• Title/Summary/Keyword: Inclusion removal

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Discovery Elbow System arthroplasty polyethylene bearing exchange: outcomes and experience

  • Daniel L J Morris;Katherine Walstow;Lisa Pitt;Marie Morgan;Amol A Tambe;David I Clark;Timothy Cresswell;Marius P Espag
    • Clinics in Shoulder and Elbow
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    • v.27 no.1
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    • pp.18-25
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    • 2024
  • Background: The Discovery Elbow System (DES) utilizes a polyethylene bearing within the ulnar component. An exchange bearing requires preoperative freezing and implantation within 2 minutes of freezer removal to allow insertion. We report our outcomes and experience using this technique. Methods: This was an analysis of a two-surgeon consecutive series of DES bearing exchange. Inclusion criteria included patients in which exchange was attempted with a minimum 1-year follow-up. Clinical and radiographic review was performed 1, 2, 3, 5, 8 and 10 years postoperative. Outcome measures included range of movement, Oxford Elbow Score (OES), Mayo Elbow Performance Score (MEPS), complications and requirement for revision surgery. Results: Eleven DESs in 10 patients were included. Indications were bearing wear encountered during humeral component revision (n=5); bearing failure (n=4); and infection treated with debridement, antibiotics and implant retention (DAIR; n=2). Bearing exchange was conducted on the first attempt in 10 cases. One case required a second attempt. One patient developed infection postoperatively managed with two-stage revision. Mean follow-up of the bearing exchange DES was 3 years. No further surgery was required, with no infection recurrence in DAIR cases. Mean elbow flexion-extension and pronosupination arcs were 107°(±22°) and 140° (±26°). Mean OES was 36/48 (±12) and MEPS was 83/100 (±19). Conclusions: Our results support the use of DES bearing exchange in cases of bearing wear with well-fixed stems or acute infection. This series provides surgeons managing DES arthroplasty with management principles, successful and reproducible surgical techniques and expected clinical outcomes in performing DES polyethylene bearing exchange. Level of evidence: IV.

Nitrogen Removal Rate of A Subsurface Flow Treatment Wetland System Constructed on Floodplain During Its Initial Operating Stage (하천고수부지 수질정화 여과습지의 초기운영단계 질소제거)

  • Yang, Hong-Mo
    • Korean Journal of Environmental Agriculture
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    • v.22 no.4
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    • pp.278-283
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    • 2003
  • This study was carried out to examine the nitrogen removal rate of a subsurface-flow treatment wetland system which was constructed on floodplain of the Kwangju River from May to June 2001. Its dimensions were 29m in length, 9m in width and 0.65m in depth. A bottom layer of 45cm in depth was filled with crushed granite with about $15{\sim}30\;mm$ in diameter and a middle layer of 10cm in depth had pea pebbles with about 10 mm in diameter. An upper layer of 5 cm in depth contained course sand. Reeds (Phragmites australis) were transplanted on the surface of the system. They were dug out of natural wetlands and stems were cut at about 40 cm height from their bottom ends. Water of the Kwangju River flowed into it via a pipe by gravity flow and its effluent was funneled back into the river. The height of reed stems was 44.2 cm in July 2001 and 75.3cm in September 2001. The number of stems was increased from $80\;stems/m^2$ in July 2001 to $136\;stems/m^2$ in September 2001. Volume and water quality of inflow and outflow were analyzed from July 2001 through December 2001. Inflow and outflow averaged 40.0 and $39.2\;m^3/day$, respectively. Hydraulic detention time was about 1.5 days. Average nitrogen uptake by reeds was $69.31\;N\;mg/m^2/day$. Removal rate of $NO_3-N$, $NH_3-N$, T-N averaged 195.58, 53.65, and $628.44\;mg/m^2/day$, respectively. Changes of $NO_3-N$ and $NH_3-N$ abatement rates were closely related to those of wetland temperatures. The lower removal rate of nitrogen species compared with that of subsurface-flow wetlands operating in North America could be attributed to the initial stage of the system and inclusion of two cold months into the six-month monitoring period. Increase of standing density of reeds within a few years will develop both root zones suitable for the nitrification of ammonia and surface layer substrates beneficial to the denitrification of nitrates into nitrogen gases, which may lead to increment in the nitrogen retention rate.

Hedgehog Oral Viral Papilloma (고슴도치 구강유두종)

  • Elfadl, Ahmed K.;Lee, Eun-Joo;Kim, Hyeong-Mi;Kim, Yong Deuk;Chung, Myung-Jin;Park, Jin-Kyu;Kim, Tae-Hwan;Kim, Shin-Yoon;Ghim, Soong-Gu;Kim, Jun Young;Jeong, Kyu-Shik
    • Journal of Life Science
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    • v.27 no.5
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    • pp.575-578
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    • 2017
  • Here we describe the histological lesion of a viral fibro-papilloma in a hedgehog. After surgical removal from maxilla, the solitary swollen mass was round to oval, yellowish with rough surface and measuring $6{\times}3{\times}2mm$ approximately. The tumor mass was submitted to the laboratory of pathology, college of veterinary medicine, Kyungpook National University for pathological diagnosis. Pathological examination of the tumor was established, the tumor was described grossly and sample was trimmed, sectioned and routinely prepared for histopathological evaluation. The tumor mass was diagnosed as viral fibro-papilloma, as the histological picture showed characteristic features of warts caused by papillomaviruses. The tumor characterized by thickening of the stratum spinosum (acanthosis) and basale, koilocytosis, intra-nuclear inclusion bodies in keratinocytes and fibrosis of submucosa. Further, viral inclusion bodies were demonstrated by Machiavello stain giving red color to the nuclei. No lymphocytes that responsible for regression of the wart could be detected, suggesting the poor possibility of spontaneous regression of the tumor. Papillomatosis is a disease of young animals, but in our case the infected Hedgehog was 5 years old, that maybe due to an impaired immune system, which is also shown by absence of lymphocytes. To the best knowledge of the author, this case presents the first report of viral fibropapillomatosis in Hedgehog.

Classification of Transport Vehicle Noise Events in Magnetotelluric Time Series Data in an Urban area Using Random Forest Techniques (Random Forest 기법을 이용한 도심지 MT 시계열 자료의 차량 잡음 분류)

  • Kwon, Hyoung-Seok;Ryu, Kyeongho;Sim, Ickhyeon;Lee, Choon-Ki;Oh, Seokhoon
    • Geophysics and Geophysical Exploration
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    • v.23 no.4
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    • pp.230-242
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    • 2020
  • We performed a magnetotelluric (MT) survey to delineate the geological structures below the depth of 20 km in the Gyeongju area where an earthquake with a magnitude of 5.8 occurred in September 2016. The measured MT data were severely distorted by electrical noise caused by subways, power lines, factories, houses, and farmlands, and by vehicle noise from passing trains and large trucks. Using machine-learning methods, we classified the MT time series data obtained near the railway and highway into two groups according to the inclusion of traffic noise. We applied three schemes, stochastic gradient descent, support vector machine, and random forest, to the time series data for the highspeed train noise. We formulated three datasets, Hx, Hy, and Hx & Hy, for the time series data of the large truck noise and applied the random forest method to each dataset. To evaluate the effect of removing the traffic noise, we compared the time series data, amplitude spectra, and apparent resistivity curves before and after removing the traffic noise from the time series data. We also examined the frequency range affected by traffic noise and whether artifact noise occurred during the traffic noise removal process as a result of the residual difference.

Effect of Culture Conditions and Signal Peptide on Production of Human Recombinant N-Acetylgalactosamine-6-Sulfate Sulfatase in Escherichia coli BL21

  • Hernandez, Alejandra;Velasquez, Olga;Leonardi, Felice;Soto, Carlos;Rodriguez, Alexander;Lizaraso, Lina;Mosquera, Angela;Bohorquez, Jorge;Coronado, Alejandra;Espejo, Angela;Sierra, Rocio;Sanchez, Oscar F.;Almeciga-Diaz, Carlos J.;Barrera, Luis A.
    • Journal of Microbiology and Biotechnology
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    • v.23 no.5
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    • pp.689-698
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    • 2013
  • The production and characterization of an active recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) in Escherichia coli BL21(DE3) has been previously reported. In this study, the effect of the signal peptide (SP), inducer concentration, process scale, and operational mode (batch and semi-continuous) on GALNS production were evaluated. When native SP was presented, higher enzyme activity levels were observed in both soluble and inclusion bodies fractions, and its removal had a significant impact on enzyme activation. At shake scale, the optimal IPTG concentrations were 0.5 and 1.5 mM for the strains with and without SP, respectively, whereas at bench scale, the highest enzyme activities were observed with 1.5 mM IPTG for both strains. Noteworthy, enzyme activity in the culture media was only detected when SP was presented and the culture was carried out under semi-continuous mode. We showed for the first time that the mechanism that in prokaryotes recognizes the SP to mediate sulfatase activation can also recognize a eukaryotic SP, favoring the activation of the enzyme, and could also favor the secretion of the recombinant protein. These results offer significant information for scaling-up the production of human sulfatases in E. coli.

Effect of Gas Absorbents on Quality Attributes and Respiration Characteristics of Mature-Green Mume (Prunus mume Sieb. et Zucc) Fruits during Storage at Ambient Temperature (가스흡착제 처리가 상온 유통 청매실의 품질 및 호흡특성에 미치는 영향)

  • Cha, Hwan-Soo;Hong, Seok-In;Chung, Myong-Soo
    • Korean Journal of Food Science and Technology
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    • v.34 no.6
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    • pp.1036-1042
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    • 2002
  • During storage at $25^{\circ}C$, the effect of gas absorbents, such as carbon dioxide scavenger, ethylene absorber, and their combinations, on respiration characteristics and quality attributes of mature-green Mume fruits packaged in $30\;{\mu}m$ low density polyethylene (LDPE) film was examined. Changes in quality attributes of the fruits were observed in terms of weight loss, titratable acidity, pH, fish firmness, color, water-soluble solid, and chlorophyll contents. In the presence of ethylene absorber $(KMnO_4)$, the physiological injury was remarkably suppressed, and there was no significant injury in Mume fruits at $25^{\circ}C$ for 10 days. Yellowing and softening were also noticeably reduced by the combination of plastic film packaging and inclusion of ethylene absorber. The respiration rate was slower in fruits sealed with ethylene absorber than in those with absorbent-free packaging. Using ethylene absorber, levels of oxygen and carbon dioxide were maintained at 2-3 and 7-8%, respectively, during storage at $25^{\circ}C$ for 10 days. The addition of carbon dioxide scavenger $(Ca(OH)_2)$, negatively affected the quality attributes and respiration characteristics of the fruits. Overall results showed that ethylene removal by gas absorbent in the film packages significantly prolonged the shelf life of the fruits at ambient temperature.

Geochemical Studies of Hydrothermal Gold Deposits, Republic of Korea : Yangpyeong-Weonju Area (한반도 열수 금광상의 지화학적 연구 : 양평-원주지역 광화대)

  • So, Chil-Sup;Choi, Sang-Hoon;Lee, Kyeong-Yong;Shelton, Kevin L.
    • Economic and Environmental Geology
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    • v.22 no.1
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    • pp.1-16
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    • 1989
  • Electrum-galena-sphalerite mineralization of the Yangpyeong-Weonju Au-Ag area was deposited in three stages of quartz and calcite veins which fill fault breccia zones. Fluid inclusion and stable isotope data show that ore mineralization was deposited at temperatures between $260^{\circ}C$ and $180^{\circ}C$ from fluids with salinities between 8.9 and 2.9 equivalent weight percent NaCl. Evidence of boiling indicates pressures of <50 bars, corresponding to depths of 220 to 550 m, respectively, assuming lithostatic and hydrostatic loads. Au-Ag deposition was likely a result of bolling coupled with cooling. Within stages I and II there is an apparent increase in ${\delta}^{34}S$ values of $H_2S$ with paragenetic time ; early -1.4~2.7‰ to later 6.6-9.2‰. The progressively heavier $H_2S$ values can be generated through isotopic re-equilibration in the ore fluid following removal of $H_2S$ by boiling or precipitation of sulfides. Measured and calculated hydrogen and oxygen isotope values of ore-forming fluids suggest meteoric water dominance, approaching unexchanged meteoric water values. Comparison of these values with those of other Korean Au-Ag deposits reveals a relationship between depth and degree of water-rock interaction. All investigated Korean Jurassic and Cretaceous gold-silver-bearing deposits have fluids which are dominantly evolved, meteoric water, but on1y deeper systems (${\geq}1.25km$) are exclusively gold-rich.

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Study on the Manufacturing techniques & Conservation of Iron Pot from Cheonmachong Ancient Tomb (천마총 출토 철부(鐵釜)의 제작기법 및 보존처리)

  • Lee, Seung Ryul;Shin, Yong Bi;Jung, Won Seob
    • Journal of Conservation Science
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    • v.30 no.3
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    • pp.263-275
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    • 2014
  • It's shown how to proceed the study on Manufacturing techniques & Conservation to the Iron Pot from Cheonmachong Ancient Tomb(the 155th Tomb in Hwangnam-dong). In order to investigate manufacturing techniques of the Iron Pot, some parts of the relic were gathered. After mounting, polishing and etching on the relic, analyzing the metal microstructure was conducted. Also it's conducted a SEM-EDS analysis on the nonmetallic inclusion. White iron structure was observed in the metallurgical structure inspection, SEM-EDS analysis. It seems to be dried slowly at room temperature after casting, doesn't look as particular heat treatment to improve brittleness. It is estimated that it's as the handle seam side were verified about 3cm inch wide, 1.5 thick in center of body, so 2 separate half-completed products was cast with width-type mould. The manufacturing techniques Using white cast iron structure, width-type mould are observable to the Iron Pot excavated from Sikrichong Ancient Tomb & Hwangnamdaechong grand Ancient Tomb around those were constructed the same time. It's able to recognize that it's almost identical manufacturing techniques at that time. Conservation is generically following those are survey of pretreatment, foreign material removal, stabilization, restoration and color matching in the order. cleaning & drying were added to the process as occasion demands. The strengthening treatment were difficult with artifact's volume, low concentration Paraloid NAD-10 solution was spread two or three times with a brush, surface hardening also came up with 15wt% Paraloid NAD-10 solution after the conservation was complete. There were connection & restoration for the restoration to the damage after modeling forms that it's similar to damaged parts by using the Fiber Reinforced Plastic resins(POLYCOAT FH-245, mold laminated type). Throughout this research, capitalizing on accumulations of measurements about the production technique of Iron Pot in the time of the fifth and 6th centuries is no less important than the Iron artifact's conservation for a better study in the future.

A study on improving self-inference performance through iterative retraining of false positives of deep-learning object detection in tunnels (터널 내 딥러닝 객체인식 오탐지 데이터의 반복 재학습을 통한 자가 추론 성능 향상 방법에 관한 연구)

  • Kyu Beom Lee;Hyu-Soung Shin
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.26 no.2
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    • pp.129-152
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    • 2024
  • In the application of deep learning object detection via CCTV in tunnels, a large number of false positive detections occur due to the poor environmental conditions of tunnels, such as low illumination and severe perspective effect. This problem directly impacts the reliability of the tunnel CCTV-based accident detection system reliant on object detection performance. Hence, it is necessary to reduce the number of false positive detections while also enhancing the number of true positive detections. Based on a deep learning object detection model, this paper proposes a false positive data training method that not only reduces false positives but also improves true positive detection performance through retraining of false positive data. This paper's false positive data training method is based on the following steps: initial training of a training dataset - inference of a validation dataset - correction of false positive data and dataset composition - addition to the training dataset and retraining. In this paper, experiments were conducted to verify the performance of this method. First, the optimal hyperparameters of the deep learning object detection model to be applied in this experiment were determined through previous experiments. Then, in this experiment, training image format was determined, and experiments were conducted sequentially to check the long-term performance improvement through retraining of repeated false detection datasets. As a result, in the first experiment, it was found that the inclusion of the background in the inferred image was more advantageous for object detection performance than the removal of the background excluding the object. In the second experiment, it was found that retraining by accumulating false positives from each level of retraining was more advantageous than retraining independently for each level of retraining in terms of continuous improvement of object detection performance. After retraining the false positive data with the method determined in the two experiments, the car object class showed excellent inference performance with an AP value of 0.95 or higher after the first retraining, and by the fifth retraining, the inference performance was improved by about 1.06 times compared to the initial inference. And the person object class continued to improve its inference performance as retraining progressed, and by the 18th retraining, it showed that it could self-improve its inference performance by more than 2.3 times compared to the initial inference.