• 한국노년학
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• v.38 no.4
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• pp.871-889
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• 2018

This study aims to explore social participation needs among the elderly in Korea from the perspective of the elderly participant's. 40 Q-samples are drawn from the Q-population including attitudes and needs toward social participation in later life based on news articles, essays, research, documentary, and television shows. 35 subjects are analysed by the QUANL program and the types of social participation needs are divided into four patterns which accounted for 60.16% of the total variance. The elderly's portrayal of an ideal social participation is about making independent decisions and being able to actively participate in the activities they chose to do. However, their most undesirable scenario would be being confused and uncertain of what they should do the remainder of their lives. The needs of social participation among the elderly varies on four indicators such as ego, social capital, life satisfaction, life vitality and these four indicators have two sub-categories with a total of 8 types of classification. These 8 types differ by priorities, adaptation to life changes, motivation to social participation, and desired activity. Findings suggest that researchers and policy makers need to consider service user perspective on social participation in later life, not service provider perspective.

• Journal of Korean Public Health Nursing
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• v.35 no.1
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• pp.120-134
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• 2021

Purpose: The reproductive health of women in early adulthood can affect pregnancy, childbirth, and menopause in later life. Menstrual symptoms not only affect daily life, but are also a reflection of a woman's reproductive health. This study was conducted to explore the factors affecting menstrual symptoms among university students. Methods: The general characteristics, life style, menstrual characteristics, stress, and menstrual symptom of 177 female students were assessed through an online survey at one university. An independent sample t-test, one-way variance analysis, correlation analysis, and multiple regression analysis were performed using the SPSS 22.0 program. Results: The menstrual symptom score was 91.68±32.11 points, and the score of 'mood change' was the highest. Stress (��=.38, p<.001), amount of menstruation (��=.20, p=.001), menarche age (��=-.18, p=.003), health problems (��=.16, p=.010), and age (��=.15, p=.016) were found to have a significant effect on menstrual symptom, and the explanatory power of the regression model was 40%. Conclusion: This study investigated the degree and influencing factors of menstrual symptom using the Korean Menstrual Symptom Scale (KMSS) developed for Korean university students. Among the factors influencing menstrual symptom, stress appeared to play a significant role. Stress management, observation of menstrual characteristics, and general health care are necessary to maintain a woman's reproductive health.

• Proceedings of the Korean Society of Food Science and Nutrition Conference
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• 2004.11a
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• pp.185-197
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• 2004

Type 2 diabetes is characterized by hyperglycemia and hyperinsulinemia, features of insulin resistance. In vivo treatment of ob/ob mice with hydrolyzed fibroin reverses these pathological attributes (6). To explore the mechanism underlying this effect, we have used the 3T3-Ll adipocytes as a cell type which would represent the periphery, in vivo. Exposure of 3T3-Ll adipocytes to chronic insulin leads to the a 50% loss of insulin-stimulated glucose uptake. Chronic exposure to fibroin blocked, in part, the response to chronic insulin but also increased the sensitivity of control cells to the acute action of insulin. The later effect was most robust at physiological concentrations of insulin. Fibroin did not prevent the insulin-induced down-regulation of the insulin receptor or the tyrosine kinase activity associated with the receptor. Further, fibroin had no affect on the loss in activity of the insulin-sensitive down-stream kinase, Akt. Interestingly, fibroin accelerated glucose metabolism and glycogen turnover independent of insulin action. In addition, fibroin up-regulated GLUT1 which increased its expression at the cell surface and caused the redistribution of GLUT4 to the plasma membrane. Together, these later effects would lead to an improvement in hyperglycemia in vivo which would in turn reduce the need for insulin.

• Journal of Korean Public Health Nursing
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• v.3 no.1
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• pp.5-17
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• 1989

The purpose of this study was to investigate the natural menopause age of middle-aged women in Korea and to analyse various factors affecting them. For the collection of date, 1,140 women aged between 45-54 were selected through stratified sampling technics in Seoul and at a rual area in Kyong KiProvince. They were interviewed from Nov. 1 through Dec. 31,1987 by use of questionnaires made after pilot study had been performed twice. Among them the final subjects for analysis were restricted to only those who had experienced menopause or irregular menstruation during the past one year, the number of which was total 410:206 in urban and 204 in rural area. For the analysis, menopause age was used as dependent variables while fertility variables, socio-economic variables, bio-physical varibles, and insight of life variables were classified as independent variables. Dependent variables such as menopause was tested and analysed by descriptive statistical methods(e.g., frequency, percentage, mean, $X^2-test.$ t-test, ANOVA). The relation between menopause age and independent variables was analysed by use of Pearson's correlation coefficients. For the analysis of various factors affecting menopause age, multiple stepwise regression method was used. The obtained results are summarized as follows: 1. The natural menopause age of Korean women were 47.2 mean age: it was 47.7 and 46.7 mean age in urban and rural area respectively, which revealed that the former was later then the latter by one year. And the recollective error on menopause starting age between the menopause group and the group who had experienced irregular menstruation during the past one year was 0.4-0.7 year. 2. The main factors affecting the menopause age were (1) the duration of marital life, (2) the duration of oral pill use, (3) insight of life and economic status, (4) educational background. (5) menarche, (6) usual menstruation amount, (7) electic charge. and (8) area. These factors. altogether, could explain $18.4\%$ of factors related with menopause, and they took the high percentage in the order mentioned.

• BMB Reports
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• v.49 no.7
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• pp.355-356
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• 2016

The THO/TREX complex consists of several conserved subunits and is required for mRNA export. In metazoans, THO/TREX binds a subset of mRNAs during RNA splicing, and facilitates their nuclear export. How THO/TREX selects RNA targets is, however, incompletely understood. In our recent study, we reported that THO is loaded onto Piwi-interacting RNA (piRNA) precursor transcripts independent of splicing, and facilitates convergent transcription in Drosophila ovary. The precursors are later processed into mature piRNAs, small noncoding RNAs that silence transposable elements (TEs). We observed that piRNAs originating from dual-strand clusters, where precursors are transcribed from both strands, were specifically affected by THO mutation. Analysis of THO-bound RNAs showed enrichment of dual-strand cluster transcripts. Interestingly, THO loading onto piRNA precursors was dependent on Cutoff (Cuff), which comprises the Rhino-Deadlock-Cutoff (RDC) complex that is recruited to dual-strand clusters by recognizing H3K9me3 and licenses convergent transcription from he cluster. We also found that THO mutation affected transcription from dual-strand clusters. Therefore, we concluded that THO/TREX is recruited to dual-strand piRNA clusters, independent of splicing events, via multi-protein interactions with chromatin structure. Then, it facilitates transcription likely by suppressing premature termination to ensure adequate expression of piRNA precursors.

• Pediatric Infection and Vaccine
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• v.26 no.3
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• pp.129-139
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• 2019

The human respiratory tract hosts both pathogenic and commensal bacteria. The development of well-conserved 16S rRNA sequencing and culture-independent techniques has enabled many achievements in the study of the human microbiome. Microbial composition of the respiratory tract in early childhood has been shown to correlate to respiratory health in later stages of life. This review highlights current understandings of respiratory microbiota development in healthy children, examples of microbial interactions, impacts on the host immune system, and the relationship between respiratory tract microbiome and respiratory health.

• BMB Reports
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• v.38 no.6
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• pp.650-660
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• 2005

Proteins accumulated in dry, stratified Arabidopsis seeds or young seedlings, totaled 1100 to 1300 depending on the time of sampling, were analyzed by using immobilized pH gradient 2-DE gel electrophoresis. The molecular identities of 437 polypeptides, encoded by 355 independent genes, were determined by MALDI-TOF or TOF-TOF mass spectrometry. In the sum, 293 were present at all stages and 95 were accumulated during the time of radicle protrusion while another 18 appeared in later stages. Further analysis showed that 226 of the identified polypeptides could be located in different metabolic pathways. Proteins involved in carbohydrate, energy and amino acid metabolism constituted to about 1/4, and those involved in metabolism of vitamins and cofactors constituted for about 3% of the total signal intensity in gels prepared from 72 h seedlings. Enzymes related to genetic information processing increased very quickly during early imbibition and reached highest level around 30 h of germination.

• Korean Journal of Oriental Medicine
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• v.1 no.1
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• pp.209-244
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• 1995

The time therapy in oriental medicine is to reserch physiological activity and pathological variation with time, or time with disease. In that, this therapy is to research the development of disease, progress, diagnosis, treatment, and the meaning of preventive medicine. The theory of time therapy has been developed form heaven-human corresponding principle, and fourtimes of seasons is related with human life. After that, this theory affects in yin-yang five circle principle and organ-meridian match system. The independent development was formed later, but the origin has progressed for a logn times. in relation with time therapy, traditional acupuncture therory suggested five semen. In twenty century, the doctor rheinhold voll suggested energy exchange theory, this theory is based on time therapy, but has partial differance also too. His oppinion is this´ the energy present in the body has a circulation following the acupuncture teaching, i.e., the organs and their meridians are flooded in a certain sequence by this flowing energy. This maximum times of the organs are of physiologic and pathologic significance to man. In next time, we will discuss the indivisual theory in detail, and wil have comparison, and considering too.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2007.05a
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• pp.131-136
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• 2007

According to the OECD Report, Korea passed the first threshold to an "aging society" in which the elderly aged over 65 make up at least 7 percent of the population in 2000, and in 2018, are due to pass the second to an "aged society" in which they make up at least 14 percent-just 18 years later. It took France (starting in 1864) 115 years to complete this transition. Even Japan, legendary for the rapidity of its aging, required 24 years. It means Korea has to prepare for the aging of its population within a very short time without mistakes. Meanwhile, in a 2005 survey of the elderly, 85.5% of them preferred aging in place to moving to elderly care facilities. That means housing planning for the elderly which provides them with independent living needs to be considered seriously. The digital technology integrated home may be one of the alternatives to support this idea. In order to find a way to user oriented digital homes for the elderly, this study identified the their needs on the physical features of the ideal home and the digital services necessary through digital life scenarios.

• Journal of the Korean housing association
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• v.9 no.3
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• pp.69-77
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• 1998

This study has been performed to analyze living arrangement in later life. In this study, 276 Koreans aged 60 or more were interviewed for their current household structure. The results are drawn as follows: 1. Of all the households with at least one person aged 60 or more, those living in three generations account for the largest proportion, 39.9 percent. For the regional difference, the rate was slightly higher in urban areas than in rural areas. 2. 48.7% of the subjects living in owned homes were households with elderly only, but only 23% of those living in rented homes are elderly only. Overall, the rate of elderly-only households becomes the highest for those living in owned single structure homes. This result indicates that the elderly with higher economic status are more likely to live without children than others. 3. As for birth order, those who grew up as the first child are most likely to live in elderly-only households, while others are in three generation homes. 4. The elderly with few children are more likely to live independently than those with many children, not because they are without dependable children, but because spend less resource for childbearing and therefore are more independent. 5. Overall in this, it is supported that socioeconomic status and independability are more influential factors on living arrangement of the elderly than regional or emotional factors.