• 제목/요약/키워드: ISO Regulation

검색결과 109건 처리시간 0.031초

Variability in the Viral Protein Linked to the Genome of Turnip Mosaic Virus Influences Interactions with eIF(iso)4Es in Brassica rapa

  • Li, Guoliang;Zhang, Shifan;Li, Fei;Zhang, Hui;Zhang, Shujiang;Zhao, Jianjun;Sun, Rifei
    • The Plant Pathology Journal
    • /
    • 제37권1호
    • /
    • pp.47-56
    • /
    • 2021
  • Plants protect against viruses through passive and active resistance mechanisms, and in most cases characterized thus far, natural recessive resistance to potyviruses has been mapped to mutations in the eukaryotic initiation factor eIF4E or eIF(iso)4E genes. Five eIF4E copies and three eIF(iso)4E copies were detected in Brassica rapa. The eIF4E and eIF(iso)4E genes could interact with turnip mosaic virus (TuMV) viral protein linked to the genome (VPg) to initiate virus translation. From the yeast two-hybrid system (Y2H) and bimolecular fluorescence complementation (BiFC) assays, the TuMV-CHN2/CHN3 VPgs could not interact with BraA.eIF4E.a/c or BraA.eIF(iso)4E.c, but they could interact with BraA.eIF(iso)4E.a in B. rapa. Further analysis indicated that the amino acid substitution L186F (nt T556C) in TuMV-UK1 VPg was important for the interaction networks between the TuMV VPg and eIF(iso)4E proteins. An interaction model of the BraA. eIF(iso)4E protein with TuMV VPg was constructed to infer the effect of the significant amino acids on the interaction of TuMV VPgs-eIF(iso)4Es, particularly whether the L186F in TuMV-UK1 VPg could change the structure of the TuMV-UK1 VPg protein, which may terminate the interaction of the BraA.eIF(iso)4E and TuMV VPg protein. This study provides new insights into the interactions between plant viruses and translation initiation factors to reveal the working of key amino acids.

ECE R51 자동차주행소음 규정의 개정에 따른 자동차 소음 평가 (Estimation of the Motor Vehicle Noise Emission based on Amendments of European Regulation R51)

  • 박진우;조상수;신재승
    • 한국소음진동공학회:학술대회논문집
    • /
    • 한국소음진동공학회 2007년도 추계학술대회논문집
    • /
    • pp.783-787
    • /
    • 2007
  • Nowadays, vehicle becoming necessity is increasing gradually and is main cause of environmental problem. The current automobile noise measurement test method such as ISO 362 which have been used many countries contribute seriously to enforce the regulation of the noise rigidly and actively study vehicle's noise, using that method. However, the amendment of ISO 362 was completed under the international agreement due to the changes in vehicle's techniques and road conditions. In this study, the difference between the current ISO 362(or ECE R51) and new ISO 362(or new ECE R51) is estimated by the test using the practical car producing domestically because the Korean manufacturer have to be interested in new test method.

  • PDF

Pass by Noise Test Site Variability

  • 김병삼
    • 한국공작기계학회논문집
    • /
    • 제14권3호
    • /
    • pp.116-121
    • /
    • 2005
  • The objective of this paper is to compare the site-to-site variability of ISO 10844 pass by the noise test sites. In order to investigate the site-to-site variance of test surfaces, European commercial tires are tested at seven different test sites. Three Korea test sites and four Europe test sites are selected. The pass by noise test is done according to a 2001/43/EC regulation. Although the ISO surface has a very specific track composition, it does not reduce the variation of pass by noise measurements over the surface of test sites. This paper shows that the test results of pass by noise level are different depending on the test sites. The correlation obtained in this work is able to predict the pass by noise level for certain test site using the data measured from another test site. The prediction value is range with an error within 1dB(A).

속응자원의 국내 및 북미 ISO/RTO 주파수조정예비력 서비스 제공에 따른 보상규칙 비교 분석 (Comparison of Compensation Rules for Fast Responding Resources Providing Frequency Regulation Service in Domestic and North American ISO/RTO Power Electricity Market)

  • 박대현;박용기;박종배;김발호;노재형
    • 전기학회논문지
    • /
    • 제67권5호
    • /
    • pp.617-625
    • /
    • 2018
  • Since FERC order 755 was published, each frequency regulation market rules of the North American ISO/RTO have been revised in many parts. In 2016, the domestic CBP market has also changed its market rules to allow ESS to participate in the frequency regulation reserve services(Governor Free and Automatic Generation Control). This paper compares and analyzes the changed North American ISP/RTO market and domestic CBP market rules. In particular, we compare PJM and CAISO frequency regulation market pricing mechanism and settlement rules with the settlement rules of the domestic CBP market and compare the factors of each market used to compensate the participating resources in terms of resource dependency and accuracy.

제조물 책임 면책 수단으로서의 ISO 26262와 ISO/PAS 21448 (ISO 26262 and ISO/PAS 21448 as Exemption Clauses of Product Liability)

  • 이성수
    • 전기전자학회논문지
    • /
    • 제23권1호
    • /
    • pp.346-349
    • /
    • 2019
  • 제조물 책임은 자동차 산업에서 매우 중요한 규제 요소로 작용하고 있으며, 이에 대한 면책 수단으로 제정된 것이 ISO 26262 국제 표준이다. 자율주행자동차에서는 제조물 책임의 중요성이 더욱 높아지기 때문에 추가로 ISO/PAS 21448이 제정되었으나, 이 역시 주로 센싱 단계에만 적용이 가능하기 때문에 제조물 책임을 어느 정도 면책시킬 수 있으나 완전한 면책은 어렵다. 이에 따라 자율주행자동차의 상용화를 위해서는 완전한 면책수단으로서 새로운 국제 표준이 개발될 때까지 한시적으로 법체계의 개선이 반드시 필요하다.

일회용 의료기기에 적용을 위한 ISO 14971:2019 분석과 Periodic Safety Update Report 작성 방법 - Medical Device Regulation 2017/745 요구사항 중심으로 (ISO14971:2019 Detailed Analysis and Periodic Safety Update Report Establishment Method for the Single Use Medical Device - Focusing on Medical Device Regulation 2017/745 requirements)

  • 박상민;류규하
    • 대한의용생체공학회:의공학회지
    • /
    • 제44권1호
    • /
    • pp.1-10
    • /
    • 2023
  • With the announcement of MEDICAL DEVICE REGULATION 2017/745 (MDR) on April 5 2017, medical device manufacturers shall apply ISO 14971:2019 (3rd) revised in December 2019. However, there is not much related information and guidance available to medical device manufacturers, especially single use medical device. Risk management process basically follow 5 steps which are Risk Analysis, Risk Evaluation, Risk Control, Evaluation of overall residual risk and post-production activities. The purpose of this study is to provide a guidance of from risk analysis with Failure Mode and Effects Analysis (FMEA) table to overall residual risk evaluation for the single use medical device and to reflect it in a Periodic Safety Update Reports (PSUR) to satisfy with MDR requirements with single use medical device which are widely used and manufactured FDA class 2 or CE class IIb as examples. For this study, single use medical device manufacturer can adopt ISO 14971:2019 in accordance with MDR requirements and it can be extended to the PSUR. But there are still limitations to adopt to the all-single use medical device especially high class, private device and implantable device. So, Competent Authority (CA) shall publish more guidance for the single use medical device.

선박 진동계측에 관한 국제 동향(ISO 20283) (Mechanical vibration-Measurements of vibration on ships(ISO 20283))

  • 이돈출;김재승
    • 한국소음진동공학회:학술대회논문집
    • /
    • 한국소음진동공학회 2007년도 춘계학술대회논문집
    • /
    • pp.550-555
    • /
    • 2007
  • This paper introduces the mechanical vibration-measurements of vibration on ships(ISO 20283). Regulations and guidelines for vibration of hull structures, propulsion machinery and onboard equipments on ship were established mainly by classification societies or International Association of Classification Societies(IACS). The initial draft of ISO 20283 was proposed by USA and based on US military standards. Though these are not suitable to passenger and merchant ships, many experts have felt the need of the ISO regulation for the vibration measurement on ship. Hence, these standards are re-drafted and reviewed by particulate ISO members. In this paper, authors introduce the important agendas and the controversial items during setup of ISO 20283.

  • PDF

ISO 37001의 효율적 운영을 위한 개선방안 연구 (A Study on the improving ways for effective operation of ISO 37001)

  • 전병호;김재영;강병구
    • 디지털산업정보학회논문지
    • /
    • 제16권3호
    • /
    • pp.73-82
    • /
    • 2020
  • 'ISO 37001 - Anti-bribery Management Systems, one of the Business Ethics of Global Standards, is a new standard to help organizations fight bribery and promote an ethical business culture which was developed in 2016. ISO 37001 can provide the tools and systems to greatly reduce the risk and help organizations deal with it effectively if it does arise. After enforcing the Improper Solicitation and Graft Act, Korean government standardized ISO 37001 harmonizing International Standards into Korean Industrial Standards (KS) in 2017. It is meaningful in that Korean companies have localized regulation which applies to global standard anti-bribery management systems. About 100 organizations have adopted ISO 37001 as in the first half of 2019. So far many side effects of other ISO certifications have been recognized. Therefore, it is necessary to investigate the current status of ISO 37001 in Korea for effective operation and management. The primary purpose of this paper is to investigate the current status and problems of ISO 37001 in Korea. It can provide useful guidelines for improving ISO 37001 to manage bribe and corruption effectively.

국내 물 자원 통계자료 분석을 통한 물발자국 방법론 국내 적용 가능성 확인 연구 (A Study on the Applicability of Water Footprint Methodology in Korea by Analyzing Domestic Water Resources Statistics)

  • 김선욱;조서원;안재현;이한웅;연성모
    • 청정기술
    • /
    • 제24권2호
    • /
    • pp.146-153
    • /
    • 2018
  • 물발자국은 EU가 추진하고 있는 자원효율적인 유럽을 위한 로드맵(Roadmap to a Resource Efficient Europe)을 바탕으로 제시된 친환경제품 시장통합정책(Single Market for Green Product initiative)의 중요한 구성요소이다. 2014년 7월 EU 회원국의 주도로 물발자국 산정 국제표준(ISO 14046)이 제정되었으며 우리나라도 한국산업표준(KS I ISO 14046)으로 2015년 4월 부합화를 완료하였다. 국제표준(ISO 14046)에 기반을 둔 인증제도가 도입되는 경우, 기반을 갖추지 못한 인도, 베트남 등의 개도국에게는 수출시 무역장벽이 될 수 있으므로 우리나라는 이를 역이용하기 위한 전략을 수립해야 한다. 한편, 물발자국은 전과정평가(LCA)를 적용한 유사 발자국(예, 탄소발자국)인증과 비교할 때 국지적(Local) 환경영향을 고려하도록 되어 있어, 우리나라에서 생산 및 제조되는 제품들은 우리나라 수역에 미치는 영향을 고려해야 한다. 따라서 물발자국 산정방법은 국내외 호환을 위해 표준에 적합해야 하며, 우리나라의 물 환경을 고려하기 위해서 우리나라 적합한 물발자국 산정계수들의 도출이 필요하다. 이를 위해 이 연구에서는 국제표준을 바탕으로, 현재 국내 외에서 진행된 물발자국 산정연구를 검토하고 국내 기존 물 자원 관련 통계자료 분석을 통해 물발자국 방법론의 국내 적용 가능성을 확인하였다.

ISO규정에 의한 선박의 선내진동과 승선근무 환경평가 (An Evaluation of Working Environment of the Ship Vibration by ISO Regulation)

  • 유영훈
    • 해양환경안전학회:학술대회논문집
    • /
    • 해양환경안전학회 2007년도 추계학술발표회
    • /
    • pp.139-144
    • /
    • 2007
  • 선박에서 발생하는 진동은 여객의 안락감을 결정하거나 승조원의 근무환경에 미치는 영향이 크므로 매우 중요하다 선박에서 발생하는 진동은 선박의 속도를 좌우하는 추진방식의 발달과 가장 밀접한 관계가 있다. 이와 같이 추진력을 발생하기위하여 선박의 기관실에는 디젤엔진의 연속적인 폭발과정에서 기인하는 강력한 진동이 발생하게 된다. 진동이 인체에 미치는 피해는 생리적인 피해와 심리적인 피해로 발생하게 된다. 진동 환경에 인체가 노출되는 경우, 선내의 진동에 대한 평가는 국제표준화지침인 ISO 6954:2000(E)에 의해 정하고 있다. 본 연구에서는 선박에서 진동이 인체에 미칠 수 있는 영향을 평가하기위해 ISO 6954:2000(E)에서 규정하는 지침에 의해 선박진동의 영향이 가장 큰 기관실, 기관제어실, 각종선설 및 브리지 등에서 발생하는 진동의 크기를 측정 비교하여 평가한다.

  • PDF