• Journal of Radiopharmaceuticals and Molecular Probes
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• v.8 no.2
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• pp.63-70
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• 2022

The development of myocardial perfusion imaging (MPI) agents has been motivated because coronary artery disease has been one of the leading causes of death worldwide since the 1960s. Several positron emission tomography (PET) MPI agents were developed, and ¹⁸F-labeled phosphonium cations were reported actively among them. In this study, we synthesized novel ¹⁸F-labeled phosphonium cations, (5-[¹⁸F]fluoropentyl)diphenyl(pyridin-2-yl)phosphonium and (2-(2-[¹⁸F]fluoroethoxy)ethyl)diphenyl(pyridin-2-yl)phosphonium, and evaluated potential as MPI agents. Two labeled compounds were synthesized via nucleophilic substitution reactions of ¹⁸F-fluoride with the appropriate tosylate precursor in the presence of Kryptofix 2.2.2 and K₂CO₃. MicroPET studies were performed in normal rats to evaluate in vivo distribution of radiolabeled phosphonium cations for 60 min. The radiolabeled compounds were synthesized with 5%-10% yield. The radiochemical purity of labeled compounds was > 98% by analytical HPLC, and the specific activity was > 11.8 GBq/µmol. The result of microPET studies of these labeled compounds in rats showed intense uptake in the myocardium at 30 and 60 min. The results suggest that these ¹⁸F-labeled novel phosphonium cations would have potential as promising candidates for myocardial perfusion imaging.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.43 no.3 s.309
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• pp.25-30
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• 2006

An infrared imaging method is proposed in which direct measurement of the spectral response of CCD sensors can be achieved through digital image processing. This method allows for a simple and economic method to detect the spectral sensitivity of commercialized CCD sensors. The key components of the apparatus are a monochromator, CCD-sample supporter and a personal computer equipped with a digital image processing systems. Tentative experimentation conducted on the commercialized CCD camera has resulted in a fairly consistent agreement with the theoretical model.

• Journal of Biomedical Engineering Research
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• v.28 no.1
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• pp.132-138
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• 2007

MR(magnetic resonance) image of moving organ such as heart shows serious distortion of MR image due to motion itself. To eliminate motion artifacts, MRI(magnetic resonance imaging) scan sequences requires a trigger pulse like ECG(electro-cardiography) R-wave. ECG-gating using cardiac cycle synchronizes the MRI sequence acquisition to the R-wave in order to eliminate image motion artifacts. In this paper, we designed ECG/PPG(photo-plethysmography) gating system which is for eliminating motion artifacts due to moving organ. This system uses nonmagnetic carbon electrodes, lead wire and shield case for minimizing RF(radio-frequency) pulse and gradient effect. Also, we developed a ECG circuit for preventing saturation by magnetic field and a finger plethysmography sensor using optic fiber. And then, gating pulse is generated by adaptive filtering based on NLMS(normalized least mean square) algorithm. To evaluate the developed system, we measured and compared MR imaging of heart and neck with and without ECG/PPG gating system. As a result, we could get a clean image to be used in clinically. In conclusion, the designed ECG/PPG gating system could be useful method when we get MR imaging of moving organ like a heart.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 1993.10a
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• pp.1354-1363
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• 1993

Optical methods were developed to examine their feasibility for quality evaluation of peanut with pod. Surface color and internal quality of peanut were measured without contact. The surface color of peanut was measured by light reflectance at a region of visible wavelengths. Its characteristic was high correlated with a visual grading of peanut. A trial machine for the color grading of peanut was developed using an optical sensor and it was considered to compare with the visual grading. The spectral reflectance at a region of near infrared wavelengths from 1,200 to 2,500nm was measured , and the chemical components of peanut were related to spectral reflectance at special wavelengths. The protein, fat and moisture contents of peanut were estimated by the near infrared methods. An infrared imaging method was developed to evaluate the internal quality of peanut with pod. As thermal characteristic of peanut with pod was deeply related to internal quality , the quality of peanut can be evaluated by temperature changes on the surface of peanut. Measurement of surface color, near infrared reflectance and thermal imaging were shown to be very effective in grading of peanut with pod.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.12 no.2
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• pp.8-17
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• 2008

Objectives: For the traditional pulse diagnosis in Oriental Medicine, not only the pulse shape in time domain, but the width, length and depth of arterial pulse also should be measured. However, conventional pulse diagnostic systems have failed to measure the spatial parameters of the arterial pulse e.g. effective length of arterial pulse in the wrist. In fact, there are many ways to measure that kind of spatial features in arterial pulsation, but among them, the method using image sensor provides relatively cheap and simple way, therefore I tested feasibility of measuring 2-dimensional pressure distribution by imaging devices. Methods: Using widely used PC cameras and dotted balloons, the subtle oscillation of skin over the radial artery was recorded continuously, and then the displacement of every dot was calculated. Consequently, the time course of that displacements shows arterial pulse wave. Results: By the proposed method I could get pressure distribution map with 30Hz sampling rate, 21steps quantization resolution, and approximately 1mm spatial resolution. With reduced quantization resolution, $3cm{\times}4cm$ view angle could be achieved. Conclusion: Although this method has some limitations, it would be useful method for detecting 2-dimensional features of arterial pulse, and accordingly, this method provides a novel way to detect 'narrow pulse', 'wide pulse', 'long pulse', 'short pulse', and their derivatives.

• Imaging Science in Dentistry
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• v.44 no.2
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• pp.155-160
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• 2014

Purpose: The purposes of this study were to develop a workstation computer that allowed intraoperative touchless control of diagnostic and surgical images by a surgeon, and to report the preliminary experience with the use of the system in a series of cases in which dental surgery was performed. Materials and Methods: A custom workstation with a new motion sensing input device (Leap Motion) was set up in order to use a natural user interface (NUI) to manipulate the imaging software by hand gestures. The system allowed intraoperative touchless control of the surgical images. Results: For the first time in the literature, an NUI system was used for a pilot study during 11 dental surgery procedures including tooth extractions, dental implant placements, and guided bone regeneration. No complications were reported. The system performed very well and was very useful. Conclusion: The proposed system fulfilled the objective of providing touchless access and control of the system of images and a three-dimensional surgical plan, thus allowing the maintenance of sterile conditions. The interaction between surgical staff, under sterile conditions, and computer equipment has been a key issue. The solution with an NUI with touchless control of the images seems to be closer to an ideal. The cost of the sensor system is quite low; this could facilitate its incorporation into the practice of routine dental surgery. This technology has enormous potential in dental surgery and other healthcare specialties.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.6
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• pp.238-245
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• 2013

Gesture recognition has been widely one of the research areas for natural user interface. This paper presents a novel gesture recognition method using tree classification and multiclass SVM(Support Vector Machine). In the learning step, 3D trajectory of human gesture obtained by a Kinect sensor is classified into the tree nodes according to their distributions. The gestures are resampled and we obtain the histogram of the chain code from the normalized data. Then multiclass SVM is applied to the classified gestures in the node. The input gesture classified using the constructed tree is recognized with multiclass SVM.

• Journal of the Korean Society for Nondestructive Testing
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• v.30 no.3
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• pp.261-270
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• 2010

This paper presents an analytical investigation for a baseline-free imaging of a defect in plate-like structures using the time-reversal of Lamb waves. We first consider the flexural wave (A0 mode) propagation in a plate containing a defect, and reception and time reversal process of the output signal at the receiver. The received output signal is then composed of two parts: a directly propagated wave and a scattered wave from the defect. The time reversal of these waves recovers the original input signal, and produces two additional side bands that contain the time-of-flight information on the defect location. One of the side band signals is then extracted as a pure defect signal. A defect localization image is then constructed from a beamforming technique based on the time-frequency analysis of the side band signal for each transducer pair in a network of sensors. The simulation results show that the proposed scheme enables the accurate, baseline-free detection of a defect, so that experimental studies are needed to verify the proposed method and to be applied to real structure.

• The Journal of Engineering Geology
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• v.31 no.4
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• pp.479-492
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• 2021

We conducted a fundamental study on geological and rock detection via drone-based hyperspectral imaging on various types of small rock samples and interpreted the obtained information to compare and classify rocks. Further, we performed hyperspectral imaging on ten rocks, and compared the peak data value and reflectance of rocks. Results showed a difference in the reflectance and data value of the rocks, indicating that the rock colors and minerals vary or the reflectance is different owing to the luster of the surface. Among the rocks, limestone used for hyperspectral imaging is grayish white, inverted rock contains various sizes and colors in the dark red matrix, and granite comprises colorless minerals, such as white, black, gray, and colored minerals, resulting in a difference in reflectance. The reflectance of the visible ray range in ten rocks was 16.00~85.78%, in the near infrared ray range, the average reflectance was 23.94~86.43%, the lowest in basalt and highest in marble in both cases. This is because of the pores in basalt, which caused the difference in reflectance.

• Journal of the Korean Society of Industry Convergence
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• v.24 no.6_2
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• pp.927-935
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• 2021

This study conducted a study to improve the problems of the existing fire sensor system. In the case of the existing system, it took more than 3 minutes to detect a fire even at a short distance, making it difficult to extinguish the initial fire. In order to improve these problems, in this study, a fire detection system using an infrared thermal imaging camera was studied. The infrared image-based fire detection system is relatively wide and can detect fire over a long distance, so it has the advantage of being applicable to many fire detection systems. As a result of conducting a field test using the fire detection system, a fire that occurred about 2 km ahead was detected within about 10 seconds. Since the fire detection function of this system can detect within 10 seconds from a distance of about 2 km, it was applicable to forest fires that occur frequently in spring and autumn.