• The Korean Journal of Physiology and Pharmacology
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• v.22 no.1
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• pp.81-89
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• 2018

This study evaluated the anti-asthmatic activities of 2,6-di-tert-butyl-4-hydroxymethylphenol (DBHP) that is a potent phenolic antioxidant in edible vegetable oil. The effects of DBHP on bronchial asthma were evaluated by determining the specific airway resistance (sRaw) and tidal volume (TV) during the immediate asthmatic response (IAR) and the late-phase asthmatic response (LAR) in guinea pigs with aerosolized ovalbumin-induced asthma. Recruitment of leukocytes and the levels of biochemical inflammatory mediators were determined in the bronchoalveolar lavage fluids (BALFs), and histopathological surveys performed in lung tissues. DBHP significantly inhibited the increased sRaw and improved the decreased TV on IAR and LAR, and also inhibited recruitment of eosinophils and neutrophils into the lung, and release of biochemical inflammatory mediators such as histamine and phospholipase $A_2$ from these infiltrated leukocytes, and improved pathological changes. However, anti-asthmatic activities of DBHP at oral doses of 12.5 to 50 mg/kg was less than those of dexamethasone (5 mg/kg, p.o.) and cromoglycate (10 mg/kg, p.o.), but more potent or similar to that of salbutamol (5 mg/kg, p.o.). These results in the present study suggest that anti-asthmatic effects of DBHP in the guinea pigs model of OVA-induced asthmatic responses principally are mediated by inhibiting the recruitments of the leukocytes and the release of biochemical inflammatory mediators from these infiltrated leukocytes.

• The Transactions of the Korea Information Processing Society
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• v.4 no.6
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• pp.1531-1540
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• 1997

In this paper, we presents automatic Korean continuous speech recognizer which is improved by the speech rate estimation and the compensation methods. Automatic continuous speech recognition is significantly more difficult than isolated word recognition because of coarticulatory effects and variations in speech rate. In order to recognize continuous speech, modeling methods of coarticulatory effects and variations in speech rate are needed. In this paper, the speech rate is measured by change of format, and the compensation is peformed by extracting relatively many feature vectors in fast speech. Coarticulatory effects are modeled by defining 514 Korean diphone set, and ETRI's 445 word DB is used for training speech material. With combining above methods, we implement automatic Korean continuous speech recognizer, which shows improved recognition rate, based on DHMM(Discrete Hidden Markov Model).

• The korean journal of orthodontics
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• v.45 no.4
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• pp.209-214
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• 2015

Maxillary protraction is the conventional treatment for growing Class III patients with maxillary deficiency, but it has undesirable dental effects. The purpose of this report is to introduce an alternative modality of maxillary protraction in patients with dentoskeletal Class III malocclusion using a modified C-palatal plate connected with elastics to a face mask. This method improved skeletal measurements, corrected overjet, and slightly improved the profile. The patients may require definitive treatment in adolescence or adulthood. The modified C-palatal plate enables nonsurgical maxillary advancement with maximal skeletal effects and minimal dental side effects.

• Journal of the Korean Society for Heat Treatment
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• v.13 no.6
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• pp.405-411
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• 2000

The effects of added elements, such as Co or Nb, on wear properties of high speed steel by powder metaliurgy(PM-HSS) had been eluminated in auther's previous paper. In addition, it is generally known that the wear properties of materials have been influenced by heat-treating conditions as well. Therefore, a study has been done to clarify the effects of heat-treating conditions on wear properties of PM-HSS. The wear tests have been performed under the same conditions as the previous paper using heat-treated PM-HSS(5%Co-1%Nb) with different quenching and tempering temperatures. The result of this paper shows that wear resistance of PM-HSS is improved with relatively high quenching temperature. However, tempering temperature is not sensitive to the wear resistance in the range of high quenching temperature. It may be deduced by the fact that the shear strength of matrix by strengthening mechanisms due to not only the quenching aging but also dispersion-hardening is improved.

• Journal of the Korean Society for Precision Engineering
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• v.30 no.12
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• pp.1265-1271
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• 2013

In this work, modeling and analysis of thermal effects laser drilling under water for ceramics were presented. Laser is a unique tool for machining ceramics due to the characteristic of non-contact material removal. However, ablation by a laser often induces a thermal effect on the material and an increased heat-affected-zone or deposition of debris can be observed on the machined parts. The underwater surrounding improved a heat transfer rate to cooling down the machined part and could prevent any deposition of debris near the machined surfaces and edges. The heat modeling was applied to obtain the temperature distributions as well as temperature gradients between the material and surroundings. The cooling effect of the underwater laser drilling was improved and a more stable temperature distribution was calculated. The actual laser drilling results of ceramic laser drilling were presented to verify the effects of underwater laser drilling.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.40 no.2
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• pp.57-64
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• 2008

In general, the entire of paper mulberry bark, which is not cut into pieces with an appropriate length, have been used in the pulping. This kind of pulping method couldn't accomplish the improvement of beating and sheet forming efficiency. For this reason, we investigated the effects of the cutting length of paper mulberry bast fiber on pulping and Hanji (Korean traditional paper) properties, in order to develop high quality Hanji manufacturing process. The cutting length variation of paper mulberry white bast did not great effects on pulp yields. The pulp yields based on pulping methods were sulfomethylated pulping av. 57.4%, alkali-hydrogen peroxide pulping av. 55.4%, and alkaline pulping av. 53.5% respectively. The optical properties such as brightness, opacity, scattering coefficient, and absorption coefficient were slightly improved by the increase of paper mulberry white bast cutting length. The increase of paper mulberry white bast cutting length resulted in poor sheet formation. Physical properties such as breaking length, TEA, tear index, burst index, and folding endurance were slightly improved by the increase of cutting length. The modified pulping processes, which used sulfomethylated method and alkali-hydrogen peroxide method, showed better pulp and sheet properties than conventional alkaline pulping.

• The Korean Journal of Food And Nutrition
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• v.26 no.3
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• pp.526-534
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• 2013

This study was conducted to examine the effects of Opuntia ficus-indica complex (OF) on the lipid metabolism, bile acid in feces, alanine aminotransferase (ALT) activity, aspatate aminotransferase (AST) activity, composition of urine and expression of cholesterol related mRNA in streptozotocin (STZ)-induced diabetic rats. Thirty two male Sprague-Dawley rats were randomly divided into non-diabetic control (NC), diabetic control (DC), diabetic OF of 2% (OF-2) and diabetic OF of 5% (OF-5), then each group was fed for 3 weeks. Plasma total cholesterol, non-esterified fatty acids (NEFA), total cholesterol, low density lipoprotein (LDL), very low density lipoprotein (VLDL) were decreased significantly (p<0.05) in OF-5 group compared to DC, but high density lipoprotein (HDL) was not changed. AST and ALT were also reduced and bile acid excretion was improved. Composition of urine in OF-5 was almost same in NC. The expression of cholesterol $7{\alpha}$-hydroxylase (CYP7A1), 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA-R), Low density lipoprotein receptor (LDL-R) mRNA indicated that feeding OF have the effects of cholesterol decreation in plasma by synthesis of bile acid from cholesterol. These results provide experimental evidence about improved lipid metabolism of the OF feeding in the STZ-induced diabetic rats.

• Journal of Oriental Neuropsychiatry
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• v.23 no.2
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• pp.49-58
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• 2012

Objectives : The purpose of this study is to examine the effects of Mindfulness-based concentration qigong for children (MBCQ-C) in healthy children with subjective poor attention. Methods : This study examined the effects of MBCQ-C on healthy children with subjective poor attention, who vistied Korean medicine hospital neuropsychiatry outpatient clinic. The MBCQ-C was practiced with 11 participants, 2 of them quit in the middle of the program, and hence, they were excluded for data analysis. MBCQ-C consisted of 8 sessions, and each session took about 60 minutes. The outcome measurement was Frankfurter Aufmerksamkeits-Inventar (FAIR), which measured selective attention, self-control and sustained attention. Results : The results of this study showed that selective attention, and sustained attention were significantly improved. Self-control also improved, but without any statistical significance. These results indicate MBCQ-C was effective for the improvement of attention abilities, but self-control, including upper cognition area needs more consistent exercise. Conclusions : The MBCQ-C consisting of 8 sessions were shown to be an effective intervention in improving the attention abilities of healthy children with subjective poor attention.

• Structural Engineering and Mechanics
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• v.44 no.6
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• pp.815-837
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• 2012

A plated beam is strengthened by bonding a thin plate to the tension face; it often fails because of premature debonding of the thin plate from the original beam in a brittle manner. A sound understanding of the mechanism of such debonding failure is very important for the effective use of this strengthening technique. This paper presents an improved analytical solution for interfacial stresses that incorporates multiple loading conditions simultaneously, including prestress, mechanical and thermal loads, and the effects of adherend shear deformations and curvature mismatches between the beam and the plate. Simply supported beams bonded with a thin prestressing plate and subjected to both mechanical and thermal loading were considered in the present work. The effects of the curvature mismatch and adherend shear deformations of the beam and plate were investigated and compared. The main mechanisms affecting the distribution of interfacial stresses were analyzed. Both the normal and shear stresses were found to be significantly influenced by the coupled effects of the elastic moduli with the ratios $E_a/E_b$ and $E_a/E_p$.

• Korean Journal of Child Studies
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• v.32 no.1
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• pp.1-11
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• 2011

This aim of this study was to investigate the effects of the music appreciation teaching-learning method on the musical ability of young children. The music appreciation activities were developed firstly in consideration of the 4 steps of the learning cycle (recognition, exploration, inquiry, application). One group was then taught music appreciation, taking into account the learning cycle. The results were then compared with another comparative group in terms of musical ability. The results indicated that the musical ability sum of the treatment groups improved more than the comparative group. More specifically, the treatment group for four-year-olds was seen to have improved significantly more than the comparative group in terms of musical ability. These results indicate that this music appreciation teaching-learning method has a number of positive effects upon young children`s musical ability. Therefore, it is suggested that kindergarten teachers conduct instruction with an appropriate accompanying learning cycle as part of the teaching-learning method when it comes to improving the musical ability of young children.