• Title/Summary/Keyword: InSAS

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Variation in Energy and Nutrient Composition of Oilseed Meals from Different Countries (수입 박류사료내 에너지 및 영양소 함량의 변이)

  • Son, Ah Reum
    • Korean Journal of Poultry Science
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    • v.47 no.2
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    • pp.107-114
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    • 2020
  • This study was conducted to investigate the variation in nutrient composition of oilseed meals and to develop prediction equations for amino acid concentrations. Energy and nutrient contents were determined in a total of 1,380 feed ingredient samples including copra byproducts, corn distillers, dried grains with solubles, palm kernel byproducts, and soybean meal. The ingredient samples were imported to the Republic of Korea between 2006 and 2015. Data were analyzed using the MIXED procedure of SAS. The regression procedure of SAS was used to generate the prediction equation for the lysine concentration using the crude protein (CP) concentration as an independent variable. The concentrations of moisture, gross energy, CP, ether extract, crude fiber, ash, calcium, phosphorus, lysine, methionine, cysteine, and threonine in tested oilseed meals differed (P<0.05) depending on producing countries. The prediction equations for amino acid concentrations (% as-is basis) in the oilseed meals are: lysine = -1.08 + 0.080 × CP (root mean square error = 0.244, R2 = 0.924, and P<0.001); threonine = -0.297 + 0.044 × CP (root mean square error = 0.099, R2 = 0.958, and P<0.001). In conclusion, energy and nutrient compositions vary in the oilseed meals depending on the producing countries. Moreover, the crude protein concentration can be used as a suitable independent variable for estimating lysine and threonine concentrations in the oilseed meals.

Analysis of Bioequivalence Study using a Log-transformed Model (로그변환 모델에 따른 생물학적 동등성 판정 연구)

  • 이영주;김윤균;이명걸;정석재;이민화;심창구
    • YAKHAK HOEJI
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    • v.44 no.4
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    • pp.308-314
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    • 2000
  • Logarithmic transformation of pharmacokinetic parameters is routinely used in bioequivalence studies based on pharmacokinetic and statistical grounds by the United States Food and Drug Administration (FDA), European Committee for Proprietary Medicinal Products (CPMP), and Japanese National Institute of Health and Science (NIHS). Although it has not yet been recommended by the Korea Food and Drug Administration (KFDA), its use is becoming increasingly necessary in order to harmonize with international standards. In the present study, statistical procedures for the analysis of a bioequivalence based on the log transformation and a related SAS procedure were demonstrated in order to aid the understanding and application. The AUC parameters used in this demonstration were taken from the previous bioequivalence study for two aceclofenac tablets, which were performed in a single-dose crossover design. Analysis of variance (ANOVA), statistical power to detect 20% difference between the tablets, minimum detectable difference and confidence intervals were all assessed following log-transformation of the data. Bioequivalence of two aceclofenac tablets was then estimated based on the guideline of FDA. Considering the international effort for harmaonization of guidelines for bioequivalence tests, this approach may require a further evaluation for a future adaptation in the Korea Guidelines of Bioequivalence Tests (KGBT).

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Effect of Temporary Employees and Health Characteristics Female Non-Regular Female Workers (비정규직 여성근로자의 고용특성 및 건강에 미치는 인자: 산재보험패널조사)

  • Choi, Kil-Yong;Yang, Kyung-Soo
    • The Korean Journal of Health Service Management
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    • v.10 no.3
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    • pp.235-244
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    • 2016
  • Objectives : Using several waves of the Panel Study of Worker's Compensation Insurance(PSWCI), this study analyzed the effect of female workers on the health and lifestyles of korean workers in the sample year of 2014 (The first survey was completed in August-October 2013;, the second survey was completed in August-October 2014.) Methods : The research subjects were 24,672 women among workers who responded to the 2014 PSWCI panel report. Statistical analyses were performed with SAS version 9.4 (SAS Institute Inc., Cary, NC, USA). Results : According to the results of the analysis, women showed differences in female temporary workers, working conditions, classification of occupation, working period, and health conditions based on work-time conditions. The results show that female workers with disabilities have a direct positive effect on life satisfaction as we anticipated in the hypothesis. Conclusions : Female workers should focus on factors identified in this study when developing employment interventions to improve a health promoting lifestyle for their work environment.

Intention of overseas employment in Korean dental hygienists (치과위생사의 해외취업의사에 영향을 미치는 요인)

  • Yoo, Ja-Hea;Kim, Young-Jin;Noh, Hie-Jin
    • Journal of Korean society of Dental Hygiene
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    • v.13 no.6
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    • pp.933-939
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    • 2013
  • Objectives : The purpose of this study is to examine the relationship between general characteristics and the intention of overseas employment and job satisfaction by Korean dental hygienists. Methods : We conducted a survey of 562 dental hygienists working in dental clinics nationwide. Collected data were analyzed by using the SAS(Version 9.2, SAS Institute, Cary, N.C.) package. $x^2$ test was used to determine the general characteristics of the subjects including job satisfaction level and intention to work abroad. Results : Old aged dental hygienists tended to work in the country rather than abroad(p<0.05). Higher job satisfaction was closely related to working hours, monthly income, social status, and stability of employment(p<0.05). Job satisfaction was concerned with intention to overseas employment. The main purpose of overseas employment included economic benefits(35.99%), self realization(26.75%), and improvement of working condition(21.66%) in the group of overseas employment(p<0.05). The obstacles to overseas employment were mastery of language proficiency(60.94%) and related information(21.89%) in those who want to work abroad. Conclusions : In order to increase the number of Korean dental hygienists for overseas employment, it is necessary to improve working competence and job satisfaction.

A Study on the Characteristics of Injured Workers Rate and Work Environment of Male Workers for over 40 years (산업재해 남성 근로자의 작업환경의 특성에 관한 연구: 산재보험패널조사)

  • Choi, Kil-Yong;Yang, Kyung-Soo
    • The Korean Journal of Health Service Management
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    • v.10 no.1
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    • pp.131-142
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    • 2016
  • Objectives : Using several waves of the Panel Study of Worker's Compensation Insurance(PSWCI), this study analyzed the effect of work hours on health and lifestyle of Korean workers in a sample from the 2013~2014 year (The first survey was completed in August-October 2013; the second survey was completed in August-October 2014). Methods : The research subjects were 1,312 men from among employees who responded to a 2013 PSWCI panel report. Statistical analyses were done with SAS version 9.3 (SAS Institute Inc., Cary, NC, USA). Results : According to the results of the analysis, the male subjects had differences in economic activity and health conditions based on the length of working hours. There was a significant relationship among working hours and life satisfaction, and the correlation coefficients were statistically significant. The results show that workplace conditions has a direct positive effect on life satisfaction as we anticipated in the hypothesis. Conclusions : Management should focus on the factors identified in this study when developing employment interventions programs to improve the the promotion of healthy lifestyles for adults over the age of 40.

Characteristics and Outcomes of Trauma Patients via Emergency Medical Services

  • Cho, Dae Hyun;Lee, Jae Gil
    • Journal of Trauma and Injury
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    • v.30 no.4
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    • pp.120-125
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    • 2017
  • Purpose: The aim of this study was to identify clinical outcome and characteristics of trauma patients via emergency medical services (EMS). Methods: Medical records of the trauma patients visiting the emergency department were retrospectively collected and analyzed from January 2015 to June 2016 in the single institution. Of 529 registered patients, 371 patients were transported by - were enrolled. The parameters including age, gender, injury mechanism, Glasgow coma scale on arrival, presence of shock (systemic blood pressure <90 mmHg) on arrival, time to arrival from accident to emergency room (ER), need for emergency procedures such as operation or angioembolization, need for intensive care unit (ICU) admission, injury severity score (ISS), the trauma and injury severity score, revised trauma score (RTS), length of stay, and mortality rate were collected. The SAS version 9.4 (SAS Institute, Cary, NC, USA) was used for the data analysis. Results: Arrival time from the field to the ER was significantly shorter in EMS group. However, overall outcomes including mortalities, length of stay in the ICU and hospital were same between both groups. Age, ISS, RTS, and injury mechanisms were significantly different in both groups. ISS, RTS, and age showed significant influence on mortality statistically (p<0.05). Conclusions: The time to arrival of EMS was fast but had no effect on length of hospital stay, mortality rate. Further research that incorporates pre-hospital factors influence clinical outcomes should be conducted to evaluate the effectiveness of such a system in trauma care of Korea.

Menadione (Vitamin K3) Induces Apoptosis of Human Oral Cancer Cells and Reduces their Metastatic Potential by Modulating the Expression of Epithelial to Mesenchymal Transition Markers and Inhibiting Migration

  • Suresh, Shruthy;Raghu, Dinesh;Karunagaran, Devarajan
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.5461-5465
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    • 2013
  • Oral cancer is one of the most commonly occurring cancers worldwide, decreasing the patient's survival rate due to tumor recurrence and metastasis. Menadione (Vitamin K3) is known to exhibit cytotoxicity in various cancer cells but the present study focused on its effects on viability, apoptosis, epithelial to mesenchymal transition (EMT), anchorage independent growth and migration of oral cancer cells. The results show that menadione is more cytotoxic to SAS (oral squamous carcinoma) cells but not to non-tumorigenic HEK293 and HaCaT cells. Menadione treatment increased the expression of pro-apoptotic proteins, Bax and p53, with a concurrent decrease in anti-apoptotic proteins, Bcl-2 and p65. Menadione induced the expression of E-cadherin but reduced the expression of EMT markers, vimentin and fibronectin. Menadione also inhibited anchorage independent growth and migration in SAS cells. These findings reveal and confirm that menadione is a potential candidate in oral cancer therapy as it exhibits cytotoxic, antineoplastic and antimigratory effects besides effectively blocking EMT in oral cancer cells.

Analysis of Handling Qualities for Smart Unmanned Aerial Vehicle in Helicopter Flight Mode (스마트 무인기의 회전익 모드 비행성 분석)

  • Lee, Jang-Ho;Kim, Eung-Tai
    • Journal of Advanced Navigation Technology
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    • v.9 no.2
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    • pp.185-192
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    • 2005
  • The aim of this paper is to analyze handling qualities of tiltrotor aircraft(TR-S4) in helicopter flight mode including hovering and forward flight. Analysis of handling qualities is composed of aircraft response to control inputs that effect on stability and controllability. In short term response analysis, bandwidth is the critical parameter for small amplitude motions since it relates to the ability of a pilot to crisply start and stop maneuver. The handling qualities of TR-S4 in helicopter mode are analyzed with a SAS and an attitude controller and are satisfied level 1 in almost criteria with simulation of TR-S4 6-DOF nonlinear model.

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Reasoning Non-Functional Requirements Trade-off in Self-Adaptive Systems Using Multi-Entity Bayesian Network Modeling

  • Saeed, Ahmed Abdo Ali;Lee, Seok-Won
    • Journal of the Korea Society of Computer and Information
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    • v.24 no.3
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    • pp.65-75
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    • 2019
  • Non-Functional Requirements (NFR) play a crucial role during the software development process. Currently, NFRs are considered more important than Functional Requirements and can determine the success of a software system. NFRs can be very complicated to understand due to their subjective manner and especially their conflicting nature. Self-adaptive systems (SAS) are operating in dynamically changing environment. Furthermore, the configuration of the SAS systems is dynamically changing according to the current systems context. This means that the configuration that manages the trade-off between NFRs in this context may not be suitable in another. This is because the NFRs satisfaction is based on a per-context basis. Therefore, one context configuration to satisfy one NFR may produce a conflict with another NFR. Furthermore, current approaches managing Non-Functional Requirements trade-off stops managing them during the system runtime which of concern. To solve this, we propose fragmentizing the NFRs and their alternative solutions in form of Multi-entity Bayesian network fragments. Consequently, when changes occur, our system creates a situation specific Bayesian network to measure the impact of the system's conditions and environmental changes on the NFRs satisfaction. Moreover, it dynamically decides which alternative solution is suitable for the current situation.

Synthesis of Aluminophosphate using Structure Directing Agent containing Piperidine Moiety: Effect of SDA on Crystal Structure (피페리딘 구조유도분자를 이용한 알루미노포스페이트 제올라이트 합성: 피페리딘 구조유도분자가 결정구조 형성에 미치는 영향)

  • Shin, Hye Sun;Jang, Ik Jun;Shin, Na Ra;Ju, Bit Na;Cho, Sung June
    • Korean Chemical Engineering Research
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    • v.49 no.5
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    • pp.657-663
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    • 2011
  • Structure directing agent(SDA) containing piperidine moiety such as piperidine(PI), 2-methylpiperidine (MPI), 2,6-dimethylpiperidine(DMPI) and 2,2,6,6,-tetramethylpiperidine(TMPI), respectively has been utilized to synthesize aluminophosphate zeolite using hydrothermal method. The gel composition was $1.0Al_2O_3:1.0P_2O_5:0.76SDA:45H_2O$ and the hydrothermal heating was performed in an oven at 443 K and for 7 days at static mode. The obtained zeolitic material contained a lamellar structure when PI was used as the SDA. With a progressive increase of the SDA size, various structures of aluminophosphate including AlPO-5 of AFI structure were obtained. The aluminophosphate of SAS structure was formed when the largest TMPI was utilized as the SDA, which was confirmed by the Rietveld refinement. The result of $^{27}Al$ and $^{31}P$ MAS NMR of the sample suggested that Al and P were incorporated into the framework of the aluminophosphate.