• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.4
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• pp.26-31
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• 2005

ITR(Inne. Tie Rod) is one of the core parts in an automobile steering system. The front wheels are connected to the steering system, which are controlled by steering wheel through the ITR. Improvement of assembling ITR is needed f3r drivers' satisfaction. Therefore, the parameters influencing the rotational torque were studied and analyzed. The useful results can be obtained, and could be applied to manufacture ITR. Through these manufacturing technologies, high quality ITR have been manufactured with high productivity.

• Journal of Life Science
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• v.29 no.12
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• pp.1345-1350
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• 2019

Our recent study has revealed that in vivo intestinal transit rate (ITR) in normal mice was significantly increased by the administration of an aqueous extract of dried Gentiana scabra rhizomes and roots (GS-W) in a dose-dependent manner. Following on from our previous study, the effect of GS-W on ITR was measured in mice with experimentally induced gastrointestinal motility dysfunctions (GMDs) in the present study. GS-W showed no significant acute toxicity even at an oral dose of 5 g/kg to mice. ITR was significantly retarded in the GMD mice compared with that in normal mice, and this retardation was significantly recovered by the oral administration of GS-W in a dose-dependent manner. Furthermore, the ITR value of GS-W at a dose of 1 g/kg appeared to be higher than that of cisapride, which was predominantly prescribed for human patients with various GMDs in the late 1900s but was withdrawn from the market in 2000 due to its fatal side effects. The current results suggest that GS-W is a potential substitute for cisapride to prevent or alleviate human GMDs.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.6
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• pp.297-302
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• 2022

The current study examines the relationship between inventory management efficiency and financial performance in Saudi Arabian companies. The study collected data from the companies listed on Tadawul (a Saudi Arabian stock exchange) during the period starting from 2016 and ending in 2020. The study uses pooled regression model by incorporating Return on Assets (ROA) and Inventory Turnover Ratio (ITR) as a performance measurement variable and inventory conversion period as an inventory management variable to report the results. The results show a positive and significant association between inventory management and firms' financial growth measured in terms of Return on Assets (ROA). Further, the study reports a positive and significant association between the inventory conversion period and inventory turnover (ITR). This shows that managing inventory efficiently shall positively impact the firm's performance. The other variables, such as debt ratio and gross profit, are positively related to ROA and negatively correlated with ITR. The firm growth is positively associated with both the dependent variables. The results suggest that the management of inventory in Saudi Arabian firms is efficient. Further, the firm size is positively associated with ROA and ITR. This shows a nexus between inventory management efficiency and firms' financial growth in Saudi Arabian companies.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.8
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• pp.2015-2020
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• 2009

$NO_x$ reduction of stationary exhaust was performed at atmospheric condition and the temperature ranging from $200^{\circ}C$ to $500^{\circ}C$ over ZSM-5 supported metal catalyst. The characteristics of the prepared catalysts were investigated using the analytical techniques such as SEM, XRD, EDX, ICP and ITR. The results of EDX and ICP analysis demonstrated that the most part of transition metal existed on the exterior surface of support. Maximum de-$NO_x$ yield over Fe/ZSM-5 shown between $380^{\circ}C$ and $400^{\circ}C$ was presumed to be due to the maximum H2 reduction rate at $400^{\circ}C$ of ITR.

• Journal of Korean Medicine for Obesity Research
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• v.17 no.2
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• pp.61-67
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• 2017

Objectives: The purpose of this study was to investigate the effects of Socheongryong-tang, a traditional herbal medicine, on gastrointestinal (GI) motility disorders (inflammatory and diabetic models) in mice. Methods: The in vivo effects of Socheongryong-tang on GI motility were investigated by calculating percent intestinal transit rates (ITR) and gastric emptying (GE) values using Evans Blue and phenol red, respectively, in normal mice and in mice with experimentally induced GI motility dysfunction (GMD). GMD models were induced by acetic acid and streptozotocin. Results: In normal ICR mice, ITR and GE values were significantly and dose-dependently increased by the intragastric administration of Socheongryong-tang (0.0025~0.25 g/kg). The ITR values (%) of GMD mice were significantly lower than those of normal mice, and these reductions were significantly and dose-dependently inhibited by Socheongryong-tang. Conclusions: These results suggest that Socheongryong-tang is a good candidate for the development of a prokinetic agent that may prevent or alleviate GMD.

• Electronics and Telecommunications Trends
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• v.28 no.2
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• pp.155-164
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• 2013

국제전기통신연합(ITU)은 2012년 12월, 세계국제전기통신회의(WCIT-12)에서 24년 만에 국제전기통신규칙(ITR)을 개정했다. 이번 회의에서 가장 관심을 집중시킨 것은 '인터넷 규제' 관련 조항이었다. ITR 개정에는 193개 회원국 가운데 89개국이 서명하고, 55개국은 서명을 거부했다. 서명을 주도한 국가는 러시아, 중국을 비롯해 중동, 남미 지역 국가들이며, 한국도 포함된다. 반면 미국, 영국, 캐나다를 포함, 유럽 국가들은 서명을 거부했다. 결국 서방 국가들의 반발로 개정 조문에는 인터넷 규제 관련 조문은 삽입되지 못했고, 정보 보호나 스팸 방지 등의 문제에 회원국들이 공조할 수 있다는 선언적 의미만 들어가게 되었다. 따라서 당장 인터넷 규제 방식에 큰 변화는 수반되지 않을 것으로 전망되며, 인터넷 규제에 관한 논의는 2013년 서울 사이버 스페이스 총회, 2014년 부산 ITU 전권회의 등의 국제회의에서 지속적으로 논의될 것으로 보인다.

• Proceedings of the KIEE Conference
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• 2000.07b
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• pp.587-589
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• 2000

In this paper, the stability criterion for cryocooler-cooled high-temperature superconducting (HTS) coils is discussed. We choose the current, Itr at which "thermal runaway" occurs, as a stability criterion and adopt the relationship between the cooling power of GM cryocooler and the heat generation in coil system to evaluate Itr. We also investigate the transient behavior during a quench process in HTS coils by a newly developed FEM computer program.

• Integrative Medicine Research
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• v.6 no.2
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• pp.149-155
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• 2017

Background: Naringenin (NRG) is a common dietary polyphenolic constituent of fruits. NRG has diverse pharmacological activities, and is used in traditional medicine to treat various diseases including gastrointestinal (GI) disorders. Interstitial cells of Cajal (ICCs) are pacemaker cells of the GI tract. In this study, the authors investigated the effects of NRG on ICCs and on GI motility in vitro and in vivo. Methods: ICCs were dissociated from mouse small intestines by enzymatic digestion. The whole-cell patch clamp configuration was used to record pacemaker potentials in cultured ICC clusters. The effects of NRG on GI motility were investigated by calculating percent intestinal transit rates (ITR) using Evans blue in normal mice. Results: NRG inhibited ICC pacemaker potentials in a dose-dependent manner. In the presence of tetraethylammonium chloride or iberiotoxin, NRG had no effect on pacemaker potentials, but it continued to block pacemaker potentials in the presence of glibenclamide. Preincubation with SQ-22536 had no effect on pacemaker potentials or on their inhibition by NRG. However, 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one blocked pacemaker potential inhibition by NRG. In addition, L-NG-nitroarginine methyl ester blocked pacemaker potential inhibition by NRG. Furthermore, NRG significantly suppressed murine ITR enhancement by neostigmine in vivo. Conclusion: This study shows NRG dose-dependently inhibits ICC pacemaker potentials via a cyclic guanosine monophosphate/nitric oxide-dependent pathway and $Ca^{2+}$-activated $K^+$ channels in vitro. In addition, NRG suppressed neostigmine enhancement of ITR in vivo.

• Journal of Life Science
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• v.26 no.11
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• pp.1253-1258
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• 2016

Although major advances have been achieved in our understanding and treatment of diseases in many areas of medicine, relatively few improvements have been made in the area of gastrointestinal (GI) motor function. The dried root of Codonopsis pilosula (Franch.) Nannf. (CP) has been used as a traditional folk medicine for improving poor GI function in East Asia, including China and Korea. In the present study, neither aqueous (CP-W) nor ethanolic (CP-E) extracts of CP showed significant toxicity, even at an oral dose of 5 g/kg to mice. The effects of CP-W and CP-E on GI motor function were investigated by measuring in vivo the gastric emptying rate (GER) and intestinal transit rate (ITR) in mice. In normal mice, the ITR was significantly increased by CP-W in a dose-dependent manner, whereas the GER was not significantly affected by any CP extracts. The ITR was significantly retarded in the mice with experimental GI motility dysfunction (i.e., peritoneal irritation by acetic acid) compared with that in normal mice. However, the retardation was significantly recovered by the pre-treatment of CP-W in a dose-dependent manner. The above results suggest that CP-W might be a potential prokinetic agent preventing or alleviating GI motility dysfunctions in human patients.

• Journal of Life Science
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• v.24 no.3
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• pp.260-265
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• 2014

Dried Citrus unshiu peels (Aurantii Nobilis Pericarpium; ANP) are used as a traditional folk medicine for the treatment of gastrointestinal (GI) motility disorders in East Asia, including Korea. In the present study, an ethanolic extract of ANP (ANP-E) exhibited no significant toxicity in mice, even at an oral dose of 5 g/kg. The effects of ANP-E on GI motor function were investigated by measuring the intestinal transit rate (ITR) of Evans blue in normal mice and mice with experimental GI motility dysfunction (i.e., peritoneal irritation by acetic acid; PIA). In normal mice, ANP-E significantly increased the ITR in a dose-dependent manner. The ITR in the PIA mice was significantly retarded compared to that in the normal mice. However, ANP-E significantly inhibited this retardation in a dose-dependent manner. Furthermore, in all the models, the potency of ANP-E appeared to be same or higher than that of cisapride, which was used predominantly for the treatment of various GI motility disorders in humans in the 1900s but was removed from the market in 2000 due to fatal side effects. The results suggest that ANP-E has potential as a new prokinetic agent that could be used as a substitute for cisapride.