• 제목/요약/키워드: Increased efficacy

검색결과 2,137건 처리시간 0.03초

Monosodium Iodoacetate 유발 골관절염 모델: 장기적인 약물효능 평가에 적합한가? (Osteoarthritis Model Induced by Monosodium Iodoacetate: Good Model for Long-term Drug Efficacy Test)

  • 서일복;박동수
    • 한방재활의학과학회지
    • /
    • 제25권4호
    • /
    • pp.21-28
    • /
    • 2015
  • Objectives This study was aimed to offer basic data in long term drug efficacy test using monosodium iodoacetate-induced osteoarthrits model. Methods Sixty male rats were divided into normal and osteoarthritic group. Rats of normal group were injected with 0.1 ml physiological saline, and rats of osteoarthritic group were inected with 0.1 ml monosodium iodoacetate (3 mg/ml) into each left and right knee joint cavities. Gross examination, proteoglycan contents and histopathological examination on the knee joint were performed at 10, 20, 40, and 60 days after injection. Results Grossly, degenerative changes at 10 days, desquamation at 40 days, and ulceration of articular cartilages at 60 days were observed. Proteoglycan contents in articular cartilages were decreased rapidly to 40 days, after than decreased gradually. Osteoarthritic scores were increased rapidly to 20 days, after than increased gradually to 60 days. Conclusions From above results, osteoarthritis model induced by a single intra-articular injection of monosodium iodoacetete is useful model for long term drug efficacy test.

낙상예방 운동 프로그램이 노인주간보호센터 재가노인의 하지 근력, 균형 능력 및 낙상효능감에 미치는 효과 (The Effects of Community-based Fall Prevention Exercise Program on Lower Extremity Muscle Strength, Balance Ability and Fall Efficacy in Older Adults)

  • 김은정;이한주;이선희
    • 근관절건강학회지
    • /
    • 제28권2호
    • /
    • pp.102-110
    • /
    • 2021
  • Purpose: This study aimed to verify the effects of a community-based fall prevention exercise program for older adults on lower extremity muscle strength, balance ability, and fall efficacy. Methods: This study recruited 30 participants, and the program was conducted for 10 weeks. The program included sessions on strength and balance exercises, conducted for 50 minutes a day and at least three times a week. The collected data were analyzed using non-parametric (Wilcoxon signed-rank test, generalized estimated equation) and parametric statistics (paired t-test, rmANOVA). Results: After 12 weeks of exercise program, lower extremity muscle strength and static-dynamic balance ability significantly increased. The fall efficacy increased from an average score of 2.48 points before the test to an average score of 2.91 points after the test. Regarding general characteristics, there were no significant differences in effect before and after the program, except for fall efficacy. Conclusion: The above results showed that the intervention of a community-based fall prevention exercise program for older adults was effective. Therefore, it is suggested that this exercise program be organized regularly within the center to provide periodic and long-term services.

초등학생 대상의 건강 효능감과 지식을 중심으로 한 심혈관 건강증진 중재 효과 (Intervention Effect on Health Efficacy and Knowledge in Cardiovascular Health Promotion Behaviors in Children)

  • Tak, Young-Ran;Yun, E-Hwa
    • 보건교육건강증진학회지
    • /
    • 제26권5호
    • /
    • pp.97-113
    • /
    • 2009
  • 목적: 본 연구는 학령기 아동 대상의 건강 효능감과 지식을 중심으로 한 심혈관 건강증진 중재 효과를 확인하기 위해 수행되었다. 방법: 본 연구는 반복측정 설계를 적용한 단일군 사전사후 연구 설계로 219명의 초등학생들 대상으로 하고 있다. 심혈관 건강증진 중재는 학교 수업을 기반으로 하는 주1회, 4주 교육으로 구성된 1차 중재와 부모에게 1차 중재 내용을 가정통신문의 형태로 전달하여 학생들의 건강 생활습관 유지에 있어서 부모의 역할을 강조하는 2차 중재로 구성되어 있다. 건강 효능감, 지식, 아동이 지각하는 부모의 모니터링에 대해 중재 전 기초 조사를 실시하고, 1차 중재 및 2차 중재 후 각각 실시하였다. 결과: 정신 건강 자아 효능감은 조사 시점에 따라 유의하게 증가하였다 (F = 32.88, p < 0.0001). 1차 및 2차 중재 후 신체 건강 자아 효능감의 경우 사전 조사에 비해 유의하게 증가하였으나 (F = 50.51, p < 0.0001), 부모 중재 기간 동안에는 건강 자아 효능감에 유의한 변화가 없었다. 지식수준은 전반적으로 증가하는 경향을 보였으나 (F =10.23, p < 0.0001), 부모 중재 후에는 오히려 감소하는 경향을 보였다. 또한 전반적인 자아 효능감에 영향을 미치는 요인으로 아동이 지각한 부모 모니터링인 것으로 나타났다. 결론: 본 연구의 결과는 학교 기반의 심혈관 건강 증진 프로그램이 건강 자아 효능감과 지식수준을 향상시키는 데 있어서 효과적이라는 기존 연구 결과를 지지하고 있다. 이 외에 학령기 아동의 건강 생활 습관 유도를 목적으로 건강 자아 효능감과 지식수준 향상을 위한 중재를 수행하는 데 있어서 부모의 영향을 고려해야 함을 제시하고 있다.

중년여성의 부부조화도와 자기효능감이 건강증진행위에 미치는 영향 (Effects of Husband and Wife Compatibility and Self-Efficacy on Health Promotion Behavior in Middle Aged Women)

  • 최정
    • 기본간호학회지
    • /
    • 제14권4호
    • /
    • pp.507-514
    • /
    • 2007
  • Purpose: The purpose of this study was to identify the effects of husband and wife compatibility and self efficacy on health promotion behavior and define the main factors influencing health promotion behavior in middle aged women. Method: Using a structured questionnaire, data were collected from 311 middle aged women. Descriptive statistics, Pearson correlation coefficient, Stepwise multiple regression with SAS package were used for data analysis. Results: The mean score of husband and wife compatibility was 3.55(${\pm}.56$), self efficacy was 3.51(${\pm}.54$), and total health promotion behavior was 2.91(${\pm}.37$), with scores for subcategories as follows: interpersonal support 2.86(${\pm}.59$), self-actualization 2.74(${\pm}.56$), nutrition 2.56(${\pm}.63$), health responsibility 2.32(${\pm}.60$), stress management 2.28(${\pm}.51$), and exercise 1.87(${\pm}.74$). Husband and wife compatibility, and self efficacy were positively related to health promotion behavior and all subcategories of health promotion behavior. Also husband and wife compatibility were positively related to self efficacy. The major factors that affect health. promotion behavior in middle aged women were husband and wife compatibility, self efficacy, economic level, and religion, which explained 32.6% of health promotion behavior. Conclusion: The results indicate that health promotion behavior may be increased through interventions directed at improving the husband and wife compatibility.

  • PDF

전기 자극이 여성 노인의 만성 무릎통증, 운동자기효능 및 삶의 질에 미치는 효과 (Effects of Electrical Stimulation Therapy on Chronic Knee Pain, Exercise Self-Efficacy, and Quality of Life in Korean Elderly Women)

  • 석소현
    • 성인간호학회지
    • /
    • 제19권3호
    • /
    • pp.508-516
    • /
    • 2007
  • Purpose: This study was to examine the effects of electric stimulation therapy on chronic knee pain, exercise self-efficacy, and quality of life in Korean elderly women. Methods: The design was an unequivalent control pretest-posttest study. Samples were total of 60 (experimental: 30, control: 30) elderly women with healthy cognitive and communication abilities aged 65 years old and above. The experimental treatment involved was the electric stimulation of both thigh quadriceps muscles for 15 minutes per treatment, 3times per a week, for a total of 12 weeks. Measurements taken were S-F MPQ and AIMS for chronic knee pain, exercise self-efficacy measurement for exercise self-efficacy, and S-F 36 scale for quality of life. Data were analyzed using SPSS PC+ 12. Results: Chronic knee pain according to the Short-Form McGill Pain Questionnaire (t=43.563, p=.000) and Arthritis Impact Measurement Scale (t=31.364, p=.000) were significantly decreased in the experimental group by the application of electrical stimulation therapy. Exercise self-efficacy (t=107.116, p=.000) and quality of life (t=76.429, p=.000) were significantly increased in the experimental group by the application of electrical stimulation therapy. Conclusion: Electrical stimulation therapy could be a more effective primary nursing intervention in decreasing chronic knee pain, and on increasing exercise self-efficacy and quality of life for Korean elderly women.

  • PDF

임상실습 오리엔테이션 프로그램이 간호학생의 첫 임상실습에 대한 불안, 자아존중감 및 자기효능감에 미치는 효과 (Effect of Clinical Practice Orientation Program on Anxiety, Self-Esteem and Self-Efficacy in College Students in Nursing)

  • 이숙희
    • 기본간호학회지
    • /
    • 제15권4호
    • /
    • pp.539-547
    • /
    • 2008
  • Purpose: This study is done to identify how a clinical practice orientation program would affect anxiety, self-esteem and self-efficacy in college students in nursing. Method: Data was collected from 127 nursing students in February, 2008. The collected data were analyzed with the SPSS/Win 12.0 program, using t-test, ANOVA, paired t-test and Pearson's correlation coefficients. Results: The total mean scores were; anxiety 53.22/80, self-esteem 29.51/40 and self-efficacy in 59.76/85. Self-esteem and self-efficacy level were significantly different according to the level of Fundamentals practice and satisfaction with nursing as a major satisfaction(p=.001). The effect of the orientation program on clinical practice were a significantly increased in self-esteem and self-efficacy (p=.000). But in terms of anxiety, the effect was the opposite. So study to identify other factors causing anxiety and strategies to reduce the anxiety need to be considered. Conclusion: It is important to improve self-esteem and self-efficacy and the study results indicate that an orientation program is one strategy that needs to be developed to meet these needs for college students in nursing.

  • PDF

동아리활동 비만관리 프로그램이 비만아동의 신체조성, 자기효능, 건강증진행위에 미치는 효과 (Effects of Club Obesity Management Program for Obese Children on Body Composition, Self Efficacy, and Health Promotion)

  • 남성미
    • 한국보건간호학회지
    • /
    • 제27권3호
    • /
    • pp.619-632
    • /
    • 2013
  • Purpose: The purpose of this study was to develop an obesity management program for obese children and examine its effects on body composition, self-efficacy, and health promotion. The obesity management program was based on a KAP & HBM mixed model and consisted of health education and group playing exercises. Method: This study was implemented at one elementary school in K city for a total of 12 weeks. The study subjects were a single group, and their body composition, self-efficacy, and health promotion were assessed at both pre-treatment and post-treatment. Data were analyzed by Wilcoxon Signed Rank Test using SPSS WIN 20.0. Result: After the program, the average height of subjects increased by 0.9cm (p=.001), whereas BMI decreased by $0.64kg/m^2$ (p=.003), obesity index decreased by 3.79% (p=.003), and body fat decreased by 1.34% (p=.002). There were significant effects on diet self-efficacy (p=.027), exercise self-efficacy (p<.001), and health promotion (p=.001). Conclusion: This obesity management program reduced the degree of obesity and improved self-efficacy and health promotion. Therefore, the obesity management program is an effective intervention method for elementary-aged obese children.

의복구매효능감이 소비자 만족 형성과정에 미치는 영향 (The Influence of Self-Efficacy in Purchasing Clothes on Consumer Satisfaction Formation Process)

  • 고선영
    • 한국의류학회지
    • /
    • 제35권3호
    • /
    • pp.281-291
    • /
    • 2011
  • This study investigates the influence of self-efficacy in purchasing clothes in the consumer satisfaction formation process. A survey was conducted on 300 adults living in the Seoul and Gyeonggi area and 231 completed questionnaires were used for analysis. The survey questionnaires measured the respondent's self-efficacy in purchasing clothes, expectation, perceived performance, expectation confirmation, and satisfaction level. The data were analyzed by moderated regression analysis. The results are as follows. First, for apparel products, perceived performance, and expectation confirmation have a direct effect on consumer satisfaction, while expectation has no direct effect on consumer satisfaction. This finding agrees with the results reported in a previous study on consumer goods with low ambiguity in assessing products and services including sneakers, underwear, cereals, and financial services. Second, the lower the self-efficacy in purchasing clothes, then the increased effect of the expectation confirmation that influences consumer satisfaction. However, the self-efficacy in purchasing clothes did not show any moderating effect on the perceived performance affecting the consumer satisfaction. The self-efficacy in purchasing clothes seems to have a moderating effect on the consumer satisfaction formation process by affecting the ambiguity in pre-purchase product assessment and not in post-purchase product evaluation.

심폐소생술 교육 후 재교육이 간호대학생의 지식, 수행능력 및 자기효능감 지속에 미치는 효과 (Effects of cardiopulmonary resuscitation reeducation on persistence of knowledge, performance and self-efficacy of nursing students)

  • 채명정;이진희;송인자;김진일
    • 한국응급구조학회지
    • /
    • 제19권1호
    • /
    • pp.51-62
    • /
    • 2015
  • Purpose: This study was undertaken to examine the effects regarding reeducation of cardiopulmonary resuscitation on persistence of nursing students' knowledge, performance, and self-efficacy. Methods: The research design for this study was a repeated experimental design featuring 35 female nursing students. Participants were educated using the standardized cardiopulmonary resuscitation protocol from the American Heart Association. Three months after the initial education, participants received reeducation about cardiopulmonary resuscitation. Knowledge and self-efficacy were measured before the initial education. Knowledge, performance, and self-efficacy were measured immediately after the initial education, 3 months later, and 6 months later. Collected data were analyzed using PASW Statistics 18.0. Results: Knowledge and self-efficacy significantly increased immediately after the initial education; knowledge, performance, and self-efficacy significantly decreased 3 months afterwards. No further decrease occurred until 3 months after reeducation. Conclusion: These results suggest that the duration between initial education and reeducation was insufficient, although the effects of cardiopulmonary resuscitation education were maintained 3 months after reeducation.

상과염 환자에서 자기효능증진 프로그램의 효과 (Effects of Self-efficacy Promotion Program for Patients with Epicondylitis)

  • 김선화;김복자
    • 임상간호연구
    • /
    • 제16권2호
    • /
    • pp.43-55
    • /
    • 2010
  • Purpose: This study was done to evaluate the effects of program promoting self-efficacy patients with epicondylitis. Methods: Forty-three patients with unilateral epicondylitis were enrolled in this study between January, 2 and April, 28, 2009. The patients were assigned to one of two groups: Nineteen patients in the intervention group were given the self-efficacy promotion program with specific home instruction and the 24 in the control group were treated with conventional treatment. Pain by numeric rating scale, anxiety, and the self-efficacy of exercise were evaluated before the program, and 4 weeks after completing the intervention. The number of exercises was checked after the intervention. The data were analyzed using descriptive statistics, t-test, Chi-square test, paired t-test, Pearson's correlation coefficients with SPSS 14.0 program. Results: Anxiety in the intervention group was significantly lower than the control group(p=.018). Maximal and resting pain in the control group were lower than the intervention group( p=.000, p=.003). The self-efficacy of exercise and the number of exercises increased in the intervention group but there was no significant difference (p=.057, p=.052). Conclusion: The results of this study indicate that a program promoting self-efficacy for patients with epicondylitis could be a useful nursing intervention to reduce anxiety.