• Pediatric Infection and Vaccine
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• v.24 no.1
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• pp.16-22
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• 2017

Purpose: We suspect there is a difference in the clinical manifestations and treatment response to antiviral drugs for influenza A and B. This study was conducted to investigate this difference. Methods: We collected information on pediatric patients, infected with the influenza virus, admitted to Dongguk University Ilsan Hospital from October 2013 to May 2015. We investigated the clinical manifestations of influenza and differences in treatment response to oseltamivir treatment for the two types of influenza. Results: A total of 138 patients were included. The mean age was $3.5{\pm}4.0$ years. When comparing the diseases associated with influenza A and B, croup (19.2% vs. 1.7%, P=0.001) was more common with influenza A infection. Myositis (0% vs. 6.7%, P=0.021) and gastroenteritis (29.5% vs. 46.7%, P=0.038) were more common with influenza B infection. When comparing the total fever duration from the start of oseltamivir administration, patients treated with oseltamivir within 2 days of fever had the shortest duration. Among the patients treated with oseltamivir, the duration of fever, after the start of oseltamivir treatment, for was shorter for influenza A infection than for influenza B infection ($16.0{\pm}19.1$ hours vs. $28.9{\pm}27.9$ hours, P=0.006). Conclusions: There appear to be differences in the accompanying diseases and antiviral medication responses between the two types of influenza. It is important to administer oseltamivir within 2 days of fever.

• Journal of radiological science and technology
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• v.27 no.3
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• pp.31-41
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• 2004

Attention deficit hyperactivity disorder(ADHD)is one of the most common psychiatric disorders in childhood, especially school age children and persisting into adult. ADHD is affected 7.6% in our children, Korea. and persisting into $15{\sim}20%$ in adult. And it is characterized by hyperactivity, inattention and impulsivity. Brain imaging is one of way to diagnosis for ADHD. Brain imaging studies may be provide information two types - structural and functional imaging. Structural and functional images of the brain play an important role in management of neurologic and psyciatric disorders. Brain SPECT, with perfusion imaging radiopharmaceuticals is one of the appropriate test to diagnosis of neurologic and psychiatric diseases. Ther are a few studies about separated analysis between boys and girls ADHD SPECT brain images. Selection of Probability level(P-value) is very important to determind the abnormalities when analysis a data by SPM. SPM is a statistical method used for image analysis and determine statistical different between two groups-normal and ADHD. Commonly used P-value is P<0.05 in statistical analysis. The purpose of this study is to evaluation of blood flow clusters distribution, between boys and girls ADHD. The number of normal boys are 8(6-7y, average : $9.6{\pm}3.9y$) and 51(4-11y, average : $9.0{\pm}2.4$) ADHD patients, and normal girls are 4(6-12y, average : $9{\pm}2.4y$) and 13(2-13y, average $10{\pm}3.5y$) ADHD patiens. Blood flow tracer $^{99m}Tc-ethylcysteinate$ dimer(ECD) injected as rCBF agent and take blood flow images after 30 min. during sleeping by SPECT camera. The anatomical region of hyperperfusion of rCBF in boys ADHD group is posterior cingulate gyrus and hyperperfusion rate is 15.39-15.77% according to p-value. And girls ADHD group appears at posterior cerebellum, Lt. cerbral limbic lobe and Lt. Rt. cerebral temporal lobe. These areas hyperperfusion rate are 24.68-31.25%. Hypoperfusion areas in boys ADHD,s brain are Lt. cerebral insular gyrus, Lt. Rt. frontal lobe and mid-prefrontal lobe, these areas decresed blood flow as 15.21-15.64%. Girls ADHD decreased blood flow regions are Lt. cerebral insular gyrus, Lt. cerebral frontal and temporal lobe, Lt. Rt. lentiform nucleus and Lt. parietal lobe. And hypoperfusion rate is 30.57-30.85% in girls ADHD. The girls ADHD group's perfusion rate is more variable than boys. The studies about rCBF in ADHD, should be separate with boys and girls.

• Journal of radiological science and technology
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• v.37 no.2
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• pp.125-134
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• 2014

This study is to provide basic information regarding photoneutron doses in terms of radiation treatment techniques and the number of portals in intensity-modulated radiation therapy (IMRT) by measuring the photoneutron doses. Subjects of experiment were 10 patients who were diagnosed with prostate cancer and have received radiation treatment for 5 months from September 2013 to January 2014 in the department of radiation oncology in S hospital located in Seoul. Thus, radiation treatment plans were created for 3-Dimensional Conformal Radiotherapy (3D-CRT), Volumetric-Modulated Arc Radiotherapy (VMAT), IMRT 5, 7, and 9 portals. The average difference of photoneutron dose was compared through descriptive statistics and variance analysis, and analyzed influence factors through correlation analysis and regression analysis. In summarized results, 3D-CRT showed the lowest average photoneutron dose, while IMRT caused the highest dose with statistically significance (p <.01). The photoneutron dose by number of portals of IMRT was $4.37{\pm}1.08mSv$ in average and statistically showed very significant difference among the number of portals (p <.01). Number of portals and photoneutron dose are shown that the correlation coefficient is 0.570, highly statistically significant positive correlation (p <.01). As a result of the linear regression analysis of number of portals and photoneutron dose, it showed that photoneutron dose significantly increased by 0.373 times in average as the number of portals increased by 1 stage. In conclusion, this study can be expected to be used as a quantitative basic data to select an appropriate IMRT plans regarding photoneutron dose in radiation treatment for prostate cancer.

• Korean Journal of Weed Science
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• v.1 no.1
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• pp.44-51
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• 1981

An experiment was conducted to obtain the basic information about competitive ability of rice against weeds as affected by culm length at the Yeongnam Crop Experiment Station, Office of Rural Development in 1980. More weeds were harvested from the plot of short statured cultivar, Manseogbyeo compared to the plot of Cheongcheongbyeo that was approximately 10cm taller than Manseogbyeo regardless of planting density variables. Weeds also decreased as rice population increased from $30{\times}15cm$, $40{\times}(10{\times}10cm)$ and to $10{\times}10cm$, in order. The degree of weed suppression and floristic composition was varied depending upon plant spacing and weeding regime subjected at the previous year. The degree of weed suppression became increased with increasing rice population. The degree of weed suppression at the $10{\times}10cm$ plant spacing showed as high as hand weeding subjected in the previous year. However, in terms of floristic composition, Scirpus hotarui Roxb. became dominant when rice had cultivated at $10{\times}10cm$ plant spacing in the previous year while S. hotarui and Sagittaria pygmaea Miq. were both important in the hand weeding plot. The highest grain yield of rice showed at the $10{\times}10cm$ plant spacing while no significant difference was observed between $40{\times}(10{\times}10cm)$ and $30{\times}15cm$ plant spacings for both weeding regimes and both cultivars. However, response of grain yield to weeding regime was differed in two cultivars. For Manseobgyeo, significant grain yield decreased in no weeding plot regardless of plant spacing variables. But in case of Cheongcheongbyeo, grain yield reduction was only recognized at the $30{\times}15cm$ plant spacing. Based on these result it could be concluded that Cheongcheongbyeo (10cm taller in height) seemed to be more competitive against weeds than Manseogbyeo.

• Journal of the Korean Wood Science and Technology
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• v.42 no.6
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• pp.635-645
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• 2014

The anatomical characteristics of eight major wood species planted in Indonesia were investigated to provide valuable information for their effective utilization. The growth-ring boundaries of Damar and Sumatran pine were indistinct. Resin canal was found in Sumatran pine but it was not observed in Damar. Cupressoid pit and taxodioid pit were found in Damar and window-like pit and pinoid pit were observed in Sumatran pine. Tracheid length of Damar and Sumatran pine was shorter than $3,000{\mu}m$. There were uniseriate rays in Damar and Sumatran pine and fusiform ray in Sumatran pine. All the hardwood species observed in this study were diffuse-porous. They had different vessel groups, i.e., solitary pore in Afrika and Simpur Batu, pore cluster in Angsana and mostly 2-4 rows of radial pore multiple in Mahoni. Mindi and Trembesi had mostly 2-3 rows of radial pore multiple with paratracheal parenchyma as aliform and confluent types. Afrika, Mahoni and Simpur Batu showed heterocellular rays which composed of procumbent cells in the body and mostly 1-2 rows of upright and/or square cells in the margin. All ray cells procumbent was observed in Angsana, Mindi and Trembesi. The large rays commonly exceeding 1 mm in height and ray width of 3~6 cells were observed in Simpur Batu. The other five hardwood species showed ray width of 1~3 cells. Vessel number per $mm^2$ of Angsana and Simpur Batu was higher than those of the other hardwood species. The length of wood fiber and tracheid showed a tendency to increase from pith to bark. By IAWA list, fiber length of hardwoods was classified into long in Simpur Batu and short in Angsana and Trembesi.

• The Korean Journal of Nuclear Medicine
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• v.33 no.1
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• pp.100-109
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• 1999

Purpose: Preamplifier and amplifier are very important parts for developing a portable counting or imaging gamma probe. They can be used for analyzing pulses containing energy and position information for the emitted radiations. The commercial Nuclear Instrument Modules (NIMs) can be used for processing these pulses. However, it may be improper to use NIMs in developing a portable gamma probe, because of its size and high price. The purpose of this study was to develop both preamplifier and amplifier and measure their performance characteristics. Materials and Methods: The preamplifier and amplifier were designed as a charge sensitive device and a capacitor resistor-resistor capacitor (CR-RC) electronic circuit, respectively, and they were mounted on a print circuit board (PCB). We acquired and analyzed energy spectra for Tc-99m and Cs-137 using both PCB and NIMs. Multichannel analyzer (Accuspec/A, Canberra Industries Inc., Meriden Connecticut, U.S.A) and scintillation detectors (EP-047(Bicron Saint-Gobain/Norton Industrial EP-047 (Ceramics Co., Ohio, U.S.A) with $2"{\times}2"$ NaI(T1) crystal and R1535 (Hamamatsu Photonics K.K., Electron Tube Center, Shizuoka-ken, Japan) with $1"{\times}1"$ NaI(T1) crystal were used for acquiring the energy spectra. Results: Using PCB, energy resolutions of EP-047 detectors for Tc-99m and Cs-137 were 12.92% and 5.01%, respectively, whereas R1535 showed 13.75% and 5.19% of energy resolution. Using the NIM devices, energy resolutions of EP-047 detector for Tc-99m and Cs-137 were measured as 14.6% and 7.58%, respectively. However, reliable energy spectrum of R1535 detector could not be acquired, since its photomultiplier tube (PMT) requires a specific type of preamplifier. Conclusion: We developed a special preamplifier and amplifier suitable for a small sized gamma probe that showed good energy resolutions independent of PMT types. The results indicate that the PCB can be used in developing both counting and imaging gamma probe.

• The Korean Journal of Nuclear Medicine Technology
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• v.12 no.1
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• pp.91-98
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• 2008

Purpose: Radio-isotopes (RI) use has been steadily developing due to industrial and technical development in the modern medical society. Particularly, popularization of domestic cyclotrons dramatically enable hospitals to produce and use diagnostic radio-isotopes. Generally, only specific facilities such as hospitals, research institutes, nuclear power plants and universities can use radio-isotopes, they are also responsible for ventilation system. The strength of radioactivity in the air is strongly regulated and controlled by korea atomic energy law in Korea Institue of Nuclear Safety (KINS), so that air radioactivity exposure can lead to environmental pollution surrounding places. In this study, we'd like to find out the investigation and the present condition of the controlled ventilation system in domestic hospitals by an emission standard from KINS, and try to reach an agreement about how to use the ventilation system. Result: Definition of filters, features and structures of pre-filters, hepa-filters, charcol filters, filter exchange procedures and precautions are explained. RI deflation concentration and filter exchange cycle have been presented as a standard prescribed in the rules of KINS. The Radiation Control Management System (RCMS) introduced by Seoul National University Bundang Hospital linking to digital pressure gauge with computer controller in another medical facilities were described in details. Conclusions: The system of medical facilities using RI has been remarkably developing in 21 century. Especially, radiation safety control system has also been grown rapidly into the subdivision, specialization, advanced technology along with international technical improvement. However, As far as current RI ventilation system is concerned, it has nothing better than doing in the past. Preferentially, to reinforce this, more sophisticated system with strict periodic filter exchange and exhaust air control guidance should be introduced by applying brilliant domestic information technology for RCMS and digital gauge method. From personal point of view as a radiation safety manager, I have provide with present problems and improvements. Futhermore, more improved guidance should be conducted.

• Korean Journal of Food Science and Technology
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• v.39 no.4
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• pp.438-446
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• 2007

The fermented soybean product, cheonggukjang, is favored by many people, partly due to its bio-functional ingredients. Since the fermentation process of cheonggukjang is mediated by enzymes, including proteases, produced by microbes, analysis of the proteome profile changes in cheonggukjang during fermentation would provide us with valuable information for fermentation optimization, as well as a better understanding of the formation mechanisms of the bio-functional substances. The soluble proteins from cheonggukjang were prepared by a phenol/chloroform extraction method, in order to remove interfering molecules for high resolution 2-D gel analysis. Proteomic analysis of the cheonggukjang different fermentation periods suggested that most of the soluble soy proteins were degraded into smaller forms within 20hr, and many microbial proteins, such as mucilage proteins, dominated the soluble protein fraction. The proteomic profile of cheonggukjang was very different from natto, in terms of the 2-D gel protein profile. Among the separated protein spots on the 2-D gels, 50 proteins from each gel were analyzed by MALDI-TOF MS and PMF for protein identification. Due to database limitations with regard to soy proteins and microbial proteins, identification of the changed proteins during fermentation was restricted to 9 proteins for cheonggukjang and 15 for natto. From de novo sequencing of the proteins by a tandem MS/MS, as well as by database searches using BLASTP, a limited number of proteins were identified with low reliability. However, the 2-D gel analysis of proteins, including protein preparation methods, remains a valuable tool to analyze complex mixtures of proteins entirely. Also, for intensive mass spectrometric analysis, it is also advisable to focus on a few of the interestingly changed proteins in cheonggukjang.

• Journal of Hospice and Palliative Care
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• v.10 no.4
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• pp.195-201
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• 2007

Purpose: As a part of the analysis of home-based cancer patients management of public health renters in cities, counties and districts across the nation, this study is to understand the degree of patient demands for that management and the degree and scope of the supply for the patient's demand. Methods: Developed the questionnaire which was constituted of degree of demand and supply for home-based cancer patient management and analyzed data centering on the frequencies and percentages by utilizing SPSS WIN 12.0. Results: The services provided through the home-based cancer patients management project include physical, emotional, spiritual and education/informative services. A survey was conducted for home-based cancer patients about these services, and its result showed that the degree of demand and supply was highest for emotional service, followed by education/informative service, spiritual service and physical service in the order of the demand-supply degree. When main items for each service were examined, it was found that: in the case of physical service, pain control was provided murk lower than its demand, while excretion disorder control and individual hygiene is provided murk more than its demand. In the case of emotional service, the degree of demand was overall higher than that of supply; spiritual service was provided appropriately to the degree of demand. Conclusion: This study examines the home-based canter patients management project of public health centers and compares and analyzes the degree of demand for patient services and the degree of services that are actually provided. The findings could be used as based data for the development of effective programs in future on the basis of actual demands of home-based cancer patients.

• Horticultural Science & Technology
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• v.31 no.6
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• pp.720-725
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• 2013

When highly shrinkable materials such as coir dust are major component of root media, the degrees of compaction during container filling of root media severely influences the physical properties of root media. It results in the changes in total porosity (TP), container capacity (CC) and air-filled porosity (AFP). This research was conducted to secure the fundamental information in changes of soil physical properties as influenced by the compaction of root media during container filling. To achieve this, three root media were formulated by blending coir dust (CD) with expanded rice hull (CD + ERH, 8:2, v/v), carbonized rice hull (CD + CRH, 6:4) and ground and raw pine bark (CD + GRPB, 8:2). Based on the optimum bulk density, the amount of root media filled into 6.0, 7.5, 8.5, 10.5 and 12.5 cm were adjusted to 90, 100, 110, 120 and 130% based on the weight of root media. Then the changes in TP, CC, and AFP were measured. Elevation of the packing amount of root media in all sizes of pot resulted in the decrease of TP. But the decrease was more severe in CD + ERH and CD + CRH than those in CD + GRPB. The CC also decreased gradually as the packing amounts were elevated in three root media, but the decreases were severe as the container sizes became larger. The AFP decreased drastically by the elevation of the packing amount of root media in all sizes of pot. The AFP was the highest in CD + CRH medium when pot sizes were smaller than 7 cm, but that was the highest in CD + ERH when the pot sizes were larger than 8.5 cm among the 3 root media tested. In this research, the elevation of packing amount of three root media influenced more severely the AFP rather than CC. This result indicates that the packing amount should be controlled to maintain appropriate level of AFP because AFP rather than CC influence severely crop growth. The results obtained through this study can be used to predict the changes in physical properties of root media as influenced by packing amount in various sizes of pots.