• Title/Summary/Keyword: Indoor inhalation

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Comparative Study of Soil Risk Assessment Models used in Developed Countries (선진국의 토양위해성평가 모델 비교분석 연구)

  • An, Youn-Joo;Baek, Yong-Wook;Lee, Woo-Mi;Jeong, Seung-Woo;Kim, Tae-Seung
    • Journal of Soil and Groundwater Environment
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    • v.12 no.1
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    • pp.53-63
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    • 2007
  • Soil risk assessment models were used to determine the goals of soil remediation and to establish the soil quality standards in developed countries. Recently, Korean Ministry of Environment prepared the guideline for soil risk assessment. Soil risk assessment model applicable to Korean situation will be needed in the near future. In this study, three models for soil risk assessment were extensively compared to suggest the fundamental components that required for the soil risk assessment in Korea. The models considered in this study were CalTOX in the United States, CLEA (Contaminated Land Exposure Assessment) in the United Kingdom, and CSOIL in the Netherlands. The major exposure routes and the intake estimation equations suitable for Korean situation were suggested. The exposure routes suggested were intake of the crops, underground water, indoor outdoor soil ingestion, dust inhalation and a volatile matter inhalation. The equations for intake estimation used in CalTOX and CSOIL seem to be applicable for the calculation of the human intake in Korea.

Evaluation of PM2.5 Exposure Contribution Using a Microenvironmental Model (국소환경 모델을 이용한 초미세먼지(PM2.5) 노출 기여율 평가)

  • Shin, Jihun;Choe, Yongtae;Kim, Dongjun;Min, Gihong;Woo, Jaemin;Kim, Dongjun;Shin, Junghyun;Cho, Mansu;Sung, Kyeonghwa;Lee, Jongdae;Yang, Wonho
    • Journal of Environmental Health Sciences
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    • v.48 no.2
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    • pp.59-65
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    • 2022
  • Background: Since people move through microenvironments rather than staying in one place, they may be exposed to both indoor and outdoor PM2.5 concentrations. Objectives: The aim of this study was to assess the exposure level of each sub-population group and evaluate the contribution rate of the major microenvironments. Methods: Exposure scenarios for sub-population groups were constructed on the basis of a 2019 Time-Use survey and the previous literature. A total of five population groups were classified and researchers wearing MicroPEM simulated monitoring PM2.5 exposure concentrations in real-time over three days. The exposure contribution for each microenvironment were evaluated by multiplying the inhalation rate and the PM2.5 exposure concentration levels. Results: Mean PM2.5 concentrations were 33.0 ㎍/m3 and 22.5 ㎍/m3 in Guro-gu and Wonju, respectively. When the exposure was calculated considering each inhalation rate and concentration, the home showed the highest exposure contribution rate for PM2.5. As for preschool children, it was 90.8% in Guro-gu, 94.1% in Wonju. For students it was 65.3% and 67.3%. For housewives it was 98.2% and 95.8%, and 59.5% and 91.7% for office workers. Both regions had higher exposure to PM2.5 among the elderly compared to other populations, and their PM2.5 exposure contribution rates were 98.3% and 94.1% at home for Guro-gu and Wonju, respectively. Conclusions: The exposure contribution rate could be dependent on time spent in microenvironments. Notably, the contribution rate of exposure to PM2.5 at home was the highest because most people spend the longest time at home. Therefore, microenvironments such as home with a higher contribution rate of exposure to PM2.5 could be managed to upgrade public health.

A Survey on Asbestos Exposure Possibility in Indoor and Outdoor Environments of Childcare Centers (어린이집 실내·외 석면노출 가능성 조사에 관한 연구)

  • Park, Whame;Son, Byeung-Hun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.2
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    • pp.122-129
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    • 2014
  • Objectives: Because of its properties such as resistance to heat, chemicals and corrosion; tensile strength; sound absorption; and affordable price, asbestos has been widely used as a building material, fire resistant and retardant, thermal and heat insulator, soundproofing material, and electrical insulation. Since the prolonged inhalation of asbestos can cause serious illnesses such as lung cancer, mesothelioma, and asbestosis after an incubation period of 20 to 40 years, the mineral was classified as a Group 1 carcinogen by the International Agency for Research on Cancer, an intergovernmental agency forming part of the World Health Organization. Children and infants are more at risk than are adults if they are exposed to carcinogens, due to aweaker immunity that has not yet been fully developed. Most childcare centers are operated all day and children tend to spend a great amount of time in the centers. This is why it is important for them to be systematically isolated from environments that may expose them to asbestos. Materials: In order to understand both indoor and outdoor hazards to which children may have been exposed, the study focused on actual surveys of asbestos used in childcare centers, paying special attention to slate-roofed buildings in the vicinity of the centers. Results: A survey of a total of 211 childcare centers showed that the buildings of 18.1% of the centers contained asbestos, with 60.53% of the material being found in classroom ceilings. "Tex" was the most used material for ceilings, making up 89.47% of all ceilings. An outdoor survey showed that childcare centers in Daegu Metropolitan City had an average of 143 slate-roof buildings within a distance of 1km. Conclusions: Buildings housing mainly toddlers, children, teenagers and others more vulnerable to the toxicity of asbestos are not subject to asbestos investigation by law. A legal and practical basis for asbestos control is required for such buildings. In particular, housing materials which contain asbestos in day care centers require asbestos control. GIS should be used to identify the location of buildings with slate roofing materials in the vicinity of daycare centers in order to gauge toxicity of exposure to asbestos caused by potential asbestos friability possibility in outdoor conditions.

Comparing Physiological Changes in Breathing Conditions during Cognitive Tasks (인지부하 환경에서 호흡방식이 생체신호의 변화에 미치는 영향)

  • Jung, Ju-Yeon;Lee, Yeong-Bae;Park, Hyeon-Mi;Kang, Chang-Ki
    • Science of Emotion and Sensibility
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    • v.25 no.2
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    • pp.79-86
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    • 2022
  • With external air pollution forcing many people indoors, new methods of facilitating healthier indoor life are necessary. This study, therefore, investigates the effects of indoor oxygen concentration and respiration methods on biosignals and cognitive ability. The study included twenty healthy subjects who inhaled air through a mask from a gas delivery system. All subjects were asked to perform three types of breathing (nasal, oral, and oral breathing with high oxygenation) and respond to cognitive stimuli (rest close eye, rest open eye, 1-back and 2-back working memory tasks). The changes in cognitive load according to respiration were analyzed by measuring response time, accuracy, and biosignals to stimuli. The result showed that, in all three respirations, heart rate significantly increased with the increase in cognitive load. Also, in oral respiration, the airway respiration rate significantly increased according to the increase in cognitive load. The change appeared to compensate for insufficient oxygen supply in oral respiration during cognitive activity. Conversely, there was no significant change in airway respiration rate during oral respiration with a high concentration oxygen supply as in nasal respiration. This result suggests that a high concentration oxygen supply might play a role in compensating for insufficient oxygen concentration or inefficient oxygen inhalation, such as oral respiration. Based on the results of this study, a follow-up study is necessary to determine the impact of changes in the autonomic nervous system, such as stress and emotions, to find out more precise and comprehensive effects of oxygen concentration and breathing type.

Human Risk Assessment of Perchloroethylene Considering Multi-media Exposure (다매체 노출을 고려한 Perchloroethylene의 인체위해성평가연구)

  • Seo, Jungkwan;Kim, Taksoo;Jo, Areum;Kim, Pilje;Choi, Kyunghee
    • Journal of Environmental Health Sciences
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    • v.40 no.5
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    • pp.397-406
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    • 2014
  • Objectives: Perchloroethylene (PCE) is a volatile chemical widely used as a solvent in the dry-cleaning and textile processing industries. It was evaluated as Group 2 "probably carcinogenic to humans" by the Integrated Risk Information System (IRIS) of the United State Environmental Protection Agency (U.S. EPA) in 2012. In order to provide a scientific basis for establishing risk management measures for chemicals on the national priority substances list, aggregate risk assessment was conducted for PCE, included in the top-10 substances. Methods: We conducted the investigation and monitoring of PCE exposure (e.g., exposure scenario, detection levels, and exposure factors, etc.) and assessed its multi-media (e.g., outdoor air, indoor air, and ground water) exposure risk with a deterministic and probabilistic approach. Results: In human risk assessment (HRA), the level of human exposure was higher in the younger age group. The exposure level through inhalation at home was the highest among the exposure routes. Outdoor air or uptake of drinking water represented less than 1% of total contributions to PCE exposure. These findings suggested that the level of risk was negligible since the Hazard Index (HI) induced by HRA was below one among all age groups, with a maximum HI value of 0.17 when reasonable maximum exposure was applied. Conclusion: In conclusion, it was suggested that despite low exposure risk, further studies are needed considering main sources, including occupational exposure.

CHLOROFORM IN THE AIR OF INDOOR SWIMMING POOLS AND THE OUTDOOR AIR NEAR THE SWIMMING POOLS IN A CITY OF KOREA (국내 한 도시의 실내 수영장 공기 및 수영장 인근의 실외 공기에서의 클로로포름)

  • 조완근;황영미
    • Journal of Environmental Science International
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    • v.3 no.3
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    • pp.253-261
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    • 1994
  • Chloroform present in the swimming water disinfected with sodium hypochlorite is released to the air of swimming pools. The air chloroform concentrations were measured in two swimming pools A and B which applied both sodium hypochlorite a:d ozone. Thew mean concentrations are 28.0 $\mu\textrm{g}$/m3 and 33.6 $\mu\textrm{g}$/m3in the swimming pools A and B, respectively. On the other hand, the mean water chloroform concentrations in the swimming pools A and B were 23.9 $\mu\textrm{g}$/l and 19.5 $\mu\textrm{g}$/l, respectively. The air chloroform concentrations were lower in the swimming Bools A and B than those reported by previous studies abroad employed the swimming pools which applied sodium hypochlorite only for water disinfection. The water chloroform concentrations were also lower in this study than in the previous studies. The relationship between the air and water chloroform concentrations measured in this study was significant with p=0.002 and Rz=0.42. At similar time to the indoor air sampling, outdoor air samples were collected at two sites near each of the swimming Pools A and B. The mean outdoor air chloroform concentrations near the swiminE Pools A and B were 0.41 $\mu\textrm{g}$/m3 and 0.16 $\mu\textrm{g}$/m3, respectively. The outdoor air chloroform concentrations measured in this study were equal to or lower than those reported by previous studies abroad. 'rho chloroform dose inhaled for a typical one-hour swim was estimated to be 25.9 $\mu\textrm{g}$ per person, corresponding to a specific 0.37 $\mu\textrm{g}$/kg body weight for a reference 70 Kg male adult, while the inhalation dose of chloroform from the outdoor air was estimated to be 5.6 $\mu\textrm{g}$ per person per day, corresponding to a specific 0.08 $\mu\textrm{g}$/Kg/day for the same reference male adult.

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Anti-inflammatory Effects of Inhalation of Injured Starfish Extracts on Formaldehyde Exposure (손상된 불가사리 추출물 흡입이 포름알데히드 노출에 의한 항염증 작용에 미치는 효과)

  • Hwang, Kyung Hee;Chang, Su Chan;Park, Jong Seok;Wahid, Fazli;Kim, You Young
    • Journal of Life Science
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    • v.23 no.4
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    • pp.501-509
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    • 2013
  • Formaldehyde (FA) is widely used in industries, and it is an indoor and outdoor pollutant. Exposure to FA may cause inflammation and respiratory oxidative stress. Studies have demonstrated that FA can cause cancer in animal models. During the regeneration process of injured starfish (Asterina pectinifera), several changes have been observed in the expression of cytokines. In particular, higher TGF-${\beta}1$ expression has been detected in arm cut starfish extract after eight days. The current study was designed to elucidate the in-vitro and the in-vivo pharmacological effects of starfish extract on FA exposure. We investigated the protective effects of intact starfish extract and arm cut starfish extract on an IMR-90 cell line and on mouse lung injury in response to FA exposure. In the presence of FA, inhalation of the arm cut starfish extract was associated with more promising cell proliferation, TNF-${\alpha}$, NF-${\kappa}B$ decrement, and $I{\kappa}-B{\alpha}$ increment. In the experimental group, the pulmonary structure of the arm cut starfish extract-treated group in the presence of FA exposure was similar to the control group, whereas the FA exposure group showed damage to the pulmonary structure. Moreover, the arm cut starfish extracts was more effective than the intact starfish extracts in terms of the expression of TNF-${\alpha}$, NF-${\kappa}B$, $I{\kappa}-B{\alpha}$, and surfactant protein A. The results obtained in this study demonstrate that arm cut starfish extracts are more effective in protecting pulmonary structure and function against FA exposure than intact starfish extracts.

Development of Filtering Sets Composed of Lignocellulosic Fiber-based 3-layers Fiberboard and Traditional Korean Paper for the Purification of Indoor and Outdoor Air Pollutants (리그노셀룰로오스 섬유-기반 3층 섬유판과 한지로 구성된 실내외 대기 오염물질 정화용 필터세트의 개발)

  • Young-kyu Lee;Yeong Seo Choi;Myoung cheol Moon;Jae min So;Ohkyung Kwon;Wonsil Choi;Joon weon Choi;In Yang
    • Korean Chemical Engineering Research
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    • v.62 no.1
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    • pp.87-98
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    • 2024
  • This study was conducted to investigate the efficiency of the filtering sets composed of fiberboards, which were fabricated with lignocellulosic fiber and cork oak bark-based activated carbon (COA), as well as traditional Korean paper handmade from mulberry trees (KP) for the filtration of PM, TVOC and HCHO. Three-layers fiberboards (WRF) were fabricated with wood fiber in its surface layers and recycled fiber/COA in its core layer using a protein-based adhesive with the resin content of 8%. Filtering sets were composed of three WRF and one sheet of KP. Concentrations of PM, TVOC and HCHO generated with the combustion of a incense in a sealed laboratory hood were reduced efficiently with the operation of air-purifier installed the filtering sets. Except for the WRF fabricated with 4%/4% resin contents, other WRF were prepared with 5%/3% and 6%/2% resin contents in surface/core layers, and then the WRF were used with KP for the fabrication of filtering sets. Filtration efficiency of the filtering sets was improved as the core-layer resin content applied in the fabrication of WRF decreased. In addition, filtration efficiency of the WRF-based filtering set fabricated with KP of 25 g/m2 basis weight was higher than that with KP of 45 g/m2 basis weight. Filtering sets composed of three-layers fiberboards (RWF) that recycled fiber and wood fiber/COA were used in its surface and core layers, respectively, and KP-25g showed higher filtration efficiency than those of WRF-based filtering sets. Air-inhalation equipment installed the RWF-based, WRF-based filtering sets and without filtering set were operated in small indoor and large outdoor spaces. Efficiency for filtering PM and TVOC of the RWF-based filtering sets was higher than that of other filtering sets. It is concluded that fiberboard-based filtering sets composed of RWF and KP-25g can be used as a filter for reducing the concentrations of PM and TVOC existed in indoor and outdoor spaces.

DEHP, DEP and DBP Exposure Analysis using Urinary Metabolites of Gyonggi Province University Students

  • Lee, JangWoo;Kho, YoungLim;Kim, SungKyoon;Choi, Kyungho;Hwang, SeongHee;Jeong, Jeeyeon;Kim, Pangyi
    • Journal of Environmental Health Sciences
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    • v.39 no.5
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    • pp.408-417
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    • 2013
  • Objectives: Phthalates are used as plasticizers in polyvinyl chloride (PVC) plastics. As phthalate plasticizers are not chemically bound to the PVC, they can leach, migrate or evaporate into indoor air and atmosphere, foodstuffs, other materials, etc. Therefore, humans are exposed through ingestion, inhalation, and dermal exposure over their entire lifetime, including during intrauterine development. In particular, university students have a great number of opportunities to contact products including phthalates during campus life (food packaging, body care products, cosmetic, lotions, aftershave, perfume etc.). The purpose of this study was to examine levels of phthalate exposure as undergraduate students begin to use pharmaceuticals and personal care products including phthalates. Methods: Phthalate metabolites, mono-ethyl phthalate (MEP), mono-n-butyl phthalate (MnBP), mono-isobutyl phthalate (MiBP), mono-2- ethylhexyl phthalate (MEHP), {(mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP}, and mono-(2-ethlyl-5-oxohexyl) phthalate (MEOHP} were examined. 80 urine samples collected from university students were analyzed using LC/MS/MS(API 4000, Applied Bioscience) with on-line enrichment and columnswitching techniques. This study was carried out at Y university located in Gyonggi Province from 2008 to 2011. Results: The detection limit of phthalate metabolites were 0.03 ng/mL for MEP, 0.11 ng/mL for MnBP, 0.08 ng/mL for MiBP, 0.93 ng/mL for MEHP, 0.19 ng/mL for MEOHP and 0.16ng/mL for MEHHP. MnBP showed the highest urinary levels (median: 31.6 ug/L, 24.8 ug/g creatinine (cr)). Concentrations were also high for MEHHP (median: 24.1 ug/L, 19.0 ug/g cr), followed by MEOHP (median: 22.8 ug/L, 17.9 ug/g cr). In individual cases, the maximum level reached up to 348 ug/L, and 291 ug/g cr, respectively. The urinary and creatinine adjusted levels of MEP were lower than those for DBP and DEHP metabolites, but were higher in 95th percentiles. As a result, the mean daily DEP intake value was 2.3 ${\mu}g/kg$ bw/day, 3.5 ${\mu}g/kg$ bw/day for DEHP and 4.9 ${\mu}g/kg$ bw/day for DBP. Conclusion: These students' phthalate exposure levels were below the international safe level set by the EU, but higher than the 2012 KFDA survey of the age group from 3 to 18.

Lectin Histochemistry on the Effects of Smoking on Glycoconjugates of Rat Sebaceous Glands (흡연이 흰쥐 복부 피지샘의 glycoconjugates에 미치는 영향에 대한 lectin 조직화학)

  • Jo, Un-Bock;Jeong, Gil-Nam
    • Journal of Life Science
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    • v.18 no.11
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    • pp.1543-1550
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    • 2008
  • We studied the effects of smoking, which is one of indoor-environmental pollutants and related to various cancers, on glycoconjugates of rat sebaceous glands with the lectin histochemistry. To investigate the effects of smoking on glycoconjugates, male Sprague-Dawley rats were exposed to tabacco smoke for 10 minutes per day in an inhalation chamber for 1, 2, 3, and 5 days with active and passive exposure. For the structure of sebaceous glands we used PAS reaction, and for the glycoconjugates binding pattern 9 biotinylated lectins (DBA, SBA, PNA, BSL-1, WGA, RCA-1, UEA-1, Con A, and LCA) were used. Some remarkable changes, such as the decrease in the size of sebaceous glandular acini, the destruction of upper portion of sebaceous glands, vacuolation of central portion of sebocytes, and the immature sebaceous glandular acini were seen in the smoke-exposed rats. In the control rats, basal cells were stained with BSL-1, PNA and WGA, but the stronger reaction was founded in BSL-1 binding. Also, sebocytes were stained with PNA, WGA, Con A, BSL-1 and SBA, but stronger reactions were founded in PNA and Con A stainings. Specific changes in the lectin binding patterns were also observed in the smoke-exposed rats. In the basal cells of exposed rats, PNA binding increased, BSL-1 decreased but returned to control level, and WGA disappeared. Plus, immature glandular acini, which were not found in the control rats, were stained PNA, Con A and BSL-1, but the stronger reaction were founded in PNA and Con A binding. In conclusion, it was assumed that the tabacco smoke seriously effected on the structure and glycoconjugates metabolism of sebaceous glands.