• Journal of Microbiology and Biotechnology
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• 제13권4호
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• pp.522-528
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• 2003

The growth responses of Phellodendron amurense root-derived materials against seven intestinal bacteria were examined, using an impregnated paper disk agar diffusion method and spectrometric method under $O_2$-free condition. The biologically active constituent of the P. amurense root extract was characterized as berberine chloride ($C_{20}H_{18}NO_{41}Cl$) using various spectroscopic analyses. The growth responses varied depending on the bacterial strain, chemicals, and dose tested. At 1 mg/disk, berberine chloride strongly inhibited the growth of Clostridium perfringens, and moderately inhibited the growth of Escherichia coli and Streptococcus mutans without any adverse effects on the growth of three lactic acid-bacteria (Bifidobacterium bifidum, B. longum, and Lactobacillus acidophilus). The structure-activity relationship revealed that berberine chloride exhibited more growth-inhibiting activity against C. perfringens, E. coli, and S. mutans than berberine iodide and berberine sulfate. These results, therefore, indicate that the growth-inhibiting activity of the three berberines was much more pronounced as chloridated analogue than iodided and sulphated analogues. As for the morphological effect caused by 1 mg/disk of berberine chloride, most strains of C. perfringens were damaged and killed, indicating that berberine chloride showed a strong inhibition against C. perfringens. As naturally occurring growth-inhibiting agents, the P. amurense root-derived materials described could be useful as a preventive agent against diseases caused by harmful intestinal bacteria such as clostridia.

• Biotechnology and Bioprocess Engineering:BBE
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• 제5권5호
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• pp.350-354
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• 2000

The growth promotion of a Taxus brevifolia cell suspension culture was investigated using conditioning factors. The conditioning factors produced and secreted from cultured cells usually stimulate cell division and the production of secondary metabolites. Therefore, the effective incubation time for the optimal secretion of conditioning factors was firstly determined for the promotion of cell growth. Conditioned media obtained by cultivating for 2 and 5 days showed the promotion of initial cell growth during the early cell growth period. However, the positive effect of the conditioning factors on the initial cell growth did not continue because of the depletion of the medium nutrients. Accordingly, the addition of a carbon source to the conditioned medium prolonged the positive effect on the cell growth. The addition of sucrose to the conditioned medium resulted in the maximum cell density being reached 4 days earlier compared to the control group and an increased substrate yield.

• 유통과학연구
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• 제12권4호
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• pp.65-72
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• 2014

Purpose - Because of the emphasis on the necessity of academic-industrial cooperation between companies and universities, there are various ongoing academic-industrial cooperation programs led by the government. As government actively supports such cooperation as policy,and universities vitalize new technology development, academic-industrial cooperation between companies and universities is being recognized as an important growth engine for companies the competitiveness of academic-industrial cooperation is also attracting more interest. The government has vitalized human resource fostering, practical R&D, and technology transfer to companies since 2012 by executing a "leading university fostering project for academic-industrial cooperation." Based on an organic interlink among universities, industry, and research institutes, the government also created and is promoting several models of such cooperation between companies and universities to support shared growth of industry and local universities. The purpose of academic-industrial cooperation is growth and benefit fromtechnology development, technical cooperation, and technology transfer between companies and universities. Research design, data, and methodology - As more academic-industrial cooperation efforts are ledby companies due to the limitation in technology-focused commercialization cooperation, the academic-industrial cooperation system became fragmented and it is losing the potential for future advancement. Specifically, as differences between universities grow, academic-industrial cooperation between companies and universities based on new technology from universities is finding difficulty advancing,while systematic support from companies to enhance the performance of businesses created by academic-industrial cooperation is also insufficient. Accordingly, this study established a growth model for the advancement of academic-industrial cooperation between companies and universities and suggested a plan to strengthen the competitiveness and promote the future advancementof academic-industrial cooperation between companies and universities by analyzing the current situation of such cooperation and diagnosing its issues. Results - This study explored the concept and current status of academic-industrial cooperation relationships and analyzed related issues. For such cooperative organizations to be competitive, the employment environment of professional human resources for academic-industrial cooperation should be improved and measures to secure professional resources should be taken as early as possible. Though the academic-industrial cooperation now is being led by government, there is a limitation based on business models, which require creation of profit; however, an academic-industrial cooperation model still cannot stand alone without the support of government. This study also pointed out that a having only a plan to build competitiveness of companies and universities for academic-industrial cooperation is not sufficient. Conclusions - In order to increase the competitiveness of academic-industrial cooperation, a detailed growth-sharing model for academic-industrial cooperation should be developed, and there should be more joint development processes for the advancement of such cooperation in which the need for technology development can be verified in advance. In addition, beyond focusing on technology-focused academic-industrial cooperation, a network between companies and universities searching for ideas for academic-industrial cooperation in the fields of human and social aspects should be created. A new academic-industrial model linking current cooperation between companies and universities to the local area should be built based on such academic-industrial cooperation in human and social fields.

• 기술사
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• 제34권2호
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• pp.28-30
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• 2001

In now, the Industrial plant has been situated by the difficult status in Korea. But maybe we want to look for development direction of Industrial plant technology in order to overcome this difficult economic situation. And we should overcome this difficult position by restructuring our industrial plant part and by preconsiderating our future economic circumstances . This paper will a little help us to know the growth direction of industrial plant technology in Korea.

• 한국산업융합학회 논문집
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• 제20권5호
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• pp.351-357
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• 2017

Growing plant in potting media without soil is known as Soilless cultivation. This method is used mostly in greenhouse cultivation to increase horticultural commodities production. Peat moss is commonly utilized as potting media substrate because of its characteristic. However, peat moss price is high because of the quantity of peat moss in nature has been decreased. Recently, most of the research is conducted to find the alternative growing medium to cultivate horticulture plant in potting media. Perlite and rice husk ash were mentioned that had a potent as alternative growing media for seasonal plants to increase agriculture production due to the lack of production area. This study aimed to determine the effect of using different substrate and growth performance of chili. The method used was the soilless cultivation. The chili was planted in the pot with perlite media, rice husk ash media, and peat moss media. The chili was measured after 65 days after planting. The result showed that rice husk ash and perlite were more potentials in chili growth performance than peat moss. Rice husk ash had the significant result of plant height. While, Perlite effect on root length, plant weight, leaf length, and stem diameter. The best alternative for cultivation chili without substrate based on this research was perlite then rice husk ash and peat moss.

• 한국산업융합학회 논문집
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• 제22권1호
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• pp.55-60
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• 2019

Growing plant in potting media without soil is known as Soilless cultivation. This method is used mostly in greenhouse cultivation to increase horticultural commodities production. Peat moss is commonly utilized as potting media substrate because of its characteristic. However, peat moss price is high because of the quantity of peat moss in nature has been decreased. Recently, most of the research is conducted to find the alternative growing medium to cultivate horticulture plant in potting media. Perlite and rice husk ash were mentioned that had a potent as alternative growing media for seasonal plants to increase agriculture production due to the lack of production area. This research aims to determine the growth of in rice husk ash, perlite and peat moss as growing substrates. The method used was the soilless cultivation. The chinese cabbage was planted in the pot with perlite media, rice husk ash media, and peat moss media. The chinese cabbage was measured after 35 days after planting. The result showed that peatmoss was more potentials in chinese cabbage growth performance than rice husk ash and perlite. Peat moss had the significant result of every research parameters such as plant height, plant weight, number of leaves, plant diameter, root length, and root weight. The best alternative for cultivation chinese cabbage without substrate based on this research was peat moss then rice husk ash and perlite.

• 품질경영학회지
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• 제31권1호
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• pp.11-20
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• 2003

In the development of a complex systems, the early prototypes generally have reliability problems, and, consequently these systems are subjected to a reliability growth program to find problems and take corrective action. A variety of models have been proposed to account for the reliability growth phenomena. Clear guidelines need to be established to assist the reliability engineers for model selection. In this paper, some of more well-known growth models are surveyed and classified. These models are classified based upon distinguishing model features. A procedure for model selection is introduced which is based on this classification.

• 산업공학
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• 제19권1호
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• pp.19-25
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• 2006

In the development process, the objective of a reliability growth program is to track the increase in system reliability, and determine as early as possible whether or not the system reliability is growing at a sufficient rate to meet the required goal and allocate available resources accordingly. Implementation of this kind of program will provide very useful information on concept selection, product/process reliability, and cost effectiveness without too much time, money and engineering effort being spent on the development of failure suspect parts. The purpose of this research is to present a practical method for efficiently monitoring a reliability growth test process using AMSAA(Army Materiel Systems Analysis Activity) reliability growth model. The presented growth management is a viable method for identifying failure modes, incorporating design changes and monitoring reliability progress on an on-going basis during the early stages of a product development program.

• 산업융합연구
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• 제14권1호
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• pp.39-45
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• 2016

This paper deals with the consideration of mathematical models with regards to growth of cluster and firms by reviewing the Metcalf and Breuner's articles. prior studies have been argued the phenomenon of local industrial clusters and districts. Several concepts have been adopted to support the success of and changes to these clusters and firm growth. Through the review of two papers, evolution of both cluster and firm growth may be achieved in terms of utilizations of the different local aspects and mechanisms. This paper supports the theoretical back bone with regards to the regional cluster policy implementing in Korea for the purpose of regional developments. In particular, a mathematical model that, on a more abstract level, captures the fundamental dynamic structure of all the observed mechanisms. On the basis of this model, the emergence and evolution of local clusters can be described. Also this model has given that the knowledge sharing between firms has an important role to firms and cluster' growth.

• 한국결정성장학회지
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• 제32권5호
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• pp.169-174
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• 2022

본 연구는 재생된 SiC 분말을 이용하여 단결정 성장 가능성을 검증하는 것을 목적으로 한다. 재활용 분말의 입도, 형상, 조성, 불순물 등의 기초적인 물성을 분석하고, 이를 활용하여 반응기 내부에서 일어날 수 있는 승화 거동을 예측하였다. 종합적인 판단 결과, 재생 분말의 물성은 단결정 성장에 적합 하였고, 이를 이용하여 단결정 성장 실험을 진행하였다. 높이 25 mm, 직경 100 mm 4H-SiC 단결정 잉곳을 다른 다형혼입 없이 성장 시켰다. 동공 결함 밀도는 0.02 ea/cm², 비저항은 0.015~0.020 ohm·cm² 측정되어 상용 수준의 품질을 얻었으나, 실제 소자 적용을 위해서는 전위 결함, 적층 결함과 관련된 추가 분석이 필요하다고 판단된다.