• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.9
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• pp.1996-2002
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• 2013

In this paper, a design method for a compact broadband planar monopole antenna fed by a coplanar waveguide (CPW) is studied. The proposed broadband monopole is optimized for terrestrial digital television (DTV) reception. In order to achieve broadband characteristics, the monopole and ground conductor are gradually tapered. By loading slit pairs on both monopole and ground plane, the proposed antenna is miniaturized. The monopole is fed by a CPW with 75-ohm characteristic impedance on an FR4 substrate and its size is $100mm{\times}200mm$. The optimized monopole antenna for DTV band (470-806 MHz) is fabricated on an FR4 substrate and tested experimentally to verify the results of this study.

• BMB Reports
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• v.30 no.5
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• pp.326-331
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• 1997

To construct a competitive ELISA standard curve for the detection of glucose-6-phosphate debydrogenase (G6PD), we used highly purified native G6PD (nG6PD) as both immobilized and soluble antigens and anti-G6PD serum raised against nG6PD as antibody. The polystyrene cuvettes coated with nG6PD were challenged with a mixture of a limiting amount of anti-G6PD serum and various doses of nG6PD as competitors followed by incubation with alkaline phosphatase-anti-IgG conjugate. The competitive ELISA did not exhibit the typical sigmoidal dose-response curve characteristic of competition immunoassays under the optimal concentrations of antigen and antibody. The soluble nG6PD used as competitor failed to effectively inhibit the binding of antibodies to the immobilized nG6PD. The addition of NADP, a cofactor of G6PD enzyme, to coating buffer used for immobilizing nG6PD to the cuvettes and PBS-Tween-BSA buffer for diluting competitors did not improve the inhibition of antibody binding to immobilized nG6PD by soluble n/G6PD. The addition of BSA to coating buffer did not increase inhibition, either. Surprisingly, when partially active G6PD (paG6PD), obtained by repeated freeze-thawing, was used as competitor, the antibody binding to either immobilized nG6PD or immobilized paG6PD was inhibited 49-58%. We conclude that an effective competitive ELISA system with nG6PD enzyme and anti-G6PD serum for the detection of G6PD may not be established due to the poor inhibition of antibody binding to immobilized nG6PD by soluble nG6PD under the present assay conditions and that the inhibition may be improved by using an inactivated enzyme as competitor regardless of the type of immobilized antigen used. These results imply that the immobilized nG6PD may undergo denaturation upon binding to the polystyrene cuvettes and that our anti-G6PD serum may recognize denatured enzyme better than active enzyme.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.05a
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• pp.61-62
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• 2018

In this paper, we studied a wideband double-sided dipole antenna operating at 3.5 GHz (WiMAX) band. The each printed dipoles are placed on the both sides of the substrate. It can be easily implemented and is suitable for connection with an active circuit. In order to obtain wideband printed dipole characteristics, thick rectangular shaped dipole is adopted. Feeding Circuit for dipole array and balun were designed for impedance matching with a $50{\Omega}$ microstrip feed line. The antenna is designed by simulation for an operation in the frequency range of 3.4~3.7 GHz Simulation results show that the maximum gain in the 3.5 GHz band is 5.5 dBi and the bandwidth with VSWR less than 2 is about 1 GHz.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.46 no.2
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• pp.31-37
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• 2009

This paper presents an efficient frame synchronization strategy with the identification of modulation type for Digital Video Broadcasting-Satellite second generation (DVB-S2). To detect the Start Of Frame (SOF) and identify a modulation mode at low SNR, we propose a new correlator structure and a low complexity Automatic Gain Controller (AGC). The proposed frame synchronization architecture can reduce about 93% multipliers and 89% adders compared with the direct implementation of the Differential - Generalized Post Detection Integration (D-GPDI) algorithm which is very complex and the proposed a low complexity AGC consists of only 5 multipliers and 3 adders. The proposed architecture has been thoroughly verified on the Xilinx Virtex II FPGA board.

• Herbal Formula Science
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• v.21 no.1
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• pp.161-176
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• 2013

Objectives : To clarify the anti-arthritic activity of Ostericum koreanum Maxim. (OS) plus Aralia continentalis Kitagawa (AC) in vivo. Methods : All mice were immunized with bovine type II collagen. After a second collagen immunization, mice were treated with OS plus AC once a day for 7 weeks. Oral administration of OS plus AC (200 or 50 mg/kg) significantly suppressed the progression of CIA, which extend is comparable to that of methotrexate (MTX, 0.3 mg/kg), a positive control. The severity of arthritis within the knee joints was evaluated by histological assessment of cartilage destruction and pannus formation. Results : Administration of OS plus AC significantly suppressed the progression of CIA and inhibited the production of TNF-${\alpha}$ and IL-6 in serum. The erosion of cartilage was dramatically reduced in mouse knees after treatment with OS plus AC. In conclusion, our results demonstrates that OS plus AC significantly suppressed the progression of CIA and that this action was characterized by the decreased production of IL-6, IFN-${\gamma}$ and collagen II specific antibody in serum, CD3+CD69+ T cells, MHC class II+/CD11c+ (in DLN), CD11b+Gr-1+ cells (in PBMC), CD11b +Gr-1+ cells, B220+/CD23+ (in paw joint). Conclusions : The the levels of IFN-${\gamma}$ in the culture supernatant of splenocytes stimulated with CD3/CD28 or collagen were dramatically decreased, while those of IL-4 was increased. In the serum of OS and AC-treated mice, the levels of IgM RA factor were decreased.

• Clinical and Experimental Pediatrics
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• v.60 no.8
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• pp.261-265
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• 2017

Purpose: Studies on cytomegalovirus (CMV) infections in immunocompetent children are lacking, and minimal information is available in the medical literature on hepatic manifestations and complications of CMV. The aims of this study were to evaluate the clinical characteristics, laboratory data, and prognosis of children with CMV hepatitis, and to investigate its prevalence at a single medical center in Korea over a 10-year period. Methods: One hundred thirty-two children diagnosed with CMV infection based on specific markers (anti-CMV IgM, CMV polymerase chain reaction in blood and urine, or CMV culture of urine) were included in the study. Clinical and biochemical characteristics, immunological markers, and outcomes of hepatic CMV infection were determined. Results: The median age of patients (n=132) was 8.5 months (range, 14 days-11.3 years). Peak total bilirubin and alanine aminotransferase levels in serum ranged from 0.11-21.97 mg/dL, and 5-1,517 IU/L, respectively. Alanine aminotransferase remained elevated from 2-48 weeks. Jaundice was the most common clinical feature of hepatic CMV infection during infancy. The hematologic findings revealed anemia, leukocytosis, and monocytosis in CMV-infected patients. All participants recovered without administration of ganciclovir. Conclusion: In children with CMV hepatitis, fever was the most common symptom at presentation, and jaundice was the most common clinical feature of hepatic CMV infection in infants younger than 3 months of age. Hepatic CMV infection in immunocompetent children is often a self-limited illness that does not require antiviral therapy, as most patients in this study had favorable outcomes.

• Parasites, Hosts and Diseases
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• v.51 no.2
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• pp.247-253
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• 2013

Neospora caninum is the etiologic agent of bovine neosporosis, which affects the reproductive performance of cattle worldwide. The transmembrane protein, NcSRS2, and dense-granule protein, NcGRA7, were identified as protective antigens based on their ability to induce significant protective immune responses in murine neosporosis models. In the current study, NcSRS2 and NcGRA7 genes were spliced by overlap-extension PCR in a recombinant adenovirus termed Ad5-NcSRS2-NcGRA 7, expressing the NcSRS2-NcGRA7 gene, and the efficacy was evaluated in mice. The results showed that the titer of the recombinant adenovirus was $10^9TCID_{50}/ml$. Three weeks post-boost immunization (w.p.b.i.), the IgG antibody titer in sera was as high as 1:4,096. IFN-${\gamma}$ and IL-4 levels were significantly different from the control group (P<0.01). This research established a solid foundation for the development of a recombinant adenovirus vaccine against bovine N. caninum.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.24 no.3
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• pp.84-107
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• 2011

Purposes : The purpose of present study is to detect the effects of ointment contained Takrisodok-Eum on the skin barrier's recovery of the Atopic dermatitis. Methods : A total of 44 patients who visited Semyung Oriental Medical Center from April 27th, 2011 to September 20th, 2011 were included in the study. In this study, the patients were treated with Takrisodok-Eum (experimental group) and positive control group. For 8 weeks of gross examination, hematological examination and instrumental asessment were made before and after the study to examine how well the products for experimental group with those for control group in recovering the damaged skin barriers by Atopic dermatitis. Results : 1. In the primary endpoint, SCORAD Index showed a statistically significant decline in experimental group. 2. In the secondary endpoint index of skin hydration, both the experimental group and the control group showed statistical significance. 3. In the secondary endpoint index of TEWL, the experimental group showed greater statistical significance than the control group. 4. In the secondary endpoint index of skin pH, skin pH showed a statistically significant decline in both the control group and the experimental group within the normal range. 5. In the secondary endpoint index of Total IgE, Eosinophil count, IL-10, IL-13, both the experimental group and the control group showed no statistical significance. 6. To evaluate the safety of the products for the human body, hematological examination and hematological biochemical examination, vital sign check were conducted; both control group and experimental group showed no abnormal level. And There were no severe adverse events during this study. Therefore, it is suggested that the safety of the products, if used for certain period, should be safe for the human body. Conclusions : According to the above experiments, it is suggested that Takrisodok-Eum should be effective for the Atopic dermatitis.

• Journal of Soil and Groundwater Environment
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• v.12 no.5
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• pp.98-104
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• 2007

A survey was performed to evaluate the distribution of radon concentrations in groundwater of South Korea. Groundwaters of 615 wells were sampled for this study during the four years from 1999 to 2002. The results showed radon values ranging from 4 pCi/L to 40,010 pCi/L with a mean and a median of 1,862 pCi/L and 920 pCi/L, respectively. The samples were classified into five groups according to the rock types; granite, sedimentary rocks, metamorphic rocks, Ogcheon metamorphic rocks, and Cheju volcanics. Mean radon concentrations were highest (2,595 pCi/L) in granites and lowest (238 pCi/L) in Cheju volcanic rocks. The groundwaters generally showed the highest radon content (2,298 pCi/L) in the weathered and the fractured bedrock complex and the lowest level (672 pCi/L) in the alluvium. The results showed that the radon concentrations in South Korea are low relative to those reported from other countries. But further investigations are suggested to confirm our results.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.46 no.10
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• pp.40-45
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• 2009

In this paper, we introduce a mobile-type tiny sensor device that can classify the activities of daily living based on the state-dependent motion analysis using a 3-axial accelerometer in real-time. The device consists of an accelerometer, GPS module, 32bit micro-controller for sensor data processing and activity classification, and a bluetooth module for wireless data communication. The size of device is 50*47*14(mm) and lasts about 10 hours in operation-mode and 160 hours in stand-by mode. Up to now, the device can recognize three user activities ("Upright", "Running", "Walking") based on the decision tree. This tree is constructed by the pre-learning process to activities of subjects. The accuracy rate of recognizing activities is over 90% for various subjects.