• Journal of the Korea Convergence Society
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• v.10 no.6
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• pp.95-101
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• 2019

The purpose of this study was to determine whether PNF respiratory convergence exercise increases the pulmonary function of normal adults by $45^{\circ}$ leaning sitting position. Twenty normal adults in their 20s were randomly assigned to an experimental group (n=10) or control group (n=10). Over the course of four weeks, the experimental group participated in PNF respiration exercises by $45^{\circ}$ leaning position for 30 minutes three per week. And the control group participated in PNF respiration exercises by supine position for 30 minutes three times per week. Subjects were assessed pre-test and post-test by measurement of pulmonary function. Our findings show that the experimental group had significant improvements in expiratoy reserve volume and vital capacity, maximal voluntary volume. In this study, the experimental group showed greater improvement in pulmonary function than the control group, which indicates that the PNF respiratory exercise by $45^{\circ}$ leaning sitting position is effective at increasing the pulmonary function of normal adults.

• Tuberculosis and Respiratory Diseases
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• v.43 no.4
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• pp.491-499
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• 1996

Background : Pleural effusion is a common disease in clinical practice but its effect on pulmonary function and altered pulmonary mechanics after removal of effusion are not still largely understood. Previous studies have shown that there is little or a relatively small improvement in pulmonary function and arterial blood oxygenation after therapeutic thoracentesis. The present study was designed to assess the effect on pulmonary function of pleural effusion and to test whether there was a significant improvement in pulmonary function and arterial oxygenation after thoracentesis and to observe long tenn effect after thoracentesis. Method : We examined flow-volume curve, body box and arterial blood gas analysis according to severity of effusion, present symptom, and symptom duration. Then, we measured changes of pulmonary function after thoracentesis and observed longterm effect after thoracentesis. Result: 1) Pleural effusion cause restrictive pulmonary insufficiency. Not only functional impairment of small airway but also large airway is provoked. 2) MMFR, FEV1, Raw, POz are earlier improved than FVC and TLC after thoracentesis and patients without complication have mild restrictive pulmonary insufficiency after longterm observation. 3) FVC, FEV1, & TLC are similarly restricted as severity of pleural effusion and po, is relatively decreased. 4) Cases with symptom duration 1 week or less and cases with dyspnea have more severe pulmonary insufficiency than others. 5) The flow volume curves show a relatively greater improvement in flow rates at large lung volumes than small airway. 6) Significant relationship is shown between first thoracentesis amount and changes of FEV1, FVC, TLC. Conclusion: Pleural effusion cause restrictive pulmonary insufficiency and not only functional impairment of small airway impairment but also large airway is provoked. Then, Pulmonary function is progressively improved after thoracentesis and remained mild restrictive pulmonary insufficiency after recovery.

• Journal of Chest Surgery
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• v.17 no.2
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• pp.292-298
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• 1984

Myasthenia 8ravis is a disorder of neuromuscular function due to a reduction of available acetylcholine receptors at the neuromuscular junction. Typically, the muscle weakness is worse after effort and improved by rest. In 1939, Blalock and associated reported a case of patient with myasthenia gravis who was successfully treated by thymectomy. Since then, operation has become increasingly important in the management of this disease. From 1968 to 1983, 10 cases of myasthenia gravis were operated at the Department of Thoracic and Cardiovascular Surgery,College of Medicine, Seoul National University. 1.Among 10 cases, 4 were male and 6 were female. 2.Thymectomy was performed in 9 cases, and 1 case of malignant thymoma with deeply infiltration to adjacent structure was not resectable. 3.There was 1 operative mortality with respiratory failure. 4.During follow-up period, most of them showed symptomatic improvement, but complete remission was not noticed in any case.

• Journal of Korean Medical Ki-Gong Academy
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• v.14 no.1
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• pp.39-51
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• 2014

Objects : This study is a report on treatment effect of the case that treated by using of oriental medical treatment to Amyotrophic Lateral Sclerosis(ALS) patient. Methods : The patient diagnosed with ALS was treated by using of acupuncture, physical therapy, Su-gi therapy, thermotherapy and herbal medicine during 180 days. K-ALSFRS-R score was used as the tool of treatment effect. Results : Despite the K-ALSFRS-R score reduction, the oriental medical treatment maintain the respiratory function and a speech. Conclusions : The oriental medical treatment is effective on local symptoms of ALS, but there were no functional improvement of ALS in this case study. It is necessary to have more examination about ALS.

• Advances in Traditional Medicine
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• v.6 no.4
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• pp.330-335
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• 2006

The present investigation was carried out to determine the efficacy and safety of Abutilon indicum (A. indicum) (Eng: Country Mallow, Fam: Malvaceae) in patients of bronchial asthma. Dried aerial parts of A. indicum were finely powdered and given in the dose of 1 gm tid to 30 patients of either sex in the range of 15 - 80 years with mild to moderate bronchial asthma with or without any concurrent medication. The respiratory functions (FVC, $FEV_{1}$, $FEF_{25-75%}$and MVV) were assessed using a spirometer prior to and after 4 weeks of treatment. Efficacy of the drug in improving clinical symptoms and severity of asthmatic attacks was evaluated by interviewing the patient and by physical and hematological examination at the end of the treatment. 4 weeks treatment with the drug showed statistically significant improvement in various parameters of pulmonary functions in asthmatic subjects. Also significant improvement was observed in clinical symptoms and severity of asthmatic attacks. None of the patient showed any adverse effect with A. indicum. The results of the present study suggest the usefulness of A. indicum in patients with mild to moderate bronchial asthma.

• Journal of Ginseng Research
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• v.46 no.3
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• pp.321-330
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• 2022

Coronavirus has been spreading rapidly around the world since it broke out in China in 2019. Respiratory diseases caused by coronavirus infection cause various diseases ranging from asymptomatic subclinical infections to severe pneumonia and cardiovascular complications, leading to death. In this regard, natural products are being studied to prevent various diseases caused by COVID-19. In current review, we would like to present mechanisms related to the inhibition of heart disease in ginseng and ginsenoside against SARS-CoV-2. In many previous studies, ginseng and ginsenoside are known to have antioxidant, blood flow improvement, improvement of vascular and heart function, blood pressure control, suppression of myocardial infarction and heart failure, and antiarrhythmia. Therefore, ginseng and ginsenoside have a possibility to suppress cardiovascular complications caused by COVID-19. Many of research provide evidence for ginseng and ginsenoside as treatments for the risk of cardiovascular complications. However, in this review, more specific contents on the proposition of the efficacy of ginseng and ginsenoside for COVID-19 should be presented. Therefore, we hope that researches to reduce cardiovascular complications of ginseng and ginsenoside for COVID-19 should be presented to reduce mortality for COVID-19.

• Archives of Reconstructive Microsurgery
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• v.9 no.1
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• pp.68-74
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• 2000

The treatment of chronic chest wounds should be focused on eradicating the infection and obliterating the dead space thus providing improved pulmonary function. Chronic chest wounds, although the incidence has decreased over the years, is still associated with high morbidity and prolong hospitalization. In cases where the disease is advanced and conventional measures fail, aggressive approaches achieve adequate resolution or significant improvement. This paper reports four cases of chronic chest wound including bronchopleural fistula and osteomyelitis managed by debridement followed by muscle coverage using latissimus dorsi, rectus abdominis, and omental flap. The intrathoracic reconstruction entails thorough debridement of empyema cavities, bronchpleural fistulas and infection focus. The infection must be completely eradicated prior to or at the time of flap transposition. The flaps used for obliteration of dead spaces provided adequate bulk, abundant blood supply, and minimal donor morbidity. The results were satisfactory with improved respiratory function without complications.

• Korean Journal of Applied Biomechanics
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• v.23 no.3
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• pp.261-269
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• 2013

The purpose of this study was to investigate the degree of improvement of scoliosis, muscle function and VAS between the exercise group and the control group after conducting correct posture exercise program with 20 female students diagnosed with scoliosis through PAPS in M middle school for 12 weeks. The conclusion was as follows. Cobb's angle in exercise group was changed from $11.6^{\circ}{\ae}2.5^{\circ}\acute{y} $ to $7.3^{\circ}{\ae}2.0^{\circ}\acute{y} $ which was statistically significant difference (p<.001). However, the change in Cobb's angle was not significant in control group, hence there was no statistically significant difference. The limber back strength was changed from $45.9^{\circ}{\ae}8.7$ kg to $51.6^{\circ}{\ae}14.9$ kg and sit-up was changed from $13.7^{\circ}{\ae}5.1$ times to $12.9^{\circ}{\ae}5.3$ times in exercise group, but they were not statistically significant. Control group also showed no statistically significant change in back strength and sit-up. The degree of VAS was changed from $7.3^{\circ}{\ae}1.6$ to $3.3^{\circ}{\ae}2.4$ which was a statistically significant difference (p<.01) in exercise group. However, there was no statistically significant difference in control group. Consequently, correct posture exercise program was considered to be effective for the reduction of Cobb's angle and degree of VAS for middle school female students with scoliosis. Therefore the correct posture exercise program can be recommended for youth scoliosis to improve and prevent the body imbalance and ultimately for the health of the youths.

• Tuberculosis and Respiratory Diseases
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• v.49 no.1
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• pp.30-36
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• 2000

Background : The purpose of decortication is to eliminate the infection focus and to improve the decreased lung function due to chronic empyema. However, lung function is not improved in all cases. It would be clinically useful if we could predict prepoperatively whether lung function would improve after decortication. The purpose of this study is to find useful indices for predicting the possible improvement of lung function after decortication. Method : The medical records of 37 tuberculous empyema patients who underwent pleural decortication were analyzed retrospectively from 1990 to 1996. The measurements of preoperative and postoperative foræd vital capacity(FVC) were used for evaluating the effects of decortication. Results : The sex ratio was 29:8 (male to female), and the median age was 34 years. The time interval between the formation of empyema and operation was 1 month to 30 years. Postoperative pulmonary function test was performed 5.4$\pm$2.6 months later. FVC(forced vital capacity) was significantly increased from 2.77$\pm$0.67(L) to 2.95$\pm$0.81(L). Interestingly, postoperative pulmonary function was significantly improved in patients who were less than 40 years old, within 4 months after diagnosis of tuberculous empyema, in the group with FVC of less than 60% of the predicted value and in the absence of calcification. Conclusion : The improvement of lung function after decortication was expected in patients younger than 40 years old, within 4 months after diagnosis of tuberculous empyema, in the group having less than 60% of the predicted FVC, without calcification.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.5 no.1
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• pp.18-22
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• 2005

Pompe disease is a genetic disorder caused by a deficiency of acid ${\alpha}$-glucosidase (GAA). This enzyme defect results in lysosomal glycogen accumulation in multiple tissues and cell types, with cardiac, skeletal, and smooth muscle cells the most seriously affected. Infantile-onset Pompe disease is uniformly lethal. Affected infants present in the first few months of life with hypotonia, generalized muscle weakness, and a hypertrophic cardiomyopathy, followed by death from cardiorespiratory failure or respiratory infection, usually by 1 year of age. Late-onset forms is characterized by a lack of severe cardiac involvement and a less severe short-term prognosis. Enzyme replacement therapy for Pompe disease is intended to address directly the underlying metabolic defect via intravenous infusions of recombinant human GAA to provide the missing enzyme. We experienced one case of Pompe disease in 3-years old boy that has improved his exercise ability and cardiac function after GAA enzyme replacement therapy.