• Title/Summary/Keyword: In-source fragmentation

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Identication of L328-IRS as a Proto-Brown Dwarf

  • Lee, Chang Won;Kim, Mi-Ryang;Kim, Gwanjeong;Siato, Masao;Myers, Philip C.;Kurono, Yasutaka
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.2
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    • pp.65.1-65.1
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    • 2013
  • Our understanding of how brown dwarfs form is limited by observational evidence. We report identification of a L328-IRS as a proto-brown dwarf embedded in an isolated dense molecular core. This source exhibits typical properties of a protostar, however, its luminosity (~0.05 $L{\odot}$) is far below than expected from the least massive protostar by the standard star formation theory. The most likely mass accretion rate (~2.4 10-7 $M{\odot}$ yr-1) inferred from its small bipolar outflow is an order of magnitude less than the canonical value for a protostar. The mass available in its envelope is less than 0.1 $M{\odot}$. These points suggest that L328-IRS will accrete the mass of a brown dwarf, but not that of a star. L328 is found to be fairly well isolated from other nearby clouds and seems to be forming three sub-cores simultaneously through a gravitational fragmentation process. Altogether with these, our direct detection of inward motions in L328 which harbors this proto-brown dwarf clearly supports the idea that a brown dwarf forms like a normal star.

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Production, Structural Elucidation, and In Vitro Antitumor Activity of Trehalose Lipid Biosurfactant from Nocardia farcinica Strain

  • Christova, Nelly;Lang, Siegmund;Wray, Victor;Kaloyanov, Kaloyan;Konstantinov, Spiro;Stoineva, Ivanka
    • Journal of Microbiology and Biotechnology
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    • v.25 no.4
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    • pp.439-447
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    • 2015
  • The objective of this study was to isolate and identify the chemical structure of a biosurfactant produced by Nocardia farcinica strain BN26 isolated from soil, and evaluate its in vitro antitumor activity on a panel of human cancer cell lines. Strain BN26 was found to produce glycolipid biosurfactant on n-hexadecane as the sole carbon source. The biosurfactant was purified using medium-pressure liquid chromatography and characterized as trehalose lipid tetraester (THL) by nuclear magnetic resonance spectroscopy and mass spectrometry. Subsequently, the cytotoxic effects of THL on cancer cell lines BV-173, KE-37 (SKW-3), HL-60, HL-60/DOX, and JMSU-1 were evaluated by MTT assay. It was shown that THL exerted concentration-dependent antiproliferative activity against the human tumor cell lines and mediated cell death by the induction of partial oligonucleosomal DNA fragmentation. These findings suggest that THL could be of potential to apply in biomedicine as a therapeutic agent.

Numerical Analysis of Electromagnetic and Temperature Fields Induced by Femtosecond Laser Irradiation of Silver Nanowires (은 나노선 펨토초 레이저 조사에 의해 유도되는 전자기장 및 온도장 수치 해석)

  • Ha, Jeonghong;Kim, Dongsik
    • Laser Solutions
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    • v.18 no.1
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    • pp.12-17
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    • 2015
  • This work performed numerical analysis of electromagnetic field and thermal phenomena occurring in femtosecond laser irradiation of silver nanowires. The local electric field enhancement was computed to calculate the optical energy dissipation as a Joule heating source and the thermal transport was analysed based on the two-temperature model (TTM). Electron temperature increased up to 1000K after 50fs and its spatial distribution became homogeneous after 80fs at the fluence of 100mJ/cm2. The result of this work is expected to contribute to revealing the photothermal effects on silver nanowires induced by femtosecond laser irradiation. Although the highest increase of lattice temperature was substantially below the melting point of silver, the experimental results showed resolidification and fragmentation of the silver nanowire into nanoparticles, which cannot be explained by the photothermal mechanism. Further studies are thus needed to clarify the physical mechanisms.

Study on the Residue Analysis of Organophosphorus and Organochlorine Pesticides with Ion Trap and Quadrupole Mass Spectrometer (Ion Trap Mass Spectrometer와 Quadrupole Mass Spectrometer를 이용한 유기인제 및 유기염소제 농약 분석에 관한 연구)

  • Rhee, Jae-Seong;Park, Hyun-Mee;Er, Yon-Woo
    • Journal of the Korean Chemical Society
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    • v.39 no.12
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    • pp.902-909
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    • 1995
  • Detection limit as well as calibration curves on organophosphorus pesticide(dimethoate, diazinon, parathion-methyl, fenitrothion, malathion) and BHCs were measured for evaluation of utility on qualitative or quantitative analysis of pesticides with ion Trap mass spectrometer and quadrupole mass spectrometer. As ionization source, EI and CI were adopted for qualitative analysis of pesticides by comparison of each fragmentation pattern. At the same time, the utility as trace analysis techniques through scan or selected ion monitoring(SIM) mode was evaluated. With ion trap for all pesticides, detection limit(DL, 1 ${\mu}L$ injection) on scan mode was ranged 0.008∼0.225 ng at signal to noise ratio 3. With quadrupole DL on scan mode was ranged 0.23∼3.1 ng over 0.032∼0.68 ng on SIM mode. The calibration curve with ion trap generated good linearity over 0.99 as correlation coefficient. As clean up procedure, Bio Beads S-X3 was used for the separation of oils from five organophosphorous pesticides in flour extractant showing more than 80% as recovery at most cases. In case of BHCs in jinseng with Florisil column, the recovery of pesticides has been 60% to 90%.

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Nondestructive Interfacial Evaluation and fiber fracture Source Location of Single-Fiber/Epoxy Composite using Micromechanical Technique and Acoustic Emission (음향방출과 미세역학적시험법을 이용한 단일섬유강화 에폭시 복합재료의 비파지적 섬유파단 위치표정 및 계면물성 평가)

  • Park, Joung-Man;Kong, Jin-Woo;Kim, Dae-Sik;Yoon, Dong-Jin
    • Journal of the Korean Society for Nondestructive Testing
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    • v.23 no.5
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    • pp.418-428
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    • 2003
  • Fiber fracture is one of the dominant failure phenomena affecting the total mechanical Performance of the composites. Fiber fracture locations were measured through the conventional optical microscope and the nondestructive acoustic emission (AE) technique and then were compared together as a function of the epoxy matrix modulus and the fiber surface treatment by the electrodeposition method (ED). Interfacial shear strength (IFSS) was measured using tensile fragmentation test in combination of AE method. ED treatment of the fiber surface enlarged the number of fiber fracture locations in comparison to the untreated case. The number of fiber fracture events measured by the AE method was less than optically obtained one. However, fiber fracture locations determined by AE detection corresponded with those by optical observation with small errors. The source location of fiber breaks by AE analysis could be a nondestructive, valuable method to measure interfacial shear strength (IFSS) of matrix in non-, semi- and/or transparent polymer composites.

Aesthetic Images in Men s Bodies and Fashion(I) - Focused on Eroticism in Men s Fashion- (남성의 몸과 패션에 표현된 미적 이미지(I) -남성 패션에 표현된 에로티시즘을 중심으로-)

  • 이민선;김민자
    • Journal of the Korean Society of Costume
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    • v.51 no.1
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    • pp.163-174
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    • 2001
  • The purpose of this study is to review the features of eroticism expressed in men's fashion, to explain psychological and social contexts which engender eroticism and to analyze in what way eroticism is portrayed in men s fashion in this context. Eroticism as the metonymy of forbidden sexual desire, has been embodied mostly in visual forms such as picture and photo. From a psychoanalytic view, the context in which eroticism is formed can be explained by primary narcissism and fetishism. Primary narcissism is the feeling of satisfaction with the self in which the subject who is admiring and the object of admiration are one and the same. Accordingly, in order to give rise to eroticism, both subject and object have to exist. Fetishism, the metonymy of castrated penis, is also one of the factors to produce eroticism. Metaphorically seen as a woman who has a penis, a man who dresses in the same manner as a woman dresses can be a source of eroticism to gays. From a sociological view, the context in which eroticism is fostered depends on the dynamic relations among social powers. In these relations, who is a subject or who is an object has been continuously changing. In the Post-modern culture appearing in the late 20th century, power begins to take various forms, and gays and women who had never been subjects begin to make man an object of eroticism. The other point is that social morality, ignoring desire itself, objectifies sexual desire and seeks to remove It by exchanging it for objectified symbols. The design elements provoking eroticism in men s fashion are exposure and decoration. In particular, models in exposure and decorative fashion have been objectified through the methods of fragmentation rather than showing the whole figure or removing a person s individuality or will,.

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EFFECT OF TUMOR NECROSIS FACTOR-α ON THE BONE METABOLISM (Tumor Necrosis Factor-α가 골대사에 미치는 영향)

  • Kim, Sang-Sub;Lee, Su-Jong
    • Restorative Dentistry and Endodontics
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    • v.24 no.1
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    • pp.187-199
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    • 1999
  • Bone remodeling is characterized by the continuing processes of osteoblast-mediated bone formation and osteoclast-mediated bone resorption. Bone metabolism is tightly regulated at the local level by networks of hormones, cytokines, and other factors. In pathological conditions of bone remodeling, including osteoporosis and periodontal diseases, inflammatory cytokines and local mediators are responsible for enhancement of osteoclast resorption and inhibition of repair at the sites of bone resorption. TNF-${\alpha}$ is a pleiotropic hormone with actions on the differentiation, growth, and functional activities of normal and malignant cells from numerous tissues. TNF-${\alpha}$ has been proposed as a local mediator of the control of bone turnover in situations of chronic inflammation, and it has been assumed that the local source of TNF-${\alpha}$ is the monocyte in the adjacent bone marrow or the local circulation. TNF-${\alpha}$ is a potent inducer of bone resorption. TNF-${\alpha}$ is known to induce the activation of apoptotic signaling pathway, which leads to the apoptosis of bone cells. We demonstrated that treatment of murine osteoblastic MC3T3E1 cells with TNF-${\alpha}$ decreases proliferation as well as alkaline phosphatase (ALP) activity in a dose depenent manner. In addition, TNF-${\alpha}$ increases osteoclast-like cell formation in $1{\alpha}$, 25(OH)2D3 or PGE2-treated bone marrow cell culture. When cells were cultured in TNF-${\alpha}$ free ${\alpha}$-MEM, this inhibitory effect of ALP activity was reversible up to 10 ng/ml TNF-${\alpha}$, in contrast, at the 20 ng/ml TNF-${\alpha}$, irreversible. In this concentration, TNF-${\alpha}$ may induce apoptosis in MC3T3E1 cells. In this study, TNF-${\alpha}$ induces apoptosis resulting in chromosomal DNA fragmentation, preceded by JNK/SAPKs and caspase-3 activation. Our present results show that JNK/SAPKs and caspase-3 are activated by TNF-${\alpha}$, suggesting that the JNK/SAPKs and caspase-3 participate in the bone resorption, associated with apoptosis.

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A Study on Changes in Impervious Surface Area Rate at Administrative Units for Gyeongsangnam-do (경상남도 행정구역별 불투수면적률 현황 및 변화 연구)

  • Kim, Hyeonjoon;Choi Yoonhee;Kim, Hakkwan;Jang, Min-Won
    • Journal of Korean Society of Rural Planning
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    • v.29 no.4
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    • pp.117-125
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    • 2023
  • This study aimed to analyze the recent status and changes in impervious surface areas and their ratios across regions in Gyeongsangnam-do, providing fundamental data for regional development and impervious surface management. Based on the 'Guidelines for Calculating Water Cycle Management Indicators for Nonpoint Pollution Source Control(Ministry of Environment)', we processed the land characteristics survey map(shapefile) from 2018 and 2022 to analyze impervious surface area and their rates by administrative boundaries. The impervious surface area in Gyeongsangnam-do increased from 75,652 ha in 2018 to 81,055 ha in 2022, with the rate rising by 0.51% from 7.18% to 7.69%. The average of impervious surface area across 545 eupmyeon units expanded by approximately 9 ha, from 139.8 ha in 2018 to 148.8 ha in 2022, with the rate increasing by 0.71%. Concurrently, the whole population declined by 2.8% while the number of households surged by 6.4%, correlating with the growth in impervious areas. Despite population decreases, factors such as population migration, increased household fragmentation, new residential developments, and industrial facility expansions have consistently contributed to the rise in impervious surface area. Notably, even in areas with high impervious surface area rate, significant disparities existed between urbanized areas and predominantly rural regions. Furthermore, about 333 units(61% of the whole eupmyeons), showed negligible changes in their impervious surface area rate, with an increase of less than 0.5%.

Apoptosis and autophagy of muscle cell during pork postmortem aging

  • Chunmei Li;Xialian Yin;Panpan Xue;Feng Wang;Ruilong Song;Qi Song;Jiamin Su;Haifeng Zhang
    • Animal Bioscience
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    • v.37 no.2
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    • pp.284-294
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    • 2024
  • Objective: Pork is an important source of animal protein in many countries. Subtle physiochemical changes occur during pork postmortem aging. The changes of apoptosis and autophagy in pork at 6 h to 72 h after slaughter were studied to provide evidence for pork quality. Methods: In this article, morphological changes of postmortem pork was observed through Hematoxylin-eosin staining, apoptotic nuclei were observed by TdT-mediated dUTP nick end labeling assay, protein related to apoptosis and autophagy expressions were tested by western blot and LC3 level were expressed according to immunofluorescence assay. Results: In this study, we found the occurrence of apoptosis in postmortem pork, and the process was characterized by nucleus condensation and fragmentation, formation of apoptotic bodies, increase in apoptosis-related Bax/Bcl-2 levels, and activation of caspases. Autophagy reached its peak between 24 and 48 h after slaughter, accompanied by the formation of autophagosomes on the cell membrane and expression of autophagy-related proteins beclin-1, P62, LC3-I, LC3-II, and ATG5. Conclusion: Obvious apoptosis was observed at 12 h and autophagy reached its peak at 48 h. The present work provides the evidence for the occurrence of apoptosis and autophagy during postmortem aging of pork. In conclusion, the apoptosis and autophagy of muscle cells discovered in this study have important implications for pork in the meat industry.

Performance Analysis on Delay- and Disruption-Tolerant Network in Interplanetary Network (행성 간 통신에서의 지연/분열 허용 네트워크 성능 분석)

  • Baek, Jaeuk;Han, Sang Ik;Kim, In-kyu
    • Journal of Satellite, Information and Communications
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    • v.12 no.4
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    • pp.42-49
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    • 2017
  • Delay- and Disruption-Tolerant Network (DTN) has been considered as a key technology to overcome main challenges in interplanetary communications such as an intermittent connectivity and high bit error rates. The lack of end-to-end connectivity between source and destination results in long and variable delays and data loss, hence the Internet Protocols cannot operate properly in such environments because it requires an end-to-end connectivity. The DTN, which utilizes 'store-and-forward' message passing scheme between nodes, can overcome the lack of end-to-end connectivity in Interplanetary Network (IPN). In this paper, DTN is applied to 3-hop relay IPN, where messages are transmitted from Earth ground station to Lunar lander through Earth satellite and Lunar orbiter. ONE simulator is used to reflect the real environment of IPN and an efficient resource management method are analyzed to guarantee the message delivery by optimizing a message TTL (Time to Live), buffer size and message fragmentation.