• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.3
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• pp.1270-1277
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• 2011

Since the pharmaceutical industry is a research oriented sector, the research and development capability based on the qualified R&D manpower is one of the key success factors to strengthen the national competitiveness. Securing the appropriate number of researcher needed for the research activities in these fields is an important precondition for a government policy that aims for a strongly knowledge-intensive the pharmaceutical industry growth. In this study, we conducted and analyzed a delphi survey of the experts(the principal investigators) with expertise in these pharmaceutical research areas. The current and future requirements for the pharmaceutical science research personnel including medical doctors have been evaluated, extending the year 2017. The results of this study can be summarized as follows; First, in 2007 the field of pharmaceutical R&D personnel is currently under-supplied as many as about 5,600 people. The rate of under-supplied is about 18.1%. Second, in 2017 the evaluation shows that the R&D personnel in this field will be more severely under-supplied as many as 13,500 people. The rate of under-supplied will be about 28.6%. As a result, the confrontation of demand and supply evaluation shows that, in general, severe shortages of R&D manpower in the field of pharmaceutical will result if there are not adequate manpower policy adjustment.

• Korean Medical Education Review
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• v.13 no.2
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• pp.47-57
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• 2011

Purpose: This study was conducted to explore the current usage of high integration mannequin human patient simulators (hereafter HPS) in nursing education. Methods: Thirty-two faculty members in 11 nursing schools participated in this survey. the questionnaire consisted of some multiple-choice questions and open questions to collect data on the experience of faculty members with using HPS as well as quantitative information. Results: The faculty members who used HPS in their classes recognized the need to use simulation in nursing education. They identified the advantages of simulation education as promoting adaptation to the clinical environment(46.9%), promoting self-confidence(28.1%), promoting critical thinking(28.15), and making direct nursing skill practice available(28.1%). However, they considered the obstacles to the use of simulation in nursing education to be insufficient manpower(62.5%), insufficient time(40.6%), and difficulty in preparing a teaching strategy(34.4%). Conclusion: HPS is useful in nursing education, but systematic plans and policies regarding on its operation are needed to confirm its effectiveness. The results of this study generally provide a basic information for use of HPS in nursing education.

• Journal of the Korean Wood Science and Technology
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• v.52 no.5
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• pp.504-523
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• 2024

Timber industry waste is being examined for cellulose manufacturing to give important benefits. The study's goal is to investigate the properties of cellulose powder derived from sawdust waste after it has been reinforced with ferrous-ferric oxide nanoparticles (Fe₃O₄-NPs). Sawdust cellulose powder was produced from Sengon (Albizia chinensis) wood waste in this study. The crushed sawdust waste is handled with alkalization and bleaching. Cellulose powder is then reinforced with Fe₃O₄-NPs at 10 wt.%, 20 wt.%, and 30 wt.%. The magnetic cellulose powder was analysed by X-ray diffraction, Fourier Transform Infrared, scanning electron microscopy morphology, magnetic vibrating sample magnetometer, Brunauer-Emmett teller, and adsorption tests for Methylene Blue and Congo Red dyes. Structure study identifies sawdust as cellulose 1β, with peaks at 14°, 16°, and 22° diffraction angles. The addition of Fe₃O₄-NPs reduces the crystalline index of sawdust cellulose powder from 68.50% to 63.38%, and functional group bond analysis revealed many peak shifts indicating a change in the chemical bonds of magnetic cellulose powder. Incorporating Fe₃O₄-NPs into sawdust cellulose powder confers magnetic and superparamagnetic properties to the sawdust cellulose. Similarly, the surface texture of magnetic cellulose seems rougher as the surface area increases. These parameters imply a 31.8% increase in Congo Red adsorption, using adsorption kinetics based on the pseudo-first-order model.

• Journal of Korea Entertainment Industry Association
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• v.14 no.7
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• pp.651-658
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• 2020

The basic medical subjects are essential for the understanding of the major in the department of health science and are very important. Anatomy is one of the fundamental areas of medical education. On the other hand, the application of new teaching method is being attempted in various fields. Station rotation model, one of the blended learning, is also one of the popular teaching method. Station rotation model allows students to rotate through stations on a fixed schedule, where at least one of the stations is an online learning station. This study investigate the satisfaction of students when applying station rotation model to anatomy class. Each station in the station rotation model consisted of VR application learning, online problem solving, model observation and oral test. After applying station rotation model (2 weeks) to the 'Functional anatomy and Practice' course taken by 37 students of the'Department of Occupational Therapy'at H University, this study conducted a satisfaction survey compare with lecture class for students taking the course. At the result, station rotation model was significantly higher than lecture class in both understanding, interest, concentration and diversity degree. Based on these results, I suggest applying the station rotation model to the anatomy class because it also showed high satisfaction in that.

• Perspectives in Nursing Science
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• v.7 no.1
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• pp.23-35
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• 2010

Purpose: The purpose of this paper is to analyze the demand and supply of advanced practice nurses and suggest alternative benefit strategies in the Korean national health insurance. Methods: A revised demand & supply model was used to estimate the excess supply of APNs, and policy making process and key actors in the Korean health insurance were considered to develop a political approach to the APN issue. Results: The social demand for APNs is currently estimated to be less than 50% of its supply and the APN education program fell into difficulties in recruits. No reimbursement mechanism for APN's services in the national health insurance has given no economic incentive to hospital managers who have monopsony power in nursing labor market, which has caused the demand shortage of APNs in hospital industry. Payment for APN's services recognized as one of the most significant strategies to booster the social demand for APN's services should be carefully designed and implemented in the national health insurance. In line with this, key actors in health insurance policy decision-making include government, national assembly, labor unions, NGOs, civic groups, medical associations, and academia. Conclusion: The basic researches for APN's activities and cost-effectiveness analysis in clinical settings are required to support the strategies aforementioned. Constructing a policy network among key actors is able to make the payment strategy feasible, which will increase the socal demand for APNs.

• Journal of Animal Reproduction and Biotechnology
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• v.39 no.2
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• pp.131-137
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• 2024

Background: Porcine embryonic development is widely utilized in the medical industry. However, the blastocyst development rate in vitro is lower compared to in vivo. To address this issue, various supplements are employed. Extracellular vesicles (EVs) play the role of communicators that carry many bioactive cargoes. Additionally, the contents of EVs can vary on the estrous cycle. Methods: We compared the effects of adding EVs derived from porcine uterine fluid (UF), categorized as non-EV (G1), EVs in estrus (G2) and EVs in diestrus (G3). After in vitro culture (IVC) was performed in three different groups, cleavage rate and blastocyst development rate were examined. In addition, glutathione (GSH) and reactive oxygen species (ROS) levels were measured 2 days after activation to assess oxidative stress. Results: Using NTA and cryo-TEM, we confirmed the presence of EVs with sizes ranging from 30 nm to 200 nm, that the particles were suitable for analysis for analysis. In IVC data, the highest cleavage rate was observed in G2, which was significantly different from G1 but not significantly different from the next highest, G3. Similarly, the highest blastocyst development rate was observed in G2, which was significantly different from G1 but not significantly different from the next highest, G3. Conclusions: These results indicate that estrus derived EVs contain biofactors beneficial for early blastocyst development, including GSH which protects the blastocyst from oxidative stress. Additionally, although diestrus-derived EVs are expected to have some effect on blastocyst development, it appeared to be less effective than estrus-derived EVs.

• International journal of advanced smart convergence
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• v.5 no.1
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• pp.1-7
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• 2016

Recently, introduced a cloud computing technology to the IT industry, smart phones, it has become possible connection between mobility terminal such as a tablet PC. For dissemination and popularization of movable wireless terminal, the same operation have focused on a viable mobile cloud in various terminal. Also, it evolved Wireless Sensor Network(WSN) technology, utilizing a Body Sensor Network(BSN), which research is underway to build large Ubiquitous Sensor Network(USN). BSN is based on large-scale sensor networks, it integrates the state information of the patient's body, it has been the need to build a managed system. Also, by transferring the acquired sensor information to HIS(Hospital Information System), there is a need to frequently monitor the condition of the patient. Therefore, In this paper, possible sensor information exchange between terminals in a mobile cloud environment, by integrating the data obtained by the body sensor HIS and interoperable data DBaaS (DataBase as a Service) it will provide a base of mBodyCloud System. Therefore, to provide an integrated protocol to include the sensor data to a standard HL7(Health Level7) medical information data.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.929-935
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• 2014

Two types of nanosized titanium dioxide, anatase ($anTiO_2$) and rutile ($rnTiO_2$), are widely used in industry, commercial products and biosystems. $TiO_2$ has been evaluated as a Group 2B carcinogen. Previous reports indicated that $anTiO_2$ is less toxic than $rnTiO_2$, however, under ultraviolet irradiation $anTiO_2$ is more toxic than $rnTiO_2$ in vitro because of differences in their crystal structures. In the present study, we compared the in vivo and in vitro toxic effects induced by $anTiO_2$ and $rnTiO_2$. Female SD rats were treated with $500{\mu}g/ml$ of $anTiO_2$ or $rnTiO_2$ suspensions by intra-pulmonary spraying 8 times over a two week period. In the lung, treatment with $anTiO_2$ or $rnTiO_2$ increased alveolar macrophage numbers and levels of 8-hydroxydeoxyguanosine (8-OHdG); these increases tended to be lower in the $anTiO_2$ treated group compared to the $rnTiO_2$ treated group. Expression of $MIP1{\alpha}$ mRNA and protein in lung tissues treated with $anTiO_2$ and $rnTiO_2$ was also significantly up-regulated, with $MIP1{\alpha}$ mRNA and protein expression significantly lower in the $anTiO_2$ group than in the $rnTiO_2$ group. In cell culture of primary alveolar macrophages (PAM) treated with $anTiO_2$ and $rnTiO_2$, expression of $MIP1{\alpha}$ mRNA in the PAM and protein in the culture media was significantly higher than in control cultures. Similarly to the in vivo results, $MIP1{\alpha}$ mRNA and protein expression was significantly lower in the $anTiO_2$ treated cultures compared to the $rnTiO_2$ treated cultures. Furthermore, conditioned cell culture media from PAM cultures treated with $anTiO_2$ had less effect on A549 cell proliferation compared to conditioned media from cultures treated with $rnTiO_2$. However, no significant difference was found in the toxicological effects on cell viability of ultra violet irradiated $anTiO_2$ and $rnTiO_2$. In conclusion, our results indicate that $anTiO_2$ is less potent in induction of alveolar macrophage infiltration, 8-OHdG and $MIP1{\alpha}$ expression in the lung, and growth stimulation of A549 cells in vitro than $rnTiO_2$.

• Journal of Korean Dental Hygiene Science
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• v.6 no.2
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• pp.141-150
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• 2023

Background: This study was conducted to verify the effectiveness of geriatric dental hygiene education by developing and operating an industrial demand-based curriculum for geriatric dental hygiene. Methods: Wilcoxon signed rank test was performed to verify the before-and-after differences in major competency achievement, geriatric dental hygiene awareness, and class satisfaction according to industrial demandbased field-oriented practical education, and Spearman's correlation analysis was performed to confirm the association between each factor(p<0.05). Results: In the case of major competency achievement, 'communication competence with the older adults' was significantly improved(p=0.031) after conducting industrial demand-based field-oriented practical training. Conclusion: It is believed that the understanding of the older adults and the practical skills for oral care of the older adults can be further developed when the learners are provided with a practical curriculum that can be used in the geriatric industrial field.

• Journal of the Korean Society of Radiology
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• v.6 no.6
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• pp.507-513
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• 2012

This research was performed to evaluate the superparamagnetic iron oxide nanoparticles'(SPIONs) cell toxicity and to measure the radiation cell survival curve changes of SPIONs-uptake glioblastoma multiforme cells. The results could be practically used as the fundamental data to ameliorate proton beam cancer therapy, for example, providing necessary GBM treatment dose in the proton beam therapy when the therapy takes advantage of SPIONs. The assessment of the toxicological evaluation of synthesized SPIONs was accomplished by MTT assay as an in vitro experiment. The results showed no meaningful differences in the cell survival rate at the $1-100{\mu}g/ml$ SPIONs concentrations, but the cell toxicity was shown as the cell survival rate decreased up to 74.2% at the $200{\mu}g/ml$ SPIONs concentration. Then, we measured each radiation cell survival curve for U373MG cells and SPIONs-uptake U373MG cells with 0~5 Gy of proton beam irradiations. It is learned from the analysis of the experimental results that the SPION-uptake cells' radiation survival rate was more rapidly decreased as the irradiation dose increased. In conclusion we confirmed that SPIONs-uptake in U373MG cells induces cell death at the much less dose than the lethal dose of SPION-non-uptake cell. This research shows that the therapeutic efficacy of glioblastoma multiforme treatment in proton beam therapy can be improved by SPIONs targeting to the GBM cells.