• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.3
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• pp.1778-1785
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• 2014

In order to construct offshore structures safely, geotechnical investigation should be carried out with high accuracy. Up to now, onshore geotechnical investigation equipments installed on the barge are used for offshore geotechnical investigation. In this case, many limitations can be confronted such as deep water depth, high wave, strong current, severe wind and so on. For the safe and economic offshore geotechnical investigation with high precision, a seabed type unmanned automated site investigation equipment is developed. It can be operated remotely underwater conditions with 100m water depth and can explore the ground depth of 50m. Also, the standard penetration test (SPT), soil boring, soil sampling and rock coring can be possible using the equipment. Numerical analysis was conducted to secure the stability of the equipment against current of 4 knot. Energy efficiency of SPT apparatus which is attached to the equipment shows 78% in average.

• The KIPS Transactions:PartC
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• v.17C no.1
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• pp.89-98
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• 2010

In current digital broadcasting systems, GEM(Globally Executable MHP)-based middlewares such as MHP(Multimedia Home Platform), OCAP(OpenCable Application Platform), ACAP(Advanced Common Application Platform) are the norm. Despite much of the common characteristics shared, such as MPEG-2 and DSM-CC(Digital Storage Media-Command and Control) protocols, the information and data structures they need are slightly different, which results in incompatibility issues. In this paper, in line with an effort to develop an integrated DTV middleware, we propose a general-purpose, reconfigurable DSM-CC architecture for supporting various standard GEM-based middlewares without code modifications. First, we identify DSM-CC components that are common and thus can be shared by all GEM-based middlewares. Next, the system is provided with middleware-specific information and data structures in the form of XML. Since the XML information can be parsed dynamically at run time, it can be interchanged either statically or dynamically for a specific target middleware. As for the performance issues, the response time and usage frequency of DSM-CC module highly contribute to the performance of STB(Set-Top-Box). In this paper, we also propose an efficient application cache management strategy and evaluate its performance. The performance result has shown that the cache strategy reflecting user preferences greatly helps to reduce response time for executing application.

• KIPS Transactions on Software and Data Engineering
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• v.2 no.9
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• pp.603-614
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• 2013

The popularity of mobile devices provides their users with a circumstance that services and information can be accessed wherever and whenever users need. Accordingly, various studies have been proposed personalized methods to improve accessibility of mobile users to information. However, since these personalized methods require users' private information, they gives rise to problems on security. An efficient way to resolve security problems is to estimate user information by using their online and offline behavior. In this paper, for this purpose, it is proposed a novel user information identification system that identifies users' personal and social information by using both his/her behavior on social network services and proximity patterns obtained from GPS data. In the proposed system, personal information of a user like age, gender, and so on is estimated by analyzing SNS texts and POI (Point of Interest) patterns, while social information between a pair of users like family and friend is predicted with proximity patterns between the users. Each identification module is efficiently designed to handle the characteristics of user data like much noise in SNS texts and missing signals in GPS data. In experiments to evaluate the proposed system, our system shows its superiority against ordinary identification methods. This result means that the proposed system can efficiently reflect the characteristics of user data.

• Journal of the Korea institute for structural maintenance and inspection
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• v.19 no.1
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• pp.120-127
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• 2015

The purpose of this study is to improve the fire prevention performance using the fire venetian blind louver subjected to burning by fire flame. The investigation is based on testing 2 full scale specimens, which is $3m{\times}3m$ module, $850mm{\times}1,500mm$ open, and $900mm{\times}900mm{\times}175mm$ venetian blind louver. Two louver thickness (1.5 and 2.0mm) were adopted. The specimens were exposed to fire flame temperature levels of ISO834 at the lower surface of the fire venetian blind louver specimens with exposure duration of one hour in Korea Institute of Construction Technology (KICT). It was found from the test results that the values of distributed temperature, decreased for all specimens for protecting to fire flame by venetian blind louver. The results of tests were a good fire prevention performance between in initial to 6 mins. At 60 minutes around ISO 834 fire loading, the percentages of distributed temperature in 500mm and 800mm height ranged between 11 and 10% respectively, regardless of louver thickness. This study, therefore, will improve the fire venetian blind louver for fire protection and prevention performance.

• Design & Manufacturing
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• v.13 no.4
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• pp.10-16
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• 2019

Semiconductor chip is bonded to the substrate by melting solder bumps. In general, the chip bonding is applied by a Reflow process or a Thermo-Compression(TC) bonding process. In this paper, we introduce a Laser Assisted Thermo-Compression bonding (LATCB) process to improve the anxiety of the existing process(Reflow, TC bonding). In the LATCB process, the chip is bonded to the substrate by irradiating a laser with a uniform energy density in the same area as the chip to melt only the solder bumps and press the chip with a Transparent Compression Module (TCM). The TCM consists of a fused silica header for penetrating the laser and pressurizing the chip, and a piezoelectric actuator (P.A.) coupled to both ends of the header for micro displacement control of the header. In addition, TCM is a structure that can pressurize the chip and deliver it to the chip and solder bumps without losing the energy of the laser. Fused silica, which is brittle, is vulnerable to deformation, so the header may be damaged when an external force is applied for pressurization or a displacement differenced is caused by piezoelectric actuators at both ends. On the other hand, in order to avoid interference between the header and the adjacent chip when pressing the chip using the TCM, the header has a notch at the bottom, and breakage due to stress concentration of the notch is expected. In this study, the thickness and notch length that the header does not break when the external force (500 N) is applied to both ends of the header are optimized using structural analysis and Coulomb-Mohr failure theory. In addition, the maximum displacement difference of the P.A.s at both ends where no break occurred in the header was derived. As a result, the thickness of the header is 11 mm, and the maximum displacement difference between both ends is 8 um.

• Science of Emotion and Sensibility
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• v.6 no.4
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• pp.15-23
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• 2003

Recently, there have been many attempts to develop BCI (brain computer interface) based on EEG (electroencephalogram). Measurement and analysis of EEG evoked by particular stimulation is important for the design of brain wave pattern and interface of BCI. The purpose of this study is to develop a general-purpose system that measures subject's reaction time after audio-visual stimulation which can work together with any other biosignal measurement systems. The entire system is divided into four modules, which are stimulation signal generation, reaction time measurement, evoked potential measurement and synchronization. Stimulation signal generation module was implemented by means of Flash. Measurement of the reaction time (the period between the answer request and the subject reaction) was achieved by self-made microcontroller system. EEG measurement was performed using the ready-made hardware and software without any modification. Synchronization of all modules was achieved by, first, the black-and-white signals on the stimulation screen synchronized with the problem presentation and the answer request, second, the photodetectors sensing the signals. The proposed method offers easy design of purpose-specific system only by adding simple modules (reaction time measurement, synchronization) to the ready-made stimulation and EEG system, and therefore, it is expected to accelerate the researches requiring the measurement of evoked response and reaction time.

• Toxicological Research
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• v.20 no.2
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• pp.89-100
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• 2004

The comet assay (also called the single-cell gel electrophoresis assay) has been widely used for detecting DNA damage and repair in individual cells. Since the conventional methods of evaluating comet assay data using frequency statistics are unsatisfactory we developed a new quantitative measure of DNA damage/repair that is based on all information residing in the dose/time-response curves of a comet experiment. Blood samples were taken from 25 breast cancer patients before undergoing radiotherapy. The comet assay was performed under alkaline conditions using isolated lymphocytes. Tail DNA, tail length, tail moment and tail inertia of the comet were measured for each patient at four doses of $\gamma$-rays (0, 2, 4 and 8 Gy) and at four time points after irradiation (0, 10, 20 and 30 min) using 100 cells each. The resulting three-dimensional dose-time response surface was modeled by multiple regression, and the second derivative, termed 2D, on dose and time was determined. A software module was programmed in SAS/AF to compute 2D values. We applied the new method successfully to data obtained from cancer patients to be assessed for their radiation sensitivity. We computed the 2D values for the four damage measures, i.e., tail moment, tail length, tail DNA and tail inertia, and examined the pairwise correlation coefficients of 2D both on the log scale and the unlogged scale. 2D values based on tail moment and tail DNA showed a high correlation and, therefore, these two damage measures can be used interchangeably as far as DNA repair is concerned. 2D values based on tail inertia have a correlation profile different from the other 2D values which may reflect different facets of DNA damage/repair. Using the dose-time response surface, other statistical models, e.g., the proportional hazards model, become applicable for data analysis. The 2D approach can be applied to all DNA repair measures, Le., tail moment, tail length, tail DNA and tail inertia, and appears to be superior to conventional evaluation methods as it integrates all data of the dose/time-response curves of a comet assay.

• Fire Science and Engineering
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• v.30 no.4
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• pp.111-120
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• 2016

This is an experimental study to analyze the explosion and fire hazards of mobile phone batteries. Using the lithium-ion batteries currently used on smart phone as the experiment samples, the experiments were conducted by overcharging, internal and external short circuit, and thermal shock with the potential of explosion and fire caused by careless use or abnormal conditions. The experiment results showed that, in the case of overcharging and external short circuit, there was no explosion and fire hazard in the normal operation of the protection circuit module (PCM), but there were big risks when the PCM faulted conditions were assumed. In the case of the experiments by internal short circuit and thermal shock, such risks varied depending on a battery charge state. In other words, it could be verified that there were low risks of explosion and fire in a full discharge state, but there were high risks in a full charge state. These experiment results suggest that to minimize the explosion and fire hazards of mobile phone batteries, an alarm device is necessary when the PCM fault occurs. In addition, a solid battery case should be made and safety equipment, such as a cooling device to avoid high temperature, is needed.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2002.07a
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• pp.113-113
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• 2002

Phylogenetically conserved Bcl-2 family proteins play a pivotal role in the regulation of apoptosis from virus to human. Members of the Bcl-2 family consist of antiapoptotic proteins such as Bcl-2, Bcl-xL, and Bcl-w, and proapoptotic proteins such as BAD, Bax, BOD, and Bok. It has been proposed that anti- and proapoptotic Bcl-2 proteins regulate cell death by binding to each other and forming heterodimers. A delicate balance between anti- and proapoptotic Bcl-2 family members exists in each cell and the relative concentration of these two groups of proteins determines whether the cell survives or undergoes apoptosis. Mcl-1 (Myeloid cell :leukemia-1) is a member of the Bcl-2 family proteins and was originally cloned as a differentiation-induced early gene that was activated in the human myeloblastic leukemia cell line, ML-1 . Mcl-1 is expressed in a wide variety of tissues and cells including neoplastic ones. We recently identified a short splicing variant of Mcl-1 short (Mcl-IS) and designated the known Mcl-1 as Mcl-1 long (Mcl-lL). Mcl-lL protein exhibits antiapoptotic activity and possesses the BH (Bcl-2 homology) 1, BH2, BH3, and transmembrane (TM) domains found in related Bcl-2 proteins. In contrast, Mcl-1 S is a BH3 domain-only proapoptotic protein that heterodimerizes with Mcl-lL. Although both Mc1-lL and Mcl-lS proteins contain BH domains fecund in other Bcl-2 family proteins, they are distinguished by their unusually long N-terminal sequences containing PEST (proline, glutamic acid, serine, and threonine) motifs, four pairs of arginine residues, and alanine- and glycine-rich regions. In addition, the expression pattern of Mcl-1 protein is different from that of Bcl-2 suggesting a unique role (or Mcl-1 in apoptosis regulation. Tankyrasel (TRF1-interacting, ankyrin-related ADP-related polymerasel) was originally isolated based on its binding to TRF 1 (telomeric repeat binding factor-1) and contains the sterile alpha motif (SAM) module, 24 ankyrin (ANK) repeats, and the catalytic domain of poly(adenosine diphosphate-ribose) polymerase (PARP). Previous studies showed that tankyrasel promotes telomere elongation in human cells presumably by inhibiting TRFI though its poly(ADP-ribosyl)action by tankyrasel . In addition, tankyrasel poly(ADP-ribosyl)ates Insulin-responsive amino peptidase (IRAP), a resident protein of GLUT4 vesicles, and insulin stimulates the PARP activity of tankyrase1 through its phosphorylation by mitogen-activated protein kinase (MAPK). ADP-ribosylation is a posttranslational modification that usually results in a loss of protein activity presumably by enhancing protein turnover. However, little information is available regarding the physiological function(s) of tankyrase1 other than as a PARP enzyme. In the present study, we found tankyrasel as a specific-binding protein of Mcl-1 Overexpression of tankyrasel led to the inhibition of both the apoptotic activity of Mel-lS and the survival action of Mcl-lL in mammalian cells. Unlike other known tankyrasel-interacting proteins, tankyrasel did not poly(ADP-ribosyl)ate either of the Mcl-1 proteins despite its ability to decrease Mcl-1 proteins expression following coexpression. Therefore, this study provides a novel mechanism to regulate Mcl-1-modulated apoptosis in which tankyrasel downregulates the expression of Mcl-1 proteins without the involvement of its ADP-ribosylation activity.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.29 no.5
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• pp.247-259
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• 2017

Numerical model with LPT (Lagrangian Particle Tracking) module was used to understand the variation of residence time in the outer sea of the Sihwa lake result operating from the Sihwa tidal power plant. Numerical model was composed in order to investigate the spatial distribution characteristics, the average residence time in each area was calculated by dividing the outer sea area of Sihwa lake into 4 areas. The average residence time of the areas appeared to be increase as it entered the areas located in the inner bay (13 days) from the area located in most outer sea (3 days) both before and during operation. Variation of average residence time by areas were increased in the area that was located in the most outer sea of during operation compared to before operation, and decreased in the other area. Artificial discharges from tidal power plant induces particle traps in the formation of vortex in the area located in the most outer seas, entrainment in the remaining areas, which affects variation in residence time. In other words, the jet flow generated during drainage and the change in the residence time due to the vortex and entrainment action indicate the increase horizontal mixing of water in the outer sea and in the inner bay.