• Title/Summary/Keyword: Identification Index

Search Result 555, Processing Time 0.026 seconds

Collision Risk Assessment by using Hierarchical Clustering Method and Real-time Data (계층 클러스터링과 실시간 데이터를 이용한 충돌위험평가)

  • Vu, Dang-Thai;Jeong, Jae-Yong
    • Journal of the Korean Society of Marine Environment & Safety
    • /
    • v.27 no.4
    • /
    • pp.483-491
    • /
    • 2021
  • The identification of regional collision risks in water areas is significant for the safety of navigation. This paper introduces a new method of collision risk assessment that incorporates a clustering method based on the distance factor - hierarchical clustering - and uses real-time data in case of several surrounding vessels, group methodology and preliminary assessment to classify vessels and evaluate the basis of collision risk evaluation (called HCAAP processing). The vessels are clustered using the hierarchical program to obtain clusters of encounter vessels and are combined with the preliminary assessment to filter relatively safe vessels. Subsequently, the distance at the closest point of approach (DCPA) and time to the closest point of approach (TCPA) between encounter vessels within each cluster are calculated to obtain the relation and comparison with the collision risk index (CRI). The mathematical relationship of CRI for each cluster of encounter vessels with DCPA and TCPA is constructed using a negative exponential function. Operators can easily evaluate the safety of all vessels navigating in the defined area using the calculated CRI. Therefore, this framework can improve the safety and security of vessel traffic transportation and reduce the loss of life and property. To illustrate the effectiveness of the framework proposed, an experimental case study was conducted within the coastal waters of Mokpo, Korea. The results demonstrated that the framework was effective and efficient in detecting and ranking collision risk indexes between encounter vessels within each cluster, which allowed an automatic risk prioritization of encounter vessels for further investigation by operators.

Identification of a conservative site in the African swine fever virus p54 protein and its preliminary application in a serological assay

  • Xu, Lingyu;Cao, Chenfu;Yang, Zhiyi;Jia, Weixin
    • Journal of Veterinary Science
    • /
    • v.23 no.4
    • /
    • pp.55.1-55.12
    • /
    • 2022
  • Background: ASF was first reported in Kenya in 1910 in 1921. In China, ASF spread to 31 provinces including Henan and Jiangsu within six months after it was first reported on August 3, 2018. The epidemic almost affected the whole China, causing direct economic losses of tens of billions of yuan. Cause great loss to our pig industry. As ELISA is cheap and easy to operate, OIE regards it as the preferred serological method for ASF detection. P54 protein has good antigenicity and is an ideal antigen for detection. Objective: To identify a conservative site in the African swine fever virus (ASFV) p54 protein and perform a Cloth-enzyme-linked immunosorbent assay (ELISA) for detecting the ASFV antibody in order to reduce risks posed by using the live virus in diagnostic assays. Method: We used bioinformatics methods to predict the antigen epitope of the ASFV p54 protein in combination with the antigenic index and artificially synthesized the predicted antigen epitope peptides. Using ASFV-positive serum and specific monoclonal antibodies (mAbs), we performed indirect ELISA and blocking ELISA to verify the immunological properties of the predicted epitope polypeptide. Results: The results of our prediction revealed that the possible antigen epitope regions were A23-29, A36-45, A72-94, A114-120, A124-130, and A137-150. The indirect ELISA showed that the peptides A23-29, A36-45, A72-94, A114-120, and A137-150 have good antigenicity. Moreover, the A36-45 polypeptide can react specifically with the mAb secreted by hybridoma cells, and its binding site contains a minimum number of essential amino acids in the sequence 37DIQFINPY44. Conclusions: Our study confirmed a conservative antigenic site in the ASFV p54 protein and its amino acid sequence. A competitive ELISA method for detecting ASFV antibodies was established based on recombinant p54 and matching mAb. Moreover, testing the protein sequence alignment verified that the method can theoretically detect antibodies produced by pigs affected by nearly all ASFVs worldwide.

A Study on the Estimation of Service Level for National Fishing Harbour Breakwater Lighthouse Based on the Traffic Volume (통항량 기반의 국가어항 방파제등대 서비스수준 추정 연구)

  • Moon, Beom-Sik;Song, Chae-uk;Kang, Jeong-Gu;Kim, Tae-Goun
    • Journal of Navigation and Port Research
    • /
    • v.45 no.6
    • /
    • pp.306-313
    • /
    • 2021
  • National fishing harbour is as a refuge for fishing boats and a breakwater lighthouse is installed as a functional facility in consideration of harbour identification and the safety of passing vessels. In this study, the service level of breakwater lighthouse (234 units) was estimated based on the traffic volume of 105 national fishing harbour. For this purpose, the evaluation items were determined, the fishing harbour standard index was calculated (Fs=1), the proximity of fishing harbour was identified and the function (service level) of the breakwater lighthouse was estimated in the following order. However, national fishing harbour differed in size, traffic volume and fishing vessel capacity. Therefore, 105 national fishing harbour were divided into three groups through cluster analysis. The cluster analysis was based on the service level factors of the breakwater lighthouse, such as the number of weeding fishing vessels, tonnage of fishing vessels, the number of incoming and outgoing vessels per year, and fishing vessel capacity. As a result of the estimation, the service level of the breakwater lighthouse (light tower height, visual height, visual range, interval) was 10.50m, 16.50m, 7.00mile, 5.5sec for group 1, and 10.67m, 16.16m, 8.33mile, and 6.0sec for group 2, The three groups are 11.53m, 16.75m, 6.75mile and 5.0sec. The results of this study can be used as useful basic data for improving the service level of traffic vessels when a breakwater lighthouse is built in a fishing harbour in the future.

Association of Korean Medicine Pattern Identifications and Liver Blood Markers with the Severity of Cognitive Impairment in an Elderly Population (경도인지장애와 경도치매 단계에서의 한의 변증 및 간 혈액지표 연관성 탐색 연구)

  • Kahye Kim;Jiyun Cha;Seul Gee Kim;Hyung-Won Kang;Yeoung-Su Lyu;In Chul Jung;Jaeuk U. Ki
    • Journal of Oriental Neuropsychiatry
    • /
    • v.34 no.3
    • /
    • pp.141-150
    • /
    • 2023
  • Objectives: This study aimed to comprehend the characteristics of Korean medicine patterns in relation to varying degrees of cognitive impairment in an elderly population. Methods: The dataset included 127 elderly individuals with cognitive impairment obtained from three Korean medicine hospitals between 2018 and 2021. The participants were categorized into two groups based on Clinical Dementia Rating-Sum of Boxes (CDR-SB) scores: those with questionable impairment (QI) and those with very mild dementia (VMD). A diagnostic framework for Korean medicine patterns encompassing Qi deficiency, Yin deficiency, Phlegm dampness, and Heat-fire was employed. Liver blood markers, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), and the AST/ALT ratio, were also analyzed. Results: The scores of the cognitive assessment tools (MoCA-K, MMSE-DS, and K-IADL) of the QI group significantly differed from those of the VMD group. CDR-SB exhibited a positive correlation with the scores of each pattern of Qi deficiency, Yin deficiency, Phlegm dampness, and Heat-fire, whereas ALT and AST values displayed negative correlations. Binomial logistic analysis, controlling for potential confounders, such as age, education years, body mass index, the presence of chronic disease, and the presence of medication, verified that the VMD group showed higher pattern scores and lower ALT and AST values than the QI group. Conclusions: Increases in pattern scores along with decreased AST and ALT levels might be indicative of more severe cognitive impairment.

The Relationship between Left Ventricular Hypertrophy by Transthoracic Echocardiography and Dampness-Phlegm Diagnosis in Cerebral Infarction Patients (경흉부 심초음파를 이용한 뇌경색 환자의 좌심실 비대와 습담변증(濕痰辨證)의 관련성 연구)

  • Kwak, Seung-hyuk;Woo, Su-kyung;Lee, Eun-chan;Hyun, Sang-ho;Park, Joo-young;Jung, Woo-sang;Moon, Sang-kwan;Cho, Ki-ho;Park, Sung-uk;Ko, Chang-nam
    • The Journal of the Society of Stroke on Korean Medicine
    • /
    • v.13 no.1
    • /
    • pp.13-23
    • /
    • 2012
  • Object : The aim of this study was to assess the relationship between left ventricular hypertrophy and Dampness-Phlegm diagnosis in cerebral infarction patients. Methods : Among 227 of the total recruited patients, 59 patients were diagnosed as left ventricular hypertrophy. We assessed their general characteristics, risk factors, lab findings and Korean medical diagnosis. We compared the assessed variables between left ventricular hypertrophy group and non left ventricular group. We analyzed the relationship between left ventricular hypertrophy and risk factors. And we also analyzed the relationship between left ventricular hypertrophy and dampness-phlegm diagnosis. Results : 1. The rate of left ventricular hypertrophy in female patients was larger than the rate of male patients. 2. There were more patients finally diagnosed hypertension in left ventricular hypertrophy group. 3. According to the analysis about the rate of Dampness-phlegm related Index for Pattern Identification by left ventricular hypertrophy, Sallow complexion and obesity were significantly higher in the left ventricular hypertrophy than in the non left ventricular hypertrophy group. 4. In multivariate analysis, Dampness-phlegm group showed close relationship with left ventricular hypertrophy. Conclusions : According to the analysis, significance between dampness-phlegm diagnosis diagnosed group and left ventricular hypertrophy were clarified. These results can be utilized in the future as a basic material to be used for diagnosis and management of dampness-phlegm diagnosis on cardiovascular diseases.

  • PDF

Motivation for Alcohol Use, Problem Drinking, Family Alcohol Use and Dating Violence among College Students (음주 동기, 문제음주 및 음주 가족력과 대학생의 데이트 폭력)

  • Kyung Hyun Suh
    • Korean Journal of Culture and Social Issue
    • /
    • v.9 no.2
    • /
    • pp.61-78
    • /
    • 2003
  • The researcher examined the relationship between dating violence and drinking behaviors. Study participants included 440 Korean College students(184 males and 256 females) currently involved in heterosexual dating relationships. Participants' ages ranged from 17 to 30(M=20.08, SD=1.89). Questionnaires and psychological tests used included: Straus' Conflict Tactics Scale, Alcohol Use Disorder Identification Test(AUDIT), Cooper's Revised Drinking Motives Questionnaire(DMQ), and Index of Family Alcohol Use. Research designs were 2(gender) × 2(experience of inflicting dating violence), i.e. 2-way MANOVAs. Results suggest students who drink one or more times a week are more likely to commit acts of violence toward their dating partners than students drinking less often. The study revealed males tend to drink with higher social, enhancement, conformity and coping motives than females. The study also showed that students inflicting dating violence drank with higher coping motives than students who did not. Males showed more hazardous, dependent and harmful drinking patterns than females. Also, students who had inflicted dating violence showed a higher degree of these characteristics (hazardous, dependent and harmful drinking patterns) along with a greater family history of alcohol use than participants who had not inflicted dating violence. The findings showed significant 2-way interactions in dependent and harmful drinking patterns. Simple main effect analysis revealed that differences in dependent and harmful drinking patterns in males are more significant than the same differences in females.

  • PDF

Research on the Development of Distance Metrics for the Clustering of Vessel Trajectories in Korean Coastal Waters (국내 연안 해역 선박 항적 군집화를 위한 항적 간 거리 척도 개발 연구)

  • Seungju Lee;Wonhee Lee;Ji Hong Min;Deuk Jae Cho;Hyunwoo Park
    • Journal of Navigation and Port Research
    • /
    • v.47 no.6
    • /
    • pp.367-375
    • /
    • 2023
  • This study developed a new distance metric for vessel trajectories, applicable to marine traffic control services in the Korean coastal waters. The proposed metric is designed through the weighted summation of the traditional Hausdorff distance, which measures the similarity between spatiotemporal data and incorporates the differences in the average Speed Over Ground (SOG) and the variance in Course Over Ground (COG) between two trajectories. To validate the effectiveness of this new metric, a comparative analysis was conducted using the actual Automatic Identification System (AIS) trajectory data, in conjunction with an agglomerative clustering algorithm. Data visualizations were used to confirm that the results of trajectory clustering, with the new metric, reflect geographical distances and the distribution of vessel behavioral characteristics more accurately, than conventional metrics such as the Hausdorff distance and Dynamic Time Warping distance. Quantitatively, based on the Davies-Bouldin index, the clustering results were found to be superior or comparable and demonstrated exceptional efficiency in computational distance calculation.

Trans-Aortic Flow Turbulence and Aortic Valve Inflammation: A Pilot Study Using Blood Speckle Imaging and 18F-Sodium Fluoride Positron Emission Tomography/Computed Tomography in Patients With Moderate Aortic Stenosis

  • Soyoon Park;Woo-Baek Chung;Joo Hyun O;Kwan Yong Lee;Mi-Hyang Jung;Hae-Ok Jung;Kiyuk Chang;Ho-Joong Youn
    • Journal of Cardiovascular Imaging
    • /
    • v.31 no.3
    • /
    • pp.145-149
    • /
    • 2023
  • BACKGROUND: 18F-sodium fluoride positron emission tomography/computed tomography (18F-NaF PET/CT) has been proven to be useful in identification of microcalcifications, which are stimulated by inflammation. Blood speckle imaging (BSI) is a new imaging technology used for tracking the flow of blood cells using transesophageal echocardiography (TEE). We evaluated the relationship between turbulent flow identified by BSI and inflammatory activity of the aortic valve (AV) as indicated by the 18F-NaF uptake index in moderate aortic stenosis (AS) patients. METHODS: This study enrolled 18 moderate AS patients diagnosed within the past 6 months. BSI within the aortic root was acquired using long-axis view TEE. The duration of laminar flow and the turbulent flow area ratio were calculated by BSI to demonstrate the degree of turbulence. The maximum and mean standardized uptake values (SUVmax, SUVmean) and the total microcalcification burden (TMB) as measured by 18F-NaF PET/CT were used to demonstrate the degree of inflammatory activity in the AV region. RESULTS: The mean SUVmean, SUVmax, and TMB were 1.90 ± 0.79, 2.60 ± 0.98, and 4.20 ± 2.18 mL, respectively. The mean laminar flow period and the turbulent area ratio were 116.1 ± 61.5 msec and 0.48 ± 0.32. The correlation between SUVmax and turbulent flow area ratio showed the most positive and statistically significant correlation, with a Pearson's correlation coefficient (R2) of 0.658 and a p-value of 0.014. CONCLUSIONS: The high degree of trans-aortic turbulence measured by BSI was correlated with severe AV inflammation.

Ensemble Projection of Climate Suitability for Alfalfa (Medicago Sativa L.) in Hamkyongbukdo (함경북도 내 미래 알팔파 재배의 기후적합도 앙상블 전망)

  • Hyun Seung Min;Hyun Shinwoo;Kim Kwang Soo
    • Journal of The Korean Society of Grassland and Forage Science
    • /
    • v.44 no.2
    • /
    • pp.71-82
    • /
    • 2024
  • It would be advantageous to grow legume forage crops in order to increase the productivity and sustainability of sloped croplands in Hamkyongbukdo. In particular, the identification of potential cultivation areas for alfalfa in the given region could aid decision-making on policies and management related to forage crop production in the future. This study aimed to analyze the climate suitability of alfalfa in Hamkyongbukdo under current and future climate conditions using the Fuzzy Union model. The climate suitability predicted by the Fuzzy Union model was compared with the actual alfalfa cultivation area in the northern United States. Climate data obtained from 11 global climate models were used as input data for calculation of climate suitability in the study region to examine the uncertainty of projections under future climate conditions. The area where the climate suitability index was greater than a threshold value (22.6) explained about 44% of the variation in actual alfalfa cultivation areas by state in the northern United States. The climatic suitability of alfalfa was projected to decrease in most areas of Hamkyongbukdo under future climate scenarios. The climatic suitability in Onseong and Gyeongwon County was analyzed to be over 88 in the current climate conditions. However, it was projected to decrease by about 66% in the given areas by the 2090s. Our study illustrated that the impact of climate change on suitable cultivation areas was highly variable when different climate data were used as inputs to the Fuzzy Union model. Still, the ensemble of the climate suitability projections for alfalfa was projected to decrease considerably due to summer depression in Hamkyongbukdo. It would be advantageous to predict suitable cultivation areas by adding soil conditions or to predict the climate suitability of other leguminous crops such as hairy vetch, which merits further studies.

Estimation of genetic correlations and genomic prediction accuracy for reproductive and carcass traits in Hanwoo cows

  • Md Azizul Haque;Asif Iqbal;Mohammad Zahangir Alam;Yun-Mi Lee;Jae-Jung Ha;Jong-Joo Kim
    • Journal of Animal Science and Technology
    • /
    • v.66 no.4
    • /
    • pp.682-701
    • /
    • 2024
  • This study estimated the heritabilities (h2) and genetic and phenotypic correlations between reproductive traits, including calving interval (CI), age at first calving (AFC), gestation length (GL), number of artificial inseminations per conception (NAIPC), and carcass traits, including carcass weight (CWT), eye muscle area (EMA), backfat thickness (BF), and marbling score (MS) in Korean Hanwoo cows. In addition, the accuracy of genomic predictions of breeding values was evaluated by applying the genomic best linear unbiased prediction (GBLUP) and the weighted GBLUP (WGBLUP) method. The phenotypic data for reproductive and carcass traits were collected from 1,544 Hanwoo cows, and all animals were genotyped using Illumina Bovine 50K single nucleotide polymorphism (SNP) chip. The genetic parameters were estimated using a multi-trait animal model using the MTG2 program. The estimated h2 for CI, AFC, GL, NAIPC, CWT, EMA, BF, and MS were 0.10, 0.13, 0.17, 0.11, 0.37, 0.35, 0.27, and 0.45, respectively, according to the GBLUP model. The GBLUP accuracy estimates ranged from 0.51 to 0.74, while the WGBLUP accuracy estimates for the traits under study ranged from 0.51 to 0.79. Strong and favorable genetic correlations were observed between GL and NAIPC (0.61), CWT and EMA (0.60), NAIPC and CWT (0.49), AFC and CWT (0.48), CI and GL (0.36), BF and MS (0.35), NAIPC and EMA (0.35), CI and BF (0.30), EMA and MS (0.28), CI and AFC (0.26), AFC and EMA (0.24), and AFC and BF (0.21). The present study identified low to moderate positive genetic correlations between reproductive and CWT traits, suggesting that a heavier body weight may lead to a longer CI, AFC, GL, and NAIPC. The moderately positive genetic correlation between CWT and AFC, and NAIPC, with a phenotypic correlation of nearly zero, suggesting that the genotype-environment interactions are more likely to be responsible for the phenotypic manifestation of these traits. As a result, the inclusion of these traits by breeders as selection criteria may present a good opportunity for developing a selection index to increase the response to the selection and identification of candidate animals, which can result in significantly increased profitability of production systems.