• Nutritional Sciences
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• v.8 no.2
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• pp.125-132
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• 2005

According to Sa-Sang constitution, people can be classified into 4 types, Tae-Yang-In, Tae-Eum-In, So-Yang-In, and So-Eum-In. 1he purpose of this study was to examine any significance between types of Sa-Sang constitution and dietary factors. Physical and constitutional examinations as well as a questionnaire survey were conducted on a group of 483 college students. Among the group of 483 college students, only 428 subjects were determined to have identical constitution through both the questionnaire survey and Korean traditional medical doctors' inquiries. Of 428 subjects, $29.7\%$ were determined to be Tae-Eum-Ins; $35.5\%$ were identified as So-Yang-Ins; $34.8\%$ were classified as So-Eum-Ins. Tae-Eum-Ins showed a statistically significant difference in BMI and higher smoking rate in comparison with groups of So-Yang-Ins and So-Eum-Ins. So-Eum-Ins had a tendency to take vegetables and fruits more often but they had lower preferences for balanced diets. Tae-Eum-Ins showed higher propensity to eat a visible fat protein. In terms of degrees of doneness of meat, So-Yang-Ins showed a higher tendency to prefer well-broiled meat Tae-Eum-Ins also tended to have significantly higher iron, potassium, sodium, vitamin $B_1$, niacin, $\beta$-carotene and vitamin E in their diet So-Eum-Ins had significantly lower intakes of protein, phosphorous, and folate. Considering the fact that most chronic degenerative diseases could be developed by any lifestyle factors, it is necessary to conduct educational programs about lifestyles including dietary habits for maintaining good health; On the basis of the results of this study, it is expected that the scientific, objective and accurate diet information depending upon individual's type of constitution will be provided.

• Journal of Life Science
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• v.34 no.1
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• pp.9-17
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• 2024

Diabetes mellitus (DM) is one of the main global health problems. Chronic exposure to hyperglycemia can lead to cellular dysfunction that may become irreversible over time, a process that is termed glucose toxicity. Our perspective about glucose toxicity as it pertains to the pancreatic β-cell is that the characteristic decreases in insulin secretion are caused by regulated apoptotic gene expression. In this study, we examined whether ferulic acid protects INS-1 pancreatic cells against high glucose-induced apoptosis. High glucose concentration (30 mM) induced glucotoxicity and death of INS-1 pancreatic β cells. However, treatment with 1, 5, 10, or 20 μM ferulic acid increased the cell viability in a concentration-dependent manner. Treatment with ferulic acid dose-dependently decreased the intracellular levels of reactive oxygen species, thiobarbituric acid reactive substances, and nitric oxide in INS-1 pancreatic β cells pretreated with high glucose. These effects influence the apoptotic pathway, increasing the expression of the anti-apoptotic protein Bcl-2 and reducing the levels of pro-apoptotic proteins, including Bax, cytochrome C, and caspase 9. Annexin V/propidium iodide staining indicated that ferulic acid significantly reduced high glucose-induced apoptosis. These results demonstrate that ferulic acid is a potential therapeutic agent to protect INS-1 pancreatic β cells against high glucose-induced apoptosis.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.10 no.1
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• pp.35-44
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• 2002

Inertial Navigation System(INS) has been used in the field of air navigation for a long time but is not popular in general aviation due to high price. Recently low-price GPS is available but vulnerable to radio interference. As an alternative on these problems, GPS/INS integrated navigation system has been considered. GPS/INS is capable of implementing navigation with low-price inertial sensors but its accuracy is dependent upon how much drift of INS may be calibrated by using GPS. In order to apply GPS/INS to air navigation, it must be investigated how long drift of INS in case of no GPS aiding will be bounded within requirements for safe flight. From the above motivation, the flight test for GPS/INS navigation system was conducted in order to make sense its performance in air navigation and its result was shown.

• Journal of Positioning, Navigation, and Timing
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• v.1 no.1
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• pp.45-49
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• 2012

The flight performance evaluation of navigation system is very significant because the reliability of navigation data directly affect the safety of aircraft. Especially, the high-level navigation system such as DGPS/INS, need more precise flight performance evaluation method. The performance analysis is evaluated by comparing between the navigation system in aircraft and reference trajectory which is more precise than navigation system in aircraft. In order to verify DGPS/INS performance of m-level, the GPS receiver, which is capable post-processed Carrier-phase Differential GPS(CDGPS) method of cm-level, have to be used as reference system. The DGPS/INS is estimated the Center of Gravity (CG) point of aircraft to offer precise performance while the reference system is output the position of GPS antenna which is mounted on the outside of aircraft. Therefore, in order to more precise performance evaluation, it needs to compensate the lever arm and coordinates transformation. This paper use quaternion and Direct Cosine Matrix(DCM) methods as coordinate transformation matrix in lever arm compensation of CDGPS reference trajectory. And it compares NED errors of DCM and quaternion transformation in lever arm of reference trajectory via DGPS/INS result.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1995.04a
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• pp.85-85
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• 1995

전년도에 ara-C 유도체 중에서 ara-CDP-DL-PTBA가 각종 암세포주에 대한 뛰어난 항암작용이 보고된바 있으며, 이후 시료의 대량확보, Bulk Formulation 및 전임상등의 세가지 분야에 관해 연구를 수행하였다. Ara-CDP-DL-PTBA를 수용액에 현탁, 초음파분쇄후 NICOMP Analysis에 의하여 micellar solution의 입자도를 알아 본 결과 fresh prepared micelles은 11,1mm size가 88.63%이며 50,5mm가 11.37%로 나타나 평균 19,0mm가 되고, Reconstructed micells은 10.9mm size가 99.87%이며 356.1mm가 0.13%로 나타나 평균 11.0mm가 된다. Ara-C와 Ara-CDP-DL-PTBA의 대사작용을 알아본 결과, ara-C는 투여 1시간째 2,850 $\pm$ 450 pmol, 4시간째 450$\pm$190 pmol, 24시간째 30 pmol 이하로 ara-CTP의 혈중 농도가 급격히 감소하는 반면에 ara-CDP-DL-PTBA는 1시간째 650$\pm$120 pmol, 2시간째 1,800$\pm$500 pmol, 24시간째 300$\pm$90 pmol으로 ara-CTP의 혈중 농도가 서서히 감소하였다.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.40 no.12
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• pp.1086-1092
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• 2012

It has been studied for DGPS/INS(Differential Global Positioning System/Inertial Navigation System) to offer the more precise and reliable navigation data with the aviation industry development. The flight performance evaluation of navigation system is very significant because the reliability of navigation data directly affect the safety of aircraft. Especially, the high-level navigation system, as DGPS/INS, need more precise flight performance evaluation method. The performance analysis is performed by comparing between the DGPS/INS navigation data and reference trajectory which is more precise than DGPS/INS. The GPS receiver, which is capable of post-processed CDGPS(Carrier-phase DGPS) method, can be used as reference system. Generally, the DGPS/INS is estimated the CG(Center of Gravity) point of aircraft while the reference system is output the position of GPS antenna which is mounted on the outside of aircraft. For this reason, estimated error between DGPS/INS and reference system will include the error due to lever arm. In order to more precise performance evaluation, it is needed to compensate the lever arm. This paper presents procedure and result of flight test which includes lever arm compensation in order to verify reliability and performance of DGPS/INS more precisely.

• Journal of Animal Science and Technology
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• v.51 no.2
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• pp.177-182
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• 2009

The glycosylated human MINPP (multiple inositol polyphosphate phosphatase), which was recombinantly over-expressed by using industrial host, Pichia pastoris, showed the phytase activity against phytate ($InsP_6$) and the enzyme activity of the unglycosylated counterpart was decreased to 30%. The optimal phytase activity occurred at pH 7.4. The human MINPP showed high substrate specificity for $InsP_6$ with little activity on other organic phosphate conjugates such as para-nitrophenylphosphate (pNPP), ATP, and ribose-1-phosphate (R-1-P). The phosphatase activity against 2,3-bisphosphoglycerate (2,3-BPG) by human MINPP was increased to 1.2-fold in the presence of stimulator, 1 mM 2-phosphoglycolate (2-PG) but the phytase activity against $InsP_6$ was not affected by addition of 1 mM 2-PG. The phosphatase activity against 2,3-BPG by human MINPP was not increased in the presence of 2 mM $Mg^{2+}$ or 100 mM $Cl^-$.

• 제어로봇시스템학회:학술대회논문집
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• 2002.10a
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• pp.53.1-53
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• 2002

$\textbullet$ Contents 1. Introduction $\textbullet$ Contents 2. Error Models of Navigation $\textbullet$ Contents 3. Observablity Properties of GPS/INS $\textbullet$ Contents 4. Measurement System for INS Error Estimation $\textbullet$ Contents 5. Numerical Simulation Results $\textbullet$ Contents 6. Conclusions

• Journal of Astronomy and Space Sciences
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• v.19 no.4
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• pp.351-366
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• 2002

In this study, we developed low cost INS and (D)GPS integration for continuous attitude and position and utilized it for the determination of exterior orientation parameters of image sensors which are equipped in 4S-Van. During initial alignment process, the heading information was extracted from twin GPS and fine alignment with Kalman filter was performed for the determination of roll and pitch. Simulation and van test were performed for the performance analysis. Based on simulation result, roll and pitch error is around 0.01-0.03 degrees and yaw error around 0.1 degrees. Based on van test, position error in linear road is around 10 cm and curve around 1 m. Using direct georeferencing method, the image sensor's orientation and position information can be acquired directly from (D)GPS/INS integration. 4S-Van achieved 3D spatial data using (D)GPS/INS and image data can be applied to the spatial data integration and application such as contemporary digital map update, road facility management and Video GIS DB.

• Journal of the Korea Institute of Military Science and Technology
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• v.14 no.1
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• pp.49-54
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• 2011

This paper addresses the performance comparisons of the GPS pseudorange and pseudorange rate measurements in the tightly coupled INS/GPS Navigation systems. Even though the two measurements have the same ability in estimating level attitude errors, pseudorange rate has an advantage in improving estimating heading attitude error performance. The performance of pseudorange and pseudorange rate measurements is compared in numerical simulations and van test.