• Genomics & Informatics
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• 제20권3호
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• pp.34.1-34.11
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• 2022

Multilevel analysis is an appropriate and powerful tool for analyzing hierarchical structure data widely applied from public health to genomic data. In practice, however, we may lose the information on multiple nesting levels in the multilevel analysis since data may fail to capture all levels of hierarchy, or the top or intermediate levels of hierarchy are ignored in the analysis. In this study, we consider a multilevel linear mixed effect model (LMM) with single imputation that can involve all data hierarchy levels in the presence of missing top or intermediate-level clusters. We evaluate and compare the performance of a multilevel LMM with single imputation with other models ignoring the data hierarchy or missing intermediate-level clusters. To this end, we applied a multilevel LMM with single imputation and other models to hierarchically structured cohort data with some intermediate levels missing and to simulated data with various cluster sizes and missing rates of intermediate-level clusters. A thorough simulation study demonstrated that an LMM with single imputation estimates fixed coefficients and variance components of a multilevel model more accurately than other models ignoring data hierarchy or missing clusters in terms of mean squared error and coverage probability. In particular, when models ignoring data hierarchy or missing clusters were applied, the variance components of random effects were overestimated. We observed similar results from the analysis of hierarchically structured cohort data.

• 응용통계연구
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• 제23권3호
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• pp.521-531
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• 2010

구간중도절단은 중도절단의 가장 일반적인 개념으로 구간중도절단자료는 의학 및 역학분야의 연구에서 흔히 관찰된다. 본 연구에서는 구간중도절단의 상황에서 생존함수와 중간생존시간을 추정하는 방법으로 평균대치법과 자기일치법을 비교 연구하고, 실제 자료로 혈우병환자에서 선천성면역결핍바이러스 감염시점을 추정하였다. 또한 구간중도절단자료를 생성하는 새로운 방법을 제시하였으며, 생성된 구간중도절단자료를 이용한 모의실험을 통하여 두 추정치에 대한 다양한 비교연구를 시행하였다. 구간중도절단자료에서 생존함수와 중간생존시간을 추정할 경우 중도절단율이 크지 않다면 평균대치법이 자기일치법보다 더 우수한 추정치로 판명되었다.

• 한국통계학회:학술대회논문집
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• 한국통계학회 2004년도 학술발표논문집
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• pp.237-241
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• 2004

In standard time-to-event or survival analysis, the occurrence times of the event of interest are observed exactly or are right-censored. However in certain situations such as the AIDS data, the incubation period which is the time between HIV infection time and the diagnosis of AIDS is usually doubly censored. That is the HIV infection time Is interval censored and also the time of the diagnosis of AIDS is right censored. In this paper, we Impute the Interval censored infection time using the conditional mean imputation and estimate the coefficient factor of the regression analysis for the incubation period using Gibbs sampler. We applied parametric and semi-parametric methods for the analysis of the Incubation period and compared the results.

• 응용통계연구
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• 제23권5호
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• pp.955-966
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• 2010

정준상관 행렬도는 두 변수군 사이에 연관성이 있는 데이터 행렬을 시각적으로 묘사하고 데이터가 가진 패턴을 찾는데 유용하고, 분석의 더욱 정형화된 방법으로써 결과를 보여주기에도 유용하다. 그럼에도 불구하고, 자료에 결측값이 존재하는 경우에 대부분의 행렬도는 바르게 적용되지 않는다. 이 문제를 해결하기 위해, 결측률에 따라 중앙값과 평균, EM알고리즘, MCMC대체법을 사용해서 결측 자료를 추정한다. 완전하지 않은 자료의 행렬도의 결측값을 추정하더라도, 대체법과 결측률에 따라 행렬도의 모양이 달라진다. 따라서 Shin 둥 (2008)에서 제안한 RMS(root mean square)와 원 행렬도와 추정된 행렬도간의 형상 변동을 측정하고 비교하기 위한 PS(Procrustes statistic)를 사용한다.

• 응용통계연구
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• 제29권3호
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• pp.549-557
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• 2016

장기간의 기후 자료가 누적되다 보면 자료의 수집과정에서 시스템적 오류나 측정 장비의 고장 등으로 인하여 연속적 결측이 종종 발생하게 된다. 연속적인 결측 형태를 갖는 경우 시계열 결측 자료를 대체하는 것에 어려움이 따른다. 이러한 경우 참조시계열을 이용하여 결측값을 대체할 수 있다. 참조시계열은 결측이 발생한 시계열과 관련성이 높은 주변지점의 시계열로 구성할 수 있다. 본 연구에서는 결측값을 대체시킬 수 있는 3가지 결측복원 기법-수정된 정규화비율 방법, 회귀 방법, IDW 방법-을 비교하는 시뮬레이션을 수행하였다. 우리나라 14개 지점의 기후관측소의 일평균기온값을 대상으로 비교한 결과 남쪽 해안가에 위치한 기후관측소의 자료에 대해서는 IDW 방법이 가장 정확한 것으로 나타났으며, 그 외 지역의 기후관측소 자료에 대해서는 회귀 방법이 가장 정확한 것으로 나타났다.

• 농업과학연구
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• 제49권3호
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• pp.431-440
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• 2022

Hanwoo cattle are a unique and historical breed in Korea that have been genetically improved and maintained by the national evaluation and selection system. The aim of this study was to provide information that can help improve the accuracy of the estimated breeding values in Hanwoo cattle by showing the difference between the imputation reference chip platforms of genomic data and the scaling factor of the genetic relationship matrix (GRM). In this study, nine sets of data were compared that consisted of 3 reference platforms each with 3 different scaling factors (-0.5, 0 and 0.5). The evaluation was performed using MTG2.0 with nine different GRMs for the same number of genotyped animals, pedigree, and phenotype data. A five multi-trait model was used for the evaluation in this study which is the same model used in the national evaluation system. Our results show that the Hanwoo custom v1 platform is the best option for all traits, providing a mean accuracy improvement by 0.1 - 0.3%. In the case of the scaling factor, regardless of the imputation chip platform, a setting of -1 resulted in a better accuracy increased by 0.5 to 1.6% compared to the other scaling factors. In conclusion, this study revealed that Hanwoo custom v1 used as the imputation reference chip platform and a scaling factor of -0.5 can improve the accuracy of the estimated breeding value in the Hanwoo population. This information could help to improve the current evaluation system.

• 응용통계연구
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• 제24권5호
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• pp.871-881
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• 2011

In this paper we propose a logistic regression method to estimate the survival function and the median survival time in interval-censored data. The proposed method is motivated by the data augmentation technique with no sacrifice in augmenting data. In addition, we develop a cross validation criterion to determine the size of data augmentation. We compare the proposed estimator with other existing methods such as the parametric method, the single point imputation method, and the nonparametric maximum likelihood estimator through extensive numerical studies to show that the proposed estimator performs better than others in the sense of the mean squared error. An illustrative example based on a real data set is given.

• Journal of the Korean Data and Information Science Society
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• 제17권3호
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• pp.871-888
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• 2006

Many studies have been done to develop procedures to deal with missing values. Most common method is to reassign the other values to the missing data. The purpose of our study is to suggest adjusted Cohen methods and to compare the efficiency of them with other methods through a simulation study. The adjusted Cohen methods use an auxiliary variable to arrange ranking of the variable with missing values. It leads to a reduced mean square error(MSE) compared with the Cohen method.

• Wind and Structures
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• 제36권4호
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• pp.237-247
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• 2023

The emergence of high-rise buildings has necessitated frequent structural health monitoring and maintenance for safety reasons. Wind causes damage and structural changes on tall structures; thus, safe structures should be designed. The pressure developed on tall buildings has been utilized in previous research studies to assess the impacts of wind on structures. The wind tunnel test is a primary research method commonly used to quantify the aerodynamic characteristics of high-rise buildings. Wind pressure is measured by placing pressure sensor taps at different locations on tall buildings, and the collected data are used for analysis. However, sensors may malfunction and produce erroneous data; these data losses make it difficult to analyze aerodynamic properties. Therefore, it is essential to generate missing data relative to the original data obtained from neighboring pressure sensor taps at various intervals. This study proposes a deep learning-based, deep convolutional generative adversarial network (DCGAN) to restore missing data associated with faulty pressure sensors installed on high-rise buildings. The performance of the proposed DCGAN is validated by using a standard imputation model known as the generative adversarial imputation network (GAIN). The average mean-square error (AMSE) and average R-squared (ARSE) are used as performance metrics. The calculated ARSE values by DCGAN on the building model's front, backside, left, and right sides are 0.970, 0.972, 0.984 and 0.978, respectively. The AMSE produced by DCGAN on four sides of the building model is 0.008, 0.010, 0.015 and 0.014. The average standard deviation of the actual measures of the pressure sensors on four sides of the model were 0.1738, 0.1758, 0.2234 and 0.2278. The average standard deviation of the pressure values generated by the proposed DCGAN imputation model was closer to that of the measured actual with values of 0.1736,0.1746,0.2191, and 0.2239 on four sides, respectively. In comparison, the standard deviation of the values predicted by GAIN are 0.1726,0.1735,0.2161, and 0.2209, which is far from actual values. The results demonstrate that DCGAN model fits better for data imputation than the GAIN model with improved accuracy and fewer error rates. Additionally, the DCGAN is utilized to estimate the wind pressure in regions of buildings where no pressure sensor taps are available; the model yielded greater prediction accuracy than GAIN.

• 응용통계연구
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• 제21권3호
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• pp.361-375
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• 2008

본 논문에서는 패널의 일부를 규칙적으로 교체하는 4-8-4 교체표본설계에서 발생할 수 있는 항목 무응답을 대체하는 방법에 대하여 연구하였다. 특히 소득이나 취업과 같이 민감한 질문에 대하여 발생할 수 있는 무응답에 대하여 무시할 수 없는 무응답(nonignorable nonresponse) 체계하에서 발생하는 무응답을 가정하였다. 무응답들의 대체방법으로 모형에 기반한 대체방법을 고려하였으며 베이지안 방법을 이용하여 사후확률밀도함수를 최대화하는 최대사후우도추정량(maximum posterior likelihood estimator)을 구하였다. 그리고 대체된 자료를 이용하여 면접시점이 달라질 때 발생하는 편향을 추정하였으며 추정된 편향을 제거한 후 연속적인 두 조사기간에서의 각 칸의 확률과 고정된 시점에서의 주변확률을 계산하였다. 모의실험을 통해 최종적으로 도출된 결과를 평균제곱오차와 편향의 관점에서 비교하였다.