• Title/Summary/Keyword: IOR

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Effects of Silk Fibroin in Oxdative Stress and Membrane Fluidity in the Liver of SD Rats (Rat 간장의 산화적 스트레스 및 세포막 유동성에 미치는 실크 피브로인의 영향)

  • 최진호;김대익;박수현;김동우;이광길;여주홍;김정민;이용우
    • Journal of Sericultural and Entomological Science
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    • v.42 no.1
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    • pp.58-64
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    • 2000
  • This study was designed to investigate the effects of silk fibroin powder (Mw 500) on oxidative stress and membrane fluidity in liver membranes of rats. Sprague-Dawley (SD) male rats (160$\pm$10g) were fed basic diet (control group), and experimental diets (SEP-2.5 and SFP-5.0 groups) added 2.5 and 5.0 g/kg BW/day for 6 weeks. Cholesterol levels resulted in a significant decrease (12.1% and 9.0%, respectively) in the liver mitochondria and microsomes of SEP-5.0 group compared with control group. Membrane fluidity as significantly increased (16.1% and 16.5%, 5.8% and 17.4%) in the liver mitochondria and microsomes were significantly inhibited (16.1% and 18.3%, 8.1% and 15.1%, respectively) at the SFP-2.5 and SEP-5.0 groups compared with control group. Induced oxygen radicals (BOR) in liver mitochondria and microsomes were significantly inhibited (16.1% and 18.3%, 8.1% and 15.1%, respectively) at the SFP-2.5 and SEP-5.0 groups compared with control group. Induced oxygen radicals (IOR) in liver microsomes were significantly inhibited (17.0% and 26.6%, respectively) at the SFP-2.5 and SFP-5.0 groups compared with control group, but IOR in liver mitochondria was significantly inhibited about 12.3% at the SWP-400 group only compared with control group. Lipid peroxide (LPO) levels were significantly decreased (8.3% and 18.0%, 13.4% and 18.4%, respectively) in the liver mitochondria and microsomes of SFP-2.5 and SFP-5.0 groups compared with control group. Oxidized protein (OP) levels were dose-dependently decreased (5.4% and 11.6%, 19.0% and 24.4%, respaectively) in the iver mitochondria and microsomes of SFP-2.5 and SFP-5.0 groups compared with control group. These results suggest that administration of SFP may play an effective role in attenuating an oxidative stress and increasing a membrane fluidity in liver membranes.

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Effects of Sea Tangle (Laminaria japonica) and Fucoidan Components on the Attack of Oxygen Radicals in Kidney (신장의 활성산소 공격에 대한 다시마(Laminaria japonica)와 후코이단 성분의 영향)

  • CHOI Jin-Ho;KIM Dae-Ik;PARK Soo-Hyun;KIM Dong-Woo;KOO Jae-Geun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.6
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    • pp.758-763
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    • 1999
  • The protective effects of sea tangle (Laminaria japonica) extract and fucoidan components on the attack of oxygen radicals in kidney were studied, Sprague-Dawley (SD) male rats (210 $\pm$ 5 g) were with fed experimental diets of Dasi-Ex group (sea tangle extract powder of $4.0\%$ added to control diet), Euco-I, II and III groups (fucoidan powder of 1, 2 and $3\%$, respectively, added to Dasi-Ex group) for 45 days, Hydroxyl radical formations were significantly decreased ($10\~15\%$ and $15\~30\%$) in mitochondria and microsomes of Dasi-Ex and Fuco-I, II, III groups compared with control group. Hydrogen peroxide formations were also significantly decreased ($10\~15\%$) in microsomes of Dasi-Ex and Fuco-I, II, III groups compared with control group. Significant differences in mitochondrial basal oxygen radical (BOR) and microsomal induced oxygen radical (IOR) formations of Dasi-Ex and Fuco-I groups could not be obtained, but mitochondrial BOR and microsomal IOR formations were significantly decreased ($12\~15\%$ and $13\~14\%$) in Fuco-II and III groups compared with control group. BOR formations were significantly decreased ($12\~25\%$) in microsomes of Dasi-Ex and Fuco-I, II, III groups, and IOR formations were also significantly decreased ($10\~15\%$) in mitochondria of Fuco-I, II, III groups compared with control group, Significant differences in mitochondrial Mn-SOD activities of Dasi-Ex group could not be obtained, but mitochondrial Mn-SOD activities were dose-dependently increased by $8\%,\;16\%$ and $36\%$ in Fuco-I, II and III groups compared with control group, Mn-SOD activities an microsome were significantly increased about $20\%$ in Dasi-Ex group, while they were remarkably increased about $40\%$ in Fuco-I, II and III groups compared with control group. lipid peroxide contents were significantly decreased about $15\%$ and $15\~25\%$ in mitochondria and microsomes of Fuco-II and III groups. Membrane fluidities resulted in marked increases ($20\~35\%$ and $17\~24\%$) in mitochondria and microsomes of Dasi-Ex and Fuco-I, II and III groups. These results suggest that administrations of fucoidan added to sea tangle may play a pivotal role in attenuating attack of oxygen radicals in kidney.

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구개부에 발생한 Pleomorpic Adenoma의 문헌고찰 및 그 일예

  • Lee, Sang-Chull;Kim, Yeo-Gap;Choi, In;Jang, Kun-Taek
    • The Journal of the Korean dental association
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    • v.18 no.3 s.132
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    • pp.191-196
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    • 1980
  • The authors had observed a case of pleomorphic adenoma occurred on the right poster ior region of the palate of 29 year old man. The pleomorphic adenoma was enucleated by means of total resection of tumor mass including overlying oral mucasa with ulcerative area. The euncleated tumor mass was about 2.5cm in diameter and the postoperative prognosis was good.

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Effects of Silk Fibron on Oxidative Stress and Membrane Fluidity in Brain of SD Rats (뇌조직의 산화적 스트레스 및 세포막 유동성에 미치는 실크 피브로인의 영향)

  • 최진호;김대익;박수현;김정민;이종수;이광길;여주홍;이용우
    • Journal of Life Science
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    • v.10 no.5
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    • pp.511-518
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    • 2000
  • This study was designed to investigate the effects of silk fibroin powder (SFP : Mw 500) on oxidative stress and membrane fluidity in brain membranes of rats. Sprague-Dawley (SD) male rats (160$\pm$10 g) were fed basic diet (control group), and experimental diets (SFP-2.5 and SFP-5.0 groups) added 2.5 and 5.0 g/kg BW/day for 6 weeks. Cholesterol level was significantly decreased about 8.0% in brain microsomes of SFP-5.0 group only compared with control group. Membrane fluidities were significantly increased (12.9% and 15.2%, respectively) in brain microsomes of SFP-2.5 and SFP-5.0 groups, but significant difference between in brain mitochondria of these two groups could be not obtained. Basal oxygen radicals (BOR) in brain mitochondria and microsomes were significantly ingibited (10.4%, and 24.0%, 7.9% and 14.9%, respectively) by SFP-2.5 and SFP-5.0 groups compared with control group. Induced oxygen radicals (IOR) in brain mitochondria and microsomes were significantly inhibited (11.8% and 14.1%, respectively) by SFP-5.0 groups compared with control group compared with control group. Lipid peroxide (LPO) levels were dose-dependently decreased (12.9% and 21.9%, 13.2% and 22.5%, respectively) in brain mitochondria and microsomes of SFP-2.5 and SFP-5.0 groups compared with control group. Oxidized protein (OP) levels were significantly decreased (15.7% and 17.1%, 16.7% and 15.7%, respectively) in brain mitochondria and microsomes of SFP-2.5 and SFP-2.5 and SFP-5.0 groups compared with control group. These results suggest that administration of SFP may play an effective role in a attenuating a oxidative stress and increasing a membrane fluidity in brain membranes.

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Governance Structure for Knowledge Transfer in Global Business Process Outsourcing (글로벌 프로세스 소싱에서의 효과적인 지식이전을 위한 거버넌스 구조 연구)

  • Kim, Gyeung-Min
    • Information Systems Review
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    • v.9 no.2
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    • pp.1-14
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    • 2007
  • The structure chosen to govern knowledge transfer in Inter Organizational Relationship(IOR) is often argued to be critical to the success of IOR. However, little research is done on the effective governance structure for knowledge transfer in global Business Process Outsourcing(BPO). The objective of this study is to explore the effective governance structure for knowledge transfer in IT intensive global BPO. Ground theory building methodology is used for this study. First, a generic framework on governance structure for knowledge transfer is derived from extant literature. The framework consists of potentially important constructs to study the governance mechanism for knowledge transfer. For the governance mechanism, this study focused on hierarchy/market structure, formal/informal control mechanisms and information systems. For knowledge type, the study focuses on sensitive knowledge, codifiable knowledge and non codifiable knowledge. This framework is applied to case analyses of two firms to explore effective governance mechanism to transfer each type of knowledge. As results of this study, pertinent propositions for future academic inquiry are derived.

Effects of Sea Tangle (Laminaria japonica) Extract and Fucoidan Drinks on Oxygen Radicals and Their Scavenger Enzymes in Stressed Mouse (스트레스 부하 마우스의 활성산소 및 제거효소에 미치는 다시마(Laminaria japonica)와 후코이단 음료의 영향)

  • CHOI Jin-Ho;KIM Dae-Ik;PARK Soo-Hyun;KIM Dong-Woo;KIM Chang Mok;KOO Jae Geun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.6
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    • pp.764-769
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    • 1999
  • This study was designed to investigate the effects of sea tangle (Laminaria japonica) extract (Dasi-Ex group: dry base $4.0\%$) and fucoidan-added (Fuco-I, II, III group: fucoidan of $1,0\%,\;2.0\%,\;3.0\%$ added to Dasi-Ex) drinks on the formation of oxygen radicals and scavenger enzyme activities of stressed mice. ICR male mice (20 $\pm$2 g) were fed experimental diets and these drinks instead of water for 18 days including 4 days of sociopsychological stress. Dasi-Ex and Fuco-I, II and III groups resulted in a marked decreases $20\~40\%$ in basal oxygen radical (BOR) formation, and $15\~25\%$ in induced oxygen radical (IOR) formation compared with control group. Hydroxyl radical formations were significantly inhibited about $10\%$ in Dasi-Ex group, while remarkably inhibited $30\~40\%$ in Fuco-I, II and III groups. lipid peroxide (ISO) levels in Dasi-Ex group were not significantly different from those of control group, tut Fuco-I, II and III groups resulted in a significant decreases about $10\%$ in LPO levels compared with control group, Dasi-Ex, Fuco-I, II and III groups resulted in a marked decreases ($31\%,\;36\%,\;39\%$ and $42\%$, respectively) in oxidized protein levels through production of carbonyl group. Significant differences in nitric oxide (NO) levels in Dasi-Ex group were not obtained, but NO levels were slightly inhibited about $7\%$ in Fuco-I and II groups and $20\%$ in Fuco-III group compared with control group. Significant differences in superoxide dismutase (SOD) and catalase (CAT) activities in Dasi-Ex and Fuco-I groups were not obtained, but Fuco-II and III groups resulted in a significant increases $25\~40\%$ in SOD activities, and about $10\%$ in CAT activities compared with control group. These results suggest that the sociopsychological stress and aging process could be effectively inhibited by biological activity of sea tangle and fucoidan components.

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The effect of Inhibition of Return on the spatial location of Focused-Attention (초점 주의의 공간 위치가 회귀억제에 미치는 영향)

  • 박찬희;심혜영;홍철운;김남균
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 2001.05a
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    • pp.293-297
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    • 2001
  • 본 연구는 공간상에서 초점 주의의 공간 위치가 인간의 감각 운동 협응에 의한 회귀억제에 미치는 영향을 정량적으로 분석하기 위하여 수행되었다. 본 실험은 20∼25세 나이의 성인 남·여를 대상으로 하였고, 자체 제작한 방음 암실에서 실시되었다. 지금까지의 회귀억제는 위치와 시간에 관련된 특이한 현상이라고 정의되어 왔다. 그러나 본 실험에서는 피험자의 주의가 집중되어 있는 공간에서는 시간에 관계없이 일어나지 않지만 피험자의 주의가 분산되었을 경우는 한 번 집중된 공간으로 주의를 옮기기가 어려운 회귀억제 현상이 일어났다. 본 연구에서는 회귀억제는 조건에 따라서는 자극 제시 간격(SOA)과 무관하며 초짐 주의 공간 위치와 관련된 현상임을 정량적으로 평가하였다.

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Estimate for Ensuring sight Distance of Curve Section from Consideration of the Environmental Impact Assessment based on the 3D GIS (환경영향을 고려한 곡선부 시거 안정성 분석을 위한 3차원 GIS 적용)

  • Choi Hyun;Han Sung-Dae;Lee Yong-Hee;Kang In-Joon
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2006.04a
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    • pp.431-436
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    • 2006
  • The latest system of GIS has been changing from 2 dimension to 3 dimension. According to the rapid growth of the fields linked to 3D GIS, 3D GIS has variously affected the public field, the national defense field, and the industrial field. This study estimated sight distance safety of curve section considering the environmental impact based on 3D GIS. Sight distance is calculated from the relation between road which keeps the three-dimension character and driver gaze, so it needs to consider both plane and vertical ior the accurate measuring. This study made analysis of the sight distance through considering the environmental impact with driving simulation of design speed 80km/h and running speed 60-120km/h.

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A Study on the Model of Sulfidation Kinetics Using Seashell Wastes (패각 폐기물을 이용한 황화반응 모델에 관한 연구)

  • Kim Young-Sik
    • Journal of Environmental Health Sciences
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    • v.30 no.5 s.81
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    • pp.395-401
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    • 2004
  • In this study, lots of methods have been studing to utilize energy and decrease contaminated effluents. There has been great progress on IGCC (Integrated gasification combined cycle) to reduce thermal energy losses. The following results have been conducted from desulfurization experiments using waste shell to remove $H_{2}S$. Unreacted core model ior desulfuriration rate prediction of sorbent was indicated. These were linear relationship between time and conversion. So co-current diffusion resistance was conducted reaction rate controlling step. The sulfidation rate is likely to be controlled primarily by countercurrent diffusion through the product layer of calcium sulfide(CaS) formed. Maximum desulfurization capacity was observed at 0.631 mm for lime, oyster and hard-shelled mussel. The kinetics of the sorption of $H_{2}S$ by CaO is sensitive to the reaction temperature and particle size at $800^{\circ}C$, and the reaction rate of oyster was faster than the calcined limestone at $700^{\circ}C$.

Design and Implementation of a Java ORB (Java ORB설계 및 구현)

  • Lee, Gwon-Il;Seo, Rae-Won
    • The Journal of Engineering Research
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    • v.6 no.1
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    • pp.41-51
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    • 2004
  • 본 논문은 OMG(Object Management Group) CORBA(Common Object Request Broker Architecture) 2.0을 만족하는 객체 중개자인 iORB(Internet ORB)의 설계 및 구현에 대한 것이다. iORB는 OMG IDL(Interface Definition Language)을 자바(Java)로 사상(mapping)할 뿐만 아니라 iORB 자체를 자바로 구현한 자바 객체 중개자(Java ORB)이다. iORB는 이식성 있는 스텁과 스켈리턴 코드를 지원하며, 기본 통신 프로토콜로 IIOP(Internet Inter-ORB Protocol)을 채택하고 있다. 그리고 원격 시스템의 객체 구현(object implementation) 참조에 필요한 IOR(Interoperable Object Reference) 찾기를 IP Multicast를 사용하고 있다. 본 논문에서는 이러한 특성을 지닌iORB의 설계 및 구현 경험에 대해서 기술한다.

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