• Title/Summary/Keyword: India Development

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Histopathological Study and Expression of Beta-Catenin in Congenital Choledochal Cyst in a Tertiary Care Pediatric Referral Center in South India

  • Rashmi Tresa Philpose;Abdul Aleem Mohammed;Ashrith Reddy Gowni
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.27 no.1
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    • pp.62-70
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    • 2024
  • Purpose: Choledochal cysts are congenital anomalies that occur as localized cystic or fusiform dilatations of the biliary tree. Reflux and stasis of pancreatic enzymes in the biliary duct may relate to the development of intestinal metaplasia which might be an important factor related to the carcinogenesis of choledochal cyst, thus the expression of beta-catenin in the metaplastic epithelium might be associated with malignant transformation of choledochal cyst epithelium. Methods: This study was conducted at a tertiary care pediatric center between October 2014 and March 2017. Forty patients were evaluated for epithelial lining, mural ulceration, fibrosis, inflammation, and metaplasia. Results: Out of 40, 12 cases (30.0%) were the infantile age group and 28 cases (70.0%) were in the classic pediatric group. Ulceration was classified as grade 0 (14 cases, 35.0%), grade 1 (17 cases, 42.5%), or grade 2 (nine cases, 22.5%). Inflammation was classified as grade 0 (2 cases, 5.0%), grade 1 (26 cases, 65.0%), or grade 2 (12 cases, 30.0%). Fibrosis was classified as grade 0 (five cases, 12.5%), grade 1 (11 cases, 27.5%), grade 2 (17 cases, 42.5%), or grade 3 (seven cases, 17.5%). Metaplasia was noted in five (12.5%) out of 40 cases. All choledochal cysts with metaplasia showed beta-catenin nuclear positivity on immunohistochemistry and were followed up. Conclusion: This study emphasizes the importance of detailed histopathological examination and documentation of metaplastic changes. Metaplasia was associated with beta-catenin nuclear positivity. These findings suggest a potential role for beta-catenin as a marker of metaplastic changes in choledochal cysts.

Amblyomma testudinarium Koch, 1844: Discovery and Record in Korea, and Identification and Redescription of Male Tick (Amblyomma testudinarium 진드기의 국내발견기록(國內發見記錄), 종속동정(種屬同定) 및 웅충(雄蟲)에 대한 형태학적(形態學的) 재기술(再記述))

  • Kang, Yung-Bai;Suh, Myung-Deuk;Kim, Yong-Hee;Byun, Si-Yul;Lim, Hi-Ung
    • Korean Journal of Veterinary Research
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    • v.21 no.2
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    • pp.65-72
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    • 1981
  • Amblyomma testudinarium Koch', 1844, previousely known to occur in India, Sri Lanka, Burma, Thailand, Malaysia, Indonesia, Indochina, the Philipines, Taiwan and Japan, is here firstly discovered and recorded in Korea. A male specimen was collected from grazing Frisian cattle of the Dae Weon Farm on Jeju Island by a local veterinary official on the 28th June in 1981. The specimen was examined at the institute of Veterinary Research in Anyang and was identified as A. testudinarium. The morphological characteristics of the male specimen were redescribed. A tota1 of 18 species of ticks belonging to 7 genera, such as, Argas, Amblyomma, Boophilus, Dermaccntor, Haemaphysalis, Hyalomma and Ixodes, has now been recorded to occur in Korea.

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Development Trend of the Reusable Space Launch Vehicle (재사용 우주 발사체 개발 동향)

  • Jeong, Seokgyu;Bae, Jinhyun;Jeong, Gijeong;Koo, Jaye;Yoon, Youngbin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.45 no.12
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    • pp.1069-1075
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    • 2017
  • With the recent development of space technology, the satellite market, especially the small satellite market, is growing globally. As the satellite market continues to grow, the launch vehicle market is also growing, and demand for low-cost launches is increasing. There are a number of options for low-cost launches, including development of engine that uses low-cost propellants, product and transportation cost savings, but the most effective way to reduce launch costs is to reuse the used launch vehicles. USA's Space Shuttle, a famous rocket as manned spacecraft, could be referred as the start of reusable launch vehicle. However, Space Shuttle had limited reusable parts and it was very expensive even though it is a reusable launch vehicle because of its low efficiency. In recent years, aiming at a real reusable launch vehicle, reusable launch vehicle for commercial purposes have been developed around USA's SpaceX and Blue Origin, and re-landing tests were successfully accomplished. In addition, SpaceX successfully did the re-using of first-stage launch vehicle that had been succeeded in re-landing already. In accordance with this trend, countries such as Europe and India are also concentrating on the study of reusable launch vehicles. Including Blue Origin, companies like Virgin Galactic and XCOR in the United States, are also trying to commercialize the same reusable technology as the private manned space tourism. Confirmation of these technology trends is essential, because the re-use technology could change the landscape of the global launch vehicle market.

A Study on the Changing Patterns of the Ancient Buddhist Temples of Korea - Based on the Analysis about Development of View of Buddha-kaya, Change of Status of Stupa and Statue of the Buddha - (한국고대가람 변천양상에 관한 불교사적 고찰 - 불신관의 발전과 불탑 및 불상의 위상변천에 관한 분석을 중심으로 -)

  • Lee, Zu-Hyung;Jang, Suk-Ha
    • Journal of architectural history
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    • v.20 no.1
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    • pp.95-116
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    • 2011
  • It is a true fact that the ancient Buddhist temples of Korea were great, important historical influence revealing the transition and developing stages of all the BUddhist temples in Eastern Asia including China and Japan. Before Mahayana arose within India, the monastery and pagoda were united during the conflict and development of the original Buddhism and pagoda faith. With the arising of Mahayana and the introduction of Buddhist statues, the Buddhist temple and pagoda were in conflict and resulted in separation. With the creation and development of the Mahayana Bodhisattva concept, Hinayana and Mahayana started to show doctrine differences and expressed each others' characteristics relevant to the structure of the temple. As a result, the Buddhist Temple having 1 pagoda spread in China together with Hinayana and Mahayana. The Buddhist temple of Hinayana had its temple and pagoda separated and the Buddhist temple that has a pagoda in front was divided into a form of 1 pagoda and 1 main temple. The temple and pagoda for Mahayana in the form of 1 pagoda and 2 temple, where the main statue of the Buddha may be worshipped from both the left and right hand sides, were separated in the form of 1 pagoda and 3 temples to have its original form again. Mahayana was first introduced into Goguryeo through the routes in the northern region and developed from having 1 pagoda and 2 temples, to having 1 pagoda and 3 temples. China was influenced by the southern regions, which is why Abhidharma was introduced into Baekje. Later on, the importance of Bodhisattva increased and the transition speed of the Buddhist temple having 1 pagoda and 3 temples accelerated, as Buddhism became more popular and as Mahayana flourished. The statue of the Buddha on both sides of the pagoda shall gradually move next to the central temple, and the temple shall form large crowds to not only form a tacit boundary with the pagoda but the expansion of Bodhisattva shall also have a wall or a corridor constructed in between the central, left and right hand side temples to form separate areas, and shall have a pagoda built in front of the temples that worship from both sides. In conclusion, independence shall exist among each Bodhisattva within the Buddhist temple, and the status of the pagoda shall fall and appear as the pagoda on both sides in front of the main Buddha statue.

The Influence Factors of China's Cross-border E-commerce Export Trade Using Gravity Model

  • Jing Han;Taehee Lee
    • Journal of Korea Trade
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    • v.26 no.5
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    • pp.56-75
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    • 2022
  • Purpose - This study examines the influencing factors of China's cross-border e-commerce exports in the context of the current situation and trends of China's cross-border e-commerce development. Through an improved trade gravity model, it provides more in-depth research and constructive opinions on the development of cross-border e-commerce in China. In this paper, factors such as consumption gap, volume of trade frictions, number of tourists, Internet usage and trade openness are added to the formula of the traditional trade gravity model in the improved trade gravity model to examine the influencing factors on China's cross-border e-commerce exports. Design/methodology - According to the empirical analysis, China's cross-border e-commerce exports to ten countries are used as dependent variables, and consumption gap, trade friction volume, trade distance, trade openness and number of Internet users are taken as independent variables. Regression analysis is conducted through a modified gravity model to test whether the hypotheses hold. Findings - The analysis shows that the hypothesis that China's cross-border e-commerce exports are influenced by trade openness, trade distance, consumption gap between trade parties, and the number of Internet users in the importing country is supported by these four hypotheses, but not all independent variables have an impact on them. Specifically, the number of travelers, trade frictions do not have an impact on China's cross-border e-commerce. That is to say, trade friction between China and the United States and political issues such as China-India and China-Japan territorial disputes that emerged before do not affect the development of cross-border e-commerce in China. Originality/value - The analysis shows that the factors influencing China's cross-border e-commerce exports are the trade openness of the importing country, the trade distance, the number of Internet users in the importing country, and the consumption gap between the two sides of the trade. The trade openness and the number of Internet users positively contribute to China's cross-border e-commerce, while the consumption gap and trade distance are negatively related to them. And the analysis found that the Sino-US trade war and the Sino-Indian territorial disputes and other trade frictions to China's cross-border e-commerce exports did not have a substantial impact.

Current Pediatric Endoscopy Training Situation in the Asia-Pacific Region: A Collaborative Survey by the Asian Pan-Pacific Society for Pediatric Gastroenterology, Hepatology and Nutrition Endoscopy Scientific Subcommittee

  • Nuthapong Ukarapol;Narumon Tanatip;Ajay Sharma;Maribel Vitug-Sales;Robert Nicholas Lopez;Rohan Malik;Ruey Terng Ng;Shuichiro Umetsu;Songpon Getsuwan;Tak Yau Stephen Lui;Yao-Jong Yang;Yeoun Joo Lee;Katsuhiro Arai;Kyung Mo Kim; APPSPGHAN Endoscopy Scientific Subcommittee
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.27 no.4
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    • pp.258-265
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    • 2024
  • Purpose: To date, there is no region-specific guideline for pediatric endoscopy training. This study aimed to illustrate the current status of pediatric endoscopy training in Asia-Pacific region and identify opportunities for improvement. Methods: A cross-sectional survey, using a standardized electronic questionnaire, was conducted among medical schools in the Asia-Pacific region in January 2024. Results: A total of 57 medical centers in 12 countries offering formal Pediatric Gastroenterology training programs participated in this regional survey. More than 75% of the centers had an average case load of <10 cases per week for both diagnostic and therapeutic endoscopies. Only 36% of the study programs employed competency-based outcomes for program development, whereas nearly half (48%) used volume-based curricula. Foreign body retrieval, polypectomy, percutaneous endoscopic gastrostomy, and esophageal variceal hemostasis, that is, sclerotherapy or band ligation (endoscopic variceal sclerotherapy and endoscopic variceal ligation), comprised the top four priorities that the trainees should acquire in the autonomous stage (unconscious) of competence. Regarding the learning environment, only 31.5% provided formal hands-on workshops/simulation training. The direct observation of procedural skills was the most commonly used assessment method. The application of a quality assurance (QA) system in both educational and patient care (Pediatric Endoscopy Quality Improvement Network) aspects was present in only 28% and 17% of the centers, respectively. Conclusion: Compared with Western academic societies, the limited availability of cases remains a major concern. To close this gap, simulation and adult endoscopy training are essential. The implementation of reliable and valid assessment tools and QA systems can lead to significant development in future programs.

Space Development and Law in Asia (아시아의 우주개발과 우주법)

  • Cho, Hong-Je
    • The Korean Journal of Air & Space Law and Policy
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    • v.28 no.2
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    • pp.349-384
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    • 2013
  • The Sputnik 1 launching in 1957 made the world recognize the necessity of international regulations on space development and activities in outer space. The United Nations established COPUOS the very next year, and adopted the mandate to examine legal issues concerning the peaceful uses of outer space. At the time, the military sector of the U.S.A. and the Soviet Union were in charge of the space development and they were not welcomed to discuss the prohibition of the military uses of outer space at the legal section in the COPUOS. Although both countries had common interests in securing the freedom of military uses in outer space. As the social and economic benefits derived from space activities have become more apparent, civil expenditures on space activities have continued to increase in several countries. Virtually all new spacefaring states explicitly place a priority on space-based applications to support social and economic development. Such space applications as satellite navigation and Earth imaging are core elements of almost every existing civil space program. Likewise, Moon exploration continues to be a priority for such established spacefaring states as China, Russia, India, and Japan. Recently, Companies that manufacture satellites and ground equipment have also seen significant growth. On 25 February 2012 China successfully launched the eleventh satellite for its indigenous global navigation and positioning satellite system, Beidou. Civil space activities began to grow in China when they were allocated to the China Great Wall Industry Corporation in 1986. China Aerospace Corporation was established in 1993, followed by the development of the China National Space Administration. In Japan civil space was initially coordinated by the National Space Activities Council formed in 1960. Most of the work was performed by the Institute of Space and Aeronautical Science of the University of Tokyo, the National Aerospace Laboratory, and, most importantly, the National Space Development Agency. In 2003 all this work was assumed by the Japanese Aerospace Exploration Agency(JAXA). Japan eases restrictions on military space development. On 20 June 2012 Japan passed the Partial Revision of the Cabinet Establishment Act, which restructured the authority to regulate Japanese space policy and budget, including the governance of the JAXA. Under this legislation, the Space Activities Commission of the Ministry of Education, Culture, Sports, Science, and Technology, which was responsible for the development of Japanese space program, will be abolished. Regulation of space policy and budget will be handed over to the Space Strategy Headquarter formed under the Prime Minister's Cabinet. Space Strategy will be supported by a Consultative Policy Commission as an academics and independent observers. By revoking Article 4 (Objectives of the Agency) of a law that previously governed JAXA and mandated the development of space programs for "peaceful purposes only," the new legislation demonstrates consistency with Article 2 of the 2008 Basic Space Law. In conformity with the principles laid down in the 1967 Outer Space Treaty JAXA is now free to pursue the non-aggressive military use of space. New legislation is the culmination of a decade-long process that sought ways to "leverage Japan's space development programs and technologies for security purposes, to bolster the nation's defenses in the face of increased tensions in East Asia." In this connection it would also be very important and necessary to create an Asian Space Agency(ASA) for strengthening cooperation within the Asian space community towards joint undertakings.

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Study on GNSS Constellation Combination to Improve the Current and Future Multi-GNSS Navigation Performance

  • Seok, Hyojeong;Yoon, Donghwan;Lim, Cheol Soon;Park, Byungwoon;Seo, Seung-Woo;Park, Jun-Pyo
    • Journal of Positioning, Navigation, and Timing
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    • v.4 no.2
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    • pp.43-55
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    • 2015
  • In the case of satellite navigation positioning, the shielding of satellite signals is determined by the environment of the region at which a user is located, and the navigation performance is determined accordingly. The accuracy of user position determination varies depending on the dilution of precision (DOP) which is a measuring index for the geometric characteristics of visible satellites; and if the minimum visible satellites are not secured, position determination is impossible. Currently, the GLObal NAvigation Satellite system (GLONASS) of Russia is used to supplement the navigation performance of the Global Positioning System (GPS) in regions where GPS cannot be used. In addition, the European Satellite Navigation System (Galileo) of the European Union, the Chinese Satellite Navigation System (BeiDou) of China, the Quasi-Zenith Satellite System (QZSS) of Japan, and the Indian Regional Navigation Satellite System (IRNSS) of India are aimed to achieve the full operational capability (FOC) operation of the navigation system. Thus, the number of satellites available for navigation would rapidly increase, particularly in the Asian region; and when integrated navigation is performed, the improvement of navigation performance is expected to be much larger than that in other regions. To secure a stable and prompt position solution, GPS-GLONASS integrated navigation is generally performed at present. However, as available satellite navigation systems have been diversified, finding the minimum satellite constellation combination to obtain the best navigation performance has recently become an issue. For this purpose, it is necessary to examine and predict the navigation performance that could be obtained by the addition of the third satellite navigation system in addition to GPS-GLONASS. In this study, the current status of the integrated navigation performance for various satellite constellation combinations was analyzed based on 2014, and the navigation performance in 2020 was predicted based on the FOC plan of the satellite navigation system for each country. For this prediction, the orbital elements and nominal almanac data of satellite navigation systems that can be observed in the Korean Peninsula were organized, and the minimum elevation angle expecting signal shielding was established based on Matlab and the performance was predicted in terms of DOP. In the case of integrated navigation, a time offset determination algorithm needs to be considered in order to estimate the clock error between navigation systems, and it was analyzed using two kinds of methods: a satellite navigation message based estimation method and a receiver based method where a user directly performs estimation. This simulation is expected to be used as an index for the establishment of the minimum satellite constellation for obtaining the best navigation performance.

Growth and Development of the Academic Societies and Animal Production in Korea, China and Asia over the Last 50 Years

  • Han, In K.;Ha, Jong K.;Lee, J.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.6
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    • pp.906-914
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    • 2009
  • The Korean Society of Animal Science (KSAS) was officially born on October 8, 1956 under the leadership of Professor Sang W. Yun of Seoul National University, Seoul, Korea a few years after the end of the Korean War. At that time, there were 0.9 million Korean native cattle, 1.3 million pigs and 8.9 million chickens in Korea. Per capita income for Korea (US$ 66) or China (US$ 59) was about 10% of Asian's average income (US$ 513) in 1956. Korea produced less than 0.2 million M/T of formula feed and consumed 6.1 kg/person/year of animal products. One could say that Korea was an example of an under-developed country in the world. Although the first issue of the Proceedings of the KSAS was published on October 28, 1958, regular quarterly journals of the KSAS were not published until March 1, 1969. Major activities other than publishing its journal were: holding an annual meeting and/or scientific forum at national or international level. The Asian-Australasian Association of Animal Production Societies (AAAP) was founded on September 1, 1980 at Kuala Lumpur, Malaysia with founding members from Australia, Indonesia, Japan, Korea, Malaysia, NZ, Philippines and Thailand. Thirteen AAAP Animal Science Congresses have been held in its 28 year history. Hosting countries were Malaysia (1980), Philippines (1982), Korea (1985), NZ (1987), Taiwan (1990), Thailand (1992), Indonesia (1994), Japan (1996), Australia (2000), India (2002), Malaysia (2004), Korea (2006) and Vietnam(2008). In 1988, significant progress of the AAAP was made by creating an official English journal of the AAAP entitled "Asian-Australasian Journal of Animal Sciences (AJAS)" under the initiative of the KSAS. This journal is now published monthly and distributed to more than 50 countries in the AAAP region and the world. It should be mentioned that the KSAS was able to successfully host the $3^{rd}$ AAAP Animal Science Congress in 1985 and the 12th in 2006, as well as the $8^{th}$ WCAP in 1998. During the last 50 years of KSAS history, per capita income of Korea increased to US$ 17,690 (268 fold), formula feed production increased to 15 million M/T (97 fold) and consumption of animal products increased to 105 kg/person/year (17 fold). Cattle, pig and chicken numbers also increased to 2.5 million (2.8 fold), 9 million (7.4 fold) and 119 million (13 fold). This trend was also found for China and Asia, even if the rate of growth was slightly lower than that of Korea. It is expected that a similar rate of growth in economics, animal numbers, formula feed production and animal protein intake will likely be achieved by other Asian countries in the $21^{st}$ century with somewhat lower rate of development than that of Korea.

Research and Development Trends of a Hypersonic Glide Vehicle (HGV) (극초음속 활공 비행체(HGV)의 연구개발 동향)

  • Hwang, Ki-Young;Huh, Hwanil
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.48 no.9
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    • pp.731-743
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    • 2020
  • The hypersonic glide vehicle ascends to a high altitude by a rocket booster, separates it from the booster, and glides at a hypersonic speed of Mach 5 or higher at an altitude of about 30~70 km, changing its direction in the atmosphere. Since it moves on an unpredictable flight path rather than a parabolic trajectory, it is difficult to intercept with current missile defense systems. The U.S. conducted HTV-2 and AHW flight tests in the early 2010s to confirm the possibility of hypersonic gliding flights, and recently it has been developing hypersonic glide vehicle systems such as LRHW and ARRW. China has conducted several flight tests of the DF-ZF (WU-14) glide vehicle since 2014 and has been operating it with DF-17 missiles. Russia has conducted hypersonic glide vehicle research since the former Soviet Union, but it has repeatedly failed, and recently it has been successfully tested with the Avangard (Yu-71) glide vehicle mounted on the SS-19 ICBM. In this paper, the characteristics, flight test cases, and development trends of hypersonic glide vehicles developed or currently being developed in the United States, China, Russia, Japan, India, and Europe are reviewed and summarized.