The ultimate goal of total artificial heart is permanent substitute for a failed heart in a patient without any other therapeutic modality. Until now, infection has been the main problem related to the mechanical circulatory support system. The best way to solve this catastrophic complication and to improve the quality of life of TAH patients in terms of tethering must be implantation of TAH totally. The EH-TAH has been developed in NCVC from 1987 for this purpose. The system consists of an energy converter and pumps, which are designed to be placed in abdomen and pericardial space separately for a good anatomical fit. To evaluate the anatomical fit and hemodynamic performance of the EH-TAH, in vivo test was done. General condition of the animal and hemodynamic status had been stable until the TAH stopped on the 11th pumping day. The estimated cardiac output was about 7.7L/min. The values of mean aortic pressure, left and right atrial pressure were 93$\pm$10, 19$\pm$3 and 15$\pm$4 mmHg, respectively. The correlation coefficient between left and right atrial pressure was 0.96, which represents the dynamic function of the interatrial shunt in controlling left-right imbalance of cardiac output. During pumping days, the temperature on the surface of actuator had been maintained at 39.7$\pm$0.4$^{\circ}C$, less than 1$^{\circ}C$ higher than the rectal temperature. The TAH stopped on the 11th day due to mechanical problems. We concluded that the EH-TAH possessed satisfactory basic performance including anatomic fit and hemodynamic adequacy, although there were several mechanical problems to be solved yet.
The purpose of this study was twofold; one was to investigate the elderly people's educational needs on successful aging(Study 1), and the other was to construct the educational program for successful aging and evaluate its effectiveness(Study 2). For Study 1, data were collected with structured questionnaires from the 166 elderly people participating in the government job creation projects for the aged in Gwangju and analyzed using frequency analysis and means-of-different tests. It was found that most of the elderly people strongly desired the education successful aging in terms of health care, finance, social participation, leasure, social network and self acceptance. In Study 2, the educational program for successful aging was constructed based on the results of Study 1 and the effectiveness of the program was evaluated using one-group pretest-posttest experimental design. Data were collected from 34 voluntary participants in the program before and after the implementation of the program and analyzed using the paired samples t-test technique. It was found that the program had a positive effect on the improvement of the elderly people's understanding of successful aging in terms of health care, finance, social participation, leasure, social network and self acceptance. Based on these results, the implementation of the educational program designed in this study was recommended to improve the elderly people's quality of life and the directions for future research were advanced. successful aging, educational needs, educational program, effectiveness.
Background: As the population rapidly ages, older adults are increasingly likely to experience mobility problems. This study aims to explore the characteristics related to an elderly person's willingness to live in a nursing home if they have mobility problems Methods: This study analyzed data from 9,917 older adults (5,976 young-old and 3,941 old-old) obtained from the 2020 National Survey of Older Koreans. The dependent variable was the intended place of residence for older adults with mobility problems. Independent variables included various characteristics: (1) sociodemographic and social support, (2) health and functional status, and (3) residential environment. Rao-Scott chi-square tests and survey logistic regression analyses were performed for the young-old and old-old, respectively. Results: The intention to live in a nursing home was significantly different between the young-old (30.4%) and the old-old (34.7%) (p=0.009). According to fully adjusted multivariable analyses, for the young-old, the odds ratio of intending to live in a nursing home was significantly higher in social security benefit recipients (1.45; 95% confidence interval [CI], 1.06-1.97) compared to other individuals. The odds ratio was higher in unmarried (divorced, separated, widowed, or never-married) individuals for both young-old (1.41; 95% CI, 1.22-1.63) and old-old (1.34; 95% CI, 1.09-1.65) age groups, compared to their respective married counterparts. Conclusion: The results of this study suggest that in an aging society, health and social policies should be designed considering the different characteristics of the elderly to improve their health, function, and quality of life.
Objectives : Oral care is important for workers and Korean adults to improve the quality of life and perform economic activities. This study was conducted to prepare the basic data to establish the management system for adult oral health by looking into characteristics by ages and the genders questingly. Methods : Oral health examination was conducted on workers in 2009 in the city of Gwangju and Chonnam province. This analysis was extracted using SPSS(SPSS 12.0 for windows, SPSS Inc, Chicago, USA). Results : Among the study respondents, 39.5% workers and 47.7% Korean adults answered their subjective oral health is not good, but there was no statistically significant difference between them(p< $0.001^{***}$). 39.9% workers and 2 0.6% Korean adults were smokers, and they showed a statistically significance in the ages and genders (p< $0.001^{***}$). 91.2 %workers and 49.8% Korean adults brushed their teeth before going to bed, and they showed a statistically significance in the ages and genders(p< $0.001^{***}$). In terms of the gender, male workers and Korean female adults showed high frequency of use, and both workers and Korean adults aged 18-24 showed high frequency with regard to the age. Regarding the use of oral care items, 36.0% workers and 16.9% Korean adults used them, and a statistical significance was shown in both the gender and age(p< $0.001^{***}$). In terms of the gender, female workers and Korean female adults showed high frequency of use and in terms of the age, 45-54 age bracket workers and 30-34age bracket Korean adults used the items frequently. 28.0% workers and 30.7% Korean adults answered that their mastication among oral functions is uncomfortable, and 8.8% workers and 6.5% Korean adults responded that it is hard to pronounce. They were statistically significant in the gender and age(p< $0.001^{***}$). Workers and Korean female adults expressed their mastication discomfort and men expressed that they have a difficulty in pronouncing. In terms of the age, the 54-64 age bracket workers and Korean adults express their inconvenience of mastication and pronunciation. Conclusions : According to the above findings, it needs to build the economical and efficient adult oral health care system in order to enhance both workers and Korean adults' oral health.
Journal of the Korea Academia-Industrial cooperation Society
/
v.18
no.4
/
pp.293-303
/
2017
Thus study examined the possible the link between social enterprises and lifelong education for the underprivileged. To this end, this study searched for the definition and position of social enterprises emerging from the welfare system under the influence of neoliberalism and overcoming the problems in terms of creating social jobs and providing welfare services. In addition, the lifelong education for the underprivileged was examined according to the subjects, such as the disabled, migrant women, young and adult low-income group, and senior citizens. The plan was as follows. First, the expansion of the proportion of community-affiliated social enterprises was analyzed. Second, it provides a differentiated support and protection market for social enterprise. Third, the development and dissemination of social entrepreneur training programs was examined. The results showed that the entire society should have a sense of responsibility for the support of the underprivileged. This provides implications for the linkage of lifelong education and social enterprise in the expansion possibility to improve the quality of life and expand lifelong education for the underprivileged.
Naini, M Alizade;Mokarram, P;Kavousipour, S;Zare, N;Atapour, A;Zarin, M Hassan;Mehrabani, G;Borji, M
Asian Pacific Journal of Cancer Prevention
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v.17
no.4
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pp.2185-2193
/
2016
Background: The pathogenesis of sporadic colorectal cancer (CRC) is influenced by the patient genetic background and environmental factors. Based on prior understanding, these are classified in two major pathways of genetic instability. Microsatellite instability (MSI) and CPG island methylator phenotype (CIMP) are categorized as features of the hypermethylated prototype, and chromosomal instability (CIN) is known to be indicative of the non-hypermethylated category. Secreted frizzled related protein 2 (SFRP2), APC1A in WNT signaling pathway and the DNA repair gene, O6-methylguanine-DNA methyltransferase (MGMT), are frequently hypermethylated in colorectal cancer. Detection of methylated DNA as a biomarker by easy and inexpensive methods might improve the quality of life of patients with CRC via early detection of cancer or a precancerous condition. Aim: To evaluate the rate of SFRP2 and MGMT hypermethylation in both polyp tissue and serum of patients in south Iran as compared with matched control normal population corresponding samples. Materials and Methods: Methylation-specific PCR was used to detect hypermethylation in DNA extracted from 48 polypoid tissue samples and 25 healthy individuals. Results: Of total polyp samples, 89.5% had at least one promoter gene hypermethylation. The most frequent methylated locus was SFRP2 followed by MGMT-B (81.2 and 66.6 percent respectively). Serologic detection of hypermethylation was 95% sensitive as compared with polyp tissue. No hypermethylation was detected in normal tissue and serum and its detection in patients with polyps, especially of serrated type, was specific. Conclusions: Serologic investigation for detection of MGMT-B, SFRP2 hypermethylation could facilitate prioritization of high risk patients for colonoscopic polyp detection and excision.
Journal of the Korea Academia-Industrial cooperation Society
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v.18
no.12
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pp.744-754
/
2017
In this study, an analytic hierarchy process (AHP) was conducted with the aim of developing a post-disaster refugee housing performance index system (PPS) to improve the post-disaster refugee housing (PRH) performance criteria for the foundation of quality-based development. The PRH was defined as a mid-term temporary housing facility that is used for a certain period before the permanent housing is established. The safety, rapidity, reusability, habitability, and economy were derived from major performance factors through prior research. A hierarchical PPS was organized by linking the major performance factors with the whole life cycle process of PRH. The priority of each performance index of PPS was determined quantitatively using the analytic hierarchy process through an expert survey. Based on AHP analysis, the performance criterion of the total weight 1-10 ranking and the performance criterion of the first rank in each category were classified into the essential performance criterion (must be achieved) and the others were classified into the recommended performance criterion (optional achieved) and the performance index was constructed considering all stages of PRH development. With the completion of the PRH performance index, it is expected that victims will be able to secure stable residence and return to their daily lives quickly.
Sleep is an essential factor for living a healthy life, but most modern people complain of poor sleep. For these people, as the need for a means to simply evaluate and manage the quality of sleep increases, devices that can check the sleep state at home without monitoring by an examiner are being developed. The smart sleep mask, which is the subject of this usability test, provides bio-signal monitoring while sleeping so that you can conveniently measure and manage your sleep state for yourself. The purpose of this study is to evaluate the usability and safety of the smart sleep mask, to find and prevent potential factors related to errors in use that may occur, and to develop the comfort and safety of this product. As a result of the formative evaluation of the sleep mask prototype, it was reported that it was difficult to turn on the power and check the results, and that the sleep mask was not comfortable to wear. Different opinions were presented on the size and weight of the sleeping mask by people in different age groups.
Journal of Korea Entertainment Industry Association
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v.13
no.7
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pp.497-503
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2019
The purpose of this study was to investigate the effect of self care training program on motor function of upper limb and self-efficacy in chronic stroke patients. This study selected 20 chronic stroke patients in local community men. The subjects carried out self care training program be composed of task oriented training for 40 minutes, 4 times per week for 6 weeks. Manual function test(MFT), digital grip dynamometer, self-efficacy scale were used to evaluate motor function of upper limb and self-efficacy during pre and post intervention. In MFT and hand grip force test, the post outcome were significantly increase than the pre outcome(p<.05). In self-efficacy evaluation, the post outcome of was significantly improve than the pre outcome(p<.05). The result of this study show that the self care training program be composed of task oriented training may be appropriate for improving the motor function of upper limb and self-efficacy in chronic stroke patients. This will enable the application of self care training program in rehabilitation therapy of chronic stroke patients and it will help guide the selection of the therapist as one therapeutic basis
Objectives : This study aimed to determine self-esteem and oral health impact profile (OHIP) of orthodontic patients to get data necessary for the process of consultation, education, and treatment for those patients who hoped to get orthodontic therapy in order to see effects of orthodontic therapy on personal life in consideration of general characteristics of those patients under orthodontic therapy. methods : A self-administered questionnaire was used among 232 outpatients under orthodontic therapy from October to November 2009, obtaining the following results. Results : 1. As for general characteristics of respondents, those under 19 years of age constituted 46.6%; the unmarried comprised 85.8%; and students constituted 53.4%. 2. Most respondents were getting orthodontic therapy for beauty (41.8%) and dental health (40.5%). Family (54.3%) contributed to their decision to get orthodontic therapy; parents or siblings (62.5%) were bearing the treatment expenses. 3. Females were getting orthodontic therapy for an aesthetic purpose (50.3%), and male for the purpose of dental health (44.6%) (P<0.01). 4. OHIP was slightly higher among males ($4.10{\pm}0.61$) than among female ($4.00{\pm}0.78$), and was highest among those 19 years old and under ($4.17{\pm}0.67$); the older they were, the lower it was significantly (P<0.05). Most of them were earning 3 to 4 million won ($4.22{\pm}0.72$); the married ($4.05{\pm}0.74$) constituted higher percentage. As for occupation, students ($4.13{\pm}0.66$) comprised the highest percentage. 5. Self-esteem was higher among males ($3.83{\pm}0.47$) than among females ($3.80{\pm}0.50$), and was highest among those 25 to 29 years old ($3.92{\pm}0.46$). Most of them were earning more than 5 million won ($3.91{\pm}0.42$), which was statistically significant (P<0.01). The married ($3.91{\pm}0.54$) constituted higher percentage than the unmarried ($3.80{\pm}0.48$); office managers ($3.95{\pm}0.55$) comprised the highest percentage. 6. As for correlation between variables effecting OHIP of orthodontic patients, there was negative correlation in age (r=-0.225) and positive correlation in occupation (r=0.122). As for correlation between variables effecting self-esteem of orthodontic patients, there was negative correlation in occupation (r=-0.130) and positive correlation n income (0.126), while there was positive correlation (r=0.202) between OHIP and self-esteem of orthodontic patients. Conclusions : Younger orthodontic patients who were students showed higher OHIP, and professionals earning more showed higher self-esteem. Orthodontic patients with higher OHIP showed higher self-esteem. Therefore, it is necessary to develop a program based on OHIP and self-esteem in consulting and treating orthodontic patients; since it is considered that orthodontic therapy will improve appearance, enhance self-confidence, and have positive effects on interpersonal relationships and quality of living, researches are necessary on constant changes in psychological properties.
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