• Journal of Nutrition and Health
• /
• v.6 no.2
• /
• pp.17-24
• /
• 1973

The function of the liver is so complicated and important that various Hepatic diseases are occured due to functional retardation of liver. Above all, the incidence of Hepatitis and liver cirrhosis among Koreans has shown an increasing tendency recently. 113 cases of Hepatitis and 125 cases of liver cirrhosis which had been admitted, more than 10 days, to KOREA Hospital between November, 1968 and July,1972, were studied through clinic charts. (A) Hepatitis 1) of the 113 cases; 54 cases (47.7%) were Infectious hepatitis; 40 cases (35.4%) were chronic hepatitis 2) of the 113 cases ; 80 cases (70.8%) were male and 33 cases (29.2%) were female; the sex ratio was 2.4 : 1 The ages of the onset of the disease was as follows; 34 cases (30.1%) were among $30{\sim}40$. 3) Patients had abdominal pain (77.9%) anorexia (66.4 %) and general weakness(82.3%) as symptom and jaundice (94.7%) hepatomegaly (76.1%) as sign 4) 57 cases of all had complication 26 cases (45.6%) were parasite, 12 cases (21.1%) were diabeties mellitus. 5) 99 casea (87.6%) of all were improved and recovered. (B) Liver Cirrhosis 1) Etiologic factors are hepatitis (56cases) and alcoholics (28 cases). 2) of the 125 cases, 84 cases (67.2%) were male and 41 cases (32.8%) were female; the sex ratio was 2 : 1 The age of the onset of the disease was as follows; 47 cases (37.6%) were among 41-50. 3) Patients had symptoms: indigestion (64.8%), Abdominal pain (60%), general wenkness (35.2%) and signs; Hepatomegaly (61.6%) Ascites (59.2%), Jaundice(56.8%). 4) 107 cases of all had complications; Hepatic coma was 20 cases (18.7 %), Ascites was 16 cases (15.0%). 5) 69 cases (55.2%) were improved. (c) Treatment of Hepatitis and cirrhosis. 1) Absolutely (bed) rest. 2) A well-balanced diet adequate in calorie value, showed be given (High Carbohydrate, High Protein, High vitamin diet) if the patient's appetite is good and easily digested. 3) Drugs; (1) Vitamins (2) Digestants (3) Tranquize

• Journal of Korean Society of Steel Construction
• /
• v.12 no.1 s.44
• /
• pp.45-54
• /
• 2000

Design-oriented approximate structural reanalysis models are compared and assessed, particularly with focus on the case of large changes of design variables. The effectiveness and reliability are demonstrated by means of numerical examples. The results of the study suggest the following conclusions relative to the potential of the procedures. (A) local approximation is only appropriate for the case of small changes in design : (B) global approximation is exact for the case of large changes in a small number of design variables, but inefficient : (C) local-global approximation is most effective and reliable for the case of large changes with a large number of design variables. These methods can improve the total efficiency when they are appropriately used to the design information for the redesign process of large scale structures.

• Journal of Periodontal and Implant Science
• /
• v.44 no.1
• /
• pp.8-12
• /
• 2014

Purpose: The aim of this retrospective chart review was to evaluate the four-year survival rate of a titanium implant system. Methods: A total of 352 sand-blasted, thermally acid-etched titanium implants were inserted into 181 partially or completely edentulous patients. Their cumulative survival rate was evaluated retrospectively. Associated factors, such as the implant distribution and treatment type were included in the evaluation. Results: The implants were equally distributed between the maxilla (52.3%) and the mandible (47.7%). 48 implants (13.6%) were placed in the anterior region and 304 implants (86.4%) in the posterior region. The majority of the implants were inserted into bone of type II and III quality (89.8%) and volume (quantity B and C, 87.2%). Most of the implants (70.7%) were restored as single crowns; 28.7% supported a bridge construction and 0.6% a full denture. Only one implant failed, resulting in a four-year cumulative survival rate of 99.7%. Conclusions: The implant system showed an excellent four-year survival rate. It proved to be a safe and predictable means for restoration of the dentition in partially or completely edentulous patients.

• Journal of the Korean Wood Science and Technology
• /
• v.42 no.5
• /
• pp.571-578
• /
• 2014

As a way of developing wooden joint development, a glass fiber reinforced wood plate was manufactured to replace a steel plate. Also, the fracture toughness was evaluated. Through application to a cantilever-type specimen made of a column and a beam, the moment resistance performance was evaluated. For the fracture toughness specimen of the wood plate, 12 types were manufactured by varying the combination of a main member (veneer and plywood) and reinforcement (glass fiber sheet and glass fiber cloth). The results of the fracture toughness test indicated that the 5% yield load of the specimen using plywood was 18% higher than that of the specimen using veneer, and that the specimen reinforced by inserting glass fiber sheets between testing materials (Type-3-PS) had the highest average 5% yield load 4841 N. Thus, a moment resistance strength test was performed by applying Type-3-PS to a column-beam joint. The results of the test indicated that compared to the specimen using a steel plate and a drift pin (Type-A), the maximum moment ratio of the specimen using a glass fiber reinforced wood plate (Type-3-PS) and a drift pin (Type-B) was 0.79; and that a rupture occurred in the wood plate due to high stiffness of the drift pin. The maximum moment ratio of the specimen using a glass fiber reinforced wood plate (Type-3-PS) and a glass fiber reinforced wooden laminated pin (Type-C) was 0.67, which showed low performance. However, unlike Type-A, a ductile fracture occurred on Type-C, and the load gradually decreased even after the maximum moment.

• The korean journal of orthodontics
• /
• v.45 no.1
• /
• pp.3-12
• /
• 2015

Objective: We compared the skeletal and dental changes that resulted from the use of two methods of intermaxillary fixation (IMF)-miniscrews and surgical archwire-in 74 adult patients who had Class III malocclusion and were treated with the same orthognathic surgical procedure at a hospital in Korea. Methods: All the patients underwent Le Fort I osteotomy and bilateral sagittal split ramus osteotomy with rigid fixation. They were divided into two groups according to the type of IMF used-group 1 underwent surgical archwire fixation and group 2 underwent orthodontic miniscrew fixation. In a series of cephalograms for each patient, we compared vertical and horizontal tooth-position measurements: (a) immediately after surgery ($T_0$), (b) 3 months after surgery ($T_1$), and (c) 6 months after surgery ($T_2$). Cephalometric changes within each group were examined using one-way analysis of variance (ANOVA) while the independent samples t -test procedure was used to compare the two groups. Results: After surgery, the maxillary incisors tended to be proclined in both groups although there were no significant differences. Incisor overbite increased significantly in both groups from $T_0$ to $T_1$, and the miniscrew group (group 2) showed slightly greater overbite than the archwire group (group 1). Conclusions: This study suggest that the use of orthodontic miniscrews and orthodontic surgical archwire for IMF in adult patients results in similar skeletal and dental changes.

• BMB Reports
• /
• v.39 no.6
• /
• pp.686-695
• /
• 2006

Interleukin-2 enhancer binding factor 2 (ILF2) was reported to regulate transcription of interleukin-2 (IL-2), a central cytokine in the regulation of T-cell responses. This property of ILF2 was well characterized in human and mammals, but little is known in bony fish. In this paper, an ILF2 homologue was cloned and well characterized from Tetraodon nigrovirid is for the further investigation of the function of ILF2 in bony fish. The full-length Tetraodon ILF2 cDNA was 1380 bp in size and contained an open reading frame (ORF) of 1164 bp that translates into a 387 amino-acid peptide with a molecular weight of 42.9 kDa, a 5' untranslated region (UTR) of 57 bp, and a 3' UTR of 159 bp containing a poly A tail. The deduced peptide of Tetraodon ILF2 shared an overall identity of 58%~93% with other known ILF2 sequences, and contained two N-glycosylation sites, two N-myristoylation sites, one RGD cell attachment sequence, six protein kinase C phosphorylation sites, one amino-terminal RGG-rich single-stranded RNA-binding domain, and a DZF zinc-finger nucleic acid binding domain, most of which were highly conserved through species compared. Constitutive expression of Tetraodon ILF2 was observed in all tissues examined, including gill, gut, head kidney, spleen, liver, brain and heart. The highest expression was detected in heart, followed by liver, head kidney and brain. Stimulation with LPS did not significantly alter the expression of Tetraodon ILF2. Gene organization analysis showed that the Tetraodon ILF2 gene have fifteen exons, one more than other known ILF2 genes in human and mouse. Genes up- and down-stream from the Tetraodon ILF2 were Rpa12, Peroxin-11b, Smad4, Snapap and Txnip homologue, which were different from that in human and mouse.

• BMB Reports
• /
• v.44 no.11
• /
• pp.758-763
• /
• 2011

Immunostimulatory CpG-DNA targeting TLR9 is one of the most extensively evaluated vaccine adjuvants. Previously, we found that a particular form of natural phosphodiester bond CpG-DNA (PO-ODN) encapsulated in a phosphatidyl-${\beta}$-oleoyl-${\gamma}$-palmitoyl ethanolamine (DOPE) : cholesterol hemisuccinate (CHEMS) (1 : 1 ratio) complex (Lipoplex(O)) is a potent adjuvant. Complexes containing peptide and Lipoplex(O) are extremely useful for B cell epitope screening and antibody production without carriers. Here, we showed that IL-12 production was increased in bone marrow derived dendritic cells in a CpG sequence-dependent manner when PO-ODN was encapsulated in Lipoplex(O), DOTAP or lipofectamine. However, the effects of Lipoplex(O) surpassed those of PO-ODN encapsulated in DOTAP or lipofectamine and also other various forms of liposome-encapsulated CpG-DNA in terms of potency for protein antigen-specific IgG production and Th1- associated IgG2a production. Therefore, Lipoplex(O) may have a unique potent immunoadjuvant activity which can be useful for various applications involving protein antigens as well as peptides.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.30 no.12B
• /
• pp.831-837
• /
• 2005

Personal general purpose computer(PC) has been evolved from desktop to portable mobile device such as tablet PC and PDA. Technology innovation on semiconductor have made it possible to package a reasonably Powerful Processor and memory subsystem with advanced input/output devices. At last these subsystems are miniaturized into wearable system. Wearable computer has recently gained attention as the post PC in the ubiquitous environment. Wearable computing becomes more and more feasible and receives growing attention throughout industry and the consumer marketplaces. This paper proposed and developed WPS that has multimedia features and network features as a wearable embedded platform. We explain the form, overall architecture, functions and user applications of this WPS. This paper also discusses the form of next generation computer platform with intuitive user interfaces and well designed applications in the future.

• The Journal of Korean Medicine
• /
• v.25 no.3
• /
• pp.137-148
• /
• 2004

Objectives : To study change of external dermal formation, change of leukocytes in vasculature, change of lipid formation in stratum corneum and distribution of ceramide through administering Sihocheonggan-san (SC) extract on to the control (CON). This study was done through forcing injury to mice's back skin which have lipid protection formation in stratum corneum. Materials and Methods : The CON to which damage was caused intentionally using the external application on the mice's back skin used the SC. The change of leukocytes in vasculature were identified through optima 5.2 and Student's t-test and the results were made into a dermal formation graph. Results : After dispensing SC extract into the CON, dermal injury was decreased. Especially, recover of lipid protection formation, which includes lipid and ceramide in stratum corneum suppressing acute inflammation that some factors are PKC, TNF-α, IL-12B which controlled the secretion of relating inflammatory cytokine, also went onto decrease of angiogenesis, and a decrease of degranulated mast cells was noted. In addition, the decrease of epithelial injury also caused the growth of cells to decrease in stratum basale and cytoclasis. In the vasculature, the leukocytes were also decreased and it could relate to decrease in CON. Conclusions : SC has effect on CON suppressing the dermal injury through recovering of lipid protection formation in stratum corneum.

• Korean Journal of Community Nutrition
• /
• v.10 no.4
• /
• pp.462-470
• /
• 2005

The purpose of this study was to determine the characteristics of infants' temperaments, maternal feeding behaviors and feeding practices in picky eaters. Participants were 83 infants (aged 12 - 24 months) from 'A' hospital (Seoul) and 'B' public health center (Kyunggido). Mothers completed questionnaires that assessed their own feeding behavior, feeding practices, infants' temperament and infants' feeding behavior. Picky eaters' demographics were not significantly different from non-picky eaters after adjusting sex and age. The average of thiamin, niacin and vitamin E intakes of picky eaters were below $75\%$ Korean RDA, whereas vitamin A intakes exceed $120\%$ RDA in both groups. Activity level of infants' temperament and disinhibition of maternal feeding behavior in picky eaters were significantly higher than those in non-picky eater. All constructs of infants feeding behavior were significantly associated with certain constructs of infants' temperament, maternal feeding practice and maternal feeding behavior. The pickiness of infants feeding behavior was positively correlated with activity level of infants' temperament, pickiness and disinhibition of maternal feeding behavior and negatively correlated with adaptability of infants' temperament. Findings suggest that maternal feeding behavior and feeding practices as well as infants' temperament should be addressed in nutrition education for picky eaters.