• Korean Journal of Clinical Laboratory Science
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• v.56 no.1
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• pp.10-20
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• 2024

RNA-sequencing (RNA-seq) is a technique used for providing global patterns of transcriptomes in samples. However, it can only provide the average gene expression across cells and does not address the heterogeneity within the samples. The advances in single-cell RNA sequencing (scRNA-seq) technology have revolutionized our understanding of heterogeneity and the dynamics of gene expression at the single-cell level. For example, scRNA-seq allows us to identify the cell types in complex tissues, which can provide information regarding the alteration of the cell population by perturbations, such as genetic modification. Since its initial introduction, scRNA-seq has rapidly become popular, leading to the development of a huge number of bioinformatic tools. However, the analysis of the big dataset generated from scRNA-seq requires a general understanding of the preprocessing of the dataset and a variety of analytical techniques. Here, we present an overview of the workflow involved in analyzing the scRNA-seq dataset. First, we describe the preprocessing of the dataset, including quality control, normalization, and dimensionality reduction. Then, we introduce the downstream analysis provided with the most commonly used computational packages. This review aims to provide a workflow guideline for new researchers interested in this field.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.501-506
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• 2024

Humans have been shown to engage in multitasking behavior when searching for information on two or more topics or searching an information system at the same time. When processing multiple information tasks, priorities must be established as there are cognitive and physical limitations in processing multiple information tasks at once. The level of cognitive attention involved in multitasking behavior can vary depending on the complexity and importance of the information task. The objectives of this study are to understand: (a) the relationship between attention and information task prioritization behavior when people interact with information retrieval systems to find information for multiple tasks; (b) The effect of the degree of attention on information task prioritization behavior when people interact with an IR system to find information for multiple tasks. A review of the relevant literature shows that when people interact with information retrieval systems to find information for multiple tasks, their level of attention affects how they prioritize multiple information tasks. It should be noticed that people pay more attention to things they find interesting or important. Human-centered system design based on a conceptual understanding of multitasking is discussed.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.143-152
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• 2024

Due to COVID-19, domestic Duty-free shops have been severely impacted, and with the expansion of the untact market, the proportion of mobile shopping has increased. So far, mobile duty-free shop AR shopping is not active, and related research is scarce. Therefore, we aims to enhance Duty-free Shopping APPs with AR technology by researching the needs of foreign users. First, in the mobile duty-free shop app, the AR shopping interface must be in a prominent position to be open and easy to use. Second, there should be an explanation or help for location and function so that all users can easily recognize the AR shopping interface. Third, when wearing duty-free items in the AR shopping interface or adding them to the storage and shopping cart of interest, the interface must be simple and flexible, making it convenient to use and operate. Fourth, technical improvements must be made to prevent errors. We expect that the research will help develop AR shopping technology and domestic duty-free shop AR shopping technology and revitalize online and offline duty-free shops.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.539-549
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• 2024

This study employed text mining techniques like frequency analysis, word clouds, and LDA topic modeling to assess consumer satisfaction and dissatisfaction with Hyundai Motor Company in the Chinese market, compared to brands such as Toyota, Volkswagen, Buick, and Geely. Focusing on compact vehicles from these brands between 2021 and 2023, this study analyzed customer reviews. The results indicated Hyundai Avante's positive factors, including a long wheelbase. However, it also highlighted dissatisfaction aspects like Manipulate, engine performance, trunk space, chassis and suspension, safety features, quantity and brand of audio speakers, music membership service, separation band, screen reflection, CarLife, and map services. Addressing these issues could significantly enhance Hyundai's competitiveness in the Chinese market. Previous studies mainly focused on literature research and surveys, which only revealed consumer perceptions limited to the variables set by the researchers. This study, through text mining and comparing various car brands, aims to gain a deeper understanding of market trends and consumer preferences, providing useful information for marketing strategies of Hyundai and other brands in the Chinese market.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.11-18
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• 2024

The purpose of this study was to investigate the effects of an animal-mediated therapy program on children with developmental disabilities on social skills related to social-emotional development and learning, which are important in modern society. The subjects of the study were children with developmental disabilities at a special school, and the animal-mediated therapy program consisted of 12 sessions. The study was divided into experimental and control groups and conducted pre- and post-test by measurement items. SPSS 25.0 was used to analyze the data. First, children with developmental disabilities in the experimental group who participated in the animal-mediated therapy program showed a significant difference (z=-2.20, p<.05) in the overall social-emotional development compared to the control group, and statistically significant values were found in the subfactors of non-dependence on teachers, interaction with peers, and achievement motivation. Second, the experimental group who received animal-mediated therapy showed a significant effect (z=-2.20, p<.05) in all factors of learning-related social skills. In conclusion, animal-mediated therapy was found to have a positive effect on the social-emotional development and learning-related social skills of children with developmental disabilities. Based on the results of this study, it is recommended that more specific and systematic programs should be developed and applied to enhance the social-emotional development and learning-related social skills of children with developmental disabilities for a healthy life.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.307-317
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• 2024

The purpose of this study is to analyze the impact of merchants' perceptions of service quality, youth mall creation, and traditional market revitalization on management performance to derive factors that can improve the self-sustainability of the traditional market. In particular, it was intended to predict the practical effect of the youth mall creation project by including merchants' perceptions of the rapidly emerging youth mall to revitalize the traditional market. In this study, 430 small business owners from five private traditional markets in Iksan were surveyed, the research model was verified by analyzing the technical statistics, reliability, and validity of the data collected using the SPSS 21.0 program, and the hypothesis was verified through correlation and regression analysis. Although youth malls are actively promoted at the government level to revitalize traditional markets and improve management performance, this study confirmed that the creation of youth malls in traditional markets does not directly affect traditional market revitalization and management performance, confirming that policies to create youth malls that can actually help revitalize traditional markets and improve management performance in the future need to be promoted.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.183-192
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• 2024

The purpose of this study is to empirically analyze the determining factors (economy, security, domestic politics, administration, and international politics) that affect the ROK-US defense cost sharing decision. Through this, we will gain a deeper understanding of the defense cost sharing decision process and improve the efficiency of defense cost sharing calculation and execution. The scope of the study is ROK-US defense cost sharing from 1991 to 2021. The data used in the empirical analysis were various secondary data such as Ministry of National Defense, government statistical data, SIPRI, and media reports. As an empirical analysis method, multiple regression analysis using time series was used and the data was analyzed using an autoregressive model. As a result of empirical research through multiple regression analysis, we derived the following results. It was analyzed that the size of Korea's economy, that is, GDP, the previous year's defense cost share, and the number of U.S. troops stationed in Korea had a positive influence on the decision on defense cost sharing. This indicates that Korea's economic growth is a major factor influencing the increase in defense cost sharing, and that the gradual increase in the budget and the negotiation method of the Special Agreement (SMA) for cost sharing of stationing US troops in Korea play an important role. On the other hand, the political tendencies of the ruling party, North Korea's military threats, and China's defense budget were found to have no statistically significant influence on the decision to share defense costs.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.345-352
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• 2024

K-Pop Square Media, located at COEX in Samseong-dong, has gained public attention and mass media focus by showcasing various three-dimensional videos on a large LED display. The video content on the distinctive large curved LED display utilizes a form of media façade technique, establishing itself as a new landmark and attraction within the spatial characteristics of the COEX Plaza. This study aims to examine the characteristics of media facades used in outdoor advertising in urban spaces, focusing on K-Pop Square Media. The approach for this research involves three aspects: Firstly, examining the 'spatial characteristics' of urban public spaces by referencing Kevin Lynch's five elements constituting urban space and William J. Mitchell's exploration of smart spaces and changes in spatial paradigms. Secondly, analyzing the 'digital nature' of outdoor advertising through an examination of three types of Digital Out-Of-Home (DOOH) Media. Thirdly, exploring the 'technological advancements and content composition of media facades' by investigating types of display media (projection, LED screens), the inception of media facades, and the latest display technology like Anamorphic displays. Through this research, it becomes evident that K-Pop Square Media exhibits characteristics of publicness, communicativeness, artistry, and placemaking through the spatial characteristics of smart spaces, the media-specific aspects of Digital Out-Of-Home advertising, and the content composition of media facades.

• The Journal of the Convergence on Culture Technology
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• v.10 no.3
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• pp.413-420
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• 2024

After Friedrich Nietzsche's advocacy of nihilism, many literary works, dramas, and films have depicted aspects of human psychology associated with nihilism. Animation, too, has been used to convey nihilism, with narratives infused with nihilistic themes produced as both TV series and theatrical animations. Particularly, animation, as a visual medium capable of realizing any imaginative image unlike other media, possesses distinctive characteristics from live-action cinematography and differs from comics in its temporal properties. Hence, this study aims to analyze how Nietzsche's defined three stages of nihilism are represented within animation characters and how they construct various scenarios, using the anime "Attack on Titan" as a case study. The research unfolds by first examining Nietzsche's types of nihilism and the three stages through a review of literature, while also investigating the portrayal of nihilism in mass media and considering the unique attributes of animation. Secondly, building upon the literature review, the analysis interprets the narrative and constructed world of the chosen case study from a nihilistic perspective, examining four major characters through the stages of passive nihilism, active nihilism, and eternal recurrence. The findings demonstrate that the anime conveys two messages regarding negation and affirmation of one's life and existence, thereby offering viewers an opportunity to deeply contemplate human existence. This study is considered significant as it examines how Nietzschean nihilism is portrayed within the popular entertainment medium of animation.

• The Journal of the Convergence on Culture Technology
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• v.10 no.3
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• pp.7-11
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• 2024

The bedsore prevention cushion serves to prevent the skin on the buttocks of a wheelchair user from being damaged through friction with the wheelchair seat. This is because it absorbs some of the weight applied to the wheelchair seat and allows the weight to be applied evenly to the entire contact surface. For the impact test, which is part of the performance testing of bedsore prevention cushions, a hip model that represents the sitting posture of a wheelchair user is required. In this study, a hip model was manufactured for impact testing of bedsore prevention cushions for wheelchairs. Performance tests for pressure bedsore prevention cushions for wheelchairs include KSP 0236, a Korean standard, and KS P ISO 16840-2, an ISO international standard. The hip model proposed in KS P ISO 16840-2 was more suitable for impact testing of bedsore prevention cushions for wheelchairs. However, the guidelines for making hip models proposed by international standards need to be modified to reflect the advancement of model making technology and use easier methods. We propose a new hip model production method that produces a hip model out of plastic all at once and additionally attaches SS-41 steel plates processed into the shape of the hip to make the mass of the model similar to the human body.