• 아시안잔디학회지
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• 제21권2호
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• pp.127-135
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• 2007

Korea and Japan hosted the FIFA World Cup Soccer Game in 2002. Ten stadiums had been built and more than 30 soccer grounds for practice were renovated in Korea. Sport fields in both countries had problems on cool-season turfgrass growth and quality by summer decline during humid and warm climate especially followed by intensive uses. We measured the effects of air-flow system, which is designed to optimize rootzone soil gas and moisture levels to promote the growth and maintenance turfgrass. This experiment was carried out to verify the effects of the system on soil gas exchange, ground resilience, and turfgrass recovery in turfgrass rootzone. Within 1 or 2hr of operation of the system, rootzone soil gas ($CO_2$, $O_2$) levels returned to natural atmospheric levels completely Soil $CO_2$ levels began to decrease within the first 10 min of operation of the system. The levels were reduced from 1.3 to 0.06% after 30 min, and natural atmospheric levels within 1 hr. When the system was turned off, $CO_2$ levels increased to 0.36% and 0.7% after 5 and 20 hr, respectively. The application of the system did not affect the resilience of turf surface after traffic treatments. Higher traffic treatment resulted in higher surface resilience especially in zoysiagrass plots. Operation of the system had a significant beneficial impact on turf recovery by increased root dry wight and improved turf quality, as compared with the non-operated check plots.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 2002년도 학술대회지
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• pp.351-365
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• 2002

Earlier studies have demonstrated that chromium (Cr) VI compounds have been shown to be more toxic and carcinogenic than other chromium compounds. The aim of the present work was to evaluate the antioxidant effects of red ginseng against chromium VI -induced toxicity and free radical generation. Sixty adult male rats were divided into six equal groups include: control group, group received Cr VI alone (50 mg/kg b.w.), group treated with Korean ginseng (K. ginseng) alone (20 mg/kg b.w), group treated with Cr VI for 15 days then received K. ginseng for other 15 days, group treated with Cr VI and K. ginseng at the same time for 15 days, and group treated with K. ginseng for 15 days then Cr VI for other 15 days. The results revealed that Cr VI caused significant increase in ALT, AST, ALP, G-GT, urea, creatinine, and acid phosphatase. Whereas, it caused significant decrease in TP, albumin, testosterone, GPX, and SOD indicating a stress for liver, kidney and testes. K. ginseng alone caused significant increase in GPX and SOD activities in healthy animals and this result suggests a prophylactic role for this herb in protection against the damaging impact induced by free radical species. Furthermore, the other biochemical parameters measured after K. ginseng administration were comparable to the control values. Treatment with Cr VI followed by K. ginseng, Cr VI and K. ginseng or K. ginseng followed by Cr VI resulted in significant improvement in all tested parameters towards the normal values of the controls. However, this improvement was pronounced in the group pre-treated with K. ginseng for 15 days before Cr VI administration. It could be concluded that K. ginseng exhibited a protective action against the toxic effects of Cr VI and it had the ability to scavenge free radicals resulted from Cr VI intoxication.

• Investigative and Clinical Urology
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• 제59권6호
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• pp.376-382
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• 2018

Purpose: The authors performed this study to investigate the risk factors for predicting stent failure and to evaluate its impact on prognosis. Materials and Methods: Between January 2002 and March 2017, we retrospectively reviewed 117 consecutive patients who underwent retrograde ureteral stenting and exchanging at least once every 3 months for malignant ureteral obstruction. The patients were classified according to their pre-stenting chronic kidney disease (CKD) stage. The factors affecting stent failure were analyzed using a logistic regression model. Overall survival (OS) was estimated, and the prognostic significance of each variable was estimated using Cox proportional-hazards regression modeling. Results: Before stenting, 91 patients were CKD stages 1-3 and 26 patients were CKD stages 4-5. These two groups differed significantly only in pre-stenting estimated glomerular filtration rate (eGFR), bilateral obstruction, and pre-stenting pyuria. Among the 117 patients, stent failure occurred in 30 patients (25.6%), and there were no differences between the groups. Pre-stenting pyuria and post-stenting complications were significant predictors of stent failure. There were 79 deaths in total, including 56 in the CKD stages 1-3 group and 23 in the CKD stages 4-5 group. In the multivariate analysis predicting patient OS, pre-stenting eGFR and post-stenting disease progression were significant factors. Conclusions: Internal ureteral stenting was effective for maintaining renal function in malignant ureteral obstruction. However, it did not restore renal function, which is related to the prognosis of the patients. Therefore, to improve patients' renal function and prognosis, patients who require stenting must be quickly recognized and treated.

• ALGAE
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• 제34권2호
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• pp.141-151
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• 2019

The 1982-83, 1986-87, 1991-92, and 1997-98 El $Ni{\tilde{n}}o$-Southern Oscillations (ENSOs) were compared with regards to their strength and timing in the tropical Pacific Ocean, changes in ocean temperature and wave intensity, and their impacts to giant kelp populations in the Northeast Pacific. The Multivariate ENSO Index, oceanographic data, and kelp abundance data all show that the 1982-83 and 1997-98 ENSOs were stronger and resulted in greater losses of giant kelp than the 1986-87 and 1991-92 ENSOs, but that the 1982-83 and 1997-98 ENSOs differed with regard to the arrival of destructive waves relative to when the ocean waters warmed and cooled. The 1982-83 ENSO was more destructive to the giant kelp populations in central California, USA than the 1997-98 ENSO, but the 1997-98 ENSO was more destructive to the giant kelp in southern California. These events appeared similarly destructive to the populations in Baja California, Mexico. Recovery of the kelp populations also varied among the two strong ENSOs due to the ocean conditions following each ENSO. In southern and Baja California, recovery was slow following the 1982-83 ENSO, while recovery was more rapid following the 1997-98 ENSO. Unfortunately, the monitoring programs used to evaluate the kelp populations stopped shortly after the 1997-98 ENSO, resulting in a lack of data for comparisons with the more recent weak ENSOs that occurred between 2002 and 2010, or with the strong ENSO that occurred in 2014-2016. This supports the need for continued long-term monitoring programs to better understand how climate anomalies impact coastal ecosystems.

• 대한통합의학회지
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• 제8권4호
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• pp.1-11
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• 2020

Purpose : The purpose of this meta-analysis was to examine the effects of microcurrent on inflammatory musculoskeletal diseases. Methods : Domestic databases (RISS, NDSL, KISS, DBpia, and Kmbase) were searched for studies that conducted clinical trials associated with microcurrent and its impact on inflammatory musculoskeletal diseases. A total of 606 studies published between 2002 and 2019 were identified, with 8 studies satisfying the inclusion data. The studies were classified according to patient, intervention, comparison, and outcome (PICO). The search outcomes were items associated with blood component, pain, and function. The 8 studies that were included in the study were evaluated using R meta-analysis (version 4.0). The quality of 7 randomized control trials was evaluated using Cochrane risk of bias (ROB). The quality of 1 non-randomized control trial was evaluated using risk of bias assessment tool for non-randomized studies (RoBANS). Effect sizes were computed as the corrected standard mean difference (SMD). A random-effect model was used to analyze the effect size because of the high heterogeneity among the studies. Egger's regression test was carried out to analyze the publishing bias. Results : The following factors had a large effect size involving microcurrent on inflammatory musculoskeletal diseases: blood component (Hedges's g=-2.46, 95 % CI=-4.20~-0.73), pain (Hedges's g=3.51, 95 % CI=2.44~4.77), and function (Hedges's g=3.06, 95 % CI: 1.53~4.58). Except for function (t=1.572, p=.191), Egger's regression test showed that the publishing bias had statistically significant differences. Conclusion : This study provides evidence for the effectiveness of microcurrent on inflammatory musculoskeletal diseases in terms of blood component, pain, and function. However, due to the small sample sizes used in the included studies, the results of our study should be interpreted cautiously, especially considering the publishing bias.

• Journal of Microbiology and Biotechnology
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• 제31권1호
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• pp.16-24
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• 2021

Hepatitis B virus (HBV) genome P-encoded protein HBV DNA polymerase (Pol) has long been known as a reverse transcriptase during HBV replication. In this study, we investigated the impact of HBV Pol on host cellular processes, mainly apoptosis, and the underlying mechanisms. We showed a marked reduction in apoptotic rates in the HBV Pol-expressed HepG2 cells compared to controls. Moreover, a series of assays, i.e., yeast two-hybrid, GST pull-down, co-immunoprecipitation, and confocal laser scanning microscopy, identified the host factor eEF1A2 to be associated with HBV Pol. Furthermore, knockdown of eEF1A2 gene by siRNA abrogated the HBV Pol-mediated anti-apoptotic effect with apoptosis induced by endoplasmatic reticulum (ER) stress-inducer thapsigargin (TG), thus suggesting that the host factor eEF1A2 is essential for HBV Pol's anti-apoptosis properties. Our findings have revealed a novel role for HBV Pol in its modulation of apoptosis through integrating with eEF1A2.

• Journal of Gastric Cancer
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• 제21권1호
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• pp.16-29
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• 2021

Purpose: Incidence, risk factors, and clinical consequences of pancreatic fistula (POPF) after D1+/D2 radical gastrectomy have not been well investigated in Western patients, particularly those from Eastern Europe. Materials and Methods: A total of 358 D1+/D2 radical gastrectomies were performed by surgeons with high caseloads in a single surgical center from 2002 to 2017. A retrospective analysis of data that were prospectively gathered in an electronic database was performed. POPF was defined and graded according to the International Study Group for Pancreatic Surgery (ISGPS) criteria. Uni- and multivariate analyses were performed to identify potential predictors of POPF. Additionally, the impact of POPF on early complications and long-term outcomes were investigated. Results: POPF was observed in 20 patients (5.6%), according to the updated ISGPS grading system. Cardiovascular comorbidities emerged as the single independent predictor of POPF formation (risk ratio, 3.051; 95% confidence interval, 1.161-8.019; P=0.024). POPF occurrence was associated with statistically significant increased rates of postoperative hemorrhage requiring re-laparotomy (P=0.029), anastomotic leak (P=0.002), 90-day mortality (P=0.036), and prolonged hospital stay (P<0.001). The long-term survival of patients with gastric adenocarcinoma was not affected by POPF (P=0.661). Conclusions: In this large series of Eastern European patients, the clinically relevant rate of POPF after D1+/D2 radical gastrectomy was low. The presence of co-existing cardiovascular disease favored the occurrence of POPF and was associated with an increased risk of postoperative bleeding, anastomotic leak, 90-day mortality, and prolonged hospital stay. POPF was not found to affect the long-term survival of patients with gastric adenocarcinoma.

• East Asian mathematical journal
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• 제38권5호
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• pp.617-641
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• 2022

In this study, we first present a brief overview of the Korean general insurance market. We then explore the characteristics of the loss ratios of the Korean general insurance industry and apply Markov regime-switching methodology to model the loss ratios of these insurance companies by line of business based on changes in economic regimes. This study applies a number of confirmatory tests such as Zivot-Andrews test (2002), the Chow (1960) test and the Bai and Perron (1998) to confirm the presence of structural breaks in the time series of the loss ratios by line of business. Then, we employ Markov regime-switching methodology to model these loss ratios. We find empirical evidence that the loss ratios reported by insurance companies in Korea is characterized by two distinct regimes; a regime with high volatility and a regime with low volatility, except for vehicle insurance. Our analyses suggest that macro-economic conditions have significant explanatory effect on loss ratios but the direction of effect differs based on the line of business and the regime. Unlike previous studies that have applied linear regressions or divided the samples into different periods and then apply linear regressions to model loss ratios, we argue for the application of Markov regime-switching methodology, which are able to automatically distinguish the different regimes that may be associated with the movements of loss ratios based on differing economic conditions and regulatory upheavals. This study provides a more in depth understanding of loss ratios in the general insurance industry and will be of value to insurance practitioners in modelling the loss ratios associated with their businesses to aid in their decision making. The results may also provide a basis for further studies in other markets apart from Korea as well as for shaping policy decisions related to loss ratios.

• 한국콘텐츠학회논문지
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• 제22권2호
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• pp.593-604
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• 2022

본 연구는 기업의 노동투자비효율성에 대한 감사인의 반응에 대해 분석하였다. 구체적으로 노동투자비효율성이 감사보수와 감사시간에 미치는 영향에 대해 검증하였다. 비효율적인 노동투자가 이루어지는 기업일수록 감사인들은 사업위험을 높게 평가하여 감사위험이 증가한 것으로 인식하게 된다. 이로 인해 높아진 감사위험을 낮추기 위해 감사범위를 확대하고 충분한 감사증거를 수집하려는 유인이 있다. 따라서 감사인들은 더 높은 감사보수를 요구하고, 추가된 감사노력으로 인해 감사시간이 증가할 것으로 예상된다. 2002년부터 2018년까지 유가증권시장 및 코스닥시장에 상장된 기업을 대상으로 분석한 결과, 노동투자에 대한 비효율성이 증가할수록 감사보수와 감사시간은 증가하는 것으로 나타났다. 이러한 결과는 감사인들이 노동투자의 비효율성이 높은 기업에 대해 사업위험이 높은 것으로 평가하여 이에 대한 보상으로 높은 감사보수를 요구한다는 것으로 해석된다. 또한 감사인들이 감사위험을 낮추기 위해 추가적인 감사시간을 투입한다는 것을 시사하고 있다. 본 연구는 기업의 경쟁력을 결정하는 중요한 요소인 인력에 대한 투자가 비효율적으로 이루어지는 경우 감사보수와 감사시간이 증가한다는 실증적인 근거를 제시하였다는 점에서 공헌점을 찾을 수 있다.

• 한국지형학회지
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• 제26권1호
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• pp.41-57
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• 2019

The grain size characteristics of river sediments and the characteristics of bedrock were investigated for the 24km section of the Dong River upstream of the Han River. The bedrock of the study area is various limestone belonging to the Paleozoic Choseon limestone group, and Mesozoic sandstone and conglomerate occur in some areas. Most of the river channel is made of limestone, and most of the river bottom is covered with fluvial sediments. More than 70% of these sediments are sandstone and conglomerate, rather than limestone which forms the basis of the valley. Sediment particles seem to have been supplied upstream of the study area rather supplied from the slope near of the channel. It is difficult to find the statistically significant difference in the shape of the sediment particles of limestones and non-limestones. However, limestones has platy forms rather than block forms, it can be assumed that the limestone was supplied from the surrounding valley wall and transported over a short distance. The particle sizes of DG1~DG2(the upstream section) are decreasing in the downstream direction. However, at DG3, which is a tributary, Jijangcheon, confluence particle size increases and at DG4 particle size increases more. In the case of DG4, it may be influenced by the influx of tributaries, but it also can be supposed as the impact of the large flood in 2002. In the downstream parts(DG5~DG7), the particle size decreases exponentially with distance. The rebound strength of stream sediments and bedrock was measured by using Schmidt hammer. Limestone showed lower rebound strength than non-limestone. According to the results of the sediment and bedrock, it can be seen that the sandstone and conglomerate with high rebound values pass through valley with the relatively low strength limestone. The sediments of limestone were decreased in grain size more rapidly than those of limestone sediments.