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Assessment of Hydroureteronephrosis in Children Using Diuretic Radionuclide Ureterography (동위원소 이뇨 요관그람을 이용한 소아 요관폐쇄의 평가)

  • Kim, Jong-Ho;Lee, Dong-Soo;Kwark, Cheol-Eun;Lee, Kyung-Han;Choi, Chang-Woon;Chung, June-Key;Lee, Myung-Chul;Koh, Chang-Soon;Choi, Yong;Choi, Hwang
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.1
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    • pp.75-84
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    • 1994
  • The need for assessment of ureteric function in the patient with an obviousely dilated ureter has increased particularly with the added spectrum of asymptomatic patients presenting with hydrone-phrosis and hydroureter on antenatal and perinatal ultrasound. To assess the influence of ureteral status on kidney washout during $^{99m}Tc$-DTPA diuretic renography, ureteral images were reviewed in 80 children referred for hydronephrosis. A scintigraphically abnormal ureter was defined as an intense and continuous image of > 10 min during diuretic renography. Out of them, a total of 16 nephroureteral systems in 12 children with scintigraphically abnormal ureter were analyzed. A diuretic washout index using response half time (t1/2) by linear fitting after lasix injection, was determined on renal (Kt1/2) and ureteral (Ut1/2) curves (diuretic renogram vs. diuretic ureterogram). Diuretic ureterogram curve patterns corresponding to normal (type I), obstructive (II) and non-obstructive (III) cases were described. Compared with X-ray data, diuretic renography was highly sensitive (88%) and specific (99%) for detecting any ureteral abnormality. Despite an obstructive Kt1/2 (>20 min), no patient with an abnormal ureter underwent therapy at the ureteropelvic junction because the hydronephrosis regressed after surgery at the lower level. Our data indicate that the abnormal ureter findings during diuretic renography have to be recognized before therapy for children with hydeonephrosis.

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Application Cases of Test Construction of Hydro-Seeding Measures on the Slopes Along the National Road Between Gamchon and Yaechon (감천예천구간 국도비탈면 종자뿜어붙이기 시험시공 적용사례)

  • Jeon, Gi-Seong;Woo, Kyung-Jin
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.10 no.6
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    • pp.139-151
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    • 2007
  • To protect the surface of ground-cutting slopes and ground-raised slopes and to recover environment-friendly slopes at the national road expansion construction between Gamchon and Yaechon, test-construction work was done using several modes of hydro-seeding measures to select a suitable construction method through the field survey; the results were as follows : As a result of survey on physio-chemical characteristics of soil, the average soil inclination on ground-raised slopes was from 4.73 mm to 5.37 mm; the average soil acidity was from pH 6.47 to 6.73; the average soil humidity was within the scope of 0.57~1.70 %,; the average soil inclination on ground-cutting slopes was 9.17~10.43mm; the average soil acidity was pH 6.67~6.77 and the average soil humidity was within the scope of 0.53~1.27 %; considered overall, they showed generally satisfactory base materials for plant breeding. As a result of the number of sprouting individuals, the average sprouting number of individuals on test spots executed by Coir net with Seed spray construction methods and the average number of sprouting individuals on other test spots executed by furrow-digging with Seed spray and Straw mat-mulching measures were 1,172 number of per square meter and 970 number of per square meter respectively; thus they showed higher numerical value comparing with other test spots. Likewise, the average number of sprouting individuals on test spots of the ground-cutting slopes executed by Coir net with Seed spray method and the average number of sprouting individuals on other test spot executed by furrow-digger with Seed spray and Straw mat-mulching measures were found to be 1,107 number of per square meter and 1,105 number of per square meter respectively, whose numerical value showed rather higher other test spots. As a result of a survey on living plants' breeding index [dried weight], the weight in dried state on test spots executed by Coir net with Seed spray method and other test spots executed by furrow-digger with Seed spray and Straw mat-mulching measures on both ground-raised and ground-cutting slopes was found to be higher and showed similar characteristics statistically. As a result of survey on the surface-covering degree of ground-raised slopes, nine weeks after test construction, test spots executed by Coir net with Seed spray method and other test spots executed by furrow-digger with Seed spray and Straw mat-mulching measures showed commonly more than 70% of surface-covering degree, but other test spots showed only below 35% of surface covering degree; especially in case of test spots by Verdvol seed spray measures, they showed 10% of the lowest surface-covering. Surface-covering degree on the test spot of ground-cutting slopes nine weeks after test construction showed more than 75% both executed by Coir net with Seed spray construction method and executed by furrow-digger with Seed spray and Straw mat-mulching measures. As a result of survey on appearing plants on the test spots, there dominates Eragrostis curvula both on ground-raised slopes and on ground-cutting slopes with other seeding plant life's lower breeding and there appear intruders, such as Setaria viridis Beauv, Digitaria sanguinalis Scop, and Chenopodium album var.centrorubrum Makino. As for water-borne excavation and soil's washing-away on the slopes, there happened less washing-away and water-borne excavation with good breeding of plant life on test spots executed both by Coir net with Seed spray construction method and by furrow-digger with Seed spray and Straw mat-mulching measures, but there happened much more soil's washing-away along with water-home excavation at the test spot executed by Seed spray with measures. After the research results of test construction sites are examined overall, it's presumed that furrow-digger with Seed spray and Straw mat-mulching measures [interval between lines is 40cm, 5cm in depth] will be preferred to prevent erosion and water-home excavation of slopes located within the construction sites.

Immunohistochemical Analysis for the Expression of p27, CDK4, and Uteroglobin in Resected Non-small Cell Lung Cancer (수술로 절제된 비소세포폐암에서 세포주기와 관련된 p27, CDK4, Uteroglobin의 발현에 관한 면역조직학적 분석)

  • Baek, Man-Sun;Hong, Seok-Gyun;Hong, Hyun-Ju;Um, Sang-Won;Lee, Kye-Young;Kim, Woo-Ho;Lee, Choon-Taek;Yoo, Chul-Gyu;Han, Sung-Koo;Shim, Young-Soo;Kim, Young-Whan
    • Tuberculosis and Respiratory Diseases
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    • v.53 no.3
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    • pp.253-264
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    • 2002
  • Background : It has been reported that the expression of protein which influences on the cell cycle is significantly involved in the development, progress, treatment response, and survival of cancer, and also that the degree of expression of p27 and CDK4 is related to the prognosis. Recent research has revealed that uteroglobin, tumor suppressor gene, is related to cell cycle. This study is focused on the relations between expression of proteins related to cell cycle and clinical index of and survival of NSCLC. Methods : We examined immunohistochemically specimens of 110 surgically resected NSCLCs for expression of p27, CDK, Uteroglobin. Tissue array slide were obtained from 110 surgically resected NSCLCs. Immunohistochemical staining was performed by immuno-peroxidase technique using avidin-biotinylated horseradish peroxidase complex. Results : In 110 patients with resected NSCLCs, the ratio of male to female was 87:13, the median age was $56.43{\pm}9.41$ yrs. The positive staining of p27 was detected in 75% of the cases. A non-statistically significant trend toward increased p27 expression was observed in smoker and squamous cell cancer. The positive staining of CDK4 was detected in 89%, which was the highest expression of protein among 3 types. The survival ratio of CDK4 negative staining group was higher than that of positive staining group, which was significant diffrernce(P<0.05). There was no association between p27 or uteroglobin expression and survival. Conclusion : The expression degree of CDK4 is related to the prognosis. This findings suggests that the measurement of CDK4 may be useful in identifying patient at high risk for disease recurrence and survival.

Development of a TBM Advance Rate Model and Its Field Application Based on Full-Scale Shield TBM Tunneling Tests in 70 MPa of Artificial Rock Mass (70 MPa급 인공암반 내 실대형 쉴드TBM 굴진실험을 통한 굴진율 모델 및 활용방안 제안)

  • Kim, Jungjoo;Kim, Kyoungyul;Ryu, Heehwan;Hwan, Jung Ju;Hong, Sungyun;Jo, Seonah;Bae, Dusan
    • KEPCO Journal on Electric Power and Energy
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    • v.6 no.3
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    • pp.305-313
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    • 2020
  • The use of cable tunnels for electric power transmission as well as their construction in difficult conditions such as in subsea terrains and large overburden areas has increased. So, in order to efficiently operate the small diameter shield TBM (Tunnel Boring Machine), the estimation of advance rate and development of a design model is necessary. However, due to limited scope of survey and face mapping, it is very difficult to match the rock mass characteristics and TBM operational data in order to achieve their mutual relationships and to develop an advance rate model. Also, the working mechanism of previously utilized linear cutting machine is slightly different than the real excavation mechanism owing to the penetration of a number of disc cutters taking place at the same time in the rock mass in conjunction with rotation of the cutterhead. So, in order to suggest the advance rate and machine design models for small diameter TBMs, an EPB (Earth Pressure Balance) shield TBM having 3.54 m diameter cutterhead was manufactured and 19 cases of full-scale tunneling tests were performed each in 87.5 ㎥ volume of artificial rock mass. The relationships between advance rate and machine data were effectively analyzed by performing the tests in homogeneous rock mass with 70 MPa uniaxial compressive strength according to the TBM operational parameters such as thrust force and RPM of cutterhead. The utilization of the recorded penetration depth and torque values in the development of models is more accurate and realistic since they were derived through real excavation mechanism. The relationships between normal force on single disc cutter and penetration depth as well as between normal force and rolling force were suggested in this study. The prediction of advance rate and design of TBM can be performed in rock mass having 70 MPa strength using these relationships. An effort was made to improve the application of the developed model by applying the FPI (Field Penetration Index) concept which can overcome the limitation of 100% RQD (Rock Quality Designation) in artificial rock mass.

A Template-based Interactive University Timetabling Support System (템플릿 기반의 상호대화형 전공강의시간표 작성지원시스템)

  • Chang, Yong-Sik;Jeong, Ye-Won
    • Journal of Intelligence and Information Systems
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    • v.16 no.3
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    • pp.121-145
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    • 2010
  • University timetabling depending on the educational environments of universities is an NP-hard problem that the amount of computation required to find solutions increases exponentially with the problem size. For many years, there have been lots of studies on university timetabling from the necessity of automatic timetable generation for students' convenience and effective lesson, and for the effective allocation of subjects, lecturers, and classrooms. Timetables are classified into a course timetable and an examination timetable. This study focuses on the former. In general, a course timetable for liberal arts is scheduled by the office of academic affairs and a course timetable for major subjects is scheduled by each department of a university. We found several problems from the analysis of current course timetabling in departments. First, it is time-consuming and inefficient for each department to do the routine and repetitive timetabling work manually. Second, many classes are concentrated into several time slots in a timetable. This tendency decreases the effectiveness of students' classes. Third, several major subjects might overlap some required subjects in liberal arts at the same time slots in the timetable. In this case, it is required that students should choose only one from the overlapped subjects. Fourth, many subjects are lectured by same lecturers every year and most of lecturers prefer the same time slots for the subjects compared with last year. This means that it will be helpful if departments reuse the previous timetables. To solve such problems and support the effective course timetabling in each department, this study proposes a university timetabling support system based on two phases. In the first phase, each department generates a timetable template from the most similar timetable case, which is based on case-based reasoning. In the second phase, the department schedules a timetable with the help of interactive user interface under the timetabling criteria, which is based on rule-based approach. This study provides the illustrations of Hanshin University. We classified timetabling criteria into intrinsic and extrinsic criteria. In intrinsic criteria, there are three criteria related to lecturer, class, and classroom which are all hard constraints. In extrinsic criteria, there are four criteria related to 'the numbers of lesson hours' by the lecturer, 'prohibition of lecture allocation to specific day-hours' for committee members, 'the number of subjects in the same day-hour,' and 'the use of common classrooms.' In 'the numbers of lesson hours' by the lecturer, there are three kinds of criteria : 'minimum number of lesson hours per week,' 'maximum number of lesson hours per week,' 'maximum number of lesson hours per day.' Extrinsic criteria are also all hard constraints except for 'minimum number of lesson hours per week' considered as a soft constraint. In addition, we proposed two indices for measuring similarities between subjects of current semester and subjects of the previous timetables, and for evaluating distribution degrees of a scheduled timetable. Similarity is measured by comparison of two attributes-subject name and its lecturer-between current semester and a previous semester. The index of distribution degree, based on information entropy, indicates a distribution of subjects in the timetable. To show this study's viability, we implemented a prototype system and performed experiments with the real data of Hanshin University. Average similarity from the most similar cases of all departments was estimated as 41.72%. It means that a timetable template generated from the most similar case will be helpful. Through sensitivity analysis, the result shows that distribution degree will increase if we set 'the number of subjects in the same day-hour' to more than 90%.

Analysis of extreme cases of climate change impact on watershed hydrology and flow duration in Geum river basin using SWAT and STARDEX (SWAT과 STARDEX를 이용한 극한 기후변화 사상에 따른 금강유역의 수문 및 유황분석)

  • Kim, Yong Won;Lee, Ji Wan;Kim, Seong Joon
    • Journal of Korea Water Resources Association
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    • v.51 no.10
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    • pp.905-916
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    • 2018
  • The purpose of this study is to evaluate the climate change impact on watershed hydrology and flow duration in Geum River basin ($9,645.5km^2$) especially by extreme scenarios. The rainfall related extreme index, STARDEX (STAtistical and Regional dynamical Downscaling of EXtremes) was adopted to select the future extreme scenario from the 10 GCMs with RCP 8.5 scenarios by four projection periods (Historical: 1975~2005, 2020s: 2011~2040, 2050s: 2041~2070, 2080s: 2071~2100). As a result, the 5 scenarios of wet (CESM1-BGC and HadGEM2-ES), normal (MPI-ESM-MR), and dry (INM-CM4 and FGOALS-s2) were selected and applied to SWAT (Soil and Water Assessment Tool) hydrological model. The wet scenarios showed big differences comparing with the normal scenario in 2080s period. The 2080s evapotranspiration (ET) of wet scenarios varied from -3.2 to +3.1 mm, the 2080s total runoff (TR) varied from +5.5 to +128.4 mm. The dry scenarios showed big differences comparing with the normal scenario in 2020s period. The 2020s ET for dry scenarios varied from -16.8 to -13.3 mm and the TR varied from -264.0 to -132.3 mm respectively. For the flow duration change, the CFR (coefficient of flow regime, Q10/Q355) was altered from +4.2 to +10.5 for 2080s wet scenarios and from +1.7 to +2.6 for 2020s dry scenarios. As a result of the flow duration analysis according to the change of the hydrological factors of the Geum River basin applying the extreme climate change scenario, INM-CM4 showed suitable scenario to show extreme dry condition and FGOALS-s2 showed suitable scenario for the analysis of the drought condition with large flow duration variability. HadGEM2-ES was evaluated as a scenario that can be used for maximum flow analysis because the flow duration variability was small and CESM1-BGC was evaluated as a scenario that can be applied to the case of extreme flood analysis with large flow duration variability.

Etiology and Clinical Features of Acute Bacterial Gastroenteritis in Children Mananged at a Secondary Hospital (일개 이차 병원에서 치료한 소아 급성 세균성 위장염 원인 및 특징)

  • Kim, Sung Yoon;Kim, Hyun-Jung;Shin, Eun Hye;Eun, Byung Wook;Ahn, Young Min;Song, Mi Ok
    • Pediatric Infection and Vaccine
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    • v.24 no.2
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    • pp.95-101
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    • 2017
  • Purpose: Acute bacterial gastroenteritis (ABG) can cause more severe symptoms than acute viral gastroenteritis in children. This study was aimed at determining the etiologic trends and to examine the clinical characteristics of ABG in children. Methods: We sent stool samples from the children with acute gastroenteritis who were treated at a secondary hospital located in Seoul, Korea between January 2011 and December 2014 to Seoul Metropolitan Government Research Institute of Public Health and Environment to find the causative organisms. Clinical characteristics of patient were analyzed through a medical records review. Results: Out of 664 stool samples, 183 (27.6%) yielded bacterial pathogens. Staphylococcus aureus was the most common bacterial pathogen, found in 72 cases (39.3%), even though it was only tested for since 2012. The monthly isolation rate was the highest (24.6%) in August. The isolation rate of Campylobacter spp. by patient's age group was high (16.7%) in the 12- to 18-year-age group (P=0.04). In patients with bloody stool, Campylobacter spp. was the most commonly isolated (31.0%, P=0.04). When comparing C-reactive protein, the Salmonella spp.- or Campylobacter spp.-isolated group showed higher values than the S. aureus- or pathogenic Escherichia coli-isolated group ($5.7{\pm}0.6mg/dL$ vs. $2.1{\pm}0.3mg/dL$, P<0.01). Conclusions: S. aureus, Salmonella spp., pathogenic E. coli, and Campylobacter spp. were important pathogens of ABG among children. Considering the differences in pathogens found according to age, a clinical symptom and inflammation index might be helpful in assuming the causative organism.

A Study on Development and Prospects of Archival Finding Aids (기록 검색도구의 발전과 전망)

  • Seol, Moon-Won
    • The Korean Journal of Archival Studies
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    • no.23
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    • pp.3-43
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    • 2010
  • Finding aids are tools which facilitate to locate and understand archives and records. Traditionally there are two types of archival finding aids: vertical and horizontal. Vertical finding aids such as inventories have multi-level descriptions based on provenance, while horizontal ones such as catalogs and index are tools to guide to the vertical finding aids based on the subject. In the web environment, traditional finding aids are evolving into more dynamic forms. Respecting the principles of provenance and original order, vertical finding aids are changing to multi-entity structures with development of ISAD(G), ISAAR(CPF) and ISDF as standards for describing each entity. However, vertical finding aids can be too difficult, complicated, and boring for many users, who are accustomed to the easy and exciting searching tools in the internet world. Complementing them, new types of finding aids are appearing to provide easy, interesting, and extensive access channels. This study investigates the development and limitation of vertical finding aids, and the recent trend of evolving new finding aids complementing the vertical ones. The study finds three new trends of finding aid development. They are (i) mixture, (ii) integration, and (iii) openness. In recent days, certain finding aids are mixed with stories and others provide integrated searches for the collections of various heritage institutions. There are cases for experimenting user participation in the development of finding aids using Web 2.0 applications. These new types of finding aids can also cause some problems such as decontextualised description and prejudices, especially in the case of mixed finding aids and quality control of user contributed annotations and comments. To solve these problems, the present paper suggests to strengthen the infrastructure of vertical finding aids and to connect them with various new ones and to facilitate interactions with users of finding aids. It is hoped that the present paper will provide impetus for archives including the National Archives of Korea to set up and evaluate the development strategies for archival finding aids.

Very short-term rainfall prediction based on radar image learning using deep neural network (심층신경망을 이용한 레이더 영상 학습 기반 초단시간 강우예측)

  • Yoon, Seongsim;Park, Heeseong;Shin, Hongjoon
    • Journal of Korea Water Resources Association
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    • v.53 no.12
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    • pp.1159-1172
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    • 2020
  • This study applied deep convolution neural network based on U-Net and SegNet using long period weather radar data to very short-term rainfall prediction. And the results were compared and evaluated with the translation model. For training and validation of deep neural network, Mt. Gwanak and Mt. Gwangdeoksan radar data were collected from 2010 to 2016 and converted to a gray-scale image file in an HDF5 format with a 1km spatial resolution. The deep neural network model was trained to predict precipitation after 10 minutes by using the four consecutive radar image data, and the recursive method of repeating forecasts was applied to carry out lead time 60 minutes with the pretrained deep neural network model. To evaluate the performance of deep neural network prediction model, 24 rain cases in 2017 were forecast for rainfall up to 60 minutes in advance. As a result of evaluating the predicted performance by calculating the mean absolute error (MAE) and critical success index (CSI) at the threshold of 0.1, 1, and 5 mm/hr, the deep neural network model showed better performance in the case of rainfall threshold of 0.1, 1 mm/hr in terms of MAE, and showed better performance than the translation model for lead time 50 minutes in terms of CSI. In particular, although the deep neural network prediction model performed generally better than the translation model for weak rainfall of 5 mm/hr or less, the deep neural network prediction model had limitations in predicting distinct precipitation characteristics of high intensity as a result of the evaluation of threshold of 5 mm/hr. The longer lead time, the spatial smoothness increase with lead time thereby reducing the accuracy of rainfall prediction The translation model turned out to be superior in predicting the exceedance of higher intensity thresholds (> 5 mm/hr) because it preserves distinct precipitation characteristics, but the rainfall position tends to shift incorrectly. This study are expected to be helpful for the improvement of radar rainfall prediction model using deep neural networks in the future. In addition, the massive weather radar data established in this study will be provided through open repositories for future use in subsequent studies.

Numerical analysis of morphological changes by opening gates of Sejong Weir (보 개방에 의한 하도의 지형변화 과정 수치모의 분석(세종보를 중심으로))

  • Jang, Chang-Lae;Baek, Tae Hyo;Kang, Taeun;Ock, Giyoung
    • Journal of Korea Water Resources Association
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    • v.54 no.8
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    • pp.629-641
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    • 2021
  • In this study, a two-dimensional numerical model (Nays2DH) was applied to analyze the process of morphological changes in the river channel bed depending on the changes in the amount of flooding after fully opening the Sejong weir, which was constructed upstream of the Geum River. For this, numerical simulations were performed by assuming the flow conditions, such as a non-uniform flow (NF), unsteady flows (single flood event, SF), and a continuous flood event (CF). Here, in the cases of the SF and CF, the normalized hydrograph was calculated from real flood events, and then the hydrograph was reconfigured by the peak flow discharge according to the scenario, and then it was employed as the flow discharge at the upstream boundary condition. In this study, to quantitatively evaluate the morphological changes, we analyzed the time changes in the bed deformation the bed relief index (BRI), and we compared the aerial photographs of the study area and the numerical simulation results. As simulation results of the NF, when the steady flow discharge increases, the ratio of lower width to depth decreases and the speed of bar migration increases. The BRI initially increases, but the amount of change decreased with time. In addition, when the steady flow discharge increases, the BRI increased. In the case of SF, the speed of bar migration decreased with the change of the flow discharge. In terms of the morphological response to the peak flood discharge, the time lag also indicated. In other words, in the SF, the change of channel bed indicates a phase lag with respect to the hydraulic condition. In the result of numerical simulation of CF, the speed of bar migration depending on the peak flood discharges decreased exponentially despite the repeated flood occurrences. In addition, as in the result of SF, the phase lag indicated, and the speed of bar migration decreased exponentially. The BRI increased with time changes, but the rate of increase in the BRI was modest despite the continuous peak flooding. Through this study, the morphological changes based on the hydrological characteristics of the river were analyzed numerically, and the methodology suggested that a quantitative prediction for the river bed change according to the flow characteristic can be applied to the field.