• 전기학회논문지
• /
• 제58권7호
• /
• pp.1450-1455
• /
• 2009

Assumed that an IPTV camera system is to be used as an ad-hoc sensor for the surveillance and diagnostics of safety-critical equipments installed in the in-containment building of the nuclear power plant, an major problem is the presence of high dose-rate gamma irradiation fields inside the one. In order to uses an IPTV camera in such intense gamma radiation environment of the in-containment building, the radiation-weakened devices including a CCD imaging sensor, FPGA, ASIC and microprocessors are to be properly shielded from high dose-rate gamma radiation using the high-density material, lead or tungsten. But the passive elements such as mirror, lens and window, which are placed in the optical path of the CCD imaging sensor, are exposed to a high dose-rate gamma ray source directly. So, the gamma-ray irradiation characteristics of the passive elements, is needed to test. A CCD camera lens, made of glass material, have been gamma irradiated at the dose rate of 4.2 kGy/h during an hour up to a total dose of 4 kGy. The radiation induced color-center in the glass lens is observed. The degradation performance of the gamma irradiated lens is explained using an color component analysis.

• 한국의학물리학회지:의학물리
• /
• 제13권1호
• /
• pp.37-43
• /
• 2002

방사선원과 감마카메라 사이에 위치한 산란매질의 종류, 두께 그리고 조준기 종류가 감마카메라 영상에 미치는 영향을 고찰하기 위하여 실험과 시뮬레이션을 수행하였다. 감마카메라는 조준기, NaI(T1) 섬광결정(60$\times$60$\times$6 ㎣), 위치민감형 광전자증배관(PSPMT), NIMs, 제어용 컴퓨터를 사용하여 개발하였다. 시뮬레이션은 산란매질(아크릴매질/공기)의 두께 변화(0～8 cm)와 조준기의 종류(평행구멍형조준기/확산형조준기) 변화에 따라 계산하였으며 실험 역시 시뮬레이션과 같은 조건으로 수행하였다. 시뮬레이션 결과를 보면, 매질의 두께가 0 cmn에서 8 cm로 증가하면, 계수율은 평행구멍형조준기의 경우 17%(공기), 60%(아크릴) 감소하였으며 확산형 조준기의 경우 감소율이 더 심하여 각각 86%(공기), 98%(아크릴)의 계수율 감소를 보였다. 실제 실험 결과도 시뮬레이션 결과와 비슷하게 매질의 두께가 0 cm에서 8 cm로 증가하면 평행구멍형조준기의 경우 계수율은 10%(공기), 54%(아크릴) 감소하였으며 확산형조준기의 경우 36%(공기), 63%(아크릴)의 계수율 감소를 보였다. 영상의 공간분해능 역시 매질의 두께가 증가할수록 저하되었다. 연구결과 소형 감마카메라를 임상적으로 사용하고자 할 때 감마카메라를 질환 부위에 최대한 밀착시키고 산란매질 두께를 최소화해야 고효율, 고분해능 영상을 얻을 수 있음을 확인하였다.

• 한국의학물리학회지:의학물리
• /
• 제6권1호
• /
• pp.65-77
• /
• 1995

A new gamma camera using a-Si : H photodetectors has been designed for the imaging of heart and other small organs. In this new design the photomultiplier tubes and the position sensing circuitry are replaced by 2-D array of a-Si : H p-i-n pixel photode tectors and readout circuitry which are built on a substrate. Without the photomultiplier tubes this camera is light weight, hence can be made portable. To predict the characteristics and the performance of this new gamma camera we did Monte Carlo simulations. In the simulations 128${\times}$128 imaging array of various pixel sixes were used. $\^$99m/Tc(140keV)and $\^$201/Tl(70keV) were used as radiation sources. From the simulations we could obtain the resolution of the camera and ther overall system, and the blurring effects due to scattering in the phantom. Using the Wiener filter for image processing, restoration of the blurred image could be achieved. Simulation results of a-Si : H based gamma camera were compared with those of a conwentional gamma camera.

• Nuclear Engineering and Technology
• /
• 제51권2호
• /
• pp.439-443
• /
• 2019

To improve the noise characteristics, software-based noise reduction algorithms are widely used in cadmium zinc telluride (CZT) pixelated semiconductor gamma camera system. The purpose of this study was to develop an improved median filtering algorithm using a thresholding method for noise reduction in a CZT pixelated semiconductor gamma camera system. The gamma camera system simulated is a CZT pixelated semiconductor detector with a pixel-matched parallel-hole collimator and the spatial resolution phatnom was designed with the Geant4 Application for Tomography Emission (GATE). In addition, a noise reduction algorithm with a median filter using an improved thresholding method is developed and we applied our proposed algorithm to an acquired spatial resolution phantom image. According to the results, the proposed median filter improved the noise characteristics compared to a conventional median filter. In particular, the average for normalized noise power spectrum, contrast to noise ratio, and coefficient of variation results using the proposed median filter were 10, 1.11, and 1.19 times better than results using conventional median filter, respectively. In conclusion, our results show that the proposed median filter using improved the thresholding method results in high imaging performance when applied in a CZT semiconductor gamma camera system.

• Nuclear Engineering and Technology
• /
• 제53권4호
• /
• pp.1266-1276
• /
• 2021

The mask parameters of a coded aperture are critical design features when optimizing the performance of a gamma-ray camera. In this paper, experiments and Monte Carlo simulations were performed to derive the minimum detectable activity (MDA) when one seeks a real-time imaging capability. First, the impact of the thickness of the modified uniformly redundant array (MURA) mask on the image quality is quantified, and the imaging of point, line, and surface radiation sources is demonstrated using both cross-correlation (CC) and maximum likelihood expectation maximization (MLEM) methods. Second, the minimum detectable activity is also derived for real-time imaging by altering the factors used in the image quality assessment, consisting of the peak-to-noise ratio (PSNR), the normalized mean square error (NMSE), the spatial resolution (full width at half maximum; FWHM), and the structural similarity (SSIM), all evaluated as a function of energy and mask thickness. Sufficiently sharp images were reconstructed when the mask thickness was approximately 2 cm for a source energy between 30 keV and 1.5 MeV and the minimum detectable activity for real-time imaging was 23.7 MBq at 1 m distance for a 1 s collection time.

• 대한방사선기술학회지:방사선기술과학
• /
• 제24권2호
• /
• pp.35-40
• /
• 2001

Performance of SPECT imaging systems which use a rotating gamma camera, are affected by characteristics of the detector-collimator assembly, the data acquisition method, and the filter used in imaging reconstruction. The purpose of this study Is to examine image qualifies of SPECT with different types of low energy collimators. The SPECT imaging system in this study is a digital gamma camera system GCA-901A(Toshiba) and a data processing unit Scintipac-700(Shimadzu). The four types of collimators compared are UHR(ultra high resolution), LEHR(low energy high resolution), LEGP(low energy general purpose), and I-123 PAR(Parallel), with 0.27, 0.66, 1.00, and 2.06 relative sensitivity, respectively. In this case of the same collimators, the spatial resolutions measured in the slice plane showed a slight difference in the FWHM values(mean values of UHR, LEHR, LEGP, and I-123 PAR were 11.3 mm, 13.6 mm, 15.8 mm, and 20.4 mm, respectively) between the center and the circumference of the field of view, in the radial direction, but a large difference in the tangential direction, with lower FWHM values(values of UHR, LEHR, LEGP, and I-123 PAR were 8.4 mm, 8.7 mm, 9.3 mm, and 10.8 mm at 12 cm from the center, respectively). In comparison of SPECT images with the four types of collimators, except for the I-123 PAR collimator, image qualities of UHR, LEHR, and LEGP collimators showed only a slight difference. From the point of for, it is expected that the LEGP collimator would be suitable for SPECT imaging with $^{99m}Tc$.

• Nuclear Engineering and Technology
• /
• 제56권2호
• /
• pp.715-727
• /
• 2024

During fast neutron imaging, besides the dark current noise and readout noise of the CCD camera, the main noise in fast neutron imaging comes from high-energy gamma rays generated by neutron nuclear reactions in and around the experimental setup. These high-energy gamma rays result in the presence of high-density gamma white spots (GWS) in the fast neutron image. Due to the microscopic quantum characteristics of the neutron beam itself and environmental scattering effects, fast neutron images typically exhibit a mixture of Gaussian noise. Existing denoising methods in neutron images are difficult to handle when dealing with a mixture of GWS and Gaussian noise. Herein we put forward a deep learning approach based on the Swin Transformer UNet (SUNet) model to remove high-density GWS-Gaussian mixture noise from fast neutron images. The improved denoising model utilizes a customized loss function for training, which combines perceptual loss and mean squared error loss to avoid grid-like artifacts caused by using a single perceptual loss. To address the high cost of acquiring real fast neutron images, this study introduces Monte Carlo method to simulate noise data with GWS characteristics by computing the interaction between gamma rays and sensors based on the principle of GWS generation. Ultimately, the experimental scenarios involving simulated neutron noise images and real fast neutron images demonstrate that the proposed method not only improves the quality and signal-to-noise ratio of fast neutron images but also preserves the details of the original images during denoising.

• 한국원자력학회:학술대회논문집
• /
• 한국원자력학회 2001년도 춘계학술발표회요약집
• /
• pp.445.2-445
• /
• 2001

• 대한의용생체공학회:의공학회지
• /
• 제20권6호
• /
• pp.515-521
• /
• 1999

감마카메라에서 섬광체는 감마선을 검출하여 카메라의 영상 특성을 결정하는 주요한 센서역할을 한다. 이 연구에서는 감마카메라 제작시에 고려되어야 하는 섬광체의 옆표면처리가 감마카메라영상에 미치는 영향에 대하여 고찰하였다. 섬광체는 크기가 20mm (직경 $\times$10mm(두께)인 NaI(TI) 와 CsI(TI)를 설정하여 옆표면처리를 반사체와 흡수체로 하였다 . 선정한 4개의 섬광체에서 감마선에 의해 발생한 섬광이 광전자증배관의 광음극에 도달할 때 까지의 광학적 특성을 몬테카를로(Monte Carlo) 시뮬레이션 방법을 이용하여 고찰하였다. 또한 이 네 개의 섬광체를 위치민감형 광전자증배관에 광학적으로 결합하여 Tc-99m 140 keV 에 대한 민감도와 플러드 영상, 에너지 분해능 그리고 위치분해능을 측정하였다. 시뮬레이션 결과, NAI(TI)-반사체가 가장 우수한 민감도를 보인 것으로 계산되었으며, 감마카메라를 이용하여 획득한 플러드영상에서 민감도는 NAI(TI)-반사체 2920cps/$\mu$Ci, NaI(TI)-흡수체2322 cps/$\mu$Ci, CsI(TI) 반사체 1754 cps/$\mu$Ci, CsI(TI)/흡수체 1401 cps/$\mu$Ci로 축정되었다. 내인성 위치분해능은 NaI(TI)-반사체 5.17mm, , NaI(TI)-흡수체 4.54mm, CsI(TI)-반사체 6.99m, CsI(TI)-흡수체 6.31 mm FWHM의 결과를 나타냈다. Tc -99m 140 keV에 대한 에너지분해능은 NaI(TI)-반사체 12.5%, NAI(TI) -흡수체 23.5%, CSI(TI)-반사체 20.5%, CsI(TI) -흡수체 33.3% FWHM으로 측정되었다. 이 연구에서는 감마카메라에서 사용되는 섬광체의 옆표면처리가 카메라의 주요특성에 직접적인 영향을 미친다는 것을 시뮬레이션과 실체 측정방법으로 고찰할 수 있었으며, 두 가지 방법이 일치된 결과를 보여주었다. 결론적으로 섬광체와 광전자증배관 그리고 Tc-99m 선원을 이용하여 영상획득을 목적으로 하는 감마카메라 제작에서는 NAaI(TI) 섬광체가 CSI(TI) 보다 적합하며, 해상력을 고려할 경우에는 섬광체 옆표면을 흡수체로 민감도를 고려할 경우에는 반사체로 선택하여 처리해야 함을 확인하였다.

• Nuclear Engineering and Technology
• /
• 제48권3호
• /
• pp.597-607
• /
• 2016

Personalized medicine is tailored medical treatment that targets the individual characteristics of each patient. Theragnosis, combining diagnosis and therapy, plays an important role in selecting appropriate patients. Noninvasive in vivo imaging can trace small molecules, antibodies, peptides, nanoparticles, and cells in the body. Recently, imaging methods have been able to reveal molecular events in cells and tissues. Molecular imaging is useful not only for clinical studies but also for developing new drugs and new treatment modalities. Preclinical and early clinical molecular imaging shows biodistribution, pharmacokinetics, mechanisms of action, and efficacy. When therapeutic materials are labeled using radioisotopes, nuclear imaging with positron emission tomography or gamma camera can be used to treat diseases and monitor therapy simultaneously. Such nuclear medicine technology is defined as radiation theragnosis. We review the current development of drugs and technology for radiation theragnosis using peptides, albumin, nanoparticles, and cells.