• 대한방사성의약품학회지
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• 제8권2호
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• pp.63-70
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• 2022

The development of myocardial perfusion imaging (MPI) agents has been motivated because coronary artery disease has been one of the leading causes of death worldwide since the 1960s. Several positron emission tomography (PET) MPI agents were developed, and ¹⁸F-labeled phosphonium cations were reported actively among them. In this study, we synthesized novel ¹⁸F-labeled phosphonium cations, (5-[¹⁸F]fluoropentyl)diphenyl(pyridin-2-yl)phosphonium and (2-(2-[¹⁸F]fluoroethoxy)ethyl)diphenyl(pyridin-2-yl)phosphonium, and evaluated potential as MPI agents. Two labeled compounds were synthesized via nucleophilic substitution reactions of ¹⁸F-fluoride with the appropriate tosylate precursor in the presence of Kryptofix 2.2.2 and K₂CO₃. MicroPET studies were performed in normal rats to evaluate in vivo distribution of radiolabeled phosphonium cations for 60 min. The radiolabeled compounds were synthesized with 5%-10% yield. The radiochemical purity of labeled compounds was > 98% by analytical HPLC, and the specific activity was > 11.8 GBq/µmol. The result of microPET studies of these labeled compounds in rats showed intense uptake in the myocardium at 30 and 60 min. The results suggest that these ¹⁸F-labeled novel phosphonium cations would have potential as promising candidates for myocardial perfusion imaging.

• 전자공학회논문지SC
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• 제43권3호
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• pp.25-30
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• 2006

디지털 영상처리를 이용해 CCD 센서의 스펙트럼 응답특성을 직접 측정할 수 있는 적외선 영상기법을 제안하고 있다. 이 방법은 쉽고 경제적인 방법으로 상용 CCD 센서의 스펙트럼 감도를 검출할 수 있도록 한다. 본 장치의 핵심 부품은 단색광원기, CCD 지지대, 디지털 영상처리 시스템이 내장된 컴퓨터이다. 방법의 타당성을 증명하기 위해 상용 CCD 카메라에 대해 시험적으로 행한 실험은 이론적인 모델과 잘 일치함을 보여 주었다.

• 대한의용생체공학회:의공학회지
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• 제28권1호
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• pp.132-138
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• 2007

MR(magnetic resonance) image of moving organ such as heart shows serious distortion of MR image due to motion itself. To eliminate motion artifacts, MRI(magnetic resonance imaging) scan sequences requires a trigger pulse like ECG(electro-cardiography) R-wave. ECG-gating using cardiac cycle synchronizes the MRI sequence acquisition to the R-wave in order to eliminate image motion artifacts. In this paper, we designed ECG/PPG(photo-plethysmography) gating system which is for eliminating motion artifacts due to moving organ. This system uses nonmagnetic carbon electrodes, lead wire and shield case for minimizing RF(radio-frequency) pulse and gradient effect. Also, we developed a ECG circuit for preventing saturation by magnetic field and a finger plethysmography sensor using optic fiber. And then, gating pulse is generated by adaptive filtering based on NLMS(normalized least mean square) algorithm. To evaluate the developed system, we measured and compared MR imaging of heart and neck with and without ECG/PPG gating system. As a result, we could get a clean image to be used in clinically. In conclusion, the designed ECG/PPG gating system could be useful method when we get MR imaging of moving organ like a heart.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 1993년도 Proceedings of International Conference for Agricultural Machinery and Process Engineering
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• pp.1354-1363
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• 1993

Optical methods were developed to examine their feasibility for quality evaluation of peanut with pod. Surface color and internal quality of peanut were measured without contact. The surface color of peanut was measured by light reflectance at a region of visible wavelengths. Its characteristic was high correlated with a visual grading of peanut. A trial machine for the color grading of peanut was developed using an optical sensor and it was considered to compare with the visual grading. The spectral reflectance at a region of near infrared wavelengths from 1,200 to 2,500nm was measured , and the chemical components of peanut were related to spectral reflectance at special wavelengths. The protein, fat and moisture contents of peanut were estimated by the near infrared methods. An infrared imaging method was developed to evaluate the internal quality of peanut with pod. As thermal characteristic of peanut with pod was deeply related to internal quality , the quality of peanut can be evaluated by temperature changes on the surface of peanut. Measurement of surface color, near infrared reflectance and thermal imaging were shown to be very effective in grading of peanut with pod.

• 대한한의진단학회지
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• 제12권2호
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• pp.8-17
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• 2008

Objectives: For the traditional pulse diagnosis in Oriental Medicine, not only the pulse shape in time domain, but the width, length and depth of arterial pulse also should be measured. However, conventional pulse diagnostic systems have failed to measure the spatial parameters of the arterial pulse e.g. effective length of arterial pulse in the wrist. In fact, there are many ways to measure that kind of spatial features in arterial pulsation, but among them, the method using image sensor provides relatively cheap and simple way, therefore I tested feasibility of measuring 2-dimensional pressure distribution by imaging devices. Methods: Using widely used PC cameras and dotted balloons, the subtle oscillation of skin over the radial artery was recorded continuously, and then the displacement of every dot was calculated. Consequently, the time course of that displacements shows arterial pulse wave. Results: By the proposed method I could get pressure distribution map with 30Hz sampling rate, 21steps quantization resolution, and approximately 1mm spatial resolution. With reduced quantization resolution, $3cm{\times}4cm$ view angle could be achieved. Conclusion: Although this method has some limitations, it would be useful method for detecting 2-dimensional features of arterial pulse, and accordingly, this method provides a novel way to detect 'narrow pulse', 'wide pulse', 'long pulse', 'short pulse', and their derivatives.

• Imaging Science in Dentistry
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• 제44권2호
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• pp.155-160
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• 2014

Purpose: The purposes of this study were to develop a workstation computer that allowed intraoperative touchless control of diagnostic and surgical images by a surgeon, and to report the preliminary experience with the use of the system in a series of cases in which dental surgery was performed. Materials and Methods: A custom workstation with a new motion sensing input device (Leap Motion) was set up in order to use a natural user interface (NUI) to manipulate the imaging software by hand gestures. The system allowed intraoperative touchless control of the surgical images. Results: For the first time in the literature, an NUI system was used for a pilot study during 11 dental surgery procedures including tooth extractions, dental implant placements, and guided bone regeneration. No complications were reported. The system performed very well and was very useful. Conclusion: The proposed system fulfilled the objective of providing touchless access and control of the system of images and a three-dimensional surgical plan, thus allowing the maintenance of sterile conditions. The interaction between surgical staff, under sterile conditions, and computer equipment has been a key issue. The solution with an NUI with touchless control of the images seems to be closer to an ideal. The cost of the sensor system is quite low; this could facilitate its incorporation into the practice of routine dental surgery. This technology has enormous potential in dental surgery and other healthcare specialties.

• 전자공학회논문지
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• 제50권6호
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• pp.238-245
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• 2013

제스처 인식은 자연스러운 사용자 인터페이스를 위해 활발히 연구되는 중요한 분야이다. 본 논문에서는 키넥트 카메라로부터 입력되는 사용자의 3차원 관절(joint) 정보를 해석하여 제스처를 인식하는 방법이 제안된다. 대상으로 하는 제스처의 분포 특성에 따라 분류 트리를 설계하고 입력 패턴을 분류한다. 그리고 제스처를 리샘플링 및 정규화 하여 일정한 구간으로 나누고 각 구간의 체인코드 히스토그램을 추출한다. 트리의 각 노드별로 분류된 제스처에 다중 클래스 SVM(Multiclass Support Vector Machine)를 적용하여 학습한다. 이후 입력 데이터를 구성된 트리로 분류한 다음, 학습된 다중 클래스 SVM을 적용하여 제스처를 분류한다.

• 비파괴검사학회지
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• 제30권3호
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• pp.261-270
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• 2010

This paper presents an analytical investigation for a baseline-free imaging of a defect in plate-like structures using the time-reversal of Lamb waves. We first consider the flexural wave (A0 mode) propagation in a plate containing a defect, and reception and time reversal process of the output signal at the receiver. The received output signal is then composed of two parts: a directly propagated wave and a scattered wave from the defect. The time reversal of these waves recovers the original input signal, and produces two additional side bands that contain the time-of-flight information on the defect location. One of the side band signals is then extracted as a pure defect signal. A defect localization image is then constructed from a beamforming technique based on the time-frequency analysis of the side band signal for each transducer pair in a network of sensors. The simulation results show that the proposed scheme enables the accurate, baseline-free detection of a defect, so that experimental studies are needed to verify the proposed method and to be applied to real structure.

• 지질공학
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• 제31권4호
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• pp.479-492
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• 2021

We conducted a fundamental study on geological and rock detection via drone-based hyperspectral imaging on various types of small rock samples and interpreted the obtained information to compare and classify rocks. Further, we performed hyperspectral imaging on ten rocks, and compared the peak data value and reflectance of rocks. Results showed a difference in the reflectance and data value of the rocks, indicating that the rock colors and minerals vary or the reflectance is different owing to the luster of the surface. Among the rocks, limestone used for hyperspectral imaging is grayish white, inverted rock contains various sizes and colors in the dark red matrix, and granite comprises colorless minerals, such as white, black, gray, and colored minerals, resulting in a difference in reflectance. The reflectance of the visible ray range in ten rocks was 16.00~85.78%, in the near infrared ray range, the average reflectance was 23.94~86.43%, the lowest in basalt and highest in marble in both cases. This is because of the pores in basalt, which caused the difference in reflectance.

• 한국산업융합학회 논문집
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• 제24권6_2호
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• pp.927-935
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• 2021

This study conducted a study to improve the problems of the existing fire sensor system. In the case of the existing system, it took more than 3 minutes to detect a fire even at a short distance, making it difficult to extinguish the initial fire. In order to improve these problems, in this study, a fire detection system using an infrared thermal imaging camera was studied. The infrared image-based fire detection system is relatively wide and can detect fire over a long distance, so it has the advantage of being applicable to many fire detection systems. As a result of conducting a field test using the fire detection system, a fire that occurred about 2 km ahead was detected within about 10 seconds. Since the fire detection function of this system can detect within 10 seconds from a distance of about 2 km, it was applicable to forest fires that occur frequently in spring and autumn.