• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3687-3690
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• 2014

MicroRNA 200c is a microRNA 200 family member that plays an important role in regulation of the epithelial-to-mesenchymal transition (EMT). The prognostic value of microRNA 200c in solid tumors remains controversial because of inconsistent data. Here, we report a meta-analysis of the association of microRNA 200c expression and survival in patients with solid tumors. Pubmed was searched up to November 2013 for studies investigating microRNA 200c expression and overall survival (OS) in solid tumors. Hazard ratios (HRs) with 95% confidence intervals (CIs) for OS were extracted from each study. Pooled HR and CIs were calculated using the Mantel-Haenszel fixed-effects models. A total of five studies evaluating colorectal cancer, gastric cancer, ovarian cancer, pancreatic cancer and endometrial cancer were included in the analysis. Data were divided into tissue microRNA 200c expression group and serum microRNA 200c expression group. The combined HRs [95%CIs] estimated for OS were 0.62 [0.42-0.91] and 2.16 [1.32-3.52] respectively. Low expression of microRNA 200c in tumor tissue and high expression of microRNA 200c in serum are associated with worse survival in solid tumors. Further study is needed to elucidate this contradiction.

• Journal of Advanced Marine Engineering and Technology
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• v.37 no.2
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• pp.170-177
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• 2013

This study is focused on the shape design and flow analysis on a 200 W-class Gyromill type vertical axis wind turbine rotor blade. Single tube theory is adopted for the shape design of the turbine blade. 2-dimensional CFD analysis is conducted to examine the turbine performance with basic shape, and then 3-dimensional shape is determined from the examination of the performance. By the CFD analysis on the 3-dimensional shape of the wind turbine, performance of the turbine is examined and also, shape of the wind turbine rotor blade is determined accordingly. From the results of this study, a 200 W-class Gyromill type vertical axis wind turbine rotor blade is designed and the reliability of the design method is confirmed by CFD analysis.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.12 no.11
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• pp.882-889
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• 2002

This paper presents vibration control performance of a squeeze mode ER mount for high static load. After experimentally investigating the field-dependent damping force under the squeeze mode motion, a squeeze mode ER mount which can support 200 kg of static load is designed and manufactured. Displacement transmissibility of the proposed ER mount is experimentally evaluated in frequency domain with respect to the intensity of the electric field, and a sky-hook control algorithm is designed to attenuate unwanted vibration. Vibration isolation capabilities of the flow mode ER mount and rubber mount are compared to those of the proposed squeeze mode ER mount.

• Molecules and Cells
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• v.42 no.6
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• pp.495-500
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• 2019

Brain cytoplasmic 200 RNA (BC200 RNA), originally identified as a neuron-specific non-coding RNA, is also observed in various cancer cells that originate from non-neural cells. Studies have revealed diverse functions of BC200 RNA in cancer cells. Accordingly, we hypothesized that BC200 RNA might be modified in cancer cells to generate cancerous BC200 RNA responsible for its cancer-specific functions. Here, we report that BC200 RNA sequences are highly heterogeneous in cancer cells by virtue of multiple adenine nucleotide insertions in the internal A-rich region. The insertion of adenine nucleotides enhances BC200 RNA-mediated translation inhibition, possibly by increasing the binding affinity of BC200 RNA for eIF4A (eukaryotic translation initiation factor 4A).

• Magazine of the Korean Society of Agricultural Engineers
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• v.12 no.1
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• pp.1854-1860
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• 1970

Results of this study on the influence of percent passing of No. 200 sieve on soil compaction are as follows; 1. The higher maximum dry density of soil is, the lower optimum moisture content is. Maximum dry density is highest value and optimum moisture content is the lowest value in twocases that percents of No. 200 sieve are 30% in soils of which percents retained on No. 10 sieve are 5% and 10% respectively. 2. Maximum dry density increases according as uniformity coefficient increase. Maximum dry density is the highest when uniformity coefficient is approximately 300 in soil of which maximum diameter is 4.76mm. 3. Maximum dry density has a tendency to become large according as value of Cu Caincrease. Correlation between maximum dry density and $Log_{10}$(CuCa) shows straight line. 4. Maximum dry density increases according as n increase and reaches the peak when n equal 0.35 in condition that the index of talbot formula n is less than 0.35 in soil of which maximum diameter is 4.76mm. 5. Maximum dry density has a tendency to increase according as value of Cg $(Cg=\frac{P_{50}^2}{P_{10}{\times}{P_{200}}$) decrease.

• Journal of Ocean Engineering and Technology
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• v.27 no.6
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• pp.65-72
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• 2013

This paper describes a finite element analysis (FEA) of the body frame of a subsea robot, Crabster200 (CR200). CR200 has six legs for mobility instead of screw type propellers, which distinguishes it from previous underwater robots such as remotely operated vehicles (ROVs) and autonomous underwater vehicles (AUVs). Another distinguishing characteristic is the body frame, which is made of carbon fiber reinforced plastic (CFRP). This body frame is designed as a rib cage structure in order to disperse the applied external loads and reduce the weight. The frame should be strong enough to support many devices for exploration and operation underwater. For a reasonable FEA, we carried out specimen tests. Using the obtained material properties, we performed a modal analysis and FEA for CR200 with a ready posture. Finally, this paper presents the FEA results for the CFRP body frame and the compares the characteristics of CFRP with conventional material, aluminum.

• The Korean Journal of Financial Management
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• v.24 no.2
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• pp.41-79
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• 2007

This study examines the expiration-day effects of stock index futures and options in the Korean stock market. The so-called 'expiration-day effects', which are the abnormal stock price movements on derivatives expiration days, arise mainly from cash settlement. Index arbitragers have to bear the risk of their positions unless they liquidate their index stocks on the expiration day. If many arbitragers execute large buy or sell orders on the expiration day, abnormal trading volumes are likely to be observed. If a lot of arbitragers unwind positions in the same direction, temporary trading imbalances induce abnormal stock market volatility. By contrast, if some information arrives at market, the abnormal trading activity must be considered a normal process of price discovery. Stoll and Whaley(1987) investigated the aggregate price and volume effects of the S&P 500 index on the expiration day. In a related study, Stoll and Whaley(1990) found a similarity between the price behavior of stocks that are subject to program trading and of the stocks that are not. Thus far, there have been few studies about the expiration-day effects in the Korean stock market. While previous Korean studies use the KOSPI 200 index data, we analyze the price and trading volume behavior of individual stocks as well as the index. Analyzing individual stocks is important for two reasons. First, stock index is a market average. Consequently, it cannot reflect the behavior of many individual stocks. For example, if the expiration-day effects are mainly related to a specific group, it cannot be said that the expiration of derivatives itself destabilizes the stock market. Analyzing individual stocks enables us to investigate the scope of the expiration-day effects. Second, we can find the relationship between the firm characteristics and the expiration-day effects. For example, if the expiration-day effects exist in large stocks not belonging to the KOSPI 200 index, program trading may not be related to the expiration-day effects. The examination of individual stocks has led us to the cause of the expiration-day effects. Using the intraday data during the period May 3, 1996 through December 30, 2003, we first examine the price and volume effects of the KOSPI 200 and NON-KOSPI 200 index following the Stoll and Whaley(1987) methodology. We calculate the NON-KOSPI 200 index by using the returns and market capitalization of the KOSPI and KOSPI 200 index. In individual stocks, we divide KOSPI 200 stocks by size into three groups and match NON-KOSPI 200 stocks with KOSPI 200 stocks having the closest firm characteristics. We compare KOSPI 200 stocks with NON-KOSPI 200 stocks. To test whether the expiration-day effects are related to order imbalances or new information, we check price reversals on the next day. Finally, we perform a cross-sectional regression analysis to elaborate on the impact of the firm characteristics on price reversals. The main results seem to support the expiration-day effects, especially on stock index futures expiration days. The price behavior of stocks that are subject to program trading is shown to have price effects, abnormal return volatility, and large volumes during the last half hour of trading on the expiration day. Return reversals are also found in the KOSPI 200 index and stocks. However, there is no evidence of abnormal trading volume, or price reversals in the NON-KOSPI 200 index and stocks. The expiration-day effects are proportional to the size of stocks and the nearness to the settlement time. Since program trading is often said to be concentrated in high capitalization stocks, these results imply that the expiration-day effects seem to be associated with program trading and the settlement price determination procedure. In summary, the expiration-day effects in the Korean stock market do not exist in all stocks, but in large capitalization stocks belonging to the KOSPI 200 index. Additionally, the expiration-day effects in the Korean stock market are generally due, not to information, but to trading imbalances.

• Journal of the Korean Society for Railway
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• v.8 no.3
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• pp.222-227
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• 2005

This study investigates the change of the temperature and mechanical properties of the braking disk for the railway vehicle. The average temperature is measured about $100^{\circ}C$ and the maximum temperature is measured over $200^{\circ}C$ by non-contact sensor from Seoul to Chun-an. As a result of measuring, we determine the temperature of test(tensile and J-integral) at $20^{\circ}C,\;100^{\circ}C,\;200^{\circ}C$ and $300^{\circ}C$. In the test, the material values are decreased by the increasing of the temperature. But ratio of decreasing is the largest at $200^{\circ}C$, the tensile test value is decreased about $10\%$ and the J-integral test value is decreased $30\%$. The mechanical properties of this material are mostly changed at $200^{\circ}C$.

• Journal of Korean Association for Spatial Structures
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• v.19 no.2
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• pp.51-61
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• 2019

The objective of this study is to analysis the seismic response of 200m spanned honeycomb lattice domes under horizontal and up-down ground motion of El Centro earthquake. For the analysis of seismic response of the honeycomb lattice domes by rise/span ratio, the time history analysis is used for the estimation of the dynamic response. The low rise lattice dome is less deformed and less stressed than the high rise lattice dome for the earthquake ground motion. The 3-dimensional earthquake response is not significantly different the dynamic response of one directional ground motion. The earthquake response of domes with LRB isolation system is significantly reduced for the asymmetric vertical deformation and the horizontal and vertical accelerations.

• Journal of international Conference on Electrical Machines and Systems
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• v.3 no.4
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• pp.389-393
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• 2014

This paper presents one of the methods for design to reduce the noise and vibration of 200kW motor for electric propulsion ship. One of the important factors affecting vibration of the motor is the resonance. The natural frequency and natural mode of the 200kW motor is analyzed by using FEM tool and impact test equipment to avoid the resonance. Also, compare FEM result with impact test result to make a reliable FE model of 200kW motor. In order to find out the effect of the noise and vibration of the motor by electromagnetic excitation force, conduct electromagnetic-structure coupled analysis. These characteristics are much useful to design 200kW motor for electric propulsion ship.