• Journal of Biomedical Engineering Research
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• v.44 no.3
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• pp.176-181
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• 2023

During cancer treatment, the patient's response to drugs appears differently at the cellular level. In this paper, an image-based cell phenotypic feature quantification and key feature selection method are presented to predict the response of patient-derived cancer cells to a specific drug. In order to analyze the viability characteristics of cancer cells, high-definition microscope images in which cell nuclei are fluorescently stained are used, and individual-level cell analysis is performed. To this end, first, image stitching is performed for analysis of the same environment in units of the well plates, and uneven brightness due to the effects of illumination is adjusted based on the histogram. In order to automatically segment only the cell nucleus region, which is the region of interest, from the improved image, a superpixel-based segmentation technique is applied using the fluorescence expression level and morphological information. After extracting 242 types of features from the image through the segmented cell region information, only the features related to cell viability are selected through the ReliefF algorithm. The proposed method can be applied to cell image-based phenotypic screening to determine a patient's response to a drug.

• Korean Journal of Remote Sensing
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• v.38 no.6_1
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• pp.1057-1068
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• 2022

This paper compares the combination performance of feature point-based matching algorithms as a study to confirm the matching possibility between image taken by a user and a virtual texture image with the goal of developing mobile-based real-time image positioning technology. The feature based matching algorithm includes process of extracting features, calculating descriptors, matching features from both images, and finally eliminating mismatched features. At this time, for matching algorithm combination, we combined the process of extracting features and the process of calculating descriptors in the same or different matching algorithm respectively. V-World 3D desktop was used for the virtual indoor texture image. Currently, V-World 3D desktop is reinforced with details such as vertical and horizontal protrusions and dents. In addition, levels with real image textures. Using this, we constructed dataset with virtual indoor texture data as a reference image, and real image shooting at the same location as a target image. After constructing dataset, matching success rate and matching processing time were measured, and based on this, matching algorithm combination was determined for matching real image with virtual image. In this study, based on the characteristics of each matching technique, the matching algorithm was combined and applied to the constructed dataset to confirm the applicability, and performance comparison was also performed when the rotation was additionally considered. As a result of study, it was confirmed that the combination of Scale Invariant Feature Transform (SIFT)'s feature and descriptor detection had the highest matching success rate, but matching processing time was longest. And in the case of Features from Accelerated Segment Test (FAST)'s feature detector and Oriented FAST and Rotated BRIEF (ORB)'s descriptor calculation, the matching success rate was similar to that of SIFT-SIFT combination, while matching processing time was short. Furthermore, in case of FAST-ORB, it was confirmed that the matching performance was superior even when 10° rotation was applied to the dataset. Therefore, it was confirmed that the matching algorithm of FAST-ORB combination could be suitable for matching between virtual texture image and real image.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.12
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• pp.6009-6027
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• 2019

Support vector machine (SVM) classifiers have been widely used for object detection. These methods usually locate the object by finding the region with maximal score in an image. With bag-of-features representation, the SVM score of an image region can be written as the sum of its inside feature-weights. As a result, the searching process can be executed efficiently by using strategies such as branch-and-bound. However, the feature-weight derived by optimizing region classification cannot really reveal the category knowledge of a feature-point, which could cause bad localization. In this paper, we represent a region in an image by a collection of local feature-points and determine the object by the region with the maximum posterior probability of belonging to the object class. Based on the Bayes' theorem and Naive-Bayes assumptions, the posterior probability is reformulated as the sum of feature-scores. The feature-score is manifested in the form of the logarithm of a probability ratio. Instead of estimating the numerator and denominator probabilities separately, we readily employ the density ratio estimation techniques directly, and overcome the above limitation. Experiments on a car dataset and PASCAL VOC 2007 dataset validated the effectiveness of our method compared to the baselines. In addition, the performance can be further improved by taking advantage of the recently developed deep convolutional neural network features.

• Journal of Multimedia Information System
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• v.7 no.1
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• pp.1-10
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• 2020

The image analysis is an important and predominant task for classifying the different parts of the image. The analysis of complex image analysis like histopathological define a crucial factor in oncology due to its ability to help pathologists for interpretation of images and therefore various feature extraction techniques have been evolved from time to time for such analysis. Although deep reinforcement learning is a new and emerging technique but very less effort has been made to compare the deep learning and deep reinforcement learning for image analysis. The paper highlights how both techniques differ in feature extraction from complex images and discusses the potential pros and cons. The use of Convolution Neural Network (CNN) in image segmentation, detection and diagnosis of tumour, feature extraction is important but there are several challenges that need to be overcome before Deep Learning can be applied to digital pathology. The one being is the availability of sufficient training examples for medical image datasets, feature extraction from whole area of the image, ground truth localized annotations, adversarial effects of input representations and extremely large size of the digital pathological slides (in gigabytes).Even though formulating Histopathological Image Analysis (HIA) as Multi Instance Learning (MIL) problem is a remarkable step where histopathological image is divided into high resolution patches to make predictions for the patch and then combining them for overall slide predictions but it suffers from loss of contextual and spatial information. In such cases the deep reinforcement learning techniques can be used to learn feature from the limited data without losing contextual and spatial information.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.42 no.4 s.304
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• pp.119-126
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• 2005

We propose a new content-based image retrieval using a representative color histogram and directional pattern histogram that is adaptive to the classification characteristics of the image blocks. In the proposed method the color and pattern feature vectors are extracted according to the characteristics o: the block classification after dividing the image into blocks with a fixed size. First, the divided blocks are classified as either luminance or color blocks depending on the saturation of the block. Thereafter, the color feature vectors are extracted by calculating histograms of the block average luminance co-occurrence for the luminance block and the block average colors for the color blocks. In addition, block directional pattern feature vectors are extracted by calculating histograms after performing the directional gradient classification of the luminance. Experimental results show that the proposed method can outperform the conventional methods as regards the precision and the size of the feature vector dimension.

• Journal of information and communication convergence engineering
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• v.16 no.3
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• pp.160-165
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• 2018

This paper designed and developed the image processing system of integrating feature extraction and matching by using convolutional neural network (CNN), rather than relying on the simple method of processing feature extraction and matching separately in the image processing of conventional image recognition system. To implement it, the proposed system enables CNN to operate and analyze the performance of conventional image processing system. This system extracts the features of an image using CNN and then learns them by the neural network. The proposed system showed 84% accuracy of recognition. The proposed system is a model of recognizing learned images by deep learning. Therefore, it can run in batch and work easily under any platform (including embedded platform) that can read all kinds of files anytime. Also, it does not require the implementing of feature extraction algorithm and matching algorithm therefore it can save time and it is efficient. As a result, it can be widely used as an image recognition program.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.8 no.1
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• pp.127-135
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• 2009

This paper presents a new technique for corner shape based object retrieval from a database. The proposed feature matrix consists of values obtained through a neighborhood operation of detected corners. This results in a significant small size feature matrix compared to the algorithms using color features and thus is computationally very efficient. The corners have been extracted by finding the intersections of the detected lines found using Hough transform. As the affine transformations preserve the co-linearity of points on a line and their intersection properties, the resulting corner features for image retrieval are robust to affine transformations. Furthermore, the corner features are invariant to noise. It is considered that the proposed algorithm will produce good results in combination with other algorithms in a way of incremental verification for similarity.

• Journal of Computing Science and Engineering
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• v.8 no.2
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• pp.65-77
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• 2014

To address the problem of multi-target retrieval (MTR) of remote sensing images, this study proposes a new object-level feature representation model. The model provides an enhanced application image representation that improves the efficiency of MTR. Generating the model in our scheme includes processes, such as object-oriented image segmentation, feature parameter calculation, and symbolic image database construction. The proposed model uses the spatial representation method of the extended nine-direction lower-triangular (9DLT) matrix to combine spatial relationships among objects, and organizes the image features according to MPEG-7 standards. A similarity metric method is proposed that improves the precision of similarity retrieval. Our method provides a trade-off strategy that supports flexible matching on the target features, or the spatial relationship between the query target and the image database. We implement this retrieval framework on a dataset of remote sensing images. Experimental results show that the proposed model achieves competitive and high-retrieval precision.

• Journal of The Institute of Information and Telecommunication Facilities Engineering
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• v.9 no.2
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• pp.73-79
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• 2010

The most popular technique for image retrieval in a heterogeneous collection of color images is the comparison of images based on their color histogram. The color histogram describes the distribution of colors in the color space of a color image. In the most image retrieval systems, the color histogram is used to compute similarities between the query image and all the images in a database. But, small changes in the resolution, scaling, and illumination may cause important modifications of the color histogram, and so two color images may be considered to be very different from each other even though they have completely related semantics. A new method of color feature representation based on the 3-dimensional RGB color map is proposed to improve the defects of the color histogram. The proposed method is based on the three 2-dimensional projection map evaluated by projecting the RGB color space on the RG, GB, and BR surfaces. The experimental results reveal that the proposed is less sensitive to small changes in the scene and that achieve higher retrieval performances than the traditional color histogram.

• Journal of information and communication convergence engineering
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• v.2 no.2
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• pp.123-127
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• 2004

The most popular technique for image retrieval in a heterogeneous collection of color images is the comparison of images based on their color histogram. The color histogram describes the distribution of colors in the color space of a color image. In the most image retrieval systems, the color histogram is used to compute similarities between the query image and all the images in a database. But, small changes in the resolution, scaling, and illumination may cause important modifications of the color histogram, and so two color images may be considered to be very different from each other even though they have completely related semantics. A new method of color feature representation based on the 3-dimensional RGB color map is proposed to improve the defects of the color histogram. The proposed method is based on the three 2-dimensional projection map evaluated by projecting the RGB color space on the RG, GB, and BR surfaces. The experimental results reveal that the proposed is less sensitive to small changes in the scene and that achieve higher retrieval performances than the traditional color histogram.