• International Journal of Computer Science & Network Security
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• v.22 no.6
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• pp.246-250
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• 2022

The article analyzes the regulations of current criminal law and current issues, combating drug crime on the Internet, as well as measures to combat drug crime in the field of modern information technology. In connection with the growth of crimes in the field of drug trafficking committed with the use of information and telecommunications technologies, the urgent task of the state is to find effective ways to reduce drug crime. The article considers criminologically significant aspects of the mechanism of illicit drug trafficking, which is carried out with the use of information and telecommunication technologies and means of remote communication.

• Research in Community and Public Health Nursing
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• v.18 no.1
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• pp.136-145
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• 2007

Purpose: This study was attempted to illuminate danger signals through an extensive analysis of factors influencing adolescents' illicit drug use. On this basis, it built predictive factors of adolescents' illicit drug use. Method: A questionnaire was distributed to 1,238 subjects living in Seoul, and of them 1,082 answers were analyzed using the SAS 8.2 program. Also logistic regression analysis was conducted based on the stepwise selection method for constructing the predictive factors. Results: The findings of this study are as follows. Individual-related factors were psycho-somatic symptoms, self-esteem, fortune delinquent experience, and sexual-violence delinquent experience. Home-related factors were insincerity, threatening and the assessment of the parent (rearer)-adolescent communication type. Society-related factors were affection of friends and friends' attitude toward delinquency. Conclusion: These findings of this study suggest that a broad intervention program should be provided to nurture wholesome youth culture related to illicit drug use. It is also recommended that a variety of individual, home and society-related programs should be developed for drug users.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.705-714
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• 2012

Objectives: This study assessed the associations between socio-demographic, health and wellbeing variables (independent variables) and daily smoking, attempts to quit smoking, and agreement with smoking ban (dependent variables). Methods: Data from 3,706 undergraduate students were collected from seven universities in England, Wales, and Northern Ireland using a standardised questionnaire. Results: About 15.8% of the whole sample reported daily smoking, while 12% were occasional smokers. Smoking was significantly more prevalent among males, but the difference was due to a higher rate of occasional smokers. About every second smoker (55%) had attempted to quit smoking. Almost 45% of the whole sample agreed or strongly agreed with implementing a total smoking ban on campus. Daily smoking was more likely among students with not sufficient income, students whose fathers had at least a bachelor degree; and, students who reported binge drinking. Conversely, daily smoking was less likely among students who rated their health as very good/ excellent, those who ate ${\geq}5$ portions of fruit or vegetables, and those who had never taken illicit drugs. Previous attempt/s to quit smoking were more likely among students who have never taken illicit drugs and those who agreed with a total smoking ban; and less likely among those with not sufficient income. Daily smokers were less likely to report quit attempts as compared to occasional smokers. An agreement with smoking ban was more likely among students who rated their health as very good/excellent, those who ate ${\geq}5$ portions of fruit or vegetables daily, and those who had never taken illicit drugs, but less likely among daily smokers. Conclusion: Favourable health practices and positive attitudes towards smoking ban were associated with each other. Interventions would need to comprise multi-component programmes that do not solely focus on smoking prevention/cessation, but also on other health promoting practices as well.

• Journal of Preventive Medicine and Public Health
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• v.51 no.1
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• pp.23-32
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• 2018

Objectives: To identify the associations of characteristics of the neighborhood environment with substance abuse among clients receiving treatment for drug abuse in Thailand. Methods: A cross-sectional study was conducted of 1128 drug addicts from 28 neighborhoods who were receiving treatment at all 7 compulsory drug detention centers in Thailand. A trained interviewer conducted structured interviews with the subjects about substance use and the perceived neighborhood environment in their community. A multilevel logistic regression model was applied to estimate the effects of the neighborhood environment on substance use. Results: The majority of participants, 53.8% only used methamphetamine pills, 31.3% used other illicit drugs as well as methamphetamine pills, and 14.9% used an illicit drug other than methamphetamine. Three neighborhood characteristics were associated with substance use. A 1-unit increase in the perceived neighborhood cohesion score was associated with a 15% reduction in methamphetamine pill use and an 11% reduction of the use of both methamphetamine pills and another illicit drug. Conversely, a 1-unit increase in perceived neighborhood crime predicted 19 and 14% increases in the use of methamphetamine pills and the use of both methamphetamine pills and another illicit drug, respectively. In addition, a 1-unit increase in the scores for stigma surrounding addiction corresponded to a 25% increase of the use of methamphetamine pills and a 12% increase in the use of both methamphetamine pills and another illicit drug. Conclusions: Substance use among drug addicts was influenced by characteristics of the neighborhood environment. Therefore, prevention and intervention strategies should be designed based on a consideration of the impact of neighborhood context on substance use behaviors.

• Nuclear Medicine and Molecular Imaging
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• v.40 no.1
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• pp.1-8
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• 2006

Addiction to illicit drugs is one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the pharmacodynamics and pharmacokinetics of the abused drugs, and demonstrate that addiction is a disease of the brain. Continuous researches better illustrate the neurochemical alterations in brain function, and attempt to discover the links to consequent behavioral changes. Newer hypotheses and theories follow the numerous results, and more rational methods of approaching therapy are being developed. Substance abuse is on the rise in Korea, and social interest in the matter as well. On the other hand, diagnosis and treatment of drug addiction is still very difficult, because how the abused substance acts in the brain, or how it leads to behavioral problems is not widely known. Therefore, understanding the mechanism of drug addiction can improve the process of diagnosing addict patients, planning therapy, and predicting the prognosis. Neuroimaging approaches by nuclear medicine methods are expected to objectively judge behavioral and neurochemical changes, and response to treatment. In audition, as genes associated with addictive behavior are discovered, functional nuclear medicine images will aid in the assessment of individuals. Reviewing published literature on neuroimaging regarding nuclear medicine is expected to be of assistance to the management of drug addict patients. What's more, means of applying nuclear medicine to the care of drug addict patients should be investigated further.

• Korean Journal of Child Studies
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• v.26 no.2
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• pp.91-106
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• 2005

The subjects for this study consisted of 301 Korean-American students in grades 6 to 12. Findings of this study showed that most of the risk factors in all domains demonstrated a strong relationship to the use of alcohol, tobacco, and other illicit drugs. In the community domain the most common risk factor was "laws favorable toward drug use"(60.2%); this risk factor increased the odds of substance use by approximately 3 times. The protective factor, "opportunity for positive involvement" in school domain reported by 82% of the sample decreased the probability of substance use by 3 times. The percentage of students "resilient" on all protective factors in the family domain was much lower than that of protective factors in other domains. The strongest predictors of substance use were shown in the peer-individual domain.

• Journal of The Korean Society of Clinical Toxicology
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• v.18 no.1
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• pp.47-50
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• 2020

A 21-year-old female patient complaining of hemiparesis was diagnosed with right middle cerebral artery infarction. No risk factor was found, despite an extensive young-age stroke work-up, except her history of marijuana use. The patient had smoked marijuana for treating depression for more than five years. Magnetic resonance angiography showed multifocal intra- and extracranial stenoses, suggesting cannabinoid-induced vasculopathy. Since the use of illicit drugs has increased nationwide, physicians should consider it as a possible cause of a stroke due to an unknown etiology.

• The Journal of the Korea Contents Association
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• v.22 no.6
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• pp.580-595
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• 2022

This study looked at the relationship between lifestyle choices and various substance addictions in young adults by applying the Relapse Prevention model of addiction. The data was obtained from a cross-sectional questionnaire (Depression and Anxiety Assessment Test) of 926 young adults aged 18~24 from 24 countries. Of these, 17.6% reported that they had a serious substance addiction, with alcohol addiction being the highest (11.2%), followed by nicotine (10.3%) and illicit drug (8.7%) usage. Results of chi-square test and logistic regression analysis revealed a significant association between various lifestyle factors (exercise patterns, intake of dietary nutrients like tryptophan, folic acid, omega-3 fatty acids and micronutrients, spiritual habits such as Bible reading and prayer) and addiction to various substances (illicit drugs, alcohol and nicotine). Depression was also found to be a significant factor influencing substance addiction. Interestingly, the risk of alcohol abuse was the highest at 9.870 (95% CI: 4.525-21.525) times among those who didn't have the habit of daily Bible reading. The highest risk of nicotine and illicit drug addiction was among those who consumed 'less than 1 serving' of dietary micronutrients per day compared to those who consumed '5 or more servings', with odds ratios of 9.606(95% CI: 2.726-30.111) and 8.642(95% CI: 2.022-37.378), respectively. These findings suggest that holistic lifestyle interventions may help prevent and reduce substance addiction in young adults.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.7
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• pp.1062-1071
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• 2018

The misuse of anabolic hormones or illegal drugs is a ubiquitous problem in animal husbandry and in food safety. The ban on growth promotants in food producing animals in the European Union is well controlled. However, application regimens that are difficult to detect persist, including newly designed anabolic drugs and complex hormone cocktails. Therefore identification of molecular endogenous biomarkers which are based on the physiological response after the illicit treatment has become a focus of detection methods. The analysis of the 'transcriptome' has been shown to have promise to discover the misuse of anabolic drugs, by indirect detection of their pharmacological action in organs or selected tissues. Various studies have measured gene expression changes after illegal drug or hormone application. So-called transcriptomic biomarkers were quantified at the mRNA and/or microRNA level by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) technology or by more modern 'omics' and high throughput technologies including RNA-sequencing (RNA-Seq). With the addition of advanced bioinformatical approaches such as hierarchical clustering analysis or dynamic principal components analysis, a valid 'biomarker signature' can be established to discriminate between treated and untreated individuals. It has been shown in numerous animal and cell culture studies, that identification of treated animals is possible via our transcriptional biomarker approach. The high throughput sequencing approach is also capable of discovering new biomarker candidates and, in combination with quantitative RT-qPCR, validation and confirmation of biomarkers has been possible. These results from animal production and food safety studies demonstrate that analysis of the transcriptome has high potential as a new screening method using transcriptional 'biomarker signatures' based on the physiological response triggered by illegal substances.

• YAKHAK HOEJI
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• v.41 no.6
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• pp.698-703
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• 1997

Recently, l-deprenyl (selegiline), a relative new antiparkinson`s drug, has been marketed in Korea. As its metabolites, l-methamphetamine and l-amphetamine, are the enantiomers of illicit drugs,d-methamphetamine and d-amphetamine, a method for analysis of enantiomers of methamphetamine and amphetamine in rat urine was investigated. The optical isomers of methamphetamine and amphetamine were analyzed with the chiral derivatizing reagent (S)-(-)-N-(trifluoroacetyl)-prolyl chloride (l-TFP), which was used to form the diastereomers of methamphetamine and amphetamine. And all diastereomers (l-TFP -l-AM, lTFP-d-AM, l-TFP-l-MA & l-TFP-d-MA) were well resolved by capillary gas chromatography. After administration of 10mg/kg l-deprenyl to rat, l-methamphetamine and l-amphetamine were detected without autoracemization to the d form in all urine samples collected during 24hrs, and the ratios of l-amphetamine/l-methamphetamine were 1.1~3.3. l-Amphetamine was detected in only 3 out of 8 urine samples collected during 24~48hrs where as no l-methamphetamine was detected in all cases.