• 제목/요약/키워드: IkSan

검색결과 120건 처리시간 0.023초

가미진간식풍탕(加味鎭肝熄風湯)이 손상(損傷)된 배양척수운동신경세포(培養脊髓運動神經細胞)에 미치는 영향(影響) (Effects of Gamijingansikpungtang on Cultured Spinal Motor Neurons)

  • 김성환;심정섭;김강산;강병기;이재익
    • 대한한방내과학회지
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    • 제21권2호
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    • pp.283-290
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    • 2000
  • The purpose of this study is to examine the toxic effects caused by xanthine oxidase/hypoxanthine(XO/HX) and the effects of herbal extracts such as Jingansikpungtang(JST) and Gamijingansikpungtang(GJST) on the treatment of the toxic effects. For this purpose, experiments with the cultured nerve cells from the spinal motor neurons of new born mice were done. The results of these experiments were as follows. XO/HX, a oxygen radical-generating system, decreased the survival rate of the cultured cells on NR assay. MTT assay, the amount of neurofilaments and increased the amount of total proteinand increased the lipid peroxidation and the amount of LDH JST has the efficacy of increasing the amount of neurofilaments and total protein, and decreasing the lipid peroxidation and the amount of LDH, GJST has efficacy of increasing the amount of neurofilaments and total protein, and decreasing lipid peroxidation and the amount of LDH. From the above results, it is concluded that JST and GJST have marked efficacy as a treatment for the damages caused in the XO/HX mediated oxidative stress. And JST and GJST are thought to have certain pharmacologicall effects. Further clinical study of this pharmacological effects of JST and GJST should be complemented.

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전남 농공단지 폐수처리장 방류수의 화학적/생물학적 독성평가 (Toxic Assessment on Effluents of Argo/Industrial Wastewater Treatment Plants in Jeonnam using Chemical and Biological Method)

  • 이문희;최익창;한상국
    • 해양환경안전학회지
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    • 제14권4호
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    • pp.267-273
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    • 2008
  • 본 연구는 영산강유역 농공폐수처리장 방류수중의 유기오염물질 분포를 관찰하였다. 시료채취 지점은 영산강 유역에 존재하는 4지점의 농공단지 폐수처리장을 선정하였다. 본 연구에서 GC-Ion trap MS로 300종의 일반적인 화학물질을 ppt수준에서 검출할 수 있는 방법을 이용하여 분석하였다. 농공폐수처리방류수에서 검출된 주요 유기오염물질은 농약류, CH구조의 방향족, CHO구조의 프탈레이트류, 그리고 CHO(N) 구조의 아로메틱 아민류였다. 또한 diethylphthalate를 포함한 17종의 내분비계장애물질이 검출되었다. XTT assay를 이용한 세포독성 결과는 TV로 나타냈으며, 그들의 세포독성은 A지점에서 27.2, D지점에서 24.4로 가장 높게 나타났다. 한편 화학적 분석 결과와 생물학적 독성도와는 일치하지 않는 것으로 나타났다.

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통계적 품질관리도를 활용한 차별적 경찰대응전략의 평가 (Evaluating the Quality of the Differential Police Response Strategy: Applications of Statistical Quality Control Charts)

  • 이명우;김지훈;박한호
    • 한국콘텐츠학회논문지
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    • 제16권6호
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    • pp.529-536
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    • 2016
  • 본 연구의 목적은 차별적 경찰대응전략의 품질을 평가하는 것이다. 새로운 경찰대응시스템이 도입된 지 약 3년이 지났지만, 이를 실증적으로 평가한 연구는 미비한 실정이다. 2가지 종류의 통계적 품질관리 기법을 활용하여, 2012년 한해동안 익산경찰서에 신고된 약 3,000건의 경찰데이터를 분석하였다. "Xbar-R 관리도"의 분석결과, 경찰은 긴급출동신고전화 (Code 1)에 지속적으로 신속히(3분 이내) 대응하지 못하는 것으로 나타났다. 더불어 "P 관리도"의 분석결과, 경찰은 비긴급출동신고전화 (Code 2)에 5분이내로 대응하지 못한 출동건수의 월별 상이성이 큰 것으로 나타났다. 본 연구에서 알 수 있듯이 경찰이 추구하는 "신속한" 수준의 대응전략에 있어 코드별 목표대응시간에 대하여 재검토 할 필요성이 제기된다.

기계적인 합금화에 의한 Mg-18wt.%Ni 수소저장합금의 개발 (Development of Mg-18wt.%Ni-Hydrogen-Storage Alloy by Mechanical Alloying)

  • 송명엽;안동수;권익현;안효준
    • 한국재료학회지
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    • 제10권1호
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    • pp.15-20
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    • 2000
  • 기계적으로 합금처리한 Mg-18wt.%Ni 혼합물의 수소저장특성이 조사되었다. 1h, 3h, 그리고 6h 동안 기계적으로 합금처리한 혼합물들 중에서 6h동안 기계적으로 합금처리한 혼합물(MA 6h sample)이 가장 좋은 활성화, 수소화물 형성.분해 특성을 보인다. 수소화물 형성.분해 cycling을 시킴에 따라 $Mg_2$Ni상이 형성된다. MA 6h sample은 비교적 쉽게 활성화되며, 순수한 Mg나 Mg-10wt.%Ni 합금보다 수소화물 형성속도가 높으나, $Mg_2$Ni 합금보다는 수소화물 형성속도가 약간 낮다. MA 6h sample은 $Mg_2$Ni 합금에 비해 낮은 수소화물 분해속도를 보이지만, 순수한 Mg나 Mg-25wt.%Ni 합금보다는 높은 수소화물 분해속도를 보인다. MA 6h sample은 순수한 Mg나 다른 합금들보다 큰 수소저장용량을 가지고 있다.

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견비통(肩臂痛) 치료(治療) 혈위(穴位)에 있어 Kim Sham Acupuncture를 이용한 단일 맹검에 관한 임상실험(臨床實驗) (The Study of the Kim Sham Acupuncture for Single Blind about the Acupuncture Points used for Treatment of the Shoulder Pain.)

  • 이성용;임정아;나원민;이충식;김대중;김성철
    • Journal of Acupuncture Research
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    • 제23권6호
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    • pp.133-143
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    • 2006
  • Objectives : To Investigate Severity Measurement and the Correlation between Acupoints on the Face and the Upper limb in Bell's Palsy Patients by Using of DITI. Methods : We recreated the persons in the Wonkwang oriental hospital, KwangJu and the public health center, Hwasoon from April 2005 to October 2005. the 60 persons randomized allocated were not showed the acupuncture and treated in the acupuncture points used for treatment of the shoulder pain. the 30 persons were treated with real acupuncture and the others were treated with Kiln Sham Acupuncture. Conclusion : This report suggest that we must except Kyon-lyo(TE14), kyon-u(LI15), and hu-gye(SI03) from the shoulder pain study with Kim Sham Acupuncture because the persons significantly distinguished Real acupuncture from Sham acupuncture at the Kyon-lyo(TE14), kyon-u(LI15) and hu-gye(SI03) and so We cannot blind a person.

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근린공원 시설유형에 따른 이용실태 및 만족도에 관한 연구 (A Study on Status of Use of Community Park and Level of Satisfaction Based on Types of Its Facilities)

  • 박율진;김화옥
    • 한국환경과학회지
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    • 제19권4호
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    • pp.427-436
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    • 2010
  • In this study this author made research and analysis on physical status and characteristics of community parks in Ik-san provinces and also depending on its potential resources such parks were classified into constructed parks and unconstructed parks and status of use of such parks and level of satisfaction were studied. Through this paper this author strived to provide basic data required for forming green track of land for the parks. Required time for visiting community parks either constructed or unconstructed type was within 40 minutes or less. However constructed parks appeared to be more convenient for access in comparison with natural unconstructed parks. Mostly they were used by residents in neighboring community and also residents in the area around it were found as using it frequently. At the time of using community parks either constructed or unconstructed types means of access were mostly by walking or by riding bicycles. Thus considering large number of users of such parks are from neighboring community it appeared that parks with its simplicity and convenience in terms of distance and with rich nature were preferred by users rather than large scale parks at distance. In terms of time frame of use and motivation of visit constructed parks were used mainly for exercise and relaxation in the morning at parks and its facilities whereas un constructed parks were mostly used in the afternoon for for walking and chatting and rest under with time to spare at shadows of its trees. Time spent at parks were composed mostly of rest and walking more frequently than exercise and leisure activity thus it was different from motivation for visiting parks. As for evaluation of use of parks natural elements, unique environment, trees and lawns featured highly in unconstructed parks in comparison with constructed parks. Thus it seemed visitors are more conscious of forest and landscape in a form of unchanged nature. Thus for community parks first consideration should be heightening accessibility in view of primary concern for convenience by users rather than facilities or environmental conditions.

수송모형이론에 의한 토공 운반 최적화 모델 및 프로그램 개발 (Developing an Optimization Model and Program for Planning the Earthwork Based Upon Transportation Theory)

  • 이승학;손재호;편재호;이승현
    • 한국건설관리학회논문집
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    • 제17권1호
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    • pp.101-109
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    • 2016
  • 도로공사 토공사 작업현장에서 수행되는 운반계획의 주요 목적은 절토량과 성토량 간의 균형을 맞추는 것과 운반비용, 운반거리를 최소화 하는 것이다. 토공사의 합리적인 운반계획은 공사비 및 공사기간에 직접적인 영향을 미치나, 기존의 토공사 운반계획은 현장관리자의 경험적 지식을 기반으로 토공 운반계획을 수립하는 실정이다. 이에 본 연구에서는 도로공사 토공사 작업현장의 토공물량 운반계획의 효율성 향상을 위해 활용할 수 있는 최적화 모델 개발 하였으며, 사례구간을 통해 본 연구를 적용시킨 결과 공사기간은 약 19%, 공사비는 약 11% 감소시킨 것으로 확인되었다.

Decreased Triglyceride and Cholesterol Levels in Serum, Liver and Breast Muscle in Broiler by the Supplementation of Dietary Codonopsis lanceolata Root

  • Shim, K.S.;Park, G.H.;Choi, C.J.;Na, C.S.
    • Asian-Australasian Journal of Animal Sciences
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    • 제17권4호
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    • pp.511-513
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    • 2004
  • Effects of the dietary supplementation of Codonopsis lanceolata root on triglyceride and cholesterol levels in the serum, liver, breast muscle and bile in male Cobb$\times$Cobb chicks were investigated. The chicks (15-42 days old) were fed diets supplemented with 0, 0.25 and 0.5% Codonopsis lanceolata root. No differences were observed in body weight, feed conversion ratio, gall bladder weight or abdominal fat deposition among the control group and the two treatment groups. Liver weights were higher in chicks fed a 0.5% Codonopsis lanceolata diet than in those fed the control diet (p<0.05). However, serum levels of both glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) were not different among the three groups. Broiler chicks fed either 0.25% or 0.5% dietary Codonopsis lanceolata root showed decreased serum levels of triglyceride, total cholesterol and low density lipoprotein cholesterol compared to the control group (p<0.05). Supplementation with either 0.25% or 0.5% dietary Codonopsis lanceolata root decreased the triglyceride and total cholesterol levels in liver and breast muscle compared to the control group (p<0.05). Biliary cholesterol increased by 15% in chicks fed 0.5% dietary Codonopsis lanceolata root, suggesting that the biliary excretion of cholesterol had been elevated by dietary Codonopsis lanceolata root (p<0.05). In conclusion, these results indicate that dietary Codonopsis lanceolata root can decrease triglyceride and cholesterol levels in the serum, liver and breast muscle of broilers.

능동형 엔진 마운트 성능 평가를 위한 6축 시뮬레이터 구축 (Development of 6-DOF Simulator for Active Engine Mounting System)

  • 김정훈;김재산;이한동;박태익
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2011년도 춘계학술대회 논문집
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    • pp.520-525
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    • 2011
  • As worldwide concern stands on global warming and greenhouse gases from internal combustion engine, the interests in technologies for a highly efficient powertrain has been increased. Concurrently the investigation to improve the deteriorated NVH, a by-product of energy efficient powertrain, is conducted seriously. The NVH performance of a new type of active engine mount that offers increased advantages over a passive hydraulic mount is examined using a newly developed 6-DOF simulator. The simulator is in the shape of Hexapod Stewart Platform adopting LEMA, a new type of actuator which is patented and commercialized by ACT Inc,, the world wide leader in the design, development, and manufacture of high performance linear electro-magnetic actuators for active vibration control. The target vibration signals of an aimed vehicle at four engine mounts are measured and simulated by 6-DOF simulator at the laboratory. The resulting NVH performances of the new active mounting system at a vehicle and on a simulator are examined and compared. Even though the active mount performance of lab test demonstrates less effective than the result of a real vehicle test, vibration reduction is identified through the simulator.

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자세조절훈련이 만성 뇌졸중 환자의 균형과 보행 능력에 미치는 영향 (The Effect of Postural Control Training on Balance and Walking Ability in Patients with Chronic Stroke)

  • 방대혁;조혁신
    • 대한물리의학회지
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    • 제12권2호
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    • pp.59-66
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    • 2017
  • PURPOSE: The purpose of this study was to determine the effects of postural control training on balance and walking ability in chronic stroke patients. METHODS: Eighteen chronic stroke patients were allocated equally and randomly to an experimental group (n=9) or a control group (n=9). All participants received 60 minutes of comprehensive rehabilitation treatment, the experimental group additionally received a postural control training for 30 minutes, while the control group additionally performed a treadmill training for 30 minutes. These 30-minute training sessions were held five times per week for three weeks. Balance was assessed using Berg balance scale (BBS) and walking ability (gait speed, cadence, step length, and double limb support) was assessed using the GAITRite system. RESULTS: Improvement on all outcome measures was identified from pre-to-post intervention for both groups (p<.05). Post-intervention, there was a significant between-group difference on measured outcomes (p<.05). The experimental group exhibited greater improvement in the gait speed (p=.01; 95% CI .08-.16), cadence (p=.04; 95% CI .34-4.79), step length (p=.02; 95% CI 1.50-5.17), double limb support period (p=.04; 95% CI -2.18 to -.14), and BBS (p=.01; 95% CI 1.04-6.74) compared to the control group. CONCLUSION: The findings of this study suggest that postural control training may be beneficial for improving balance and walking ability of patients with chronic stroke.