• Title/Summary/Keyword: IL-6 and IL-10

Search Result 8,985, Processing Time 0.046 seconds

Changes of Storability and Quality Characteristics of 'Autumn Sense' Hardy Kiwifruit According to Ethylene Treatment and Storage Condition (에틸렌 처리와 저장조건에 따른 '오텀센스' 다래의 저장성 및 품질특성 변화)

  • Oh, Sung-Il;Kim, Chul Woo;Kim, Mahn-Jo
    • Journal of Korean Society of Forest Science
    • /
    • v.103 no.3
    • /
    • pp.368-374
    • /
    • 2014
  • This study was investigated the changes of storability and quality characteristics of 'Autumn Sense' hardy kiwifruit according to ethylene treatment and storage condition. In the results of investigation of changes in hardy kiwifruit quality during storage period, hardness of ethylene treated hardy kiwifruit during 48 and 96 hours was rapidly decreased, but soluble solid content was rapidly increased with the passing of storage period in all treatment groups. The total acid was estimated from 0.7 to 1.4% with storage period in all treatment groups. In the results of investigation of the weight loss rate, ethylene treated hardy kiwifruit during 48 hours was the highest 30.9% in storage at $20^{\circ}C$ and lowest 5.9% in storage at $2^{\circ}C$ with a relative air humidity of about 90% during storage at 24 days. Ethylene treated hardy kiwifruit during 96 hours was decrease 29.4% in storage at $20^{\circ}C$, 20.7% in storage at $4^{\circ}C$, 12.1% in storage at $2^{\circ}C$, and 6.0% in storage at $2^{\circ}C$ with a relative air humidity of about 90% during storage at 22 days. The taste of hardy kiwifruit during storage was reduced to increase in all treatment groups. Particularly, storage at $20^{\circ}C$ was rapidly reduced to increase in the early storage and storage at $2^{\circ}C$ with a relative air humidity of about 90% was decrease after storage at 18 days. The rotten rate during storage was increased in all treatment groups, storage at $20^{\circ}C$ was after storage at 2 days and storage at $2^{\circ}C$ with a relative air humidity of about 90% was rapidly increased after storage at 16 days. Thus, it can be recommended that storage at $2^{\circ}C$ with a relative air humidity of about 90% is good to maintain quality. Also, we will decide optimal storage condition and after-ripening time of 'Autumn Sense' hardy kiwifruit.

Characterization and β-secretase Inhibitory Activity of Water-soluble Polysaccharides Isolated from Phellinus linteus Fruiting Body (상황버섯 자실체로부터 분리된 수용성 다당류의 특성 분석 및 이의 베타 시크리타아제 활성 저해효과)

  • Jo, Hang Soo;Choi, Doo Jin;Chung, Mi Ja;Park, Jae Kweon;Park, Yong Il
    • The Korean Journal of Mycology
    • /
    • v.40 no.4
    • /
    • pp.229-234
    • /
    • 2012
  • A key molecule in the pathogenesis of Alzheimer's disease (AD) is the ${\beta}$-amyloid peptide ($A{\beta}$) generated by ${\beta}$-secretase activity, an aspartic protease. This study was designed to evaluate inhibitory effect of the high-molecular weight water-soluble polysaccharides (Et-P) isolated and purified from Phellinus linteus fruiting body on ${\beta}$-secretase activity. The Et-P was purified from the hot water extract of Phellinus linteus fruiting body mainly by 75% ethanol precipitation and DEAE-Cellulose column chromatography. From the DEAE-Cellulose chromato-gram and molecular weight analysis, the Et-P was shown to be a mixture of three polysaccharides with molecular mass of 1,629, 1,294, and 21 kDa, respectively. The monosaccharide composition of Et-P was determined to be glu-cose, galactose, and mannose as major sugars, glucose being the most prominent one (48% in mole percentage). The elemental analysis and FT-IR analysis suggested that Et-P is typical polysaccharides having at least partially ${\beta}$-linkages and possible existing as complex with phenolic compounds. The laminarinase digestion and HPAEC-PAD analysis suggested that Et-P is a variant of beta-(1,3)-glucans. The Et-P showed DPPH radical scavenging activity and, especially, a significant inhibitory activity on ${\beta}$-secreatase activity (48% inhibitin at 100 ${\mu}g/mL$), suggesting that they may inhibit the formation of $A{\beta}$ which is the major causative of Alzheimer's disease. The results of this study suggest that the water soluble polysaccharides of Phellinus linteus fruiting body can be a potent material for the development of preventive or therapeutic agents for AD.

The evaluation of color and color difference according to the layering placement of Incisal shade composites on the body composites of the indirect resin restoration (간접 수복용 복합레진의 Incisal 색상 적층 두께에 따른 표면 색상 및 색차의 평가)

  • Park, Su-Jung;Lee, Han-Young;Nah, Myong-Yun;Chang, Hoon-Sang;Hwang, Yun-Chan;Oh, Won-Mann;Hwang, In-Nam
    • Restorative Dentistry and Endodontics
    • /
    • v.36 no.1
    • /
    • pp.37-49
    • /
    • 2011
  • Objectives: The aim of this study was to evaluate the surface color of indirect resin restoration according to the layering placement of different shade of incisal composite. Materials and Methods: In this study, CIE $L^*a^*b^*$ value of 16 Body composite of Tescera ATL (Bisco, Schaumburg IL,USA) was measured by spectrophotometer (NF999, Nippon Denshuku, Japan), and compared to CIE $L^*a^*b^*$ value of Vitapan shade guide. Nine shade Incisal composite of Tescera ATL were buildup to 1 mm thickness on Body composites inlay block, and CIE $L^*a^*b^*$ value was measured. Incisal composite was ground to 0.5 mm thickness and CIE $L^*a^*b^*$ value was re-measured. Color difference between Body composite and Incisal composites layered on Body composite was calculated as a function of thickness. Results: Color difference between corresponding shade of Tescera Body composite and Vitapan shade guide was from 6.88 to 12.80. $L^*$ and $b^*$ value was decreased as layering thickness of Incisal composite on Body composite was increased. But, $a^*$ value did not show specific change tendency. Conclusions: Surface color difference between Body composites and Incisal composites layered on Body composite was increased as the layering thickness of Incisal composite increased (p < 0.05).

Analysis of Spatial Correlation between Surface Temperature and Absorbed Solar Radiation Using Drone - Focusing on Cool Roof Performance - (드론을 활용한 지표온도와 흡수일사 간 공간적 상관관계 분석 - 쿨루프 효과 분석을 중심으로 -)

  • Cho, Young-Il;Yoon, Donghyeon;Lee, Moung-Jin
    • Korean Journal of Remote Sensing
    • /
    • v.38 no.6_2
    • /
    • pp.1607-1622
    • /
    • 2022
  • The purpose of this study is to determine the actual performance of cool roof in preventing absorbed solar radiation. The spatial correlation between surface temperature and absorbed solar radiation is the method by which the performance of a cool roof can be understood and evaluated. The research area of this study is the vicinity of Jangyu Mugye-dong, Gimhae-si, Gyeongsangnam-do, where an actual cool roof is applied. FLIR Vue Pro R thermal infrared sensor, Micasense Red-Edge multi-spectral sensor and DJI H20T visible spectral sensor was used for aerial photography, with attached to the drone DJI Matrice 300 RTK. To perform the spatial correlation analysis, thermal infrared orthomosaics, absorbed solar radiation distribution maps were constructed, and land cover features of roof were extracted based on the drone aerial photographs. The temporal scope of this research ranged over 9 points of time at intervals of about 1 hour and 30 minutes from 7:15 to 19:15 on July 27, 2021. The correlation coefficient values of 0.550 for the normal roof and 0.387 for the cool roof were obtained on a daily average basis. However, at 11:30 and 13:00, when the Solar altitude was high on the date of analysis, the difference in correlation coefficient values between the normal roof and the cool roof was 0.022, 0.024, showing similar correlations. In other time series, the values of the correlation coefficient of the normal roof are about 0.1 higher than that of the cool roof. This study assessed and evaluated the potential of an actual cool roof to prevent solar radiation heating a rooftop through correlation comparison with a normal roof, which serves as a control group, by using high-resolution drone images. The results of this research can be used as reference data when local governments or communities seek to adopt strategies to eliminate the phenomenon of urban heat islands.

A Seismic Study on Muddy Sediment Deposits in the Northern Shelf of the East China Sea (동중국해 북부대륙붕에 발달한 니질 퇴적체의 탄성파 연구)

  • Choi Dong-Lim;Lee Tae-Hee;Yoo Hae-Soo;Lim Dhong-Il;Huh Sik;Kim Kwang-Hee
    • Economic and Environmental Geology
    • /
    • v.38 no.6 s.175
    • /
    • pp.633-642
    • /
    • 2005
  • We present the sedimentary sequence and distribution pattern of the late Holocene muddy deposits in the northern East China Sea shelf using the high-resolution 'Chirp' profiles. The seismic sedimentary sequence overlying acoustic basement (basal reflector-B) can be divided into two depositional units (Unit 1 and 2) bounded by erosional bounding surface (mid reflector-M). The lower Unit 1 above basal reflector-H is characterized by the acoustically parallel to subparallel reflections and channel-fill facies. The upper Unit 2, up to 7 m in thickness, shows seismically semi-transparent seismic facies and lenticular body form. On the base of sequence stratigraphic concept, these two sediment units have developed during transgression and highstand period, respectively, since the last sea-level lowstand. The transgressive systems tract (Unit 1) lie directly on the sequence boundary (reflector B) that have farmed during the last glacial maximum. The transgressive systems tract in this study consists mostly of complex of delta, fluvial, and tidal deposits within the incised valley estuary system. The maximum flooding surface (reflector M) corresponding to the top surface of transgressive systems tract is obviously characterized by erosional depression. The highstand systems tract (Unit 2) above maximum flooding surface is made up of the mud patch filled with the erosional depression. The high-stand mud deposits showing a circle shape just like a typhoon symbol locates about 140 km off the south of Cheju Island with water depth of $60\~90m$. Coverage area and total sediment volume of the mud deposits are about $3,200km^2$ and $10.7\times10^9\;m^3$, respectively. The origin of the mud patch is interpreted as a result of accumulating suspended sediments derived from the paleo-Yellow and/or Yangtze Rivers. The circular distribution pattern of the mud patch appears to be largely controlled by the presence of cyclonic eddy in the northern East China Sea.

Effects of Olanzapine on the Schedule-Induced Polydipsic Rats (Olanzapine이 백서의 Schedule-Induced Polydipsia에 미치는 영향)

  • Lee, Gi-Chul;Lee, Kyung-Kyu;Chang, Hwan-Il;Lee, Jung-Ho;Kim, Hyun-Woo;Ha, Jun-Myung;Jeong, Jae-Hyun;Jeong, Hong-Kyung
    • Korean Journal of Biological Psychiatry
    • /
    • v.6 no.2
    • /
    • pp.240-245
    • /
    • 1999
  • Object : This study was designed to evaluate the effects of olanzapine on the schedule-induced polydipsia(SIP) which is one of animal model of obsessive-compulsive disorder in rats. We administered olanzapine as a serotonin and dopamine blocking agent, fluoxetine as a selective serotonin reuptake inhibitor, and haloperidol for the dopamine antagonist to rats which showed schedule-induced polydipsic behavior. Methods : Spraque-Dawley rats weighing 200-250gm were individually housed and maintained and allowed free access to water. The rats were placed on a restricted diet. To induce polydipsia, rats were placed in the cage where a pellet dispenser automatically dispensed 90mg pellets on a fixed-time 60 seconds(FT-60s) feeding schedule over 150 minute test session per day. Water was available at all times in the cage. After 4 weeks of daily exposure to the FT 60s feeding schedule, experimental rats met a predetermined criterion for polydipsic behavior(greater than 3 times of water per session on average). 5 groups of rats were administered olanzapine(3mg/kg, i.p), olanzapine(10mg/kg, i.p), fluoxetine(5mg/kg, i.p.), haloperidol(0.1mg/kg, i.p.), and vehicle(1cc/kg, i.p.) for 3 weeks. The rats were tested once a week to access schedule induced polydipsic behavior. Water bottles were weighed before and after the 150-minute test session. The chronic effects of administration of experimental drugs on schedule induced polydipsic behavior were analyzed with ANOVA and Scheffe test as a posthoc comparison. In order to measure water consumption in non-polydipsic food-deprived rats, a separate group of rats(N=8) were individually housed and given a single bolus(14.5gm) of food per day which maintained them at their average body weight. Results and Conclusion : The results were as follows ; 1) After 4 weeks of scheduled feeding procedure, the experimental group showed significant differences than the bolus control in the amount of water consumption as compared with their average water intakes for 4 weeks. At the same periods, there were no differences between the experimental group and the bolus control in the body weight. 2) The fluoxetine group showed significant decrease in the amount of water intake over the 3 weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 3mg group showed significant decrease in the amount of water intake at 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. The olanzapine 10mg group showed significant decrease in the amount of water intake at 2nd and 3rd weeks of drug treatment as compared with their average amount of polydipsic water intakes. However, the haloperidol group and the vehicle control group showed no changes of amounts of water intake for 3 weeks of treatment as compared with their average amount of polydipsic water intakes. 3) The fluoxetine group showed significantly lower amounts of water intake than the haloperidol group at 2nd weeks of drug treatment. And also the fluoxetine group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. The olanzapine 3mg group and the olanzapine 10mg group showed significantly lower amounts of water intake than the haloperidol group and the vehicle control at 3rd weeks of drug treatment. Above findings suggest that the fixed time feeding procedure for schedule-induced polydipsia as an animal model of obsessive compulsive disorder was effective to the evaluation of pharmacological challenge study. The authors assume that the serotonin hypothesis and the serotonin-dopamine interaction hypothesis are preferred to the dopamine hypothesis in the biological etiology of obsessive-compulsive disorder.

  • PDF

Dietary Brown Seaweed Modulates Nutrient Metabolism, Anti-oxidant System and Immune Response in Broiler Chicks Injected LPS i.p. (사료 중 미역은 복강내 LPS 주입 육계 병아리에서 영양소 대사, 항산화계 및 면역 반응을 조정한다)

  • Park, In-Kyung;Im, Jin-Taek;Choi, Do-Yul;Koh, Tae-Song
    • Journal of Animal Science and Technology
    • /
    • v.50 no.2
    • /
    • pp.185-198
    • /
    • 2008
  • Influences of dietary brown seaweed(BSW) on the nutrient metabolism, anti-oxidant enzyme activity and cell-mediated immune response were studied in broiler chicks activated acute phase response. 72 Hatched male broiler chicks(Ross) were divided into 12 pens, 6 heads per pen, and fed the BSW 0.0% (Basal) or 2.0% diet, respectively, and injected with the Salmonella typhimurium lipopoly saccharide(LPS) for activation of the acute phase response three times at 8, 10 and 12 d of age. During 4 wks of experimental feeding, growth performance of broiler chicks was not affected by dietary BSW and the acute phase response. Compared with control birds, the acute phase response did not affect the daily weight gain in birds fed BSW 2.0% diet, decreased nitrogen balance(NB) or metabolizable energy(ME) utilization per metabolic body size(kg0.75), and enhanced activities of peroxidase or extracellular SOD(EcSOD), tumor necrosis factor-alpha and ovotransferrin in plasma and MnSOD and CuZnSOD in erythrocyte cytosol. Compared to BSW 0.0% diet, 2.0% diet enhanced protein retention(NB) per kg0.75 regardless the acute phase response, did not affect uric acid nitrogen excretion(UAN) per kg0.75 in birds during the acute phase response, decreased(p<0.05) the UAN excretion per kg0.75 in control birds. And BSW 2.0% diet also decreased(p<0.05) plasma peroxide level and erythrocyte peroxidase or MnSOD activity but increased plasma peroxidase and EcSOD activity and interleukin-1 activity secreted from LPS-stimulated PBMC in 4 week broiler chicks.

Studies on the UV Spectrum of AcBr Lingin from Hardwood Grown in Mt. Jiri (지리산산(智異山産) 활엽수재(闊葉樹材) AcBr(acetyl bromide) Lignin의 UV Spectrum에 대(對)한 고찰(考察))

  • Lee, Dong-Il;Moon, Chang-Kuck
    • Journal of the Korean Wood Science and Technology
    • /
    • v.14 no.4
    • /
    • pp.14-20
    • /
    • 1986
  • These experiments were carried out to determine the ultraviolet absorption spectra of AcBr lignins(acetyl bromide lignin) from 10 hardwood species grown in Mt. Jiri. 1. There were 3 peak positions, at 249nm(max. peak), at 262-266nm(shallow min. peak) and at 270-280nm(lower max. peak). The Bj$\ddot{o}$rkman lignin and lignin sulfonatic acid spectra had shoulders, but the AcBr lignin didn't. 2. Average absorbances of the AcBr lignin at peak positions were 0.457${\pm}$0.0077 at 249nm, 0.297${\pm}$0.0029 at 262-266nm and 0.309${\pm}$0.0067 at 270-280nm. 3. Average absorptivities of the AcBr lignin at peak positions were 25.005${\pm}$0.3825 at 249nm, 16.264${\pm}$0.2347 at 262-266nm and 16.863${\pm}$0.3444 at 270-280nm. 4. AcBr lignin absorptivities in each species were as follows: 16.939${\pm}$0.3735 in Acer pseudo-sieboldianum var. koreanum, 17.411${\pm}$0.2937 in Carpinus laxiflora, 16.579${\pm}$0.4348 in Comus controversa, 16.385${\pm}$0.4140 in Fraxinus rhynchophylla, 16.287${\pm}$0.4156 in Meliosma myriantha, 16.492${\pm}$0.1432 in Platycarya strobilacea, 16.343${\pm}$0.3177 in Prunus sargentii, 17.549${\pm}$0.3253 in Sophora japanica, 18.400${\pm}$0.2925 in Stewartia koreana, 16.245${\pm}$0.4339 in Styrax obassia. 5. As the spectra of AcBr lignin from hardwood showed the unpromounced peak from 270nm to 280nm, it was supposed that thes hardwood lignins were the guaiacyl-syringyl copolymers.

  • PDF

The Effect of the Dental Patients' Perception about Dental Hygienist on the Social Demand of Dental Hygienist (치과 내원환자들의 치과위생사에 대한 인식도가 치과위생사의 사회적 요구도에 미치는 영향)

  • Choi, Jung-Mi;Lee, Eun-Ju
    • Journal of dental hygiene science
    • /
    • v.12 no.4
    • /
    • pp.392-403
    • /
    • 2012
  • This study aims at providing the basic data to help establish the right identity of dental hygienist and develop the work of dental hygienists, and thereby investigating the effect of patients' perception of dental hygienist on their social demand of dental hygienist, by conducting a survey of 300 patients visiting dentists around Busan-Gyeongnam region from April 7, 2012 to April 25, 2012. The collected data is statistically analyzed by SPSS (Statistical Packages for Social Science 14.0. SPSS Inc., Chicago, IL, USA). First, I analyzed the frequency by suggesting the demographic and descriptive characteristics of data, and conducted t-test and One-Way ANOVA at 5% of significance level to figure out the degree of perception and social demand of dental hygienists depending on customers' reason for visiting dentists, and also conducted regression analysis to find the effect of the perception of dental hygienist on patient's social demand of dental hygienist. The result suggests that as the perception of the dental hygienists' role, the social demand for dental hygienists' image increases, but as perception of dental hygienists' image increases, the social demand of dental hygienists' image decreases. Therefore, it suggests that as the knowledge about dental hygienists increases, patients demand their service more, while the perception of their image lowers the social demand for their image. It turns out that as the knowledge of dental hygienists increase, the social demand for the knowledge also increases.

Study on the Optimum Planting Density of Pot Seedling for Mid-Late Maturing Rice Variety in Wheat-Rice Double Cropping System in Honam Plain Area (호남평야지 밀-벼 이모작에서 중만생종 벼 품종의 폿트묘 적정 재식밀도 구명)

  • Kang, Shin-Gu;Kim, Young-Doo;Ku, Bon-Il;Sang, Wan-Gyu;Lee, Min-Hee;Park, Hong-Kyu;Shon, Ji-Young;Yang, Woon-Ho;Lee, Jeom-Ho
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.60 no.3
    • /
    • pp.257-265
    • /
    • 2015
  • This experiment was carried out to determine the optimum planting density for rice pot seedling cultivation in wheat-rice double cropping system in Honam plain area. A mid-late maturing rice variety 'Chinnong' was raised in pot seedling tray and conventional tray for 30 days, and then transplanted on June 25 in 2012 and 2013. Four different planting densities (15.2, 18.9, 21.6, and 25.3 hills per $m^2$) in pot seedlings were applied as treatment. Conventional tray seedling was implicated as control at a single planting density of 27.8 hills per $m^2$. In this experiment, the number of effective tillers was increased as planting density increasing, but stem diameter was decreased. Pot seedling showed higher stem diameter and effective tillers than the control. Heading dates of pot seedling plots were not significantly different between the planting densities but 2 days faster than the control. Culm length, number of panicles, panicle length, and ripening grain ratio were higher in pot seedling compared to the control, but 1000-grain weight showed no significant difference. Milled rice yields in pot seedlings ranged from 5.19 to $5.43\;t\;ha^{-1}$, and the highest yield was observed in 21.6 hills per $m^2$. Head rice ratios in pot seedlings and the controls were not significantly different. Above results on planting density of rice pot seedling cultivation would be applicable to wheat-rice double cropping and also to late transplanting cultivation of rice single cropping.