• Proceedings of the Safety Management and Science Conference
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• 2006.04a
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• pp.309-313
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• 2006

본 연구는 한국산업안전공단에서 구축한 종합위험관리체제(IRMS)의 추진경과, 운영조직체계, IRMS 효과, 개선사항 및 향후 발전방향 등 IRMS 사업의 전 분야를 재검토하여 문제점에 대한 개선방안과 중 장기 발전방안을 제시하고자 하였다. 이를 위해 IRMS가 구축된 PSM 사업장에 대하여 설문조사를 실시하여 IRMS 효과를 분석하여 문제점을 도출하고, 이를 바탕으로 교육, 조직, 정보공유, 전산화, 기타 부문에서 개선방안을 제시하였다. 또한 선진국의 안전관리 실태를 전망하고, 이를 통하여 IRMS 중 장기 발전방안 수립을 위한 추진방향을 제시하였다.

• Economic and Environmental Geology
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• v.40 no.5
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• pp.699-703
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• 2007

Compound-specific isotope analysis (CSIA) by isotope ratio mass spectrometer (IRMS) interfaced with gas chromatography (GC) is a state of the art analytical technique for stable isotopes in earth sciences, environmental sciences and forensics. Since early 1990s, GC-IRMS has been widely used to investigate the authenticity of food in forensic science and to trace the sources of organic contaminants in environmental science. In Korea, a GC-IRMS was firstly installed at the Korea Basic Science Institute (KBSI) in early 2005. In this study, we introduce the GC-IRMS of the KBSI shortly to stimulate various isotope-related researches of Korea, and report preliminary CSIA results for BTEX of different manufacturers.

• Proceedings of the KSEEG Conference
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• 2007.04a
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• pp.444-446
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• 2007

• Mass Spectrometry Letters
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• v.2 no.2
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• pp.33-36
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• 2011

The misuse of anabolic androgenic steroids is of particular concern in sports and society. Thus, it is of great importance to discriminate endogenous steroids such as testosterone or testosterone prohormones from their chemically identical synthetic copies. In this study, gas chromatography-combustion/isotope ratio mass spectrometric (GC-C/IRMS) method has been developed and validated for discriminating the origin of anabolic androgenic steroids. The method involves the solid-phase extraction, enzymatic hydrolysis with ${\beta}$-glucuronidase, HPLC-fractionation for the cleanup and analysis by GC-C/IRMS. The difference(${\Delta}^{13}C$) of urinary ${\delta}^{13}C$ values between synthetic analogues and endogenous reference compounds (ERC) by GC-C/IRMS was used to elucidate the origin of steroids, and intra- and inter-day precision, specificity and isotope fractionation were evaluated. The present GC-C/IRMS method combined with HPLC cleanup was accurate and reproducible enough to be successfully applied to the test of urine sample from suspected anabolic steroid abusers.

• Journal of the Korean Society of Safety
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• v.18 no.3
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• pp.88-93
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• 2003

The Process Safety Management (PSM) by the Law of Industry, Safety and Health has been performed for preventing major accidents of chemical plants since 1996. In terms of preventing chemical accidents more precisely, it is essential to develop a tool for quantitative risk assessment. For this, KOSHA (Korea Occupational Safety and Health Agency) developed an Integrated Risk Management System (IRMS). The system is designed to assimilate data on chemical plant hazards from external database, to integrate these data with location information(topographic and demographic), and to make them user-friendly accessible. The system consists of several main functions: display of five major Korean petrochemical complex layout display of equipment layout with its information utilizing the external database, zonation of the hazard effected area with consequence analyses, the most probable accident scenario generation, accident/incident database and calculation of frequency of accident using equipment reliability database, etc. The highlight of IRMS is to provide the risk contours using GIS(Geographical Information System) technology. IRMS is intended to manage hazardous installation more systematically and effectively, to reduce the number of accident remarkably, further minimizing production loss in the plant. The system is now under application to about 500 PSM sites as well as and emergency authorities in Korea by KOSHA (Korea Occupational Safety and Health Agency)

• 방재와보험
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• s.99
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• pp.19-23
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• 2003

• 방재와보험
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• s.82
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• pp.23-27
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• 1999

• Environmental Mutagens and Carcinogens
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• v.26 no.2
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• pp.45-47
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• 2006

The reactive oxygen species (ROS) caused the damage of macro molecules, many degenerative disease and cancer, which was produced in process of the aerotropic metabolic pathway as well as in response to the various genotoxic stresses. Recently, redox systems including the number of antioxidant proteins such as catalase, glutathione peroxidase, heam-containing peroxidase, peroxiredoxin and superoxide dismutase (SOD) has been reported to have chemopreventive effects. Antioxidant proteins has been known to have the activity directly removing ROS and affecting the protein-protein interaction and cell signaling to induce the cellular responses. We need to understand the mechanism of antioxidants prevent DNA damage from oxidative stresses for researching the cancer prevention and providing the development of cancer therapeutic drug.

• Proceedings of the Korean Institute of Industrial Safety Conference
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• 2003.10a
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• pp.48-53
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• 2003

화학산업의 공정안전 및 손실방지분야에서 정의하는 위험관리(Risk Management)란 공정 내에서 잠재적 위험요소를 찾아내어 예상되는 피해의 크기를 결정하고, 현재의 공정시스템의 능력과 안전장치의 적절성을 확인하며 이 위험요소를 예방하고 제어하기 위한 절차를 평가 관리하는 것이다.(중략)

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.12
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• pp.1503-1510
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• 2012

This paper presents an Integrated Risk Management System (IRMS), which is designed to integrate longitudinal and lateral collision avoidance systems. Indices representing longitudinal and lateral collision risks are designed. From the designed indices, an integrated control strategy is designed. A collision avoidance algorithm is designed to assist the driver in avoiding collisions by using a vehicle-driver-controller integrated linear model. The performance of the proposed algorithm is investigated via computer simulations conducted using the vehicle dynamics software CARSIM and Matlab/Simulink.