursing intentions in patients with emerging infectious diseases. Results: The results revealed that nurses' intentions to provide care for patients with emerging infectious diseases were significantly influenced by perceived behavioral control (β=.26, p<.001), clinical experience (β=-.14, p=.008), behavioral beliefs (β=.31, p=.010), feeling of vocation (β=.29, p=.012) and attitudes toward behaviors (β=.08, p=.034). Conclusion: Enhancing nurses' intentions to provide care for patients with emerging infectious diseases requires the implementation of systemic and educational strategies aimed at strengthening their confidence and beliefs.

• Journal of the Korean Society of Safety
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• v.37 no.2
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• pp.88-96
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• 2022

Widespread infectious diseases are a concern for workers working in confined spaces. However, there is no risk assessment index for the risk of infectious disease in the workplace. Therefore, we propose a simple but effective index model to assess the risk of infectious diseases in the workplace. The proposed model identifies the risk of each workplace through an evaluation sheet comprising the frequency and intensity of the infectious disease. The intensity of an infectious disease is generally governed by the density of workers, whereas frequency is the sum of physical-e nvironmental and human management factors. By multiplying intensity and frequency, the risk of the workplace is derived. Through the proposed model, we evaluate the risks of workers at 15 different work sites. The proposed model clearly reveals what should be improved to keep workers safe from infectious diseases and will be helpful in assessing the risk of contagious disease at the work place.

• Journal of Microbiology and Biotechnology
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• v.23 no.8
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• pp.1167-1175
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• 2013

Paratuberculosis (PTB) or Johne's disease is one of the most serious chronic debilitating diseases of ruminants worldwide that is caused by Mycobacterium avium subsp. paratuberculosis (MAP). MAP is a slow-growing bacterium that has very long latent periods, resulting in difficulties in diagnosing and controlling the disease, especially regarding the diagnosis of fecal shedders of MAP without any clinical signs. Based on this situation, attempts were made to identify biomarkers that show early responses to MAP infection in a macrophage cell line, RAW 264.7. In response to the infection with the bacterium, a lot of genes were turned on and/or off in the cells. Of the altered genes, three different categories were identified based on the time-dependent gene expression patterns. Those genes were considered as possible candidates for biomarkers of MAP infection after confirmation by quantitative RT-PCR analysis. To the best of our knowledge, this is the first attempt at discovering the host transcriptomic biomarkers of PTB, although further investigation will be required to determine whether these biomarker candidates are associated within the natural host.

• The Journal of Korean Academic Society of Nursing Education
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• v.30 no.1
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• pp.71-81
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• 2024

Purpose: This study aimed to identify the relationship between nursing professionalism and nursing intention for patients with emerging infectious diseases of nursing students who had experienced coronavirus disease 2019 (COVID-19), with a focus on the mediating effect of e-Health literacy. Methods: The study surveyed 177 nursing students who had experienced COVID-19. The data were collected using self-reported questionnaires. The collected data were analyzed using IBM SPSS statistics 25.0, and the mediating effect was analyzed through the SPSS Process macro model 4. Results: Nursing professionalism (β=.26, p=.002) and e-Health literacy (β=.18, p=.021) were found to be significant predictors of nursing intention for patients with emerging infectious diseases. In addition, e-Health literacy partially mediated the relationship between nursing professionalism and nursing intention for patients with emerging infectious diseases. Conclusion: e-Health literacy was a mediating factor in the relationship between the nursing professionalism and nursing intention of nursing students for patients with emerging infectious diseases. In order to improve nursing intention of nursing students for patients with emerging infectious diseases, it is important to develop an education program that can enhance their e-Health literacy as well as nursing professionalism.

• CELLMED
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• v.1 no.1
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• pp.3.1-3.4
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• 2011

Emerging infectious diseases are usually a public concern. The presence of new emerging infectious diseases is a topic to be reported on and discussed about in medicine. Several new emerging infectious diseases have occurred within the present decade. In this specific review, the author briefly reviews the important new emerging human viral infections that first appeared in Asia during the present decade, 2001 - 2010.

• Proceedings of the Microbiological Society of Korea Conference
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• 2005.05a
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• pp.230.2-230
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• 2005

• Journal of the Korea Society of Computer and Information
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• v.28 no.12
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• pp.201-209
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• 2023

This study investigated to provide basic data for infection control education on new infectious diseases by confirming the level of knowledge, training status, stress, and need for training on new infectious diseases for 119 emergency medical technicians (EMT). This data collection period was a total of 39 days from August 10 to September 18, 2022, and a total of 105 copies were collected. The analysis of this study used the SPSS 25.0 program. As a result of the study, among the 119 paramedics, the gender of the EMT was 54 men (51.4%) and 51 women (48.6%), with more men than women, with 47 people in their 20s (44.8%) and those in their 30s or older. There were 58 people (55.2%), most of whom were in their 30s or older. The highest total work experience was 3 to 5 years (37 people (35.2%)). In the pandemic situation, an attempt was made to check the education status of 119 paramedics on COVID-19 and the need for education on new infectious diseases. As a result of the study, the status of education on COVID-19 was insufficient. The demand for education on new infectious diseases was found to be high. Among 119 emergency responders who are frequently exposed to new infectious diseases, theoretical and practical training in personal protective equipment, stress, including theoretical training, is needed. A theoretical and practical education program on new infectious diseases and personal protective equipment should be developed as a subject for college students before becoming EMT.

• Parasites, Hosts and Diseases
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• v.60 no.1
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• pp.39-43
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• 2022

Plasmodium vivax exhibits dormant liver-stage parasites, called hypnozoites, which can cause relapse of malaria. The only drug currently used for eliminating hypnozoites is primaquine. The antimalarial properties of primaquine are dependent on the production of oxidized metabolites by the cytochrome P450 isoenzyme 2D6 (CYP2D6). Reduced primaquine metabolism may be related to P. vivax relapses. We describe a case of 4 episodes of recurrence of vivax malaria in a patient with decreased CYP2D6 function. The patient was 52-year-old male with body weight of 52 kg. He received total gastrectomy and splenectomy 7 months before the first episode and was under chemotherapy for the gastric cancer. The first episode occurred in March 2019 and each episode had intervals of 34, 41, and 97 days, respectively. At the first and second episodes, primaquine was administered as 15 mg for 14 days. The primaquine dose was increased with 30 mg for 14 days at the third and fourth episodes. Seven gene sequences of P. vivax were analyzed and revealed totally identical for all the 4 samples. The CYP2D6 genotype was analyzed and intermediate metabolizer phenotype with decreased function was identified.

• Journal of Microbiology
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• v.45 no.2
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• pp.168-170
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• 2007

In this research 26 Shigella isolates were examined by PCR and direct nucleotide sequencing for genetic alterations in the quinolone-resistance determining regions (QRDRs). We tested for the presence of qnr genes by PCR in 91 strains, but no qnr genes were found. The results did show, however, some novel mutations at codon 83 of gyrA ($Ser{\rightarrow}Ile$) and codon 64 of parC ($Ala64{\rightarrow}Cys,\;Ala64{\rightarrow}Asp$), which were related to fluroquinolone resistance.

• Journal of Microbiology and Biotechnology
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• v.15 no.6
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• pp.1368-1376
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• 2005

Pseudomonas aeruginosa produces a variety of bacteriocidal substances including pyocins that are active against the same species, but their physiological roles are relatively unknown. Here, we profiled the bacteriocidal activities in the culture supernatants of various P. aeruginosa isolates and describe the competitive growth advantages of strains PAO1 and PA14 over some strains including PAK, which are sensitive to their bacteriocidal activities. These findings suggest that the factors governing the production of pyocins and the resistance to them play important roles in controlling P. aeruginosa populations in its local environments.