• Title/Summary/Keyword: IL-35

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AN EXTREMAL PROBLEM OF HOLOMORPHIC FUNCTIONS IN THE COMPLEX PLANE

  • Chung, Young-Bok;Park, Byoung-Il
    • 호남수학학술지
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    • 제35권4호
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    • pp.717-727
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    • 2013
  • In this paper, we study on a higher order extremal problem relating the Ahlfors map associated to the pair of a finitely connected domain in the complex plane and a point there. We show the power of the Ahlfors map with some error term which is conformally equivalent maximizes any higher order derivative of holomorphic functions at the given point in the domain.

THE CAPABILITY OF LOCALIZED NEURAL NETWORK APPROXIMATION

  • Hahm, Nahmwoo;Hong, Bum Il
    • 호남수학학술지
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    • 제35권4호
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    • pp.729-738
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    • 2013
  • In this paper, we investigate a localized approximation of a continuously differentiable function by neural networks. To do this, we first approximate a continuously differentiable function by B-spline functions and then approximate B-spline functions by neural networks. Our proofs are constructive and we give numerical results to support our theory.

Incarcerated pericecal hernia: a rare form of the internal hernia

  • Kang, Sung Il
    • Journal of Yeungnam Medical Science
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    • 제35권2호
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    • pp.236-239
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    • 2018
  • A pericecal hernia is a rare form of an internal hernia, which has been described in several case reports. We present a case of a 32-year-old woman who complained of vague abdominal pain a day prior to admission. Abdominal computed tomography revealed the presence of a pericecal hernia without bowel ischemia. The patient underwent manual hernia reduction and was discharged without complications. We describe this case in detail and provide a review of the pertinent literature.

MIA로 골관절염 유발된 동물모델에서 산수유(山茱萸) 30% Ethanol 추출물의 개선 효과 (Improvement Effect of Corni Fructus 30% Ethanol Extract by MIA-Induced Osteoarthritis Animal Model)

  • 김민주;이진아;신미래;박해진;노성수
    • 대한본초학회지
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    • 제35권1호
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    • pp.35-44
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    • 2020
  • Objectives : The objective of this study was to investigate the therapeutic effect of Corni Fructus 30% ethanol extract (CFE) on the monosodium iodoacetate (MIA)-induced osteoarthritis rats. Methods : The subjects were divided into 4 groups ; Normal group (N, n=10), MIA-induced osteoarthritis control group (Con, n=10), indomethacin 5 mg/kg treated group (INDO, n=10), CFE 200 mg/kg treated group (CFE, n=10). Blood and articulation tissues were collected after two weeks of drug administration. Oxidative stress was analyzed with reactive oxygen species (ROS), peroxynitrite (ONOO-). And the Nuclear factor erythroid-2 (Nrf2), heme oxygenase-1 (HO-1), superoxide dismutase (SOD), catalase, glutathione peroxidase-1/2 (GPx-1/2), Nuclear Factor Kappa B p65 (NF-κBp65), cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), tumor necrosis factor-alpha (TNFα), interleukin-6 (IL-6), Interleukin 1β (IL-1β), matrix metalloproteinase-1 (MMP-1), and tissue inhibitor of metalloproteinases-1 (TIMP-1) were investigated by western blot. Results : The administration of CFE showed a significant reduction of changes in relative hind paw weight distribution. Reactive oxygen species (ROS) and peroxy nitrite (ONOO-) levels of articulation tissues were significantly decreased in CFE compared to the control group. Western blot measurements of Nrf2, HO-1, SOD, catalase, GPx-1/2 showed that the CFE group was increased compared to the Con group. And western blot measurements of NF-κBp65, COX-2, iNOS, TNFα, IL-6, IL-1β showed that the CFE group was reduced compared to the Con group. Also CFE group decreased MMP-1 and increased TIMP-1. Conclusion : Based on the above results, it can be seen that osteoarthritis is improved when Corni Fructus 30% ethanol extract treated.

아토피양(樣) 피부염 NC/Nga생쥐에서 가감소독음(加減消毒飮)의 투여가 피부염에 미치는 영향 (Effects of Kakamsodokum (KKSDU) on Atopic Dermatitis-like Skin Lesions in NC/Nga Mouse)

  • 송현지;한재경;김윤희
    • 대한한방소아과학회지
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    • 제23권1호
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    • pp.23-35
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    • 2009
  • Objectives The purpose of this study is to investigate the effect of Kakamsodokum (KKSDU) on atopic dermatitis in an in-vitro experiment using an NC/Nga atopic dermatitis mouse, which has histological and clinical similarities to the condition in humans. Methods We evaluated $IL-1{\beta}$, IL-6, $TNF-{\alpha}$, $TGF-{\beta}$, IL-10 mRNA, CD4+/$IFN-{\gamma}+$, and CD4+CD25+foxp3+ in B and T cells of NC/Nga atopic dermatitis mouse by real-time PCR and intracellular staining in vitro. Results KKSDU medicines supressed $IL-1{\beta}$, IL-6, $TNF-{\alpha}$, $TGF-{\beta}$ mRNA and increased IL-10 mRNA in B cells. CD4+/$IFN-{\gamma}+$ and CD4+CD25+foxp3+ in T cells were increased by KKSDU. Conclusions KKSDU on atopic dermatitis might be very effective to the atopic dermatitis treatment.

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Dynamic Patterns of Systemic Innate Immunity and Inflammatory Associated Factors in Experimental Caprine Coccidiosis

  • Tadayon, Shabnam;Razavi, Seyed Mostafa;Nazifi, Saeed
    • Parasites, Hosts and Diseases
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    • 제54권6호
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    • pp.719-724
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    • 2016
  • The present study was designed to assess the dynamic patterns of pro-inflammatory cytokines, including $IFN-{\gamma}$, $TNF-{\alpha}$, IL-4, IL-6, acute phase protein (${\alpha}1$-acid-glycoprotein, AGP), and an inflammation associated factor (adenosine deaminase; ADA) following experimental caprine coccidiosis. Ten kids aging from 2 to 4 months were infected orally with $5{\times}10^4$ sporulated oocysts and 10 animals served as controls. Blood samples were collected in both groups before infection and at days 3, 7, 14, 21, 28, and 35 post-infection (PI), and the levels of above-mentioned factors were measured. $IFN-{\gamma}$, $TNF-{\alpha}$, IL-4, IL-6, AGP, and ADA activities were significantly higher in infected animals from day 7 PI (P<0.05). In conclusion, the circulatory levels of most systemic inflammatory markers, including pro-inflammatory cytokines ($IFN-{\gamma}$, $TNF-{\alpha}$, IL-4, IL-6), AGP, and ADA increased significantly starting from day 3 to day 7 PI in caprine coccidiosis.