• 한국지구과학회지
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• 제41권4호
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• pp.356-366
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• 2020

The accuracy of satellite-observed sea surface salinity (SSS) was evaluated in comparison with in-situ salinity measurements from ARGO floats and buoys in the seas around the Korean Peninsula, the northwest Pacific, and the global ocean. Differences in satellite SSS and in-situ measurements (SSS errors) indicated characteristic dependences on geolocation, sea surface temperature (SST), and other oceanic and atmospheric conditions. Overall, the root-mean-square (rms) errors of non-averaged SMOS SSSs ranged from approximately 0.8-1.08 psu for each in-situ salinity dataset consisting of ARGO measurements and non-ARGO data from CTD and buoy measurements in both local seas and the ocean. All SMOS SSSs exhibited characteristic negative bias errors at a range of -0.50- -0.10 psu in the global ocean and the northwest Pacific, respectively. Both rms and bias errors increased to 1.07 psu and -0.17 psu, respectively, in the East Sea. An analysis of the SSS errors indicated dependence on the latitude, SST, and wind speed. The differences of SMOS-derived SSSs from in-situ salinity data tended to be amplified at high latitudes (40-60°N) and high sea water salinity. Wind speeds contributed to the underestimation of SMOS salinity with negative bias compared with in-situ salinity measurements. Continuous and extensive validation of satellite-observed salinity in the local seas around Korea should be further investigated for proper use.

• 대한골관절종양학회지
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• 제3권1호
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• pp.9-17
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• 1997

Resistance to combination chemotherapy remains challenge in the treatment of osteosarcoma. One of the mechanisms of multiple drug resistance is an increased expression of the multidrug resistance gene(mdr1). Expression of the P-glycoprotein(mdr-1 gene product) was studied immunohistochemically and the mdr-1 gene by in situ hybridization in 33 osteosarcomas relating to various prognostic factors. Thirty cases out of 33 osteosarcomas(90.9%) showed positive cytoplasmic reactions with P-glycoprotein and nineteen instances(57.6%) were strong positive(2+). The older(>20 years) and female patients revealed more intense immunohistochemical reactions rather than those of the younger and male patients. Osteoblastic and chondroblastic osteosarcomas revealed more strong immunohistochemical reactions compared to fibroblastic types. There were no significant staining differences between the type of bony involvement, Broder's grade and the presence of necrosis. On follow-up, the mean survival rate was decreased in the strong positive group, however, this was not statistically significant. In situ hybridization for mdr-1 gene revealed positive signals in 22 cases out of 29 osteosarcomas(75.9%). Chemotherapy was done in 15 cases out of 28 patients(53.6%). The results of immunohistochemistry and in situ hybridization were not correlated with the protocols for chemotherapy. However, this result should be confirmed by a larger scale study about mdr1 mRNA expression.

• 한국동물학회지
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• 제37권3호
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• pp.304-310
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• 1994

Using in situ hybridization, we have mapped the anatomical localization of perikarya containing myNA that codes for sonadotropin releasing hormone (GnRH) in the brains of female frogs, R. dybowskii. DNA olisomers, with sequences complementary to the GnRH portion of pro-GnRH myNA sequence, were synthesized and hybridized to paraformaldehvde-fixed, sagittal sections of the whole brain stem. The distribution of the GnRH mRNA containing cell bodies was similar to that described for GnRH peptide by immunohistochemistrv. That is, cells containing GnRH mRNA were observed in the medial septal area, anterior preoptic area, ventromedial hvpothalamus and infundibular regions. However, another cell groups which contains GnRH mRNAs were also detected by in situ hybridization in the bed nucleus of hippocampal commissure, preoptic area, nucleus infundibularis dorsalis, mesencephalic nuclei and intermediolateral cell column of spinal cord areas. These results demonstrate the feasibility of using in situ hybridization as a strategy to study the distribution of GnRH neurons and the detection of GnRH gene expression in the vertebrates.

• Journal of Genetic Medicine
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• 제2권2호
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• pp.79-81
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• 1998

Genetic amniocenteses were performed in a series of 127 patients as a routine study. Samples from the patients were cultured by in situ method, flask method or both according to the state of amniotic fluid. The overall success rate of culture was 97.6% and no culture failure was observed in the flask method. It took 5 days first of all and 8.15 days average from set-up to harvest and there were 7.2 colonies per dish in in situ method. Therefore, it is suggested that in situ method which decreased the mean culture days and made clonal analyses possible, is a clinically available and even more reliable method in parallel with flask method in prenatal diagnosis.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2000년도 말뚝기초 학술발표회
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• pp.65-84
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• 2000

Europe and US which have more restrictive regulations than Korea about the noise and vibration during construction are using Auger-cast Pile to reduce the problem relating with noise and vibration. However Auger-cast Pile has problems like difficult quality control and low bearing capacity. In Europe, Displacement in-situ concrete Pile has been used to sove that problems since 1990s, and Korea has performed the test construction in 1997 and it has been used as the real structural foundation since 1998. Test and real construction results verified that the allowable capacity of the pile(diameter = 410mm) is between 70 and 100ton. Though De Beer & Van Imps design method utilizing CPT result is used to calculate the bearing capacity of the Displacement in-situ Pile, Korea is dependant upon the SPT as the sounding test, so design method utilizing SPT result is necessary to promote the application of the pile. To find out reasonable design method using SPT result, rearing capacity of the pile constructed in sand and clay in Korea was calculated using Meyerhof, SPT-CPT translation method, Nordlund, Douglas and DM-7 method, and the calculation results were compared to the load test result. Analysis result shows that SPT-CPT translation method is more reliable than others and economical design can be possible because it considers efficiently the friction capacity of Displacement in-situ Pile.

• 대기
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• 제14권2호
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• pp.7-10
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• 2004

A short review on TOTO (TOtable Tornado Observatory), one of the earliest in-situ observing systems for tornado, is provided. TOTO was outfitted with sensors for measuring wind, pressure and humidity, and storm researchers, in mid-1980's, tried to put it inside tornadoes for detailed studies on tornado, but failed. However, the accumulated knowledge and experience with TOTO lead to a successful field program in mid-1990's. A story about DOROTHY, a parody of TO TO in the movie "Twister!", is also provided.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1994년도 추계학술대회 논문집
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• pp.54-58
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• 1994

H$_2$ bake and GeH$_4$ clean are used as a in-situ pre-clean method in low temperature Si based epitaxial growth technology using rapid thermal processing chemical vapor deposition (RTPCVD). In this paper, the H$_2$ bake and GeH$_4$ clean processes are optimized for low surface defect density using Taguchi method. In H$_2$ bake process, the epitaxial growth temperature affects dominantly on the surface defect density, and the next affecting factors are H$_2$ bake temperature and rinse time in de-ionised water. In GeH$_4$ clean process, GeH$_4$ clean temperature affects most strongly on the surface defect density, and the minor factor is GeH$_4$flow rate. The optimum process conditions predicted fly Taguchi method agree well with tile experimental data in both in-situ clean processes.

• Nuclear Engineering and Technology
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• 제51권3호
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• pp.867-876
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• 2019

Second harmonic generation using nonlinear ultrasonic waves have been shown to be an early indicator of possible fatigue damage in nuclear power plant components. This technique relies on measuring amplitudes, making it highly susceptible to variations in transducer coupling and instrumentation. This paper proposes an experimental procedure for in-situ surface wave nonlinear ultrasound measurements on specimen with permanently mounted transducers under high cycle fatigue loading without interrupting the experiment. It allows continuous monitoring and minimizes variation due to transducer coupling. Moreover, relations describing the effects of the measurement system nonlinearity including the effects of the material transfer function on the measured nonlinearity parameter are derived. An in-situ high cycle fatigue test was conducted using two 304 stainless steel specimens with two different excitation frequencies. A comprehensive analysis of the nonlinear sources, which result in variations in the measured nonlinearity parameters, was performed and the effects of the system nonlinearities are explained and identified. In both specimens, monotonic trend was observed in nonlinear parameter when the value of fundamental amplitude was not changing.

• 한국산학기술학회논문지
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• 제7권4호
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• pp.697-703
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• 2006

본 논문에서는 국내. 외에서 처음으로 시도되는 현장타설 팽이기초공법의 거동특성을 검토하기 위하여 기초형식을 현장타설 팽이기초(In-Situ TBF), 공장제작 콘크리트 팽이기초(PC-TBF) 전면기초, 무처리 원지반으로 나누어 모형토조실험을 수행하였다. 모형실험결과 현장타설 팽이기초와 공장제작 콘크리트 팽이기초의 거동특성은 거의 유사하게 나타났으며, 이들 팽이기초는 원지반 및 전면기초에 비하여 지지력 증대효과가 있는 것으로 나타났다. 또한, 기초 형식에 따른 지중연직응력 분포를 검토한 결과 팽이기초 설치시 지중연직응력의 영향범위가 감소하는 것을 확인할 수 있었다. 한편, 지반이 조밀할수록 팽이기초의 응력분산효과가 감소하는 것을 알 수 있었으며, 향후 다양한 지반조건에서 모형실험과 수치해석을 통해 보다 많은 검토가 수행되어야 할 것으로 판단된다.

• 한국해양공학회지
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• 제24권1호
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• pp.99-105
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• 2010

The concentration and size analysis of in-situ suspended particulate material were measured using an optical instrument, LISST-100, in the bottom layer at the three inlets of the Seomjin River Estuary, mouth of Gwangyang bay, and Gwangyang bay-side of the Namhae Bridge. In the Seomjin river estuary and mouth of Gwangyang bay-side of the Namhae Bridge, the in-situ mean grain size of the suspended material changed from a uni-modal distribution with a dominant peak at a coarse fraction to a bi-modal distribution with a secondary peak at the finer particles. Seomjin River. The interactions between suspended particulate concentration and beam attenuation coefficient of suspended particulate matters depended on the supply of finer and coarser particles in the mouth of Gwangyang Bay and Seomjin River. So, interactions reflected difference of the concentration, mean size and sorting of suspended particulate matters. The difference of interaction showed dynamic behaviors to the resuspension and deflocculation processes increased river discharge. This showed that it may be possible to use the interactions between the suspended particle concentration and beam attenuation coefficient to monitor the temporal and spatial distributions of in-situ particles.