• Title/Summary/Keyword: IL-6 and IL-10

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Mercury Contents of Paddy Soil in Korea and its Uptake to Rice Plant (우리나라 논 토양 중 수은함량과 벼 흡수이행)

  • Park, Sang-Won;Yang, Ju-Seok;Kim, Jin-Kyoung;Park, Byung-Jun;Kim, Won-Il;Choi, Ju-Hyeon;Kwon, Oh-Kyung;Ryu, Gab-Hee
    • Journal of Food Hygiene and Safety
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    • v.23 no.1
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    • pp.6-14
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    • 2008
  • Objective of this study was to investigate the residual levels of mercury (Hg) in soil for "Top-rice" area and its uptake into rice plant for making sure food safety as compared to "Top-rice" & common rice produced from 2005 to 2006. Hg was analyzed with the direct mercury analyzer (DMA 80, Milestone, Italy), which implements the US/EPA method 7473. The average concentration of Hg in paddy soil was 0.031 mg/kg, which was below at 1/25-1/65 fold of the threshold levels (concern level 4 mg/kg, action level 10 mg/kg) for soil contamination designated by "The Soil Environment Conservation Law" in Korea. The maximum residue level (MRLs) for Hg residue in the polished rice is not designated in Korea. Therefore, Hg contents in the polished rice of "Top-rice" brand and common rice were compared to other country's criteria. Hg contents in the polished rice of "Top-rice" brand was 0.0018 mg/kg, which was lower at 1/10-1/30 fold than the MRLs, 0.02 mg/kg of China criteria and 0.05 mg/kg of Taiwan criteria, respectively. Hg were 0.02788, 0.00896, 0.00182, 0.00189, 0.00166, 0.00452 and 0.00145 mg/kg in soil, rice straw, unhulled rice, rice hulls, brown rice, rice bran, and polished rice produced in 2006 "Top-rice" area, respectively. For the ratio of Hg as compared to Hg contents in soil, there were 0.321 of rice straw ${\gg}$ 0.162 of rice bran ${\gg}$ 0.068 of rice hulls > 0.065 of unhulled rice > 0.060 of brown rice> 0.052 of polished rice. And, the slope of Hg uptakes was steeped as following order; rice straw ${\gg}$ rice bran ${\gg}$ rice hulls > unhulled rice > brown rice > polished rice. It means that the more slope steeped was the more uptakes. For the distribution of Hg uptaken, there was 83.8% into rice straw, and 16.2% into unhulled rice, 2.8% into rice hulls, 12.4% into brown rice, 3.5% into rice bran and 9.7% into polished rice. Consequently, it was appeared that the Hg contamination in the polished rice should not be worried in Korea.

Antioxidant and antiproliferating effects of Setaria italica, Panicum miliaceum and Sorghum bicolor extracts on prostate cancer cell lines (조, 기장, 수수 추출물의 항산화 효과 및 전립선 암세포주 증식 억제 효능)

  • Kim, Jeong-Ho;Cho, Hyun-Dong;Hong, Seong-Min;Lee, Ju-Hye;Lee, Yong-Seok;Kim, Du-Hyun;Seo, Kwon-Il
    • Food Science and Preservation
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    • v.23 no.7
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    • pp.1033-1041
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    • 2016
  • In this study, we evaluated antioxidant and antiproliferating effects of Setaria italica extract (SIE), Panicum miliaceum extract (PME) and Sorghum bicolor extract (SBE). Antioxidant effects of these extracts were determined by assessing DPPH radical scavenging activity, $ABTS^+$ radical scavenging activity, reducing power and superoxide dismutase (SOD)-like activity. From high concentrations ($1,000{\mu}g/mL$) of each extract at DPPH radical scavenging activities of SIE, PME and SBE were 10.5%, 5.5% and 86.8% respectively, $ABTS^+$ radical activities were 4.92%, 5.9% and 62.3% respectively, reducing powers (OD 700) were 0.15, 0.18 and 1.7 respectively, and SOD-like activities were 17.0%, 15.9% and 38.6% respectively. In addition, SBE significantly decreased the cell viability of androgen-sensitive lymph node metastasis type of prostate cancer (LNCaP) cells in a dose-dependent manner. Morphological study of SBE-treated LNCaP cells revealed distorted and shrunken cell masses. SBE-induced cell death was confirmed by observation of nuclear condensation and increased formation of apoptotic bodies. The antiproliferative effect of SBE seems to be associated with the antioxidant activity of its polyphenol content. The results of this study indicate that SBE can exert antioxidant and antiproliferative effects and may be as a useful food material.

A Survey of Disease Occurrence in Korean Black Goats (흑염소 사육농가의 질병발생 실태조사)

  • Choe, Chang-Yong;Kang, Da-Won;Choi, Sun-Ho;Cho, Chang-Yeon;Jung, Byeong-Yeal;Son, Jun-Kyu;Ryu, Il-Sun;Hu, Tai-Young;Jung, Young-Hun;Kang, Seog-Jin;Do, Youn-Jeong;Kim, Ui-Hyung;Park, Yong-Sang;Son, Dong-Soo
    • Journal of Veterinary Clinics
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    • v.29 no.2
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    • pp.160-164
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    • 2012
  • The goat industry has been developing for many years in Korea to meet demands for food and medicine. However, many complicated patterns of disease have arisen in goat farms as this industry has developed. In this study, disease occurrence patterns in Korean black goats were surveyed in six professional farming households in Imsil and Soonchang in the Jeonbuk province and in Hamyang and Sachon in the Gyeongnam province to understand and extend the goat disease database. We observed morbidity rates between 2.0% and 9.8% for adult goats and between 2.9% and 68.3% for kids. Kids showed a markedly higher incidence of disease when compared to adults. The rate of disease occurrence was 40.0% for floppy kid syndrome (FKS), 37.7% for diarrhea, 16.0% for respiratory disease, and 1.9% for skin disease. The observed mortality rates were 0.7% ~ 10.0%, and 2.2% ~ 24.9% for adult goats and kids, respectively. In addition, FKS, diarrhea, and respiratory disease were observed in 38.3%, 28.9%, and 10.0%, respectively, of dead goats. In conclusion, the majority of diseases in goats occur during the neonatal period, and FKS is the highest single cause of mortality in Korean black goats. Thus careful attention must be paid to kids to reduce the goat mortality rate.

Rice Safety and Heavy Metal Contents in the Soil on "Top-Rice" Cultivation Area (탑라이스 생산지역 논토양 중 중금속 함량과 쌀의 안전성)

  • Park, Sang-Won;Yoon, Mi-Yeon;Kim, Jin-Kyoung;Park, Byung-Jun;Kim, Won-Il;Shin, Joung-Du;Kwon, Oh-Kyung;Chung, Duck-Hwa
    • Journal of Food Hygiene and Safety
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    • v.23 no.3
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    • pp.239-247
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    • 2008
  • Objective of this study was to investigate residual the levels of heavy metals in rice grain and soils of "Top-Rice" and common rice cultivation areas from 2005 to 2007. Soil and rice grain samples were taken from 33 "Top-rice" areas and neighboring paddies, and analyzed for the elements using ICP-OES and ICP-TOF-MS after acid digestion. A concentration of arsenic in paddy soil was 1.33 mg/kg which was below 1/5-1/11 fold of the threshold levels(concern: 4 mg/kg, action: 10 mg/kg), and paddy soil was 0.06 mg/kg of Cd(cadmium) being below 1/25-1/67 fold of the limits(concern: 1.5 mg/kg, action: 4 mg/kg). A level of Cu(copper) in paddy soil was 4.57 mg/kg which was below 1/11-1/27 fold of the threshold levels(concern: 50 mg/kg, action: 125 mg/kg), and Pb(lead) concentration in paddy soil was found to be a 4.68 mg/kg. In addition, Hg(mercury) concentration in paddy soil was to be a 0.03 mg/kg, which was below 1/131-1/328 fold of the threshold levels(concern: 4 mg/kg, action: 10 mg/kg). The average concentrations of As, Cd, Cu, Pb and Hg in the polished rice samples were 0.037, 0.043, 0.280, 0.048 and 0.002 mg/kg, respectively. These levels are lower than those of other countries in rice grains. Assuming the rice consumption of 205.7 g/day by total dietary supplements in Korea, the amount of total weekly metal intake of As, Cd, Cu, Pb and Hg by polished rice were estimated to be 0.0892, 1.035, 6.712, 1.161 and 0.054 ${\mu}g/kg$ body weigh/week, respectively. The PTWI(%) of As, Cd, Cu, Pb and Hg were 5.95(inorganic arsenic), 0.26(total arsenic), 14.79, 0.19, 4.65 and 1.07% estimated to be 0.0892, 1.035, 6.712, 1.161 and 0.054 ${\mu}g/kg$ body weigh/week, respectively. In conclusion, it was appeared that the heavy metals contamination in the brown and polished rice should not be worried in Korea.

Studies on the Flowering and Maturity in Sesame (Sesamum indicum L.) IV. Effects of Foliage Clipping on the Seed Maturity (참깨의 개화.등숙에 관한 연구 IV. 적엽처리가 참깨의 등숙에 미치는 영향)

  • Lee, Jung-Il;Kang, Chul-Whan;Son, Eung-Ryong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.30 no.2
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    • pp.165-173
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    • 1985
  • The objectives of the study were to investigate the effects of foliage clipping on photosynthesis and grain filling for branch and non branch types under the polyethylene film mulch and non mulch conditions in mono cropping and second cropping after barley in sesame (Sesamum indicum L.), and to improve poor grain filling at later flowering time utilizing these data. One thousand grain weight was more decreased in branch type than in non branch type, in polyethylene film mulch condition than in non mulch condition, and in second cropping after barley than in mono cropping by clipping lower part foliage. Twentyfive percent clipping of lower part foliage showed a little increase than no clipping. Matured grain rate also showed same tendency between branch and non branch type and between mono cropping and second cropping after barley as well as 1,000 grain weight except for polyethylene film mulch. Matured grain rate of 25% foliage clipping at 30 days after flowering in non branch type presented a little increase but decreased in branch type. Clipping of higher part leaves were so serious decrease of matured grain rate that higher part leaves at late maturing time have a major role in photosynthesis. Matured grain rate of foliage clipping at 10 days after flowering was decreased in all treatments. Chlorophyll content of higher part leaves at 50% lower part foliage clipping presented 39% increase compared to same positioned leaves of non treatment, and 66% increase by 50% higher part foliage clipping in lower part leaves. Photosynthetic activity was 58% more increased in 50% lower part foliage clipping than no clipping, but seriously decreased in 50% higher part foliage clipping. Therfore, photosynthates of remained lower part leaves could not only support their own demands, but also any contribution to translocation of photosynthates from source to sink at late maturing time. Harvest index was 28% increased in 25% lower part foliage clipping and 13% decreased in 50% higher part foliage clipping compared to no clipping. Leaf area was 48% increased in 50% lower part foliage clipping compared to the same positioned leaves of no clipping, and only 5% increased in higher part foliage clipping. Productivity by foliage clipping compared to non treatment, was highly decreased in branch type than in non branch type, in second cropping after barley than in mono cropping. Little difference was detected between polyethylene film mulch and non mulch conditions. Twenty five percentage of lower part foliage clipping on mono cropping of non branch type appeared 5% and 8% yield increase in each of polyethylene film mulch and non mulch conditions compared to no clipping, and all decreased in other treatments. Mean loss of productivity by foliage clipping at 10 days after flowering was serious than clipping at 30 days after flowering. As the result, contribution to photosynthesis of source at 10 days after flowering are larger than that at 30 days after flowering in sesame. Fifty percent lower part foliage clipping at 10 days after flowering showed so the most serious yield decrease that lower part leaves at that time were considered as the main role leaves for photosynthesis.

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Accuracy Evaluation of CT-Based Attenuation Correction in SPECT with Different Energy of Radioisotopes (SPECT/CT에서 CT를 기반으로 한 Attenuation Correction의 정확도 평가)

  • Kim, Seung Jeong;Kim, Jae Il;Kim, Jung Soo;Kim, Tae Yeop;Kim, Soo Mee;Woo, Jae Ryong;Lee, Jae Sung;Kim, Yoo Kyeong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.1
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    • pp.25-29
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    • 2013
  • Purpose: In this study, we evaluated the accuracy of CT-based attenuation correction (AC) under the conventional CT protocol (140 kVp, on average 50-60 keV) by comparing the SPECT image qualities of different energy of radioisotopes, $^{201}Tl,\;^{99m}Tc$ and $^{131}I$. Materials and Methods: Using a cylindrical phantom, three different SPECT scans of $^{201}Tl$ (70 keV, 55.5 MBq), $^{99m}Tc$ (140 keV, 281.2 MBq) and $^{131}I$ (364 keV, 96.2 MBq) were performed. The CT image was obtained with 140 kVp and 2.5 mA in GE Hawkeye 4. The OSEM reconstruction algorithm was performed with 2 iterations and 10 subsets. The experiments were performed in the 4 different conditions; non-AC and non-scatter correction (SC), only AC, only SC, AC and SC in terms of uniformity and center to peripheral ratio (CPR). Results: The uniformity was calculated from the uniform whole region in the reconstructed images. For $^{201}Tl$ and $^{99m}Tc$, the uniformities were improved by about 10-20% AC was applied, but these were decreased by about 2% as SC was applied. The uniformity of $^{131}I$ was slightly increased as both AC and SC were applied. The CPR of the reconstructed image was close to one, when AC was applied for $^{201}Tl$ and $^{99m}Tc$ scans and $^{131}I$ was distant from 1 and that is only AC. Conclusion: The image uniformity improved by AC on low energy likely to $^{201}Tl$ and $^{99m}Tc$. However, image uniformity of high energy such as $^{131}I$ was improved, when both AC and SC was applied.

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Effects of Physical Parameters on Water Quality in Agricultural Reservoirs (농업용 저수지의 물리적 인자가 수질에 미치는 영향)

  • Jeon, Ji-Hong;Ham, Jong-Hwa;Kim, Ho-Il;Hwang, Soon-Jin;Yoon, Chun-Gyeong
    • Korean Journal of Ecology and Environment
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    • v.35 no.1 s.97
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    • pp.28-35
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    • 2002
  • The effect of physical parameters on water quality was analyzed using monitoring data of 193 agricultural reservoirs. The retention time of reservoirs ($t_d$) ranged between 10 and 140 days, and the ratio of drainage area (DA) to reservoir surface area (SA) was between 10 and 120. Both ratios of DA/SA and total area (TA)/ reservoir storage (ST) in Korean agricultural reservoirs were relatively greater than those in natural lakes in other countries. As retention time was plotted against DA/SA ratio, it was shorter in Korean reservoirs than natural lakes. The semi-logarithmic relationship between TA/SA and t>$t_d$ was $t_d\;=\;42.21(TA/ST)^{-1}$ (n = 50, $R^2\;=\;0.89$). While areal loading of total phosphorus (TP) was below $4\;gTP{\cdot}m^{-2}{\cdot}yr^{-1}$ in general, it exceeded $10\;gTP{\cdot}m^{-2}{\cdot}yr^{-1}$ in reservoirs where DA/SA ratio was greater than 100, which implies that areal loading of TP increases as DA/SA ratio increases. Chl-a concentration was positively related with the mean depth of reservoir, implying the higher Chl-a concentration with deeper the mean depth. Therefore, the deeper reservoir might be advantageous in water quality management perspective if other morphological conditions are similar. The empirical regression equation using physical parameters was also suggested in the estimation of TP concentration in the reservoirs. Combined information presented in this paper might be applicable to the water quality management in agricultural reservoirs.

Study on Genetic Evaluation using Genomic Information in Animal Breeding - Simulation Study for Estimation of Marker Effects (가축 유전체정보 활용 종축 유전능력 평가 연구 - 표지인자 효과 추정 모의실험)

  • Cho, Chung-Il;Lee, Deuk-Hwan
    • Journal of Animal Science and Technology
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    • v.53 no.1
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    • pp.1-6
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    • 2011
  • This simulation study was performed to investigate the accuracy of the estimated breeding value by using genomic information (GEBV) by way of Bayesian framework. Genomic information by way of single nucleotide polymorphism (SNP) from a chromosome with length of 100cM were simulated with different marker distance (0.1cM, 0.5cM), heritabilities (0.1, 0.5) and half sibs families (20 heads, 4 heads). For generating the simulated population in which animals were inferred to genomic polymorphism, we assumed that the number of quantitative trait loci (QTL) were equal with the number of no effect markers. The positions of markers and QTLs were located with even and scatter distances, respectively. The accuracies of estimated breeding values by way of indicating correlations between true and estimated breeding values were compared on several cases of marker distances, heritabilities and family sizes. The accuracies of breeding values on animals only having genomic information were 0.87 and 0.81 in marker distances of 0.1cM and 0.5cM, respectively. These accuracies were shown to be influenced by heritabilities (0.87 at $h^2$ =0.10, 0.94 at $h^2$ =0.50). According to half sibs' family size, these accuracies were 0.87 and 0.84 in family size of 20 and 4, respectively. As half sibs family size is high, accuracy of breeding appeared high. Based on the results of this study it is concluded that the amount of marker information, heritability and family size would influence the accuracy of the estimated breeding values in genomic selection methodology for animal breeding.

Physicochemical Properties of Pork Loin Marinated with a NaCl and Sodium Tripolyphosphate Solution and Sensory Attributes of Tomato Sauce-Stewed Products using Marinated Loin (염용액으로 마리네이드 처리한 돈육 등심의 이화학적 특성과 토마토 스튜 제품에서의 관능 평가)

  • Kim, Il-Suk;Jin, Sang-Keun;Park, Ki-Hoon;Jung, Gi-Jong;Kim, Dong-Hun;Lee, M.;Choi, Jine-Sang;Hoe, Soon-Ku
    • Food Science of Animal Resources
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    • v.26 no.4
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    • pp.411-417
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    • 2006
  • This study was conducted to evaluate the physicochemical properties of pork loin marinated with a solution of Nan and sodium tripolyphosphate, and the sensory attributes of tomato sauce-stewed products using marinated loin. Pork loin samples were cut $(3{\times}3{\times}2cm)$ and assigned to 3 treatment groups [C; unmarinated control (100% distilled water), T1; 10% sodium chloride, T2; 10% sodium chloride + 3% sodium tripolyphosphate]. Samples were marinated for 24hr at $5^{\circ}C$. The uptake of marinade in the treatment groups was significantly greater (p<0.05) than that of C, however no significant difference between the two treatments was observed. Cooking losses were highest (p<0.05) for T1, while lowest (p<0.05) for T2. All marinated loins had a significantly higher (p<0.05) yield than the control. The pH of the marinade solution ranged from 7.00 for T1 to 8.47 for T2. The two marinated loins had a significantly higher (p<0.05) $pH_{24}$ than the control. The water holding capacity (WHC) was highest for T2, and lowest for T1. CIE $L^*,\;a^*,\;b^*$ tended to be slightly higher in the control than either treatment group. The shear force value $(kg/cm^2)$ of yaw meat did not differ between the control and marinated muscle samples. However, cooked meat had a significantly lower (p<0.05) shear force value in T2 than C and T1. Hardness values were significantly lower (p<0.05) for both treatments compared with the control. There were no differences in texture profile, except hardness, between the control and the two treatments. Regarding the sensory evaluation of tomato sauce-stewed products manufactured with marinated pork loin, the treatment groups scored marginally well in tenderness, juiciness and overall acceptability, while the flavor score of the control was significantly higher than those of T1 and T2.

Treatment Outcomes and Prognostic Factors in Patients with Multidrug-Resistant Tuberculosis in Korean Private Hospitals (국내 민간병원에서 치료한 다제내성결핵 환자의 치료 결과 및 예후 인자)

  • Park, Jin-Kyeong;Koh, Won-Jung;Kim, Deog-Kyeom;Kim, Eun-Kyung;Kim, Yu-Il;Kim, Hee-Jin;Kim, Tae-Hyung;Kim, Jae-Yeol;Park, Moo-Suk;Park, I-Nae;Park, Jae-Seuk;Lee, Ki-Man;Song, Sook-Hee;Lee, Jin-Hwa;Lee, Seung-Heon;Lee, Hyuk-Pyo;Yim, Jae-Joon;Lim, Jae-Min;JeGal, Yang-Jin;Jung, Ki-Hwan;Huh, Jin-Won;Choi, Jae-Chol;Shim, Tae-Sun
    • Tuberculosis and Respiratory Diseases
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    • v.69 no.2
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    • pp.95-102
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    • 2010
  • Background: The increasing rate of drug-resistant tuberculosis (TB) is a threat to the public health and TB control. In Korea, about 75~80% of TB patients are treated in private hospitals and the rate has been continuously increasing since 2000. Methods: On a retrospective basis, we enrolled 170 newly diagnosed with or retreated for multidrug-resistant TB (MDR-TB) in 2004 from 21 private hospitals. We extracted the following demographics and treatment history from patient medical records: initial treatment outcomes, cumulative survival rates, treatment outcomes, and prognostic factors. Results: Of the 170 patients, the majority were male (64.1%), the mean age was 44.5 years old, and mean body-mass-index was $20.2kg/m^2$. None of the patients tested positive for HIV. Eleven (6.5%) were confirmed to have extensively drug-resistant TB (XDR-TB) at treatment initiation. Treatment success rates were not different between XDR-TB (36.4%, 4/11) and non-XDR MDR-TB (51.6%, 82/159). Default rate was high, 21.8% (37/170). Far advanced disease on X-ray was a significant negative predictor of treatment success; advanced disease and low BMI were risk factors for all-cause mortality. Conclusion: In private hospitals in Korea, the proportion of XDR-TB in MDR-TB was comparable to previous data. The treatment success rate of MDR-/XDR-TB remains poor and the failure rate was quite high. Adequate TB control policies should be strengthened to prevent the further development and spread of MDR-/XDR-TB in Korea.