• 제목/요약/키워드: Importance sampling method

검색결과 207건 처리시간 0.029초

A Solid-state NMR Study of the Kinetics of the Activity of an Antimicrobial Peptide, PG-1 on Lipid Membranes

  • Kim, Chul;Wi, Sungsool
    • Bulletin of the Korean Chemical Society
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    • 제33권2호
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    • pp.426-432
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    • 2012
  • The activity of an antimicrobial peptide, protegrin-1 (PG-1), on lipid membranes was investigated using solidstate NMR and a new sampling method that employed mechanically aligned bilayers between thin glass plates. At 95% hydration and full hydration, the peptide respectively disrupted 25% and 86% of the aligned 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphotidylcholine (POPC) bilayers at a P/L (peptide-to-lipid) ratio of 1/20 under the new experimental conditions. The kinetics of the POPC bilayers disruption appeared to be diffusioncontrolled. The presence of cholesterol at 95% hydration and full hydration reduced the peptide disruption of the aligned POPC bilayers to less than 10% and 35%, respectively. A comparison of the equilibrium states of heterogeneously and homogeneously mixed peptides and lipids demonstrated the importance of peptide binding to the biomembrane for whole membrane disruption.

노인공동생활주택에의 입주의사 결정요인 분석 (A Study on the Determinant Factor of Intention to Move into Senior Congregate Housing)

  • 유병선;홍형옥
    • 한국주거학회논문집
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    • 제16권2호
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    • pp.99-105
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    • 2005
  • Due to the vast increase in the elderly population and the changes in traditional filial duties, the importance of the elderly living arrangement is being greatly emphasized. The purpose of this study was to analyse the determinant factor of intention to move into senior congregate housing. The survey was conducted among middle-aged people in their fifties, who lived in Seoul, using the systematic random sampling method. The final sample included 498 respondents. The results were as follows. 1) It was revealed that many respondents thought positively about senior congregate housing. Both of having children and income were proved as an important variables which had an impact factor to move into senior congregate housing. 2) It was found that residential environment was the more important factor than housing level itself or personal social environment.

Bayesian Model Selection for Nonlinear Regression under Noninformative Prior

  • Na, Jonghwa;Kim, Jeongsuk
    • Communications for Statistical Applications and Methods
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    • 제10권3호
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    • pp.719-729
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    • 2003
  • We propose a Bayesian model selection procedure for nonlinear regression models under noninformative prior. For informative prior, Na and Kim (2002) suggested the Bayesian model selection procedure through MCMC techniques. We extend this method to the case of noninformative prior. The difficulty with the use of noninformative prior is that it is typically improper and hence is defined only up to arbitrary constant. The methods, such as Intrinsic Bayes Factor(IBF) and Fractional Bayes Factor(FBF), are used as a resolution to the problem. We showed the detailed model selection procedure through the specific real data set.

다중샘플링 다중작업을 수행하는 실시간제어시스템의 시계수제한성 유도 (Derivation of the Timing Constraints for Multi-Sampled Multitasks in a Real-Time Control System)

  • 이대현;김학배
    • 제어로봇시스템학회논문지
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    • 제5권2호
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    • pp.145-150
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    • 1999
  • A real-time control system, composed of the controlled processor and the controller computer(s), may have a variety of task types, some of which have tight timing-constraints in generating the correct control input. The maximum period of those task failures tolerable by the system is called the hard deadline, which depends on not only fault characteristics but also task characteristics. In the paper, we extend a method deriving the hard deadline in LTI system executing single task. An algorithm to combine the deadlines of all the elementary tasks in the same operation-mode is proposed to derive the hard deadline of the entire system. For the end, we modify the state equation for the task to capture the effects of task failures (delays in producing correct values) and inter-correlation. We also classify the type of executing the tasks according to operation modes associated with relative importance of correlated levels among tasks, into series, parallel, and cascade modes. Some examples are presented to demonstrate the effectiveness of the proposed methods.

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자료 분석의 기초 (An Introduction to Data Analysis)

  • 박선일;이영원
    • 한국임상수의학회지
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    • 제26권3호
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    • pp.189-199
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    • 2009
  • With the growing importance of evidence-based medicine, clinical or biomedical research relies critically on the validity and reliability of data, and the subsequent statistical inferences for medical decision-making may lead to valid conclusion. Despite widespread use of analytical techniques in papers published in the Journal of Veterinary Clinics statistical errors particularly in design of experiments, research methodology or data analysis methods are commonly encountered. These flaws often leading to misinterpretation of the data, thereby, subjected to inappropriate conclusions. This article is the first in a series of nontechnical introduction designed not to systemic review of medical statistics but intended to provide the journal readers with an understanding of common statistical concepts, including data scale, selection of appropriate statistical methods, descriptive statistics, data transformation, confidence interval, the principles of hypothesis testing, sampling distribution, and interpretation of results.

공동주택 거푸집공사 작업량 분석에 따른 개선 방안에 대한 연구 (Suggestion improvement measures based on form work productivity analysis in apartment housing construction)

  • 윤자영;김영석;김재준
    • 한국건축시공학회지
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    • 제10권1호
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    • pp.49-56
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    • 2010
  • 건설산업은 타 산업분야에 비하여 체계화되지 못하고 경험 또는 관습에 의한 의사결정이 이루어지는 경우가 빈번하여 생산성 향상이 적극적으로 이루어지지 못하고 있는 실정이다. 특히, 대단위의 건설생산이 이루어지고 있는 공동주택의 공사에서 생산성 향상을 위한 과학적이고 분석적인 연구가 수행될 경우 그 파급효과가 대단히 클 것으로 기대된다. 따라서 본 논문에서는 공사원가에 가장 큰 영향을 미치는 공동주택 골조공사 중 주요공종인 거푸집공사의 효율적인 생산성 향상을 위한 공법개선안을 제시하고자 생산성 측정기법으로 워크샘플링을 활용하였다. 기존 거푸집공사에 대하여 작업절차를 분석하고, 각각의 작업별로 생산성을 분석하였다. 기존 작업법에서 분석된 문제점을 기반으로 개선방안을 제안하였다.

Influence of Human Resources, Financial Attitudes, and Coordination on Cooperative Financial Management

  • ATMADJA, Anantawikrama Tungga;SAPUTRA, Komang Adi Kurniawan;TAMA, Gede Mandirta;PARANOAN, Selmita
    • The Journal of Asian Finance, Economics and Business
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    • 제8권2호
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    • pp.563-570
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    • 2021
  • The importance of cooperative financial management is expected to be able to encourage the needs of the community especially towards the supervision of cooperatives and human resources. The study was conducted aiming to determine the effect of human resources, financial attitudes, and coordination on cooperative financial management. Research with quantitative methods. The study was conducted with multiple regression methods, while the sampling technique was based on a random sample of samples with the data collection method using a survey method in the form of a questionnaire that was measured with a Likert scale. The method of determining the research sample is done by calculating the Slovin formula, determining the research sample of 166 cooperatives in Buleleng Regency, Bali Province. The results of the research prove that partial human resources have a significant positive effect on cooperative financial management, financial attitude variables have a significant positive effect on cooperative financial management and coordination variables have a significant positive effect on cooperative financial management. The results of this study can be stated that the better the financial management of cooperatives, better will be the impact on cooperative growth so that the need for more competent resources in cooperative management.

내.외과계 임상간호사가 인지하는 간호역할행위의 중요도와 수행도 비교 (Comparison on Perceived Importance and Frequency of Nurse's Role Behaviors between Medical and Surgical Nurses)

  • 임난영;강현숙;서문자;이여진;권성복;김동옥;김주현;박영숙;손영희;손행미;이은희;조경숙;지성애
    • 기본간호학회지
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    • 제11권2호
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    • pp.124-137
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    • 2004
  • Purpose: The purpose of this study was to examine differences in the perceived importance and frequency of nurse role behaviors for medical and surgical nurses and to examine the relationship between perceived importance and frequency of nurse role behaviors in the two groups. Method: A descriptive design was used with convenience sampling of 351 medical and surgical nurses in the 40 hospitals with over 500 beds. Data were collected using a structured questionnaire. Results: 1) The total score for perceived importance of nurse role behaviors was $4.09{\pm}.53$ for medical nurses and $4.13{\pm}.53$ for surgical nurses. 2) The total score for frequency was $3.15{\pm}.54$ for medical nurses and $3.24{\pm}.56$ for surgical nurses. 3) The perceived importance of nurse role behaviors was higher than the frequency, but the difference between two groups was not significant. 4) The perceived importance of nurse role behaviors was highly correlated with frequency (r=.579, p=.000) for the two groups. Conclusion: Medical and surgical nurses perceived the importance nurse role behavior but the frequency of the behavior is lower. Therefore, further research is needed to develop strategies to increase the frequency of nurse role behaviors.

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의료서비스 향상을 위한 병원 행정전략의 우선순위 분석 (Analytical Study on the Priority in Hospital Administrative Strategy for Improvement of Medical Service)

  • 김유호
    • 한국융합학회논문지
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    • 제10권10호
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    • pp.259-266
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    • 2019
  • 본 연구는 의료 환경의 변화로 병원의 경쟁력을 갖추기 위하여 병원의 행정전략에 대한 변화의 필요성이 있으며, 의료서비스 향상을 위해서 어떤 전략이 가장 중요한지 제시하여, 의료서비스 향상을 위한 병원 행정전략에 기초자료를 제공하고자 한다. 이를 위해서 병원행정 분야와 관련된 행정학 및 경영학 박사급 전문가 20명을 선정하였고, 자료분석방법은 AHP 방법으로 상대적 중요도를 측정하였다. 이에 대한 연구결과는 다음과 같다. 첫째, 측정영역에서 의료서비스 향상을 위한 병원 행정전략에 대한 상대적 중요도는 의료진 요인(1순위), 제반시설 요인(2순위), 직원서비스 요인(3순위), 접근편의 요인(4순위) 순으로 결과가 나타났다. 둘째, 복합가중치 분석 결과, 의료진 전문성(1순위), 의료진 다양성(2순위), 의료장비수준(3순위) 순으로 상대적 중요도가 측정되어 의료서비스 향상을 위한 병원 행정전략은 의료진의 전문성 확보, 의료진의 다양성, 그리고 의료장비 수준을 높이는 것이 가장 중요함을 알 수 있다. 이러한 결과가 의료서비스를 향상시키기 위한 병원의 행정전략 마련 시에 유용한 기초자료로 활용될 수 있을 것이며, 또한 향후 병원 행정전략 마련 시에 다각적인 요소들을 파악해야 할 것이다.

중학교 청소년의 심리적 문제와 부모와의 애착이 학교생활 적응에 미치는 영향 (The Influence of Internalization Problem and Attachment to Parents on the Adjustment to School Life in Middle School Students)

  • 최윤정
    • 아동학회지
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    • 제26권2호
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    • pp.15-25
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    • 2005
  • This research is focused on the influence of internalization problem and attachment to parents on the adjustment to school life, as well as on the attachment to parents as moderators in the influence of the process of internalization problem on the adjustment to school life. To verify the hypothesis, a survey research method was applied using stratified cluster sampling method, and focusing on middle school students in Seoul. Eleven schools were selected randomly from each of the eleven District Offices of Education in Seoul, and data were collected from 1,200 students. The data were analyzed by using the T-test and hierarchical regression methods, and the results are as follows. First, the internalization problem has negatively affected the adjustment to school life. Secondly, the moderators of the attachment to parents in the adjustment to school life were investigated. Through the above mentioned analysis, it can be deducted that, intervention with internalization problem is required in order to promote the adjustment to school life, and the importance of the attachment to parents should be addressed in the intervention for improving adjustment to school life.

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