• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2375-2378
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• 2014

Cancer, like any disease, is a pathologic biological process. Drugs are designed to interfere with the pathologic process and should therefore also be validated using a functional screening method directed at these processes. Screening for cancers at an appropriate time and also evaluating results is also very important. Volumetric measurement helps in better screening and evaluation of tumors. Volumetry is a process of quantification of the tumors by identification (pre-cancerous or target lesion) and measurement. Volumetric image analysis allows an accurate, precise, sensitive, and medically valuable assessment of tumor response. It also helps in identifying possible outcomes such disease progression (PD) or complete response as per Response Evaluation Criteria in Solid Tumors (RECIST).

• Nuclear Engineering and Technology
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• v.53 no.8
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• pp.2640-2645
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• 2021

We report the development of a gamma-ray imaging device, named Large-Area Hybrid Gamma Imager (LAHGI), featuring high imaging sensitivity and good imaging resolution over a broad energy range. A hybrid collimation method, which combines mechanical and electronic collimation, is employed for a stable imaging performance based on large-area scintillation detectors for high imaging sensitivity. The system comprises two monolithic position-sensitive NaI(Tl) scintillation detectors with a crystal area of 27 × 27 cm² and a tungsten coded aperture mask with a modified uniformly redundant array (MURA) pattern. The performance of the system was evaluated under several source conditions. The system showed good imaging resolution (i.e., 6.0-8.9° FWHM) for the entire energy range of 59.5-1330 keV considered in the present study. It also showed very high imaging sensitivity, successfully imaging a 253 µCi ¹³⁷Cs source located 15 m away in 1 min; this performance is notable considering that the dose rate at the front surface of the system, due to the existence of the ¹³⁷Cs source, was only 0.003 µSv/h, which corresponds to ~3% of the background level.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.726-729
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• 2008

In this paper, we present an interference problem among elemental images in computational integral imaging reconstruction. To overcome the interference problem, we propose a method to calculate a minimum magnification factor and the preliminary experiments are performed.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.517-527
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• 1997

Magnetic Resonance Spectroscopic Imaging is a methodology combining the imaging and spectroscopy. It can provide the spectrum of each areas of image so that one can easily compare the spectrum of one position to another position of the image. In this study, we developed pulse sequence or the spectroscopic imaging method, RF wave forms or the saturation of water signal, computer simulations to validate our method, and confirmed the methodology with phantom experiment. Then we applied the spectroscopic method to human subject and identified a few important metabolites in in vivo. To develope a water saturating RF waveform, we used Shinnar-Le-Roux algorithm and obtained maximum phase RF waveform. With this RF pulse, it could suppress the water signal to 1:1000. The magnet is shimmed to under 1.0ppm with auto-shimming technique. The saturation bandwidth is 80Hz(2ppm). The water and fat seperation is 3.3ppm(about 140Hz at 1 Tesla magnet), the bandwidth is enough to resolve the difference. But we are more concerned about the narrow window in between the two peaks, in which the small quantity of metabolites reside. We performed the computer simulation and phantom experiments in 8*8 matrix form and showed good agreement in the image and spectrum. Finally we applied spectroscopic imaging to the brain of human subject. Only the lipid signal was shown in the periphery region which agrees with the at distribution in human head surface area. The spectrum inside the brain shows the important metabolites such as NAA, Cr/PCr, Choline. We here have shown the spectroscopic imaging which is normally done above 1.5 Tesla machine can be performed in the 1 Tesla Magnetic Resonance Imaging Unit.

• Investigative Magnetic Resonance Imaging
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• v.15 no.1
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• pp.57-66
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• 2011

Purpose : A new inhomogeneity correction method based on two-point Dixon sequence is proposed to obtain water and fat images at 0.35T, low field magnetic resonance imaging (MRI) system. Materials and Methods : Joint phase-magnitude density function (JPMF) is obtained from the in-phase and out-of-phase images by the two-point Dixon method. The range of the water signal is adjusted from the JPMF, and 3D inhomogeneity map is obtained from the phase of corresponding water volume. The 3D inhomogeneity map is used to correct the inhomogeneity field iteratively. Results : The proposed water-fat imaging method was successfully applied to various organs. The proposed 3D inhomogeneity correction algorithm provides good performances in overall multi-slice images. Conclusion : The proposed water-fat separation method using JPMF is robust to field inhomogeneity. Three dimensional inhomogeneity map and the iterative inhomogeneity correction algorithm improve water and fat imaging substantially.

• Journal of Biomedical Engineering Research
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• v.23 no.6
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• pp.419-430
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• 2002

In this paper. we propose an efficient method for implementing hi-directional pixel-based focusing(BiPBF) based on a sparse array imaging technique. The proposed method can improve spatial resolution and frame rate of ultrasound imaging with reduced hardware complexity by synthesizing transmit apertures with a small number of sparsely distributed subapertures. As the distance between adjacent subapertures increases, however. the image resolution tends to decrease due to the elevation of grating lobes. Such grating lobes can be eliminated in conventional synthetic aperture imaging techniques. On the contrary, grating lobes arisen from employing sparse synthetic transmit apertures can not be eliminated, which has been shown analytically in this paper. We also propose the condition and method for suppressing the grating lobes below -40dB, which is generally required in practical imaging. by placing the transmit focal depth at a near depth and properly selecting the subaperture distance in Proportion to receive aperture size. The results of both the Phantom and in vivo experiments show that the proposed method implements two-wav dynamic focusing using a smaller number of subapertures, resulting in reduced system complexity and increased frame rate.

• The Journal of the Acoustical Society of Korea
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• v.42 no.5
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• pp.422-428
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• 2023

Ultrafast ultrasound imaging has been applied to various imaging approaches, including shear wave elastography, ultrafast Doppler, and super-resolution imaging. However, these methods are still challenging in real-time implementation for three Dimension (3D) or portable applications because of their massive data rate required. In this paper, we proposed an adaptive quantization method that effectively reduces the data rate of large Radio Frequency (RF) data. In soft tissue, ultrasound backscatter signals require a high dynamic range, and thus typical quantization used in the current systems uses the quantization level of 10 bits to 14 bits. To alleviate the quantization level to expand the application of ultrafast ultrasound imaging, this study proposed a depth-sectional quantization approach that reduces the quantization errors. For quantitative evaluation, Field II simulations, phantom experiments, and in vivo imaging were conducted and CNR, spatial resolution, and SSIM values were compared with the proposed method and fixed quantization method. We demonstrated that our proposed method is capable of effectively reducing the quantization level down to 3-bit while minimizing the image quality degradation.

• Journal of Korea Multimedia Society
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• v.15 no.10
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• pp.1264-1272
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• 2012

Three-dimensional volume rendering method which shows the inside of human body is widely used in medical imaging area. Existing medical imaging system using a volume rendering method already has provided a variety of three-dimensional results. Recently existing results in the medical imaging among physicians and patients to facilitate communication have been studied since smart device which has advantage of portability applied in the medical imaging. In this paper, we propose 3D volume visualization system for a relatively low spec portable smart devices by using 2D textures and we also implements 2D diagnostic images of portable medical imaging visualization system.

• International Journal of Contents
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• v.5 no.4
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• pp.30-34
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• 2009

Many studies have been done on the integral imaging pickup whose objective is to get efficiently elemental images from a lens array with respect to three-dimensional (3D) objects. In the integral imaging pickup process, it is necessary to render an elemental image from each elemental lens in a lens array for 3D objects, and then to combine them into one total image. The multiple viewpoint rendering (MVR) is one of various methods for integral imaging pickup. This method, however, has the computing and rendering time problem for obtaining element images from a lot of elemental lens. In order to solve the problems, in this paper, we propose a parallel MVR (PMVR) method to generate elemental images in a parallel through distribution of elemental lenses into multiple threads simultaneously. As a result, the computation time of integral imaging using PMVR is reduced significantly rather than a sequential approach and then we showed that the PMVR is very useful.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2003.11a
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• pp.412-414
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• 2003

This paper is about research of scintillator layer, which is used for Hybrid method to increase electric signals in a-Se, the material of Direct method. In case of the thermal evaporation, CsI has column structure which is an disadvantage as scintillator. But it decreases scattering of incident X-ray, has better Light output intensity than other scintillation materials. CsI was made by Thermal evaporation. The Doping material, Na, 0.1, 0.3, 0.5, 0.7g were added in each sample. Analysis of absorbed wavelength, PL(Photoluminescence), Light output intensity, SEM, and XRD analysis were performed to analyze optical characteristics. Doping rate of CsI:Na to use as scintillation layer in a-Se based detector could be optimized.